Compounds > chlorzoxazone

chlorzoxazone and aniline

chlorzoxazone has been researched along with aniline in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (60.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bell, LC; Gillam, EM; Guengerich, FP; Nakano, M; Shimada, T; Yamazaki, H1
Horbach, GJ; Maas, RF; van Miert, AS; Witkamp, RF; Zweers-Zeilmaker, WM1
Crivello, J; Wall, KL1
Chen, J; Dong, G; He, C; Liu, Y; Peng, R; Yue, J1
Chou, KC; Li, J; Wang, JF; Wei, DQ; Yu, ZT1

Other Studies

5 other study(ies) available for chlorzoxazone and aniline

ArticleYear
Requirements for cytochrome b5 in the oxidation of 7-ethoxycoumarin, chlorzoxazone, aniline, and N-nitrosodimethylamine by recombinant cytochrome P450 2E1 and by human liver microsomes.
    Biochemical pharmacology, 1996, Jul-26, Volume: 52, Issue:2

    Topics: Aniline Compounds; Chlorzoxazone; Coumarins; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochromes b5; Dimethylnitrosamine; Humans; Kinetics; Microsomes, Liver; NADH, NADPH Oxidoreductases; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Oxidoreductases; Oxidoreductases, N-Demethylating; Recombinant Proteins

1996
Cytochrome P4502E in vivo and in vitro in the dwarf goat: effects of enzyme induction and the applicability of chlorzoxazone as marker substrate.
    Journal of veterinary pharmacology and therapeutics, 1996, Volume: 19, Issue:3

    Topics: Aniline Compounds; Animals; Antitubercular Agents; beta-Naphthoflavone; Biotransformation; Blotting, Western; Chlorzoxazone; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Enzyme Inhibitors; Female; Goats; Hydroxylation; In Vitro Techniques; Isoniazid; Microsomes, Liver; Nitrophenols; Oxidoreductases, N-Demethylating

1996
Chlorzoxazone metabolism by winter flounder liver microsomes: evidence for existence of a CYP2E1-like isoform in teleosts.
    Toxicology and applied pharmacology, 1998, Volume: 151, Issue:1

    Topics: Aniline Compounds; Animals; Benzoflavones; Chlorzoxazone; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Ditiocarb; Enzyme Inhibitors; Female; Flounder; Male; Microsomes, Liver; Muscle Relaxants, Central; Oxazines; Substrate Specificity; Troleandomycin; Water Pollutants, Chemical

1998
Protective effects of thiopronin against isoniazid-induced hepatotoxicity in rats.
    Toxicology, 2009, Oct-29, Volume: 264, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Alanine Transaminase; Aniline Compounds; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Chlorzoxazone; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Cytoprotection; Deoxyguanosine; Disease Models, Animal; DNA Adducts; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Glutathione Transferase; Hydroxylation; Isoniazid; Kinetics; Liver; Liver Diseases; Male; Oxidative Stress; Rats; Rats, Wistar; Tiopronin

2009
Molecular dynamics simulations of CYP2E1.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2012, Volume: 8, Issue:2

    Topics: Acetaminophen; Aniline Compounds; Benzene; Biocatalysis; Catalytic Domain; Chlorzoxazone; Crystallography, X-Ray; Cytochrome P-450 CYP2E1; Models, Molecular; Molecular Dynamics Simulation; Structure-Activity Relationship; Theophylline

2012