chlorthalidone has been researched along with guanfacine in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Blackshear, J; Lovallo, WR; Mathur, P; Parsons, OA; Wilson, MF | 1 |
| Alderman, MH; Canosa, FL; Finnerty, FA; Kessler, WB; Marlon, AM; Materson, BJ; McMillen, JI; Savran, SV | 1 |
| Black, PL; Freudenburg, JC; Hill, JA; Holmburg, CE; Keenan, RE; Reitbrock, MJ; Sullivan, MJ; Thompson, MT; Wright, DL | 1 |
1 review(s) available for chlorthalidone and guanfacine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
3 trial(s) available for chlorthalidone and guanfacine
| Article | Year |
|---|---|
Antihypertensive efficacy of guanfacine and methyldopa in patients with mild to moderate essential hypertension.
Topics: Adult; Aged; Aged, 80 and over; Blood Pressure; Chlorthalidone; Double-Blind Method; Drug Therapy, Combination; Female; Guanfacine; Humans; Hypertension; Male; Methyldopa; Middle Aged | 1991 |
A multicenter, randomized, double-blind dose-response evaluation of step-2 guanfacine versus placebo in mild to moderate hypertension.
Topics: Administration, Oral; Adult; Blood Pressure; Chlorthalidone; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Female; Guanfacine; Guanidines; Heart Rate; Humans; Hypertension; Male; Middle Aged; Phenylacetates; Random Allocation | 1986 |
Usefulness of low dose guanfacine, once a day, for 24-hour control of essential hypertension.
Topics: Administration, Oral; Adult; Blood Pressure; Chlorthalidone; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Electrocardiography; Female; Guanfacine; Guanidines; Heart Rate; Humans; Hypertension; Male; Middle Aged; Phenylacetates; Posture; Time Factors | 1986 |
4 other study(ies) available for chlorthalidone and guanfacine
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |