chlorthalidone and nicardipine

chlorthalidone has been researched along with nicardipine in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19902 (16.67)18.7374
1990's2 (16.67)18.2507
2000's5 (41.67)29.6817
2010's3 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Doman, TN; McGovern, SL; Seidler, J; Shoichet, BK1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Celentano, A; de Divitiis, O; Galderisi, M; Garofalo, M; Mureddu, GF; Tammaro, P2
Donnelly, R; Elliott, HL; Meredith, PA; Reid, JL1
Coxhead, PF; Douglas-Jones, AP1
Bagatin, J; Polić, S; Rakić, D; Rumboldt, Z1

Reviews

1 review(s) available for chlorthalidone and nicardipine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

5 trial(s) available for chlorthalidone and nicardipine

ArticleYear
Hypertension and arrhythmias: effects of slow-release nicardipine vs chlorthalidone: a double-blind crossover study.
    International journal of clinical pharmacology, therapy, and toxicology, 1990, Volume: 28, Issue:10

    Topics: Adult; Arrhythmias, Cardiac; Chlorthalidone; Delayed-Action Preparations; Double-Blind Method; Electroencephalography; Female; Humans; Hypertension; Male; Middle Aged; Nicardipine; Time Factors

1990
Effects on casual and 24-h ambulatory blood pressure of slow-release nicardipine and chlorthalidone in arterial essential hypertension: double-blind, crossover study.
    International journal of clinical pharmacology, therapy, and toxicology, 1990, Volume: 28, Issue:5

    Topics: Adult; Blood Pressure; Blood Pressure Determination; Chlorthalidone; Delayed-Action Preparations; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Monitoring, Physiologic; Nicardipine; Random Allocation; Time Factors

1990
Enalapril in essential hypertension: the comparative effects of additional placebo, nicardipine and chlorthalidone.
    British journal of clinical pharmacology, 1987, Volume: 24, Issue:6

    Topics: Acetylcholinesterase; Blood Pressure; Catecholamines; Chlorthalidone; Clinical Trials as Topic; Double-Blind Method; Drug Interactions; Enalapril; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nicardipine; Random Allocation

1987
A general practice trial of antihypertensive therapy comparing a combination of nicardipine and chlorthalidone with atenolol and chlorthalidone.
    The British journal of clinical practice, 1986, Volume: 40, Issue:3

    Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Chlorthalidone; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Middle Aged; Nicardipine; Nifedipine

1986
Effects of four antihypertensive monotherapies on cardiac mass and function in hypertensive patients with left ventricular hypertrophy: randomized prospective study.
    Croatian medical journal, 2002, Volume: 43, Issue:6

    Topics: Adult; Aged; Antihypertensive Agents; Chlorthalidone; Croatia; Echocardiography; Female; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left Ventricular; Indapamide; Male; Middle Aged; Nicardipine; Organ Size; Propranolol; Prospective Studies; Treatment Outcome; Ventricular Function, Left

2002

Other Studies

6 other study(ies) available for chlorthalidone and nicardipine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Identification and prediction of promiscuous aggregating inhibitors among known drugs.
    Journal of medicinal chemistry, 2003, Oct-09, Volume: 46, Issue:21

    Topics: Antifungal Agents; beta-Lactamase Inhibitors; Chemical Phenomena; Chemistry, Physical; Chymotrypsin; Enzyme Inhibitors; Kinetics; Light; Malate Dehydrogenase; Models, Molecular; Molecular Conformation; Scattering, Radiation; Structure-Activity Relationship

2003
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013