chlorthalidone and labetalol

chlorthalidone has been researched along with labetalol in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19909 (60.00)18.7374
1990's0 (0.00)18.2507
2000's4 (26.67)29.6817
2010's2 (13.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
De Chătel, R; Flammer, J; Reubi, F; Weidmann, P; Ziegler, WH1
Cherchi, A; Pirisi, R; Pisano, MR; Raffo, M; Sau, F; Seguro, C1
Cumetti, C; De Cristofaro, A; Montanari, C; Roja, M; Vergani, A1
Dal Negro, RW; Pomari, C; Trevisan, F; Turco, P; Zoccatelli, O1
Evsikov, EM; Kharchenko, VI; Liusov, VA; Mart'ianova, II; Shcheplikova, TM1
Avantaggiato, F; Balestrazzi, M; Chiarappa, R; De Cesaris, R; Grimaldi, A; Ranieri, G1
Evsikov, EM; Istomina, IA; Kharchenko, VI; Liusov, VA; Rifai, MA1
Baretta, G; Berto, R; Buniotto, P; Cogo, L; Lechi, A; Marini, F; Parrinello, A; Pomari, S; Tomasi, A1
Rossi, AG1

Reviews

1 review(s) available for chlorthalidone and labetalol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

3 trial(s) available for chlorthalidone and labetalol

ArticleYear
Alpha and beta adrenergic blockade with orally administered labetalol in hypertension. Studies on blood volume, plasma renin and aldosterone and catecholamine excretion.
    The American journal of cardiology, 1978, Volume: 41, Issue:3

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Blood Volume; Body Weight; Chlorthalidone; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Epinephrine; Ethanolamines; Female; Humans; Hypertension; Labetalol; Male; Middle Aged; Norepinephrine; Potassium; Pulse; Renin

1978
Respiratory effects of four adrenergic blocking agents combined with a diuretic in treating hypertension with concurrent chronic obstructive lung disease.
    International journal of clinical pharmacology research, 1986, Volume: 6, Issue:4

    Topics: Adrenergic beta-Antagonists; Airway Resistance; Atenolol; Chlorthalidone; Drug Therapy, Combination; Forced Expiratory Volume; Humans; Hypertension; Labetalol; Lung Diseases, Obstructive; Male; Maximal Midexpiratory Flow Rate; Metoprolol; Oxprenolol; Random Allocation

1986
Clinical evaluation of labetalol alone and combined with chlorthalidone in essential hypertension: a double-blind multicentre controlled study.
    European journal of clinical pharmacology, 1982, Volume: 22, Issue:4

    Topics: Adult; Blood Pressure; Chlorthalidone; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Ethanolamines; Female; Heart Rate; Humans; Hypertension; Labetalol; Male; Middle Aged

1982

Other Studies

11 other study(ies) available for chlorthalidone and labetalol

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
[Effect of labetalol and chlorthalidone on exercise tolerance in hypertensive subjects].
    Bollettino della Societa italiana di cardiologia, 1979, Volume: 24, Issue:6

    Topics: Adult; Chlorthalidone; Ethanolamines; Exercise Test; Hemodynamics; Humans; Hypertension; Labetalol; Male; Middle Aged

1979
Antihypertensive therapy with diuretics and beta-blockers at fixed dosage: comparison between the combinations labetalol plus chlorthalidone and atenolol plus chlorthalidone.
    Drugs under experimental and clinical research, 1985, Volume: 11, Issue:12

    Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Blood Pressure; Chlorthalidone; Diuretics; Drug Therapy, Combination; Exercise Test; Heart Rate; Humans; Hypertension; Labetalol; Male

1985
[Potentiation of the hypotensive effect of labetalol in hypertensive patients treated to maintain sodium balance in the body].
    Kardiologiia, 1987, Volume: 27, Issue:2

    Topics: Adult; Aged; Blood Pressure; Cardiac Output; Chlorthalidone; Combined Modality Therapy; Diet, Sodium-Restricted; Diuretics; Drug Synergism; Drug Therapy, Combination; Female; Humans; Hypertension; Labetalol; Male; Middle Aged; Vascular Resistance

1987
Changes in blood pressure and thermographic values resulting from use of a beta-blocker plus diuretic and of an alpha-beta-blocker plus diuretic.
    Drugs under experimental and clinical research, 1985, Volume: 11, Issue:10

    Topics: Adult; Atenolol; Body Temperature; Chlorthalidone; Drug Therapy, Combination; Heart Rate; Humans; Hypertension; Labetalol; Middle Aged; Thermography

1985
[Changes in water-sodium balance in patients with hypertension subjected to different types of hypotensive therapy].
    Kardiologiia, 1983, Volume: 23, Issue:4

    Topics: Adult; Aged; Aldosterone; Angiotensin I; Chlorthalidone; Extracellular Space; Female; Hemodynamics; Humans; Hypertension; Labetalol; Male; Middle Aged; Potassium; Sodium; Water-Electrolyte Balance

1983
Use of the the combination labetalol plus chlorthalidone in essential arterial hypertension therapy.
    Clinical therapeutics, 1981, Volume: 3, Issue:6

    Topics: Adult; Aged; Blood Pressure; Chlorthalidone; Drug Therapy, Combination; Ethanolamines; Female; Humans; Hypertension; Labetalol; Male; Middle Aged

1981