Compounds > cholestyramine resin

Page last updated: 2024-09-03

cholestyramine resin and leflunomide

cholestyramine resin has been researched along with leflunomide in 12 studies

Compound Research Comparison

Studies (cholestyramine resin)	Trials (cholestyramine resin)	Recent Studies (post-2010) (cholestyramine resin)	Studies (leflunomide)	Trials (leflunomide)	Recent Studies (post-2010) (leflunomide)
2,669	342	190	1,725	173	659

Protein Interaction Comparison

Protein	Taxonomy	cholestyramine resin (IC50)	leflunomide (IC50)
Dihydroorotate dehydrogenase (quinone), mitochondrial	Mus musculus (house mouse)		0.03
Cytochrome P450 1A2	Homo sapiens (human)		0.5
Aldo-keto reductase family 1 member B1	Rattus norvegicus (Norway rat)		4.63
Sodium-dependent noradrenaline transporter	Homo sapiens (human)		4.63
Sodium-dependent dopamine transporter	Homo sapiens (human)		2.884
Dihydroorotate dehydrogenase (quinone), mitochondrial	Homo sapiens (human)		5.4
Dihydroorotate dehydrogenase (quinone), mitochondrial	Rattus norvegicus (Norway rat)		0.009

Research

Studies (12)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	8 (66.67)	29.6817
2010's	2 (16.67)	24.3611
2020's	2 (16.67)	2.80

Authors

Authors	Studies
Abruzzo, JL; Koenig, AS	1
Agúndez, JA; Díaz-Rubio, M; Fernández-Gutiérrez, B; Ladero, JM; Ortega, L; Sevilla-Mantilla, C	1
Dissemond, J; Goos, M; Knab, J	1
Adachi, D; Akiba, H; Akiyama, Y; Hirano, M; Mimura, T; Takeishi, M	1
Handler, RP	1
Hagiyama, H; Harigai, M; Iwai, H; Miyasaka, N; Mizoguchi, F; Ochi, S; Oka, T	1
Baaj, M; El Haouri, M; Hadri, L; Hassikou, H; Safi, S; Tabache, F	1
Chu, CM; Kan, CH; Ng, WL; Tsui, HS; Wong, SP	1
Braddock, SR; Chambers, CD; Jin, S; Johnson, DL; Jones, KL; Lopez-Jimenez, J; Luo, YJ; Mirrasoul, N; Robinson, LK; Salas, E; Xu, R	1
Fraser, R; Kiser, TH; Kurche, J; Lara, A; Laub, M; Reynolds, PM	1
Cho, T; Maljaars, J; Ortega-Gutierrez, S; Shaban, A	1
Alothman, R; Amiri, N; Lepik, C; Waterman, E; Yeung, J	1

Reviews

1 review(s) available for cholestyramine resin and leflunomide

Article	Year
Use of a Cholestyramine Washout in a Patient With Septic Shock on Leflunomide Therapy: A Case Report and Review of the Literature. Journal of intensive care medicine, 2016, Volume: 31, Issue:6 Topics: Aged; Antirheumatic Agents; Cholestyramine Resin; Female; Humans; Isoxazoles; Leflunomide; Prosthesis-Related Infections; Renal Replacement Therapy; Shock, Septic; Treatment Outcome	2016

Other Studies

11 other study(ies) available for cholestyramine resin and leflunomide

Article	Year
Leflunomide induced fevers, thrombocytosis, and leukocytosis in a patient with relapsing polychondritis. The Journal of rheumatology, 2002, Volume: 29, Issue:1 Topics: Anti-Inflammatory Agents; C-Reactive Protein; Cholestyramine Resin; Drug Therapy, Combination; Fever; Humans; Isoxazoles; Leflunomide; Leukocyte Count; Leukocytosis; Male; Middle Aged; Photophobia; Platelet Count; Polychondritis, Relapsing; Thrombocytosis; Treatment Failure	2002
Leflunomide-induced acute hepatitis. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2004, Volume: 36, Issue:1 Topics: Adjuvants, Immunologic; Aged; Anion Exchange Resins; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Cholestyramine Resin; Female; Humans; Isoxazoles; Leflunomide; Liver	2004
Successful treatment of a leg ulcer occurring in a rheumatoid arthritis patient under leflunomide therapy. Journal of the European Academy of Dermatology and Venereology : JEADV, 2005, Volume: 19, Issue:2 Topics: Aged; Arthritis, Rheumatoid; Cholestyramine Resin; Debridement; Female; Humans; Immunosuppressive Agents; Isoxazoles; Leflunomide; Leg Ulcer; Skin Transplantation; Vasculitis; Wound Healing	2005
Leflunomide induced acute interstitial pneumonia. The Journal of rheumatology, 2005, Volume: 32, Issue:6 Topics: Adjuvants, Immunologic; Arthritis, Rheumatoid; Cholestyramine Resin; Drug Therapy, Combination; Female; Humans; Isoxazoles; Leflunomide; Lung Diseases, Interstitial; Middle Aged; Prednisolone; Radiography, Thoracic; Treatment Outcome	2005
Leflunomide for relapsing polychondritis: successful longterm treatment. The Journal of rheumatology, 2006, Volume: 33, Issue:9 Topics: Anti-Inflammatory Agents; C-Reactive Protein; Cholestyramine Resin; Drug Therapy, Combination; Fever; Humans; Isoxazoles; Leflunomide; Leukocyte Count; Leukocytosis; Male; Middle Aged; Photophobia; Platelet Count; Polychondritis, Relapsing; Thrombocytosis; Treatment Failure	2006
Leflunomide-related acute interstitial pneumonia in two patients with rheumatoid arthritis: autopsy findings with a mosaic pattern of acute and organizing diffuse alveolar damage. Modern rheumatology, 2006, Volume: 16, Issue:5 Topics: Aged; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Autopsy; Cholestyramine Resin; Female; Humans; Isoxazoles; Leflunomide; Lung Diseases, Interstitial; Methylprednisolone; Pulmonary Alveoli; Tomography, X-Ray Computed	2006
Leflunomide-induced toxic epidermal necrolysis in a patient with rheumatoid arthritis. Joint bone spine, 2008, Volume: 75, Issue:5 Topics: Adjuvants, Immunologic; Adult; Arthritis, Rheumatoid; Cholestyramine Resin; Female; Glucocorticoids; Humans; Ion Exchange Resins; Isoxazoles; Leflunomide; Prednisolone; Stevens-Johnson Syndrome	2008
Successful treatment of leflunomide-induced acute pneumonitis with cholestyramine wash-out therapy. Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2009, Volume: 15, Issue:8 Topics: Adult; Alveolitis, Extrinsic Allergic; Anion Exchange Resins; Antirheumatic Agents; Arthritis, Rheumatoid; Cholestyramine Resin; Female; Humans; Isoxazoles; Leflunomide; Lung Diseases, Interstitial	2009
Birth outcomes in women who have taken leflunomide during pregnancy. Arthritis and rheumatism, 2010, Volume: 62, Issue:5 Topics: Adult; Anticholesteremic Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Birth Weight; Body Size; Cholestyramine Resin; Congenital Abnormalities; Female; Gestational Age; Humans; Infant, Newborn; Isoxazoles; Leflunomide; Linear Models; Multivariate Analysis; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Risk Factors	2010
Q Fever, CNS Vasculitis, and Stroke: A Case Report. The American journal of medicine, 2020, Volume: 133, Issue:12 Topics: Adult; Anti-Bacterial Agents; Arthritis, Rheumatoid; Cholestyramine Resin; Humans; Leflunomide; Male; Q Fever; Stroke; Vasculitis, Central Nervous System	2020
Leflunomide exposure through second trimester of pregnancy: A case report. Birth defects research, 2023, 10-01, Volume: 115, Issue:16 Topics: Arthritis, Rheumatoid; Cholestyramine Resin; Female; Humans; Isoxazoles; Leflunomide; Pregnancy; Pregnancy Trimester, Second	2023