chlorzoxazone has been researched along with nitrophenols in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (36.84) | 18.2507 |
| 2000's | 9 (47.37) | 29.6817 |
| 2010's | 2 (10.53) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Barrenscheen, M; Eisenbrand, G; Eliasson, E; Gonzalez, F; Greim, H; Ingelman-Sundberg, M; Janzowski, C; Landsiedel, R; Perchermeier, M; Schmalix, WA | 1 |
| Dekant, W; Speerschneider, P | 1 |
| Horbach, GJ; Maas, RF; van Miert, AS; Witkamp, RF; Zweers-Zeilmaker, WM | 1 |
| Amet, Y; Berthou, F; Dréano, Y; Goasduff, T; Zerilli, A | 1 |
| Amato, G; Gervasi, PG; Longo, V; Mazzaccaro, A | 1 |
| Kitteringham, NR; Park, BK; Pirmohamed, M; Powell, H; Smith, DA | 1 |
| Binet, S; Cossec, B; Lambert, AM; Morel, G | 1 |
| Chiba, K; Kobayashi, K; Shimada, N; Urashima, K | 1 |
| Harris, D; Park, JY | 1 |
| Ando, M; Hanioka, N; Jinno, H; Makino, Y; Matsushima, E; Miyata, Y; Ohno, A; Tanaka-Kagawa, T; Yoda, R | 1 |
| Forkert, PG; Ghanayem, BI; Millen, B; Reilly, CA; Sharma, A; Simmonds, AC; Yost, GS | 1 |
| Ekman, S; Fransson-Steen, R; Hagbjörk, AL; Löfgren, S; Terelius, Y | 1 |
| Fairhead, M; Giannini, S; Gilardi, G; Gillam, EM | 1 |
| Friis, C; Skaanild, MT | 1 |
| Alcorn, J; Allouh, MZ; Elbarbry, FA; McNamara, PJ | 1 |
| Ahn, T; Chae, HJ; Chae, SW; Cho, EY; Kim, HR; Lee, GH | 1 |
| Ahn, T; Jung, HC; Kim, D; Kim, DH; Pan, JG; Park, SH; Yun, CH | 1 |
| Chu, Y; Hebner, M; Jones, JP; Joswig-Jones, CA; Koop, DR | 1 |
| Anh Nguyen, N; Beum Park, C; Huong Ha Nguyen, T; Kang, HS; Kim, J; Le, TK; Sun, EG; Yee, SM; Yeom, SJ; Yun, CH | 1 |
19 other study(ies) available for chlorzoxazone and nitrophenols
| Article | Year |
|---|---|
Stable expression of human cytochrome P450 2E1 in V79 Chinese hamster cells.
Topics: Animals; Blotting, Northern; Blotting, Southern; Blotting, Western; Cell Line; Cell Survival; Chlorzoxazone; Cricetinae; Cricetulus; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Genetic Vectors; Humans; Microsomes; Mutagens; Nitrophenols; Oxidoreductases, N-Demethylating; Recombinant Proteins; Transfection | 1995 |
Renal tumorigenicity of 1,1-dichloroethene in mice: the role of male-specific expression of cytochrome P450 2E1 in the renal bioactivation of 1,1-dichloroethene.
Topics: Acetates; Administration, Inhalation; Animals; Biotransformation; Blotting, Western; Carcinogens; Chlorzoxazone; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dichloroethylenes; Female; Humans; Hydroxylation; Kidney; Kidney Neoplasms; Liver; Lung; Male; Mice; Microsomes; Nitrophenols; Oxidation-Reduction; Oxidoreductases, N-Demethylating; Rats; Sex Factors; Species Specificity; Testosterone | 1995 |
Cytochrome P4502E in vivo and in vitro in the dwarf goat: effects of enzyme induction and the applicability of chlorzoxazone as marker substrate.
Topics: Aniline Compounds; Animals; Antitubercular Agents; beta-Naphthoflavone; Biotransformation; Blotting, Western; Chlorzoxazone; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Enzyme Inhibitors; Female; Goats; Hydroxylation; In Vitro Techniques; Isoniazid; Microsomes, Liver; Nitrophenols; Oxidoreductases, N-Demethylating | 1996 |
Noninvolvement of CYP2E1 in the (omega-1)-hydroxylation of fatty acids in rat kidney microsomes.
Topics: Animals; Chlorzoxazone; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fatty Acids; Immunologic Techniques; Kidney; Male; Microsomes; Mixed Function Oxygenases; Nitrophenols; Rats; Rats, Sprague-Dawley | 1997 |
Chlorzoxazone 6-hydroxylase and p-nitrophenol hydroxylase as the most suitable activities for assaying cytochrome P450 2E1 in cynomolgus monkey liver.
Topics: Animals; Blotting, Western; Chlorzoxazone; Cytochrome P-450 CYP2E1; Female; Hydroxylation; Macaca fascicularis; Male; Microsomes, Liver; Muscle Relaxants, Central; Nitrophenols | 1998 |
Expression of cytochrome P4502E1 in human liver: assessment by mRNA, genotype and phenotype.
Topics: Adult; Aged; Chlorzoxazone; Cytochrome P-450 CYP2E1; Female; Genotype; Humans; Hydroxylation; Liver; Male; Middle Aged; Nitrophenols; Phenotype; Polymorphism, Restriction Fragment Length; RNA, Messenger; Tissue Donors | 1998 |
Evaluation of rat hepatic 2E1 activity in function of age, sex and inducers: choice of an experimental model capable of testing the hepatotoxicity of low molecular weight compounds.
Topics: Age Factors; Animals; Chlorzoxazone; Cytochrome P-450 CYP2E1; Enzyme Induction; Female; Liver; Male; Molecular Weight; Nitrophenols; Rats; Rats, Sprague-Dawley; Sex Factors | 1999 |
Substrate specificity for rat cytochrome P450 (CYP) isoforms: screening with cDNA-expressed systems of the rat.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Baculoviridae; Cells, Cultured; Chlorzoxazone; Coumarins; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dextromethorphan; Diclofenac; DNA, Complementary; Ethanolamines; Gene Expression; Humans; Insecta; Isoenzymes; Mephenytoin; Midazolam; Nitrophenols; Pharmaceutical Preparations; Phenacetin; Rats; Substrate Specificity; Testosterone; Tumor Cells, Cultured | 2002 |
Construction and assessment of models of CYP2E1: predictions of metabolism from docking, molecular dynamics, and density functional theoretical calculations.
Topics: Amino Acid Sequence; Animals; Bacteria; Binding Sites; Chlorzoxazone; Cytochrome P-450 CYP2E1; Dimethylnitrosamine; Ligands; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Molecular Structure; Nitrophenols; Quantum Theory; Rabbits; Structure-Activity Relationship; Substrate Specificity; Thermodynamics | 2003 |
Functional characterization of three human cytochrome p450 2E1 variants with amino acid substitutions.
Topics: Amino Acid Substitution; Animals; Chlorzoxazone; COS Cells; Cytochrome P-450 CYP2E1; DNA Primers; DNA, Complementary; Humans; Kinetics; Nitrophenols; Plasmids; RNA, Messenger | 2003 |
Bioactivation of 1,1-dichloroethylene by CYP2E1 and CYP2F2 in murine lung.
Topics: Animals; Blotting, Western; Chlorzoxazone; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Cytosol; Dichloroethylenes; Female; Hydroxylation; Lung; Mice; Nitrophenols | 2004 |
Metabolism of human cytochrome P450 marker substrates in mouse: a strain and gender comparison.
Topics: Amiodarone; Animals; Aryl Hydrocarbon Hydroxylases; Blotting, Western; Chlorzoxazone; Coumarins; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2B6; Cytochrome P-450 Enzyme System; Dextromethorphan; Diclofenac; DNA, Complementary; Ethanolamines; Female; Humans; Kinetics; Lauric Acids; Male; Mephenytoin; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Microsomes, Liver; Mixed Function Oxygenases; NADP; Nitrophenols; Oxidoreductases, N-Demethylating; Oxygen; Paclitaxel; Phenacetin; Rats; Sex Factors; Species Specificity; Substrate Specificity; Testosterone | 2004 |
Functional characterisation of an engineered multidomain human P450 2E1 by molecular Lego.
Topics: Biotransformation; Chlorzoxazone; Cytochrome P-450 CYP2E1; Cytochromes b5; Humans; Hydroxylation; Mixed Function Oxygenases; NADP; Nitrophenols; Oxygen; Protein Conformation; Protein Structure, Tertiary; Recombinant Fusion Proteins | 2005 |
Is bupropion a more specific substrate for porcine CYP2E than chlorzoxazone and p-nitrophenol?
Topics: Animals; Bupropion; Chlorzoxazone; Cytochrome P-450 CYP2E1; Female; Hydroxylation; Male; Microsomes, Liver; Nitrophenols; Substrate Specificity; Swine; Swine, Miniature | 2007 |
Evaluation of the assumptions of an ontogeny model of rat hepatic cytochrome P450 activity.
Topics: Age Factors; Aging; Animals; Body Weight; Chlorzoxazone; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Cytochromes; Dealkylation; Hydroxylation; Isoenzymes; Kinetics; Liver; Male; Microsomes, Liver; Models, Biological; Nitrophenols; Organ Size; Oxazines; Phenacetin; Proteins; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Risk Assessment; Substrate Specificity | 2007 |
Bax inhibitor 1 regulates ER-stress-induced ROS accumulation through the regulation of cytochrome P450 2E1.
Topics: Apoptosis Regulatory Proteins; Cell Death; Cell Line, Tumor; Chlorzoxazone; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Endoplasmic Reticulum; Enzyme Inhibitors; Humans; Hydroxylation; Kinetics; Lipid Peroxidation; Membrane Proteins; NADPH-Ferrihemoprotein Reductase; Nitrophenols; Oxidative Stress; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Substrate Specificity; Transfection | 2009 |
Engineering bacterial cytochrome P450 (P450) BM3 into a prototype with human P450 enzyme activity using indigo formation.
Topics: Amino Acid Substitution; Bacterial Proteins; Biocatalysis; Carbon; Chlorzoxazone; Coumarins; Cytochrome P-450 Enzyme System; Enzyme Stability; Escherichia coli; Heme; Humans; Indigo Carmine; Indoles; Kinetics; Molecular Dynamics Simulation; NADPH-Ferrihemoprotein Reductase; Nitrophenols; Oxazines; Oxidation-Reduction; Phenacetin; Protein Engineering; Recombinant Proteins; Transformation, Genetic; Umbelliferones | 2010 |
The effects of nitrogen-heme-iron coordination on substrate affinities for cytochrome P450 2E1.
Topics: Chlorzoxazone; Cytochrome P-450 CYP2E1; Heme; Iron; Kinetics; Nitrogen; Nitrophenols; Protein Binding; Quantum Theory; Solvents; Substrate Specificity | 2011 |
Solar-Powered Whole-Cell P450 Catalytic Platform for C-Hydroxylation Reactions.
Topics: Catalysis; Chlorzoxazone; Cytochrome P-450 Enzyme System; Escherichia coli; Flavin Mononucleotide; Hydroxylation; Light; Nitrophenols; Oxidation-Reduction; Photosensitizing Agents; Photosynthesis; Solar Energy | 2021 |