chlorzoxazone has been researched along with ditiocarb in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (71.43) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gonzalez, FJ; Hatanaka, T; Hotta, H; Ono, S; Satoh, T; Tsutsui, M | 1 |
| Alexander, A; Berthou, F; Mapoles, J; Ménez, JF; Simon, F | 1 |
| Court, MH; Greenblatt, DJ; Shader, RI; Von Moltke, LL | 1 |
| Back, DJ; Eagling, VA; Tjia, JF | 1 |
| Crivello, J; Wall, KL | 1 |
| Huang, P; Hueni, SE; Lash, LH; Parker, JC; Putt, DA | 1 |
| Appel, KE; Bernauer, U; Gundert-Remy, U; Klaffke, HS; Palavinskas, R; Settels, E | 1 |
7 other study(ies) available for chlorzoxazone and ditiocarb
| Article | Year |
|---|---|
Chlorzoxazone is metabolized by human CYP1A2 as well as by human CYP2E1.
Topics: Benzoflavones; Chlorzoxazone; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ditiocarb; Humans; Hydroxylation; Microsomes, Liver; Oxidoreductases; Oxidoreductases, N-Demethylating; Recombinant Proteins; Substrate Specificity | 1995 |
Mammalian PC-12 cell genetically engineered for human cytochrome P450 2E1 expression.
Topics: 1-Butanol; Acetaminophen; Animals; Butanols; Chlorzoxazone; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Ditiocarb; Genetic Engineering; Humans; Hydroxylation; Microsomes; Oxidoreductases, N-Demethylating; Oxygenases; PC12 Cells; Transfection | 1993 |
Biotransformation of chlorzoxazone by hepatic microsomes from humans and ten other mammalian species.
Topics: Aged; Animals; Antidotes; Biotransformation; Cats; Cattle; Chlorzoxazone; Cytochrome P-450 CYP2E1; Ditiocarb; Dogs; Enzyme Inhibitors; Female; Ferrets; Horses; Humans; In Vitro Techniques; Macaca fascicularis; Mice; Microsomes, Liver; Middle Aged; Muscle Relaxants, Central; NADP; Rabbits; Rats; Species Specificity; Swine | 1997 |
Differential selectivity of cytochrome P450 inhibitors against probe substrates in human and rat liver microsomes.
Topics: Animals; Chlorzoxazone; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ditiocarb; Enzyme Inhibitors; Humans; Ketoconazole; Kinetics; Male; Microsomes, Liver; Phenacetin; Rats; Rats, Wistar; Substrate Specificity; Sulfaphenazole; Testosterone; Theophylline; Tolbutamide | 1998 |
Chlorzoxazone metabolism by winter flounder liver microsomes: evidence for existence of a CYP2E1-like isoform in teleosts.
Topics: Aniline Compounds; Animals; Benzoflavones; Chlorzoxazone; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Ditiocarb; Enzyme Inhibitors; Female; Flounder; Male; Microsomes, Liver; Muscle Relaxants, Central; Oxazines; Substrate Specificity; Troleandomycin; Water Pollutants, Chemical | 1998 |
Modulation of hepatic and renal metabolism and toxicity of trichloroethylene and perchloroethylene by alterations in status of cytochrome P450 and glutathione.
Topics: Animals; Biotransformation; Carcinogens, Environmental; Cell Survival; Chlorzoxazone; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ditiocarb; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Glutathione; Hepatocytes; In Vitro Techniques; Kidney Cortex; Kinetics; Male; Metyrapone; Microsomes; Proadifen; Pyridines; Rats; Rats, Inbred F344; Tetrachloroethylene; Trichloroethylene | 2007 |
Human CYP2E1 mediates the formation of glycidamide from acrylamide.
Topics: Acrylamide; Adult; Animals; Biotransformation; Callithrix; Carcinogens; Cell Line; Chlorzoxazone; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Ditiocarb; Enzyme Inhibitors; Epoxy Compounds; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydroxylation; Kinetics; Microsomes, Liver; Middle Aged; Recombinant Proteins; Risk Assessment; Species Specificity; Substrate Specificity; Transfection | 2008 |