chlorthalidone and sotalol

chlorthalidone has been researched along with sotalol in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19903 (33.33)18.7374
1990's0 (0.00)18.2507
2000's3 (33.33)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Delwiche, F; Staroukine, M; Telerman, M; Verniory, A1
Cocco, F; Dessì Fulgheri, P; Dettori, S; Fiori, C; Glorioso, N; Madeddu, P; Rappelli, A; Sanna, G1
Schoeman, HS; Sommers, DK; van Wyk, M1

Reviews

1 review(s) available for chlorthalidone and sotalol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for chlorthalidone and sotalol

ArticleYear
[Results obtained using a combination of a beta blockader (sotalol) and a diuretic in the treatment of arterial hypertension].
    Ortodontia, 1977, Volume: 32, Issue:3

    Topics: Angiotensin II; Chlorthalidone; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Humans; Hypertension; Placebos; Renin; Sotalol

1977
The effects of two combinations of a beta-blocker and a diuretic on diuresis in normal subjects.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1984, Mar-03, Volume: 65, Issue:9

    Topics: Adult; Atenolol; Chlorthalidone; Clinical Trials as Topic; Diuresis; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Male; Potassium; Sodium; Sotalol; Uric Acid; Urine

1984

Other Studies

6 other study(ies) available for chlorthalidone and sotalol

ArticleYear
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
[Role of renin profile and age in the choice of the therapeutic approach of arterial hypertension (author's transl)].
    Giornale italiano di cardiologia, 1981, Volume: 11, Issue:12

    Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Atenolol; Chlorthalidone; Diuretics; Drug Therapy, Combination; Humans; Hypertension; Metoprolol; Middle Aged; Prazosin; Renin; Sotalol; Spironolactone

1981