chlorzoxazone has been researched along with phenobarbital in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (30.77) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 4 (30.77) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bennetts, WW; Gardocki, JF; Marakowski, J; Molinari, AJ; Plampin, JN; Price, BE; Rasmussen, CR; Reynolds, BE; Schwartz, N; Twardzik, BL | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Gray, WD; Osterberg, AC; Scuto, TJ | 1 |
| Maki, Y | 1 |
| Bender, AD; Greene, L; Macko, E; Tedeschi, RE; Wilfon, G | 1 |
| Chen, L; Yang, CS | 1 |
| Catania, JR; McGarrigle, BP; Olson, JR; Rittenhouse-Olson, K | 1 |
| Joshi, M; Lee, AM; Tyndale, RF; Yue, J | 1 |
1 review(s) available for chlorzoxazone and phenobarbital
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
12 other study(ies) available for chlorzoxazone and phenobarbital
| Article | Year |
|---|---|
2-Pyrrolidinylideneureas, a new class of central nervous system agents.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Central Nervous System Agents; Dose-Response Relationship, Drug; Hypnotics and Sedatives; Lethal Dose 50; Mice; Muscle Relaxants, Central; Pyrrolidines; Rats; Structure-Activity Relationship; Thiourea; Urea | 1978 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Measurement of the analgesic efficacy and potency of pentazocine by the D'Amour and Smith method.
Topics: Analgesics; Animals; Chlorpromazine; Chlorzoxazone; Cyclazocine; Hot Temperature; Male; Meperidine; Methods; Methotrimeprazine; Morphinans; Morphine; Nalorphine; Narcotic Antagonists; Pentazocine; Phenobarbital; Rats; Reaction Time | 1970 |
Mephenoxalone hydroxylation in rat liver microsomes.
Topics: Aminopyrine; Aniline Compounds; Animals; Benzopyrenes; Catechols; Chlorzoxazone; Liver; Microsomes; Oxazoles; Phenobarbital; Rats; Tranquilizing Agents | 1968 |
Pharmacological properties of the isopropyl ester of o-sulfamoyl-benzoic acid.
Topics: Animals; Behavior, Animal; Benzoates; Carbamates; Carisoprodol; Chlordiazepoxide; Chlormezanone; Chlorzoxazone; Dogs; Drug Antagonism; Electroshock; Male; Mephenesin; Meprobamate; Methocarbamol; Mice; Muscles; Pentobarbital; Phenethylamines; Phenobarbital; Phenytoin; Rats; Reflex; Seizures; Sleep; Strychnine; Trimethadione; Zoxazolamine | 1967 |
Effects of cytochrome P450 2E1 modulators on the pharmacokinetics of chlorzoxazone and 6-hydroxychlorzoxazone in rats.
Topics: Allyl Compounds; Animals; Chlorzoxazone; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Enzyme Inhibitors; Ethanol; Hydroxylation; Male; Muscle Relaxants, Central; Oxidoreductases, N-Demethylating; Phenobarbital; Rats; Rats, Sprague-Dawley; Sulfides | 1996 |
Induction of CYP2B and CYP2E1 in precision-cut rat liver slices cultured in defined medium.
Topics: Animals; Blotting, Western; Cell Survival; Chlorzoxazone; Culture Media; Culture Media, Serum-Free; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Enzyme Induction; Hydroxylation; Isoenzymes; Isoniazid; Liver; Male; Microsomes, Liver; Organ Culture Techniques; Phenobarbital; Potassium; Rats; Rats, Sprague-Dawley | 2007 |
Phenobarbital induces monkey brain CYP2E1 protein but not hepatic CYP2E1, in vitro or in vivo chlorzoxazone metabolism.
Topics: Administration, Oral; Animals; Area Under Curve; Blotting, Western; Brain; Chlorocebus aethiops; Chlorzoxazone; Cytochrome P-450 CYP2E1; Hypnotics and Sedatives; Immunohistochemistry; Liver; Phenobarbital | 2006 |