chlorthalidone and telmisartan

chlorthalidone has been researched along with telmisartan in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (12.50)29.6817
2010's6 (37.50)24.3611
2020's8 (50.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Gwon, MR; Kang, WY; Kim, BK; Kim, HJ; Lee, HW; Lee, J; Lim, MS; Ohk, B; Seong, SJ; Yang, DH; Yoon, YR1
Cho, HJ; Choi, DJ; Han, KR; Jo, SH; Kim, EJ; Kim, SJ; Park, JJ; Park, SJ; Shin, J; Shin, JH; Song, JM1
Amarasekara, S; Amarasena, N; Billot, L; de Silva, AP; de Silva, HA; Fernando, M; Guggilla, R; Jan, S; Jayawardena, J; Maulik, PK; Mendis, S; Munasinghe, J; Naik, N; Patel, A; Prabhakaran, D; Rajapakse, S; Ranasinghe, G; Rodgers, A; Salam, A; Selak, V; Senaratne, V; Stepien, S; Thom, S; Tisserra, N; Webster, R; Wijekoon, S; Wijeyasingam, S1
Anireddy, J; Dongala, T; Palakurthi, AK; Yalavarthi, RK1
Billot, L; de Silva, A; Guggilla, R; Jan, S; Maulik, PK; Mysore, J; Naik, N; Patel, A; Prabhakaran, D; Rodgers, A; Salam, A; Selak, V; Stepien, S; Thom, S; Wang, N; Webster, R1
Abdulwahab, S; Eissa, MS; Elsonbaty, A; Hasan, MA; Hassan, WS1
Agrawal, S; Anand, J; Bachani, D; Doshi, M; Gaikwad, VB; Halder, SK; Kinholkar, B; Kumar, DA; Kumbhar, A; Mathur, R; Mehta, S; Sarkar, G; Sharma, A1
Patel, A; Prajapati, P; Shah, S1
Ahn, JC; Cho, EJ; Han, SH; Kang, SM; Kim, KH; Kim, KI; Kim, SY; Kim, W; Kim, YJ; Park, CG; Park, SJ; Park, SM; Shin, J; Shin, JH; Sohn, IS; Sung, JH; Sung, KC1
Cazabon, D; Hering, D; Krishna, A; Moran, AE; Pathni, AK; Sahoo, SK; Sharma, B1
Ahn, Y; Cha, KS; Chang, K; Cho, EJ; Choi, DJ; Choi, SY; Doh, JH; Hong, SJ; Hong, SP; Hwang, JY; Hyon, MS; Ihm, SH; Kang, WC; Kim, HS; Kim, MH; Kim, SH; Kim, WS; Kim, YH; Kwon, K; Lee, JH; Lee, N; Lim, SW; Rhee, MY; Shin, J; Son, JW; Yoo, BS1

Reviews

1 review(s) available for chlorthalidone and telmisartan

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

6 trial(s) available for chlorthalidone and telmisartan

ArticleYear
S-amlodipine plus chlorthalidone vs. S-amlodipine plus telmisartan in hypertensive patients unresponsive to amlodipine monotherapy: study protocol for a randomized controlled trial.
    Trials, 2018, Jun-20, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Chlorthalidone; Clinical Trials, Phase IV as Topic; Diuretics; Double-Blind Method; Drug Combinations; Drug Resistance; Equivalence Trials as Topic; Female; Humans; Hypertension; Male; Middle Aged; Multicenter Studies as Topic; Prospective Studies; Republic of Korea; Telmisartan; Time Factors; Treatment Outcome; Young Adult

2018
Fixed Low-Dose Triple Combination Antihypertensive Medication vs Usual Care for Blood Pressure Control in Patients With Mild to Moderate Hypertension in Sri Lanka: A Randomized Clinical Trial.
    JAMA, 2018, 08-14, Volume: 320, Issue:6

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Chlorthalidone; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Hypertension; Male; Medication Adherence; Middle Aged; Potassium; Sri Lanka; Telmisartan

2018
Association of Low-Dose Triple Combination Therapy With Therapeutic Inertia and Prescribing Patterns in Patients With Hypertension: A Secondary Analysis of the TRIUMPH Trial.
    JAMA cardiology, 2020, 11-01, Volume: 5, Issue:11

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Dose-Response Relationship, Drug; Drug Prescriptions; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Retrospective Studies; Telmisartan; Treatment Outcome

2020
Fixed-dose Combination of Metoprolol, Telmisartan, and Chlorthalidone for Essential Hypertension in Adults with Stable Coronary Artery Disease: Phase III Study.
    Advances in therapy, 2022, Volume: 39, Issue:2

    Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Coronary Artery Disease; Drug Therapy, Combination; Essential Hypertension; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Metoprolol; Telmisartan; Tetrazoles

2022
Efficacy and safety of low-dose antihypertensive combination of amlodipine, telmisartan, and chlorthalidone: A randomized, double-blind, parallel, phase II trial.
    Journal of clinical hypertension (Greenwich, Conn.), 2022, Volume: 24, Issue:10

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Essential Hypertension; Humans; Hypertension; Telmisartan; Treatment Outcome

2022
Efficacy and safety of standard dose triple combination of telmisartan 80 mg/amlodipine 5 mg/chlorthalidone 25 mg in primary hypertension: A randomized, double-blind, active-controlled, multicenter phase 3 trial.
    Journal of clinical hypertension (Greenwich, Conn.), 2023, Volume: 25, Issue:9

    Topics: Aged; Amlodipine; Chlorthalidone; Essential Hypertension; Female; Humans; Hypertension; Leukemia, Myeloid, Acute; Male; Middle Aged; Telmisartan

2023

Other Studies

9 other study(ies) available for chlorthalidone and telmisartan

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Evaluation of a Pharmacokinetic Interaction between Telmisartan and Chlorthalidone in Healthy Male Adult Subjects.
    Clinical drug investigation, 2016, Volume: 36, Issue:8

    Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Area Under Curve; Benzimidazoles; Benzoates; Chlorthalidone; Diuretics; Drug Interactions; Healthy Volunteers; Humans; Male; Middle Aged; Telmisartan; Young Adult

2016
QbD-based development of an extraction procedure for simultaneous quantification of telmisartan, amlodipine besylate and chlorthalidone in combination complex matrix formulation.
    Biomedical chromatography : BMC, 2020, Volume: 34, Issue:2

    Topics: Amlodipine; Chlorthalidone; Chromatography, High Pressure Liquid; Drug Combinations; Limit of Detection; Linear Models; Reproducibility of Results; Research Design; Tablets; Telmisartan

2020
Synchronous Spectrofluorimetry Coupled with Third-Order Derivative Signal Processing for the Simultaneous Quantitation of Telmisartan and Chlorthalidone Drug Combination in Human Plasma.
    Journal of fluorescence, 2021, Volume: 31, Issue:1

    Topics: Blood Chemical Analysis; Chlorthalidone; Drug Combinations; Humans; Limit of Detection; Spectrometry, Fluorescence; Telmisartan

2021
Simultaneous Estimation of Telmisartan, Chlorthalidone, Amlodipine Besylate and Atorvastatin by RP-HPLC Method for Synchronous Assay of Multiple FDC Products Using Analytical FMCEA-Based AQbD Approach.
    Journal of chromatographic science, 2023, Feb-03, Volume: 61, Issue:2

    Topics: Amlodipine; Atorvastatin; Chlorthalidone; Chromatography, High Pressure Liquid; Telmisartan

2023
Financial implications of protocol-based hypertension treatment: an insight into medication costs in public and private health sectors in India.
    Journal of human hypertension, 2023, Volume: 37, Issue:9

    Topics: Amlodipine; Chlorthalidone; Humans; Hypertension; India; Private Sector; Telmisartan

2023