Compounds > chlorzoxazone

chlorzoxazone and trichloroethylene

chlorzoxazone has been researched along with trichloroethylene in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's2 (33.33)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Garrett, CM; Lipscomb, JC; Snawder, JE1
Cummings, BS; Lash, LH; Parker, JC1
Huang, P; Hueni, SE; Lash, LH; Parker, JC; Putt, DA1

Other Studies

6 other study(ies) available for chlorzoxazone and trichloroethylene

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Cytochrome P450-dependent metabolism of trichloroethylene: interindividual differences in humans.
    Toxicology and applied pharmacology, 1997, Volume: 142, Issue:2

    Topics: Analysis of Variance; Biotransformation; Blotting, Western; Chlorzoxazone; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Electrophoresis; Female; Humans; Male; Microsomes, Liver; Risk Assessment; Solvents; Species Specificity; Trichloroethylene

1997
Cytochrome p450-dependent metabolism of trichloroethylene in rat kidney.
    Toxicological sciences : an official journal of the Society of Toxicology, 2001, Volume: 60, Issue:1

    Topics: Animals; Blotting, Western; Chloral Hydrate; Chlorzoxazone; Clofibrate; Cytochrome P-450 Enzyme System; Enzyme Induction; In Vitro Techniques; Kidney Tubules, Distal; Kidney Tubules, Proximal; Male; Microsomes, Liver; Proadifen; Pyridines; Rats; Rats, Inbred F344; Trichloroethylene

2001
Modulation of hepatic and renal metabolism and toxicity of trichloroethylene and perchloroethylene by alterations in status of cytochrome P450 and glutathione.
    Toxicology, 2007, Jun-03, Volume: 235, Issue:1-2

    Topics: Animals; Biotransformation; Carcinogens, Environmental; Cell Survival; Chlorzoxazone; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ditiocarb; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Glutathione; Hepatocytes; In Vitro Techniques; Kidney Cortex; Kinetics; Male; Metyrapone; Microsomes; Proadifen; Pyridines; Rats; Rats, Inbred F344; Tetrachloroethylene; Trichloroethylene

2007