chlorthalidone has been researched along with losartan in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.35) | 18.2507 |
| 2000's | 7 (30.43) | 29.6817 |
| 2010's | 10 (43.48) | 24.3611 |
| 2020's | 5 (21.74) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Eerdmans, PH; Janssen, BJ; Smits, JF | 1 |
| Diener, HC | 1 |
| Davey, PG; Davies, JI; Dawson, A; Struthers, AD; Witham, MD | 1 |
| Acampora, C; Bevilacqua, N; Borghi, C; Caruso, D; Caruso, G; D'Avino, M; Esposti, DD; Romano, L | 1 |
| Sica, DA | 1 |
| Andraus, MH; Azevedo, CP; Borges, BC; Borges, NC; Moreira, RF; Moreno, RA; Salvadori, MC | 1 |
| Afiune Neto, A; Alves, JG; Berwanger, O; Bortolotto, L; Brandão, AA; Castro, I; Cesarino, EJ; Chaves, H; Coelho, EB; Consolim-Colombo, F; de Mello, RB; de Sousa, MR; Figueiredo Neto, JA; Franco, R; Fuchs, FD; Fuchs, SC; Ghizzoni, F; Gus, M; Irigoyen, MC; Jardim, PC; Mion, D; Moreira, LB; Moreno, H; Mosele, F; Mota, M; Nobre, F; Nóbrega, AC; Pereira e Silva, R; Poli-de-Figueiredo, CE; Ribeiro, AL; Scala, LC; Schlatter, R; Sobral Filho, DC; Steffens, AA; Vilela-Martin, JF | 1 |
| Handler, J | 1 |
| Diniz, R; Ferreira, FF; Reis do Carmo, W | 1 |
| Jeffers, BW; Wang, JG; Yan, P | 1 |
| Alves, JG; Berwanger, O; Bortolotto, LA; Brandão, AA; Castro, I; Cesarino, EJ; Chaves, H; de Alencastro, PR; de Mello, RB; de Sousa, MR; E Silva, RP; Filho, DC; Franco, RS; Fuchs, FC; Fuchs, FD; Fuchs, SC; Gomes, MM; Gus, M; Jardim, PC; Moreira, LB; Mosele, F; Neto, AA; Neto, JA; Nobre, F; Nóbrega, AC; Poli-de-Figueiredo, CE; Scala, LC; Schlatter, R; Steffens, AA; Vilela-Martin, JF; Whelton, PK | 1 |
| Cervinski, MA; Olson, NJ; Ornstein, DL | 1 |
| Chae, JK; Chae, SC; Chang, KY; Cho, JR; Choi, JH; Choi, YJ; Chun, KJ; Han, KR; Han, SH; Heo, JH; Hong, BK; Hong, SJ; Jeong, HS; Jeong, MH; Jung, J; Kang, HJ; Kang, SM; Kim, CH; Kim, DW; Kim, JJ; Kim, KS; Kim, SH; Kim, WS; Kim, YD; Kwan, J; Lee, BK; Lee, SK; Lee, SU; Park, CG; Park, SH; Shin, DG; Shin, JH; Won, KH | 1 |
| Bertoluci, C; Branchi, TV; Foppa, M; Fuchs, FD; Fuchs, SC; Santos, ABS | 1 |
| Abdelsalam, RA; Haddad, GM; Marghany, KA | 1 |
| Afiune Neto, A; Alves, JG; Berwanger, O; Bortolotto, LA; Brandão, AA; Castro, I; Cesarino, JE; Chaves, H; Consolim-Colombo, FM; de Sousa, MR; Figueiredo Neto, JA; Franco, RS; Fuchs, FC; Fuchs, FD; Fuchs, SC; Gomes, MM; Gus, M; Jardim, PC; Moreira, LB; Nobre, F; Nóbrega, AC; Pereira E Silva, R; Poli-de-Figueiredo, CE; Scala, LCN; Schlatter, RP; Sobral Filho, DC; Steffens, AA; Vilela-Martin, JF; Whelton, PK | 1 |
| Hong, SJ; Kim, HY; Kim, SY; Kim, W; Lim, SW; Park, S; Rhee, MY; Shin, J; Sung, KC | 1 |
| Choi, Y; Chung, JY; Jeon, I; Jung, J; Moon, SJ; Park, SI; Yu, KS | 1 |
| Cho, DK; Cho, GY; Cho, JM; Heo, JH; Hong, SJ; Jeong, MH; Jung, JA; Kim, DH; Kim, SH; Kim, SY; Kim, W; Kwon, K; Lee, HY; Lee, JB; Lim, SW; Park, K; Park, S; Pyun, WB; Rha, SW; Rhee, MY; Shin, J; Sung, KC | 1 |
2 review(s) available for chlorthalidone and losartan
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Effects of amlodipine and other classes of antihypertensive drugs on long-term blood pressure variability: evidence from randomized controlled trials.
Topics: Amlodipine; Antihypertensive Agents; Atenolol; Blood Pressure; Cardiovascular Diseases; Chlorthalidone; Enalapril; Humans; Hypertension; Lisinopril; Losartan; Randomized Controlled Trials as Topic | 2014 |
10 trial(s) available for chlorthalidone and losartan
| Article | Year |
|---|---|
Effects of losartan and chlorthalidone on blood pressure and renal vascular resistance index in non-diabetic patients with essential hypertension and normal renal function.
Topics: Adult; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Chlorthalidone; Cross-Over Studies; Data Interpretation, Statistical; Drug Administration Schedule; Echocardiography, Doppler; Female; Follow-Up Studies; Humans; Hypertension; Kidney Cortex; Kidney Function Tests; Losartan; Male; Middle Aged; Renal Circulation; Single-Blind Method; Time Factors; Treatment Outcome; Vascular Resistance | 2004 |
Simultaneous determination of losartan and hydrochlorothiazide in human plasma by LC/MS/MS with electrospray ionization and its application to pharmacokinetics.
Topics: Administration, Oral; Adult; Chlorthalidone; Chromatography, High Pressure Liquid; Cross-Over Studies; Female; Humans; Hydrochlorothiazide; Losartan; Male; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tetrazoles; Therapeutic Equivalency; Valine; Valsartan | 2009 |
A comparison between diuretics and angiotensin-receptor blocker agents in patients with stage I hypertension (PREVER-treatment trial): study protocol for a randomized double-blind controlled trial.
Topics: Adult; Aged; Amiloride; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Brazil; Chlorthalidone; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Research Design; Severity of Illness Index; Time Factors; Treatment Outcome | 2011 |
Effectiveness of chlorthalidone/amiloride versus losartan in patients with stage I hypertension: results from the PREVER-treatment randomized trial.
Topics: Adult; Aged; Amiloride; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Humans; Hypertension; Losartan; Middle Aged | 2016 |
Comparison of Fixed-dose Combinations of Amlodipine/Losartan Potassium/Chlorthalidone and Amlodipine/Losartan Potassium in Patients With Stage 2 Hypertension Inadequately Controlled With Amlodipine/Losartan Potassium: A Randomized, Double-blind, Multicent
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Double-Blind Method; Drug Combinations; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Treatment Outcome; Young Adult | 2017 |
Echocardiographic Left Ventricular Reverse Remodeling After 18 Months of Antihypertensive Treatment in Stage I Hypertension. Results From the Prever-Treatment Study.
Topics: Adult; Aged; Amiloride; Antihypertensive Agents; Atrial Function, Left; Atrial Remodeling; Blood Pressure; Chlorthalidone; Double-Blind Method; Echocardiography, Doppler; Female; Heart Ventricles; Humans; Hypertension; Losartan; Male; Middle Aged; Predictive Value of Tests; Time Factors; Treatment Outcome; Ventricular Function, Left; Ventricular Remodeling | 2018 |
Effectiveness of chlorthalidone/amiloride versus losartan in patients with stage I hypertension and diabetes mellitus: results from the PREVER-treatment randomized controlled trial.
Topics: Adult; Aged; Amiloride; Antihypertensive Agents; Blood Pressure; Brazil; Chlorthalidone; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Severity of Illness Index; Treatment Outcome | 2021 |
Low-Dose Triple Antihypertensive Combination Therapy in Patients with Hypertension: A Randomized, Double-Blind, Phase II Study.
Topics: Aged; Amlodipine; Antihypertensive Agents; Chlorthalidone; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Losartan; Male; Middle Aged | 2020 |
Pharmacokinetics of a Fixed-Dose Combination of Amlodipine/Losartan and Chlorthalidone Compared to Concurrent Administration of the Separate Components.
Topics: Amlodipine; Chlorthalidone; Cross-Over Studies; Drug Combinations; Humans; Losartan | 2022 |
Comparison of efficacy and safety between third-dose triple and third-dose dual antihypertensive combination therapies in patients with hypertension.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Double-Blind Method; Drug Therapy, Combination; Humans; Hypertension; Hypotension; Losartan; Treatment Outcome | 2023 |
11 other study(ies) available for chlorthalidone and losartan
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Mechanisms of renal vasoconstriction following furosemide in conscious rats.
Topics: Animals; Antihypertensive Agents; Biphenyl Compounds; Captopril; Chlorthalidone; Dose-Response Relationship, Drug; Drug Interactions; Furosemide; Hemodynamics; Imidazoles; Kidney; Losartan; Male; Rats; Rats, Wistar; Regional Blood Flow; Renal Artery; Tetrazoles; Vascular Resistance; Vasoconstriction | 1994 |
[Primary prevention of stroke. What helps--what does not help? The guidelines of the German Society of Neurology briefly summarized].
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Alcohol Drinking; Anticholesteremic Agents; Anticoagulants; Antihypertensive Agents; Arrhythmias, Cardiac; Aspirin; Atenolol; Atrial Fibrillation; Carotid Artery, Internal; Carotid Stenosis; Chlorthalidone; Clinical Trials as Topic; Diabetes Complications; Diuretics; Doxazosin; Female; Fibrinolytic Agents; Hormone Replacement Therapy; Humans; Hyperlipidemias; Hypertension; Hypolipidemic Agents; Life Style; Losartan; Male; Neurology; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Pravastatin; Primary Prevention; Risk Factors; Simvastatin; Smoking; Societies, Medical; Stroke | 2003 |
Hypothetical economic analysis of screening for left ventricular hypertrophy in high-risk normotensive populations.
Topics: Antihypertensive Agents; Cardiovascular Diseases; Chlorthalidone; Cost-Benefit Analysis; Echocardiography; Health Care Costs; Humans; Hypertrophy, Left Ventricular; Losartan; Mass Screening; Risk Factors; Treatment Outcome | 2004 |
Chlorthalidone - a renaissance in use?
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Chlorthalidone; Diuretics; Drug Combinations; Humans; Hypertension; Losartan | 2009 |
Managing erectile dysfunction in hypertensive patients.
Topics: Amides; Antihypertensive Agents; Benzopyrans; Chlorthalidone; Ethanolamines; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Impotence, Vasculogenic; Losartan; Male; Middle Aged; Nebivolol; Risk Factors | 2011 |
Phase quantification of antihypertensive drugs - Chlorthalidone, Hydrochlorothiazide, Losartan and combinations, Losartan/Chlorthalidone and Losartan/Hydrochlorothiazide - by the Rietveld method.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Chemistry, Pharmaceutical; Chlorthalidone; Crystallization; Diuretics; Drug Stability; Hydrochlorothiazide; Losartan; Powders; Temperature; Time Factors; X-Ray Diffraction | 2014 |
Sudden Severe Bleeding in a Patient with Hemochromatosis: Liver Failure or Something Else?
Topics: Antihypertensive Agents; Chlorthalidone; Hemochromatosis; Hemoglobins; Humans; Hypertension; Liver Failure; Losartan; Male; Medication Errors; Middle Aged; Phlebotomy; Platelet Count; Vitamin K Deficiency Bleeding | 2016 |
HPLC method transfer study for simultaneous determination of seven angiotensin II receptor blockers.
Topics: Acrylates; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Chlorthalidone; Chromatography, High Pressure Liquid; Hydrochlorothiazide; Imidazoles; Irbesartan; Losartan; Molecular Structure; Software; Tablets; Tetrazoles; Thiophenes; Valsartan | 2020 |