Compounds > chlorzoxazone

chlorzoxazone and nadp

chlorzoxazone has been researched along with nadp in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (37.50)18.2507
2000's3 (37.50)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Grant, SK; Green, BG; Kozarich, JW; Pacholok, SG; Wang, R1
Court, MH; Greenblatt, DJ; Shader, RI; Von Moltke, LL1
Dong, MS; Gillam, EM; Guengerich, FP; Johnson, WW; Shimada, T; Yamazaki, H1
Fernandez, M; Hashemi, E; Ioannides, C; Lewis, DF; Papagiannidou, E; Skene, DJ; Snelling, J1
Ekman, S; Fransson-Steen, R; Hagbjörk, AL; Löfgren, S; Terelius, Y1
Fairhead, M; Giannini, S; Gilardi, G; Gillam, EM1
Auchus, RJ; Peng, HM1
Blanchard, AP; Creegan, TP; Dehal, SS; Gangl, ET; Mason, AK; Perloff, ES; Singh, R; Stresser, DM1

Other Studies

8 other study(ies) available for chlorzoxazone and nadp

ArticleYear
Characterization of inducible nitric-oxide synthase by cytochrome P-450 substrates and inhibitors. Inhibition by chlorzoxazone.
    The Journal of biological chemistry, 1997, Jan-10, Volume: 272, Issue:2

    Topics: Animals; Chlorzoxazone; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Hemin; Humans; Isoenzymes; Kinetics; Muscle Relaxants, Central; NADP; Nitric Oxide Synthase; Rats

1997
Biotransformation of chlorzoxazone by hepatic microsomes from humans and ten other mammalian species.
    Biopharmaceutics & drug disposition, 1997, Volume: 18, Issue:3

    Topics: Aged; Animals; Antidotes; Biotransformation; Cats; Cattle; Chlorzoxazone; Cytochrome P-450 CYP2E1; Ditiocarb; Dogs; Enzyme Inhibitors; Female; Ferrets; Horses; Humans; In Vitro Techniques; Macaca fascicularis; Mice; Microsomes, Liver; Middle Aged; Muscle Relaxants, Central; NADP; Rabbits; Rats; Species Specificity; Swine

1997
Reconstitution of recombinant cytochrome P450 2C10(2C9) and comparison with cytochrome P450 3A4 and other forms: effects of cytochrome P450-P450 and cytochrome P450-b5 interactions.
    Archives of biochemistry and biophysics, 1997, Jun-15, Volume: 342, Issue:2

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Chlorzoxazone; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Cytochromes b5; Escherichia coli; Ethanolamines; Humans; Hydroxylation; Mixed Function Oxygenases; Mutation; NADP; Nifedipine; Oxidation-Reduction; Phospholipids; Recombinant Proteins; Testosterone; Theophylline; Tolbutamide; Warfarin

1997
Contribution of CYP1A2 in the hepatic metabolism of melatonin: studies with isolated microsomal preparations and liver slices.
    Journal of pineal research, 2001, Volume: 31, Issue:4

    Topics: Animals; Benzoflavones; Chlorzoxazone; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Enzyme Inhibitors; In Vitro Techniques; Liver; Male; Melatonin; Microsomes, Liver; Models, Molecular; NADP; Oxidation-Reduction; Rats; Rats, Wistar; Theophylline

2001
Metabolism of human cytochrome P450 marker substrates in mouse: a strain and gender comparison.
    Xenobiotica; the fate of foreign compounds in biological systems, 2004, Volume: 34, Issue:9

    Topics: Amiodarone; Animals; Aryl Hydrocarbon Hydroxylases; Blotting, Western; Chlorzoxazone; Coumarins; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2B6; Cytochrome P-450 Enzyme System; Dextromethorphan; Diclofenac; DNA, Complementary; Ethanolamines; Female; Humans; Kinetics; Lauric Acids; Male; Mephenytoin; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Microsomes, Liver; Mixed Function Oxygenases; NADP; Nitrophenols; Oxidoreductases, N-Demethylating; Oxygen; Paclitaxel; Phenacetin; Rats; Sex Factors; Species Specificity; Substrate Specificity; Testosterone

2004
Functional characterisation of an engineered multidomain human P450 2E1 by molecular Lego.
    Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2005, Volume: 10, Issue:8

    Topics: Biotransformation; Chlorzoxazone; Cytochrome P-450 CYP2E1; Cytochromes b5; Humans; Hydroxylation; Mixed Function Oxygenases; NADP; Nitrophenols; Oxygen; Protein Conformation; Protein Structure, Tertiary; Recombinant Fusion Proteins

2005
The action of cytochrome b(5) on CYP2E1 and CYP2C19 activities requires anionic residues D58 and D65.
    Biochemistry, 2013, Jan-08, Volume: 52, Issue:1

    Topics: Aryl Hydrocarbon Hydroxylases; Chlorzoxazone; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2E1; Cytochromes b5; Humans; Hydroxylation; Mephenytoin; Models, Molecular; Muscle Relaxants, Central; NADP; Oxidoreductases Acting on CH-CH Group Donors; Phospholipids; Point Mutation; Progesterone

2013
Selective Time- and NADPH-Dependent Inhibition of Human CYP2E1 by Clomethiazole.
    Drug metabolism and disposition: the biological fate of chemicals, 2016, Volume: 44, Issue:8

    Topics: Biotransformation; Chlormethiazole; Chlorzoxazone; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Hydroxylation; Hypnotics and Sedatives; Kinetics; Liver; Male; Microsomes, Liver; Models, Biological; NADP; Risk Assessment; Substrate Specificity

2016