Page last updated: 2024-09-03

cholecystokinin (27-33) and sincalide

cholecystokinin (27-33) has been researched along with sincalide in 37 studies

Compound Research Comparison

Studies
(cholecystokinin (27-33))
Trials
(cholecystokinin (27-33))
Recent Studies (post-2010)
(cholecystokinin (27-33))
Studies
(sincalide)
Trials
(sincalide)
Recent Studies (post-2010) (sincalide)
39004,01572533

Protein Interaction Comparison

ProteinTaxonomycholecystokinin (27-33) (IC50)sincalide (IC50)
Cholecystokinin receptor type ARattus norvegicus (Norway rat)0.0006
Cholecystokinin receptor type AHomo sapiens (human)0.0006
Gastrin/cholecystokinin type B receptorHomo sapiens (human)0.001
Gastrin/cholecystokinin type B receptorMus musculus (house mouse)0.0008
Cholecystokinin receptor type ACavia porcellus (domestic guinea pig)0.0004

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199030 (81.08)18.7374
1990's6 (16.22)18.2507
2000's1 (2.70)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chiang, E; Danho, W; Kulesha, I; Makofske, R; Olson, GL; Rusiecki, VK; Sarabu, R; Shiuey, SJ; Swistok, J; Tilley, JW1
Danho, W; Kulesha, I; Makofske, R; Michalewsky, J; Nelson, D; Shiuey, SJ; Swistok, J; Tilley, JW; Triscari, J; Wagner, R1
Berry, P; Botella, A; Bueno, L; Delvaux, M; Frexinos, J1
Galas, MC; Lignon, MF; Martinez, J; Rodriguez, M1
Aumelas, A; Galas, MC; Laur, J; Lignon, MF; Martinez, J; Rodriguez, M; Rolland, M1
Horwell, DC1
Louie, DS; Owyang, C; Williams, JA1
Baba, S; Fujii, M; Nakamura, T; Ohki, A; Oka, T; Okabayashi, Y; Otsuki, M; Sugiura, N; Yanaihara, N1
Gardner, JD; Jensen, RT; Vinayek, R1
Aumelas, A; Fulcrand, P; Galas, MC; Laur, J; Lignon, MF; Martinez, J; Rodriguez, M1
Gardner, JD; Jensen, RT; Martinez, J; Sharp, CM; Stark, HA; Sutliff, VE1
Henklein, P; Milenov, K; Nieber, K; Oehme, P; Rakovska, A2
Carty, RP; Chen, J; Murphy, RB; Pincus, MR; Scheraga, HA; Shah, D1
Davison, JS; Kerrin, JP; MacVicar, BA1
Avitable, M; Carty, RP; Chen, J; Lubowsky, J; Murphy, RB; Pincus, MR; Scheraga, HA; Shah, D1
Ahrén, B; Efendic, S; Sandberg, E; Tendler, D1
Camus, A; Rose, C; Schwartz, JC1
Ito, K; Iuchi, K; Morimoto, Y; Nitta, M; Tsukamoto, G1
Grillner, S; Hökfelt, T; Rehfeld, JF; van Dongen, PA; Verhofstad, AJ1
Fried, GM; Greeley, GH; Ogden, WD; Sakamoto, T; Thompson, JC1
Eichstädt, M; Georgi, M; Henklein, P; Treptow, K1
Crawley, JN; Gaudreau, P; St-Pierre, S1
Fried, GM; Greeley, GH; Inoue, K; Lilja, P; Thompson, JC; Wiener, I1
Milenov, E; Nieber, K; Niedrich, H; Oehme, P; Vogt, WE1
Bunney, BS; Goldstein, M; Grace, AA; Hökfelt, T; Hommer, DW; Rehfeld, J; Skirboll, LR1
Bodanszky, M; Gardner, JD; Martinez, J; Natarajan, S; Priestly, GP; Walker, MD1
Bodanszky, M; Gardner, JD; Jensen, RT; Martinez, J; Pan, GZ1
Bodanszky, M; Gardner, JD; Martinez, J; Mutt, V; Walker, MD; Winternitz, F1
Bodanszky, M; Collins, SM; Gardner, JD; Jensen, RT; Martinez, J; Villanueva, ML1
Baile, CA; McLaughlin, CL; Peikin, SR1
Bui, ND; Christophe, J; Deschodt-Lanckman, M; Noyer, M1
Kimura, I; Kimura, M; Kobayashi, S1
Goldman, SA; Lorenz, DN1
Jansen, JB; Lamers, CB1
Belleney, J; Durieux, C; Fournie-Zaluski, MC; Lallemand, JY; Roques, BP1
Owyang, C; Song, I; Taylor, LP; Tsunoda, Y1

Other Studies

37 other study(ies) available for cholecystokinin (27-33) and sincalide

ArticleYear
Structure activity of C-terminal modified analogs of Ac-CCK-7.
    International journal of peptide and protein research, 1992, Volume: 39, Issue:4

    Topics: Amino Acid Sequence; Amylases; Animals; Cattle; Molecular Sequence Data; Pancreas; Peptide Fragments; Phenylalanine; Rats; Receptors, Cholecystokinin; Sincalide; Structure-Activity Relationship

1992
Structure activity studies of tryptophan30 modified analogs of Ac-CCK-7.
    International journal of peptide and protein research, 1992, Volume: 39, Issue:4

    Topics: Amino Acid Sequence; Animals; Appetite Depressants; Blood Proteins; Cattle; Corpus Striatum; Molecular Sequence Data; Pancreas; Peptide Fragments; Rats; Sincalide; Structure-Activity Relationship; Tryptophan

1992
Cholecystokinin and gastrin induce cell contraction in pig ileum by interacting with different receptor subtypes.
    Gastroenterology, 1992, Volume: 102, Issue:3

    Topics: Animals; Calcium; Cholecystokinin; Dose-Response Relationship, Drug; Gastrins; Ileum; In Vitro Techniques; Male; Muscle Contraction; Pentagastrin; Peptide Fragments; Proglumide; Receptors, Cholecystokinin; Sincalide; Swine; Tetragastrin

1992
Correlation between phospholipid breakdown, intracellular calcium mobilization and enzyme secretion in rat pancreatic acini treated with Boc-[Nle28, Nle31]-CCK-7 and JMV180, two cholecystokinin analogues.
    Cellular signalling, 1990, Volume: 2, Issue:4

    Topics: Amylases; Animals; Calcium; In Vitro Techniques; Intracellular Fluid; Male; Pancreas; Peptide Fragments; Phospholipids; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Sincalide

1990
Synthesis and biological activity of 2-phenylethyl ester analogues of C-terminal heptapeptide of cholecystokinin modified in Trp 30 region.
    International journal of peptide and protein research, 1991, Volume: 38, Issue:2

    Topics: Amino Acid Sequence; Amylases; Animals; Binding Sites; Brain; Dose-Response Relationship, Drug; Guinea Pigs; Magnetic Resonance Spectroscopy; Male; Membranes; Molecular Sequence Data; Oligopeptides; Pancreas; Peptide Fragments; Phenylethyl Alcohol; Rats; Receptors, Cholecystokinin; Sincalide

1991
Development of CCK-B antagonists.
    Neuropeptides, 1991, Volume: 19 Suppl

    Topics: Amino Acid Sequence; Animals; Binding Sites; Blood-Brain Barrier; Cerebral Cortex; Cholecystokinin; Drug Design; Indoles; Meglumine; Mice; Molecular Sequence Data; Peptide Fragments; Receptors, Cholecystokinin; Sincalide; Structure-Activity Relationship

1991
Action of pancreatic polypeptide on rat pancreatic secretion: in vivo and in vitro.
    The American journal of physiology, 1985, Volume: 249, Issue:4 Pt 1

    Topics: Amylases; Animals; Bile; Dibutyryl Cyclic GMP; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Nerve Tissue Proteins; Neuropeptide Y; Pancreas; Pancreatic Polypeptide; Peptide Fragments; Peptide YY; Peptides; Proteins; Rats; Rats, Inbred Strains; Sincalide; Stimulation, Chemical

1985
Action of cholecystokinin analogues on exocrine and endocrine rat pancreas.
    The American journal of physiology, 1986, Volume: 250, Issue:4 Pt 1

    Topics: Amylases; Animals; Cholecystokinin; Insulin; Insulin Secretion; Pancreas; Peptide Fragments; Rats; Sincalide; Tetragastrin

1986
Role of sulfate ester in influencing biologic activity of cholecystokinin-related peptides.
    The American journal of physiology, 1987, Volume: 252, Issue:2 Pt 1

    Topics: Amylases; Animals; Carboxylic Acids; Cholecystokinin; Esters; Guinea Pigs; Male; Mice; Pancreas; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Sincalide; Structure-Activity Relationship; Sulfates

1987
2-Phenylethyl ester and 2-phenylethyl amide derivative analogues of the C-terminal hepta- and octapeptide of cholecystokinin.
    International journal of peptide and protein research, 1988, Volume: 32, Issue:5

    Topics: Amino Acid Sequence; Amylases; Animals; Biological Assay; Brain; Cell Membrane; Chemical Phenomena; Chemistry, Physical; Esters; Guinea Pigs; Molecular Sequence Data; Pancreas; Peptide Fragments; Phenethylamines; Rats; Sincalide; Structure-Activity Relationship

1988
CCK-JMV-180: a peptide that distinguishes high-affinity cholecystokinin receptors from low-affinity cholecystokinin receptors.
    Biochimica et biophysica acta, 1989, Feb-09, Volume: 1010, Issue:2

    Topics: Amylases; Animals; Binding, Competitive; Kinetics; Male; Pancreas; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Sincalide

1989
Responses of guinea-pig gastric, ileal and gall bladder smooth muscle to desamino-cholecystokinin-octapeptide (CCK 7).
    Methods and findings in experimental and clinical pharmacology, 1988, Volume: 10, Issue:8

    Topics: Animals; Atropine; Bucladesine; Female; Gallbladder; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Peptide Fragments; Sincalide; Stomach; Tetrodotoxin

1988
Conformational analysis of possible biologically active (receptor-bound) conformations of peptides derived from cholecystokinin, cerulein and little gastrin and the opiate peptide, Met-enkephalin.
    Peptides, 1988, Volume: 9 Suppl 1

    Topics: Amino Acid Sequence; Ceruletide; Cholecystokinin; Enkephalin, Methionine; Gastrins; Models, Molecular; Molecular Sequence Data; Neuropeptides; Peptide Fragments; Peptides; Protein Conformation; Receptors, Cholecystokinin; Sequence Homology, Amino Acid; Sincalide; Tetragastrin

1988
Inhibition of synaptic transmission in the hippocampus by cholecystokinin (CCK) and its antagonism by a CCK analog (CCK27-33).
    Brain research, 1987, Mar-17, Volume: 406, Issue:1-2

    Topics: Animals; Depression, Chemical; Evoked Potentials; Hippocampus; Peptide Fragments; Proglumide; Rats; Rats, Inbred Strains; Sincalide; Synaptic Transmission

1987
On the biologically active structures of cholecystokinin, little gastrin, and enkephalin in the gastrointestinal system.
    Proceedings of the National Academy of Sciences of the United States of America, 1987, Volume: 84, Issue:14

    Topics: Amino Acid Sequence; Benzodiazepines; Ceruletide; Enkephalin, Methionine; Gastrins; Indoles; Models, Molecular; Peptide Fragments; Protein Binding; Protein Conformation; Receptors, Cholecystokinin; Receptors, Opioid; Sincalide; Tetragastrin

1987
Cholecystokinin (CCK)-33 stimulates insulin secretion from the perfused rat pancreas: studies on the structure-activity relationship.
    Pharmacology & toxicology, 1988, Volume: 63, Issue:1

    Topics: Animals; Binding Sites; Cholecystokinin; Insulin; Insulin Secretion; Male; Pancreas; Peptide Fragments; Perfusion; Rats; Rats, Inbred Strains; Sincalide; Structure-Activity Relationship; Tetragastrin; Time Factors

1988
A serine peptidase responsible for the inactivation of endogenous cholecystokinin in brain.
    Proceedings of the National Academy of Sciences of the United States of America, 1988, Volume: 85, Issue:21

    Topics: Animals; Cerebral Cortex; Cholecystokinin; Chromatography, High Pressure Liquid; Peptide Fragments; Rats; Serine Endopeptidases; Serine Proteinase Inhibitors; Sincalide

1988
Synthesis and analgesic activity of cholecystokinin-heptapeptide analogs with N-terminal substitution.
    Chemical & pharmaceutical bulletin, 1988, Volume: 36, Issue:3

    Topics: Analgesics; Animals; Chemical Phenomena; Chemistry; Mice; Peptide Fragments; Sincalide

1988
Suc-Tyr(SE)-Met-Gly-Trp-Met-Asp-beta-phenethylamide(410): a competitive antagonist of cholecystokinin-induced contractions in smooth muscles in vitro.
    Methods and findings in experimental and clinical pharmacology, 1987, Volume: 9, Issue:7

    Topics: Animals; Dose-Response Relationship, Drug; Gallbladder; Guinea Pigs; Ileum; In Vitro Techniques; Muscle Contraction; Peptide Fragments; Sincalide; Stomach

1987
A cholecystokinin-like peptide is present in 5-hydroxytryptamine neurons in the spinal cord of the lamprey.
    Acta physiologica Scandinavica, 1985, Volume: 125, Issue:3

    Topics: Animals; Fluorescent Antibody Technique; Lampreys; Neurons; Peptide Fragments; Serotonin; Sincalide; Spinal Cord

1985
Experimental evidence for a vagally mediated and cholecystokinin-independent enteropancreatic reflex.
    Annals of surgery, 1985, Volume: 202, Issue:1

    Topics: Animals; Bombesin; Cholecystokinin; Dogs; Duodenum; Female; Male; Oleic Acid; Oleic Acids; Pancreas; Pancreatic Fistula; Pancreatic Polypeptide; Peptide Fragments; Proteins; Reflex; Sincalide; Stimulation, Chemical; Vagotomy; Vagus Nerve

1985
[Effect of desaminoocta-pancreozymin on the locomotor activity of rats].
    Biomedica biochimica acta, 1985, Volume: 44, Issue:10

    Topics: Animals; Eating; Male; Motor Activity; Peptide Fragments; Rats; Rats, Inbred Strains; Sincalide; Time Factors

1985
Analysis of the behavioral activity of C- and N-terminal fragments of cholecystokinin octapeptide.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 230, Issue:2

    Topics: Amino Acid Sequence; Animals; Cholecystokinin; Exploratory Behavior; Feeding Behavior; Male; Mice; Molecular Weight; Peptide Fragments; Receptors, Cell Surface; Receptors, Cholecystokinin; Sincalide

1984
Release of cholecystokinin in response to food and intraduodenal fat in pigs, dogs and man.
    Surgery, gynecology & obstetrics, 1984, Volume: 159, Issue:6

    Topics: Adult; Animals; Cholecystokinin; Corn Oil; Dietary Fats; Dogs; Female; Food; Humans; Intubation, Gastrointestinal; Male; Oils; Peptide Fragments; Radioimmunoassay; Sincalide; Swine; Time Factors

1984
Effect of desamino-cholecystokinin-octapeptide (CCK-7) on the intraluminal pressure and myoelectrical activity of the gall-bladder, stomach, and small intestine in conscious dogs.
    British journal of pharmacology, 1983, Volume: 80, Issue:4

    Topics: Animals; Cholecystokinin; Dogs; Gallbladder; Gastrointestinal Motility; Intestine, Small; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Peptide Fragments; Pressure; Sincalide; Stomach; Vagotomy

1983
Peptide-monoamine coexistence: studies of the actions of cholecystokinin-like peptide on the electrical activity of midbrain dopamine neurons.
    Neuroscience, 1981, Volume: 6, Issue:11

    Topics: Animals; Cholecystokinin; Evoked Potentials; Fluorescent Antibody Technique; Male; Neurons; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sincalide; Substantia Nigra; Tegmentum Mesencephali; Tyrosine 3-Monooxygenase

1981
The importance of the amino acid in position 27 of cholecystokinin in determining its biological activity on pancreatic acini.
    Biochimica et biophysica acta, 1980, Jul-03, Volume: 630, Issue:3

    Topics: Amino Acid Sequence; Amylases; Animals; Cholecystokinin; Dibutyryl Cyclic GMP; Guinea Pigs; Male; Pancreas; Peptide Fragments; Sincalide

1980
The importance of the amino acid in position 32 of cholecystokinin in determining its interaction with cholecystokinin receptors on pancreatic acini.
    Biochimica et biophysica acta, 1981, Dec-18, Volume: 678, Issue:3

    Topics: Alanine; Amino Acid Sequence; Amino Acids; Amylases; Animals; Aspartic Acid; Cholecystokinin; Guinea Pigs; Male; Pancreas; Peptide Fragments; Receptors, Cell Surface; Receptors, Cholecystokinin; Sincalide; Structure-Activity Relationship

1981
Synthesis and some pharmacological properties of Z-Tyr(SO3H)-Met-Gly-Trp-Met-Asp(Phe-NH2)-OH, a 32-beta-aspartyl analogue of cholecystokinin (pancreozymin) 27-33.
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:5

    Topics: Amylases; Anesthesia; Animals; Cats; Cholecystokinin; Gallbladder; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Pancreas; Peptide Fragments; Proteins; Sincalide

1982
Selective modification of the ability of cholecystokinin to cause residual stimulation of pancreatic enzyme secretion.
    The American journal of physiology, 1982, Volume: 243, Issue:3

    Topics: Amylases; Animals; Aspartic Acid; Cholecystokinin; Guinea Pigs; Isomerism; Pancreas; Peptide Fragments; Sincalide; Structure-Activity Relationship

1982
Decreased pancreatic CCK receptor binding and CCK-stimulated amylase release in Zucker obese rats.
    Physiology & behavior, 1984, Volume: 32, Issue:6

    Topics: Amylases; Animals; Body Weight; Carbachol; Culture Techniques; DNA; Dose-Response Relationship, Drug; Esters; Female; Gabexate; Guanidines; Pancreas; Peptide Fragments; Rats; Rats, Zucker; Receptors, Cell Surface; Receptors, Cholecystokinin; Sincalide

1984
Degradation of cholecystokinin-like peptides by a crude rat brain synaptosomal fraction: a study by high pressure liquid chromatography.
    Regulatory peptides, 1981, Volume: 2, Issue:1

    Topics: Animals; Brain; Cations, Divalent; Cholecystokinin; Chromatography, High Pressure Liquid; Gastrins; Kinetics; Peptide Fragments; Protease Inhibitors; Puromycin; Rats; Sincalide; Synaptosomes; Tetragastrin

1981
Relationship between cyclic AMP-dependent protein kinase activation and Ca uptake increase of sarcoplasmic reticulum fraction of hog biliary muscles relaxed by cholecystokinin-C-terminal peptides.
    Biochemical pharmacology, 1982, Oct-01, Volume: 31, Issue:19

    Topics: Animals; Biliary Tract; Calcium; Cholecystokinin; Cyclic AMP; Enzyme Activation; In Vitro Techniques; Muscle, Smooth; Peptide Fragments; Protein Kinases; Sarcoplasmic Reticulum; Sincalide; Swine

1982
Vagal mediation of the cholecystokinin satiety effect in rats.
    Physiology & behavior, 1982, Volume: 29, Issue:4

    Topics: Adrenergic Fibers; Afferent Pathways; Animals; Cholecystokinin; Eating; Injections, Intraperitoneal; Injections, Intraventricular; Male; Muridae; Peptide Fragments; Satiation; Satiety Response; Sincalide; Spinal Cord; Splanchnic Nerves; Vagus Nerve

1982
Characterization of antisera to cholecystokinin by use of different cholecystokinin labels.
    Journal of immunological methods, 1984, Jun-08, Volume: 71, Issue:1

    Topics: Animals; Binding Sites, Antibody; Cholecystokinin; Gastrins; Guinea Pigs; Humans; Immune Sera; Iodine Radioisotopes; Isotope Labeling; Peptide Fragments; Rabbits; Sincalide; Succinimides; Swine

1984
1H NMR conformational study of sulfated and non-sulfated cholecystokinin fragment CCK27-33: influence of the sulfate group on the peptide folding.
    Biochemical and biophysical research communications, 1983, Jul-29, Volume: 114, Issue:2

    Topics: Amino Acid Sequence; Cholecystokinin; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Peptide Fragments; Protein Conformation; Sincalide; Structure-Activity Relationship; Sulfuric Acids

1983
Structure-activity function for binding and signaling in CHO-K1 and COS-7 cells expressing the cholecystokinin A receptor.
    Biochemical and biophysical research communications, 2004, Feb-13, Volume: 314, Issue:3

    Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Calcium; CHO Cells; COS Cells; Cricetinae; Devazepide; Inositol 1,4,5-Trisphosphate; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Protein Binding; Radioligand Assay; Rats; Receptor, Cholecystokinin A; RNA, Messenger; Signal Transduction; Sincalide; Structure-Activity Relationship; Transfection

2004