chlorthalidone has been researched along with tak 491 in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 22 (88.00) | 24.3611 |
| 2020's | 3 (12.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bakris, GL; Cushman, WC; Huang, P; Kupfer, S; Roberts, A; Sica, D; Weber, MA; White, WB | 1 |
| Bakris, GL; Cushman, WC; Kupfer, S; Lloyd, E; Roberts, A; Sica, D; Weber, MA; White, WB | 2 |
| Bakris, GL; Cushman, WC; Handley, A; Kupfer, S; Sica, D; Song, E; Weber, MA; White, WB | 1 |
| Anderson, KV; Pierini, D | 1 |
| Baker, WL; Nigro, SC; White, WB | 1 |
| Ebeid, WM; El-Bagary, RI; El-Zaher, AA; Elkady, EF; Patonay, G | 1 |
| Barger, B; Handley, A; Kipnes, MS; Lloyd, E; Roberts, A | 1 |
| Kupfer, S; Tsai, MC; Vakilynejad, M; Wu, J | 1 |
| Barger, B; Handley, A; Lloyd, E; Roberts, A | 1 |
| Dudkowski, C; Karim, A; Munsaka, M | 1 |
| Dargad, RR; Kukrety, S; Parekh, JD | 1 |
| Bhateria, M; Bhatta, RS; Hanif, K; Jain, M; Kumar Puttrevu, S; Ramakrishna, R | 1 |
| Barger, B; Cushman, WC; Handley, A; Lloyd, E; Neutel, JM | 1 |
| Thomopoulos, C | 1 |
| Kobalava, ZD; Kulakov, VV; Villevalde, SV | 1 |
| van der Merwe, WM | 1 |
| Bakris, GL; Hisada, M; Juhasz, A; Kupfer, S; Lloyd, E; Oparil, S; Zhao, L | 1 |
| Bakris, GL; Cushman, WC; Ferdinand, KC; Lloyd, E; Weber, MA; White, WB; Wu, J | 1 |
| Agabiti-Rosei, E; Caulfield, MJ; Collier, DJ; Hisada, M; Juhasz, A; Kupfer, S; Lloyd, E; Zhao, L | 1 |
| Hussein, LA; Ibrahim, MA; Magdy, NN | 1 |
| Amer, SM; Gad, MA; Hassan, SA; Zaazaa, HE | 1 |
| Kim, GH; Kwon, A | 1 |
| Antonopoulos, AS; Katsi, V; Michalakeas, C; Soulaidopoulos, S; Tousoulis, D; Tsioufis, K; Vlachopoulos, C | 1 |
4 review(s) available for chlorthalidone and tak 491
| Article | Year |
|---|---|
Edarbyclor: an ARB/chlorthalidone combination for hypertension.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Chlorthalidone; Clinical Trials as Topic; Drug Combinations; Humans; Hypertension; Oxadiazoles | 2012 |
Efficacy of azilsartan medoxomil with chlorthalidone in hypertension.
Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Blood Pressure; Chlorthalidone; Diuretics; Drug Therapy, Combination; Humans; Hypertension; Oxadiazoles; Randomized Controlled Trials as Topic; Treatment Outcome | 2014 |
Single-pill Combination Therapy of Azilsartan Medoxomil/Chlorthalidone for Treatment of Hypertension: A Systematic Review.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Chlorthalidone; Drug Combinations; Humans; Hypertension; Oxadiazoles | 2020 |
Evaluating the Safety and Tolerability of Azilsartan Medoxomil Alone or in Combination With Chlorthalidone in the Management of Hypertension: A Systematic Review.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Blood Pressure; Chlorthalidone; Drug Therapy, Combination; Humans; Hypertension; Oxadiazoles; Treatment Outcome; Uric Acid | 2021 |
12 trial(s) available for chlorthalidone and tak 491
| Article | Year |
|---|---|
Blood pressure-lowering efficacy of the fixed-dose combination of azilsartan medoxomil and chlorthalidone: a factorial study.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Black People; Blood Pressure; Chlorthalidone; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Oxadiazoles; Treatment Outcome; White People | 2012 |
Azilsartan medoxomil plus chlorthalidone reduces blood pressure more effectively than olmesartan plus hydrochlorothiazide in stage 2 systolic hypertension.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Black People; Blood Pressure; Chlorthalidone; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Oxadiazoles; Severity of Illness Index; Tetrazoles; Treatment Outcome; White People | 2012 |
Antihypertensive efficacy of hydrochlorothiazide vs chlorthalidone combined with azilsartan medoxomil.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Blood Pressure Monitoring, Ambulatory; Chlorthalidone; Creatinine; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Oxadiazoles; Potassium; Systole | 2012 |
Safety, tolerability, and efficacy of azilsartan medoxomil with or without chlorthalidone during and after 8 months of treatment for hypertension.
Topics: Adult; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Blood Pressure; Chlorthalidone; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Drug Tolerance; Female; Follow-Up Studies; Humans; Hypertension; Longitudinal Studies; Male; Mass Screening; Middle Aged; Oxadiazoles; Treatment Outcome | 2015 |
Population Pharmacokinetics and Exposure-Response of a Fixed-Dose Combination of Azilsartan Medoxomil and Chlorthalidone in Patients With Stage 2 Hypertension.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Chlorthalidone; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Oxadiazoles; Treatment Outcome | 2016 |
Safety and tolerability of azilsartan medoxomil in subjects with essential hypertension: a one-year, phase 3, open-label study.
Topics: Adult; Aged; Benzimidazoles; Chlorthalidone; Cohort Studies; Dizziness; Drug Therapy, Combination; Essential Hypertension; Fatigue; Female; Headache; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Oxadiazoles; Sodium Chloride Symporter Inhibitors; Treatment Outcome | 2016 |
Effects of Food Intake on the Pharmacokinetics of Azilsartan Medoxomil and Chlorthalidone Alone and in Fixed-Dose Combination in Healthy Adults.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Chlorthalidone; Cohort Studies; Dietary Fats; Drug Combinations; Fasting; Female; Food-Drug Interactions; Humans; Male; Oxadiazoles; Tablets; Young Adult | 2016 |
Comparison of long-term safety of fixed-dose combinations azilsartan medoxomil/chlorthalidone vs olmesartan medoxomil/hydrochlorothiazide.
Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Blood Pressure; Chlorthalidone; Diuretics; Dose-Response Relationship, Drug; Drug Therapy, Combination; Essential Hypertension; Female; Humans; Hydrochlorothiazide; Male; Middle Aged; Olmesartan Medoxomil; Oxadiazoles; Treatment Outcome | 2017 |
A randomized titrate-to-target study comparing fixed-dose combinations of azilsartan medoxomil and chlorthalidone with olmesartan and hydrochlorothiazide in stage-2 systolic hypertension.
Topics: Aged; Antihypertensive Agents; Benzimidazoles; Blood Pressure; Chlorthalidone; Diuretics; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Oxadiazoles; Tetrazoles | 2018 |
Long-term efficacy and tolerability of azilsartan medoxomil/chlorthalidone vs olmesartan medoxomil/hydrochlorothiazide in chronic kidney disease.
Topics: Aged; Benzimidazoles; Chlorthalidone; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Olmesartan Medoxomil; Oxadiazoles; Renal Insufficiency, Chronic; Treatment Outcome | 2018 |
Comparison of Effectiveness of Azilsartan Medoxomil and Olmesartan in Blacks Versus Whites With Systemic Hypertension.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Black or African American; Chlorthalidone; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Oxadiazoles; Tetrazoles; United States; White People | 2018 |
Efficacy and safety of azilsartan medoxomil/chlortalidone fixed-dose combination in hypertensive patients uncontrolled on azilsartan medoxomil alone: A randomized trial.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Chlorthalidone; Drug Therapy, Combination; Essential Hypertension; Female; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Oxadiazoles; Sodium Chloride Symporter Inhibitors; Systole | 2018 |
9 other study(ies) available for chlorthalidone and tak 491
| Article | Year |
|---|---|
Azilsartan medoxomil/chlorthalidone: a new fixed-dose combination antihypertensive.
Topics: Antihypertensive Agents; Benzimidazoles; Chlorthalidone; Drug Combinations; Drug Interactions; Humans; Hypertension; Oxadiazoles; Randomized Controlled Trials as Topic | 2013 |
Stability-indicating RP-LC method for determination of azilsartan medoxomil and chlorthalidone in pharmaceutical dosage forms: application to degradation kinetics.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Chlorthalidone; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Drug Stability; Hydrolysis; Limit of Detection; Oxadiazoles; Oxidation-Reduction; Tablets | 2014 |
Azilsartan: Novel Angiotensin Receptor Blocker.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Blood Pressure; Chlorthalidone; Clinical Trials as Topic; Drug Combinations; Drug Interactions; Humans; Hypertension; Oxadiazoles; Treatment Outcome; United States; United States Food and Drug Administration | 2016 |
Pharmacokinetic-pharmacodynamic modeling of the antihypertensive interaction between azilsartan medoxomil and chlorthalidone in spontaneously hypertensive rats.
Topics: Administration, Oral; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Blood Pressure; Chlorthalidone; Chromatography, Liquid; Computer Simulation; Disease Models, Animal; Drug Monitoring; Drug Synergism; Drug Therapy, Combination; Hypertension; Models, Biological; Oxadiazoles; Rats, Inbred SHR; Sodium Chloride Symporter Inhibitors; Tandem Mass Spectrometry | 2017 |
Long-term safety of different antihypertensive regimens: The risk of unfair comparisons.
Topics: Antihypertensive Agents; Benzimidazoles; Chlorthalidone; Humans; Hydrochlorothiazide; Hypertension; Olmesartan Medoxomil; Oxadiazoles | 2018 |
[Antihypertensive Efficacy of Fixed Combination Azilsartan Medoxomil / Chlorthalidone in Patients With Uncontrolled Arterial Hypertension].
Topics: Antihypertensive Agents; Benzimidazoles; Blood Pressure; Chlorthalidone; Drug Therapy, Combination; Humans; Hypertension; Oxadiazoles; Tetrazoles; Treatment Outcome | 2017 |
Treatment of hypertension in CKD patients with azilsartan/chlorthalidone vs olmesartan/hydrochlorothiazide.
Topics: Antihypertensive Agents; Benzimidazoles; Chlorthalidone; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Olmesartan Medoxomil; Oxadiazoles; Renal Insufficiency, Chronic; Tetrazoles | 2018 |
Stability-Indicating RP-UPLC Method for Simultaneous Determination of Azilsartan Medoxomil and Chlorthalidone in Tablets in the Presence of Its Degradation Products.
Topics: Benzimidazoles; Chlorthalidone; Chromatography, High Pressure Liquid; Drug Stability; Linear Models; Oxadiazoles; Reproducibility of Results; Sensitivity and Specificity; Tablets | 2019 |
Strategies for stabilizing formulation and QbD assisted development of robust stability indicating method of azilsartan medoxomil/chlorthalidone.
Topics: Acetonitriles; Benzimidazoles; Chemistry, Pharmaceutical; Chlorthalidone; Chromatography, High Pressure Liquid; Drug Stability; Oxadiazoles; Tablets | 2020 |