chlorzoxazone has been researched along with nicotine in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Leszkovszky, GP; Tardos, L | 1 |
| Gorosito, M; Sabelli, HC | 1 |
| Howard, LA; Micu, AL; Sellers, EM; Tyndale, RF | 1 |
| Lee, AM; Tyndale, RF; Yue, J | 1 |
| Benowitz, NL; Dempsey, D; Hukkanen, J; Jacob Iii, P; Peng, M | 1 |
1 trial(s) available for chlorzoxazone and nicotine
| Article | Year |
|---|---|
Effects of nicotine on cytochrome P450 2A6 and 2E1 activities.
Topics: Adult; Aged; Aryl Hydrocarbon Hydroxylases; Chlorzoxazone; Cotinine; Cross-Over Studies; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Humans; Male; Metabolic Clearance Rate; Middle Aged; Muscle Relaxants, Central; Nicotine; Nicotinic Agonists; Single-Blind Method; Smoking; Young Adult | 2010 |
9 other study(ies) available for chlorzoxazone and nicotine
| Article | Year |
|---|---|
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Pharmacology of a new centrally acting muscle relaxant (RJ-64).
Topics: Animals; Anticonvulsants; Cats; Chlorzoxazone; Interneurons; Mice; Motor Activity; Muscle Contraction; Muscle Relaxants, Central; Muscles; Nicotine; Oxadiazoles; Rats; Reflex; Spasm; Strychnine; Synaptic Transmission | 1970 |
Evidence for biogenic amine receptors in toad sciatic nerves.
Topics: Animals; Anura; Axons; Chlorpromazine; Chlorzoxazone; Cocaine; Drug Antagonism; Epinephrine; Histamine; Imipramine; Lysergic Acid Diethylamide; Membranes; Neural Conduction; Nicotine; Nicotinic Acids; Pentolinium Tartrate; Potassium Chloride; Procaine; Sciatic Nerve; Sensory Receptor Cells; Serotonin; Sodium; Time Factors | 1969 |
Low doses of nicotine and ethanol induce CYP2E1 and chlorzoxazone metabolism in rat liver.
Topics: Animals; Behavior, Animal; Blotting, Western; Central Nervous System Depressants; Chlorzoxazone; Cytochrome P-450 CYP2E1; Enzyme Induction; Ethanol; Immunohistochemistry; Liver; Male; Muscle Relaxants, Central; Nicotine; Nicotinic Agonists; Rats; Rats, Wistar; RNA, Messenger | 2001 |
In vivo and in vitro characterization of chlorzoxazone metabolism and hepatic CYP2E1 levels in African Green monkeys: induction by chronic nicotine treatment.
Topics: Animals; Chlorocebus aethiops; Chlorzoxazone; Cytochrome P-450 CYP2E1; Enzyme Induction; Liver; Male; Microsomes, Liver; Muscle Relaxants, Central; Nicotine | 2006 |