chlorzoxazone and trimethadione

chlorzoxazone has been researched along with trimethadione in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's2 (25.00)18.2507
2000's1 (12.50)29.6817
2010's4 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bender, AD; Greene, L; Macko, E; Tedeschi, RE; Wilfon, G1
Breimer, DD; Tanaka, E1
Fischer, NE; Inaba, T; Iwase, M; Kurata, N; Nishimura, Y; Tang, BK; Yasuhara, H1
Misawa, S; Tanaka, E; Terada, M1

Reviews

3 review(s) available for chlorzoxazone and trimethadione

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
In vivo function tests of hepatic drug-oxidizing capacity in patients with liver disease.
    Journal of clinical pharmacy and therapeutics, 1997, Volume: 22, Issue:4

    Topics: Aminopyrine; Antipyrine; Breath Tests; Caffeine; Chlorzoxazone; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Erythromycin; Humans; Liver Diseases; Liver Function Tests; Trimethadione

1997
Cytochrome P450 2E1: its clinical and toxicological role.
    Journal of clinical pharmacy and therapeutics, 2000, Volume: 25, Issue:3

    Topics: Anesthetics; Animals; Chlorzoxazone; Cytochrome P-450 CYP2E1; Ethanol; Humans; Isoenzymes; Noxae; Substrate Specificity; Trimethadione

2000

Other Studies

5 other study(ies) available for chlorzoxazone and trimethadione

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Pharmacological properties of the isopropyl ester of o-sulfamoyl-benzoic acid.
    Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 168, Issue:1

    Topics: Animals; Behavior, Animal; Benzoates; Carbamates; Carisoprodol; Chlordiazepoxide; Chlormezanone; Chlorzoxazone; Dogs; Drug Antagonism; Electroshock; Male; Mephenesin; Meprobamate; Methocarbamol; Mice; Muscles; Pentobarbital; Phenethylamines; Phenobarbital; Phenytoin; Rats; Reflex; Seizures; Sleep; Strychnine; Trimethadione; Zoxazolamine

1967
Trimethadione metabolism by human liver cytochrome P450: evidence for the involvement of CYP2E1.
    Xenobiotica; the fate of foreign compounds in biological systems, 1998, Volume: 28, Issue:11

    Topics: Anticonvulsants; Chlorzoxazone; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Humans; In Vitro Techniques; Inactivation, Metabolic; Isoenzymes; Liver; Methylation; Microsomes, Liver; Trimethadione

1998