chlorthalidone has been researched along with doxazosin in 41 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (7.32) | 18.2507 |
| 2000's | 33 (80.49) | 29.6817 |
| 2010's | 4 (9.76) | 24.3611 |
| 2020's | 1 (2.44) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Cutler, JA; Elmer, PJ; Flack, JM; Grandits, GA; Grimm, RH; McDonald, R; Neaton, JD; Prineas, RJ; Schoenberger, JA; Stamler, J | 1 |
| Elmer, PJ; Flack, J; Grandits, A; Lewis, CE; McDonald, R | 1 |
| Elmer, PJ; Flack, JM; Grandits, GA; Grimm, RH; Lewis, CE; Liebson, PR; McDonald, RH; Prineas, RJ; Svendsen, K; Yunis, C | 1 |
| SoRelle, R | 1 |
| Messerli, FH | 1 |
| Einecke, D | 1 |
| Lasagna, L | 1 |
| Vidt, DG | 2 |
| Koval, PG; McDiarmid, T | 1 |
| Chen, BH | 1 |
| Aass, H; Andersen, GO; Osnes, JB; Skomedal, T | 1 |
| Schillaci, G; Verdecchia, P | 1 |
| Faulhaber, HD | 1 |
| Furberg, CD | 1 |
| Cutler, JA; Davis, BR; Farber, MA; Felicetta, JV; Furberg, CD; Stokes, JD; Wright, JT | 1 |
| Düsing, R | 2 |
| Wepner, U | 1 |
| Slany, J | 1 |
| Diener, HC | 1 |
| Barzilay, JI; Basile, JN; Bettencourt, J; Black, H; Ciocon, JO; Davis, BR; Ellsworth, A; Force, RW; Goff, DC; Habib, G; Margolis, KL; Wiegmann, T | 1 |
| Kuwajima, I | 1 |
| Arnett, DK; Black, H; Boerwinkle, E; Davis, BR; Eckfeldt, JH; Ford, CE; Leiendecker-Foster, C; Miller, MB | 2 |
| Colon, P; Crow, R; Cutler, JA; Davis, BR; Dunn, K; Ellsworth, A; Franklin, S; Furberg, C; Goff, D; Golden, J; Leenen, F; Mohiuddin, S; Papademetriou, V; Piller, LB; Proschan, M | 1 |
| Yusuf, S | 1 |
| Christian, R; Colon, PJ; Cushman, WC; Einhorn, PT; Ford, CE; Goff, DC; Henriquez, MA; Margolis, KL; Piller, LB; Vidt, DG; Wong, ND; Wright, JT | 1 |
| Arnett, DK; Boerwinkle, E; Davis, BR; Eckfeldt, JH; Ford, CE; Leiendecker-Foster, C; Lynch, AI | 2 |
| Baimbridge, C; Bareis, CJ; Barzilay, J; Basile, JN; Black, HR; Dart, R; Davis, BR; Einhorn, PT; Gupta, AK; Hamilton, BP; Harris-Haywood, S; Haywood, LJ; Jafri, SZ; Louis, GT; Pressel, S; Scott, CL; Simmons, DL; Stanford, C; Whelton, PK; Wright, JT | 1 |
| Coifman, RR; Coppi, AC; Davis, BR; Dhruva, SS; Furberg, CD; Huang, C; Krumholz, HM; Li, SX; Lin, H; Pressel, SL; Spatz, ES; Warner, F; Xu, X | 1 |
| Davis, BR; Johnson, K; Oparil, S; Tereshchenko, LG | 1 |
| Kienberger, G; Mann, E; Mansbart, F; Sönnichsen, A | 1 |
3 review(s) available for chlorthalidone and doxazosin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[ALLHAT trial--antithesis to the overuse of vasodilating antihypertensive drugs].
Topics: Adrenergic alpha-Antagonists; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzothiadiazines; Calcium Channel Blockers; Chlorthalidone; Coronary Disease; Diuretics; Double-Blind Method; Doxazosin; Humans; Hypertension; Lisinopril; Male; Randomized Controlled Trials as Topic; Sodium Chloride Symporter Inhibitors; Stroke | 2004 |
Efficacy and safety of adrenergic alpha-1 receptor antagonists in older adults: a systematic review and meta-analysis supporting the development of recommendations to reduce potentially inappropriate prescribing.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Aged; Antihypertensive Agents; Chlorthalidone; Doxazosin; Humans; Hypertension; Inappropriate Prescribing; Lower Urinary Tract Symptoms; Male; Prostatic Hyperplasia; Quality of Life | 2022 |
19 trial(s) available for chlorthalidone and doxazosin
| Article | Year |
|---|---|
Treatment of Mild Hypertension Study. Final results. Treatment of Mild Hypertension Study Research Group.
Topics: Acebutolol; Aged; Amlodipine; Antihypertensive Agents; Chlorthalidone; Diastole; Double-Blind Method; Doxazosin; Echocardiography; Electrocardiography; Enalapril; Exercise; Female; Follow-Up Studies; Health Behavior; Humans; Hypertension; Long-Term Care; Male; Middle Aged; Treatment Outcome | 1993 |
Efficacy and tolerance of antihypertensive treatment in men and women with stage 1 diastolic hypertension. Results of the Treatment of Mild Hypertension Study.
Topics: Acebutolol; Aged; Amlodipine; Antihypertensive Agents; Chlorthalidone; Doxazosin; Enalapril; Female; Humans; Hygiene; Hypertension; Life Style; Male; Middle Aged; Nutritional Physiological Phenomena; Patient Education as Topic; Severity of Illness Index; Treatment Outcome | 1996 |
Long-term effects on sexual function of five antihypertensive drugs and nutritional hygienic treatment in hypertensive men and women. Treatment of Mild Hypertension Study (TOMHS)
Topics: Acebutolol; Aged; Amlodipine; Antihypertensive Agents; Chlorthalidone; Double-Blind Method; Doxazosin; Enalapril; Female; Humans; Hypertension; Libido; Male; Middle Aged; Orgasm; Penile Erection; Sexual Dysfunction, Physiological | 1997 |
National Heart, Lung, and Blood Institute halts part of antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT)
Topics: Adrenergic alpha-Antagonists; Anticholesteremic Agents; Chlorthalidone; Diuretics; Doxazosin; Female; Heart Failure; Humans; Hypercholesterolemia; Hypertension; Male; Middle Aged; Myocardial Infarction; National Institutes of Health (U.S.); Treatment Failure; United States | 2000 |
Implications of discontinuation of doxazosin arm of ALLHAT. Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial.
Topics: Adverse Drug Reaction Reporting Systems; Anticholesteremic Agents; Antihypertensive Agents; Chlorthalidone; Doxazosin; Heart Failure; Humans; Myocardial Infarction; United States | 2000 |
[ALLHAT Study: doxazosin arm is discontinued. Alpha blocker is less effective than a diuretic].
Topics: Adrenergic alpha-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Chlorthalidone; Coronary Disease; Diuretics; Doxazosin; Humans; Hypertension; Lisinopril; Treatment Outcome | 2000 |
Major cardiovascular events in hypertensive patients randomized to doxazosin vs chlorthalidone: the antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT). ALLHAT Collaborative Research Group.
Topics: Adrenergic alpha-Antagonists; Aged; Amlodipine; Anticholesteremic Agents; Antihypertensive Agents; Cardiovascular Diseases; Chlorthalidone; Diuretics; Double-Blind Method; Doxazosin; Female; Humans; Hypertension; Lisinopril; Male; Middle Aged; Myocardial Infarction; Proportional Hazards Models; Risk; Survival Analysis | 2000 |
Relationship of antihypertensive treatment regimens and change in blood pressure to risk for heart failure in hypertensive patients randomly assigned to doxazosin or chlorthalidone: further analyses from the Antihypertensive and Lipid-Lowering treatment t
Topics: Antihypertensive Agents; Blood Pressure; Cardiac Output, Low; Chlorthalidone; Double-Blind Method; Doxazosin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Proportional Hazards Models; Risk Factors; Treatment Outcome | 2002 |
The ALLHAT Trial. Diuretics are still the preferred initial drugs for high blood pressure.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure Determination; Chlorthalidone; Diuretics; Dose-Response Relationship, Drug; Doxazosin; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Hypertension; Lisinopril; Male; Middle Aged; Patient Compliance; Probability; Risk Assessment; Severity of Illness Index; Treatment Outcome | 2003 |
Diuretic versus alpha-blocker as first-step antihypertensive therapy: final results from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).
Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Blood Pressure; Chlorthalidone; Coronary Disease; Diuretics; Double-Blind Method; Doxazosin; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Statistics as Topic; Stroke; Treatment Outcome | 2003 |
Cardiovascular outcomes using doxazosin vs. chlorthalidone for the treatment of hypertension in older adults with and without glucose disorders: a report from the ALLHAT study.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Chlorthalidone; Cohort Studies; Diabetes Complications; Diabetes Mellitus; Double-Blind Method; Doxazosin; Female; Humans; Hyperglycemia; Hypertension; Male; Risk Factors; Treatment Outcome | 2004 |
Pharmacogenetic association of the angiotensin-converting enzyme insertion/deletion polymorphism on blood pressure and cardiovascular risk in relation to antihypertensive treatment: the Genetics of Hypertension-Associated Treatment (GenHAT) study.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Chlorthalidone; Double-Blind Method; Doxazosin; Female; Follow-Up Studies; Genotype; Humans; Lisinopril; Male; Middle Aged; Peptidyl-Dipeptidase A; Pharmacogenetics; Polymorphism, Genetic; Predictive Value of Tests; Proportional Hazards Models; Risk Factors; Treatment Outcome | 2005 |
Role of diuretics in the prevention of heart failure: the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial.
Topics: Adrenergic beta-Antagonists; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Calcium Channel Blockers; Chlorthalidone; Diuretics; Double-Blind Method; Doxazosin; Drug Therapy, Combination; Female; Heart Failure; Hospitalization; Humans; Hypertension; Incidence; Lisinopril; Male; Middle Aged; Myocardial Infarction; Proportional Hazards Models; Risk; Treatment Outcome | 2006 |
Antihypertensive therapy, the alpha-adducin polymorphism, and cardiovascular disease in high-risk hypertensive persons: the Genetics of Hypertension-Associated Treatment Study.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calmodulin-Binding Proteins; Chlorthalidone; Coronary Disease; Double-Blind Method; Doxazosin; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glycine; Humans; Hypertension; Incidence; Kaplan-Meier Estimate; Lisinopril; Male; Middle Aged; Patient Selection; Polymorphism, Genetic; Proportional Hazards Models; Risk Assessment; Risk Factors; Sex Factors; Time Factors; Treatment Outcome; Tryptophan | 2007 |
Blood pressure control in Hispanics in the antihypertensive and lipid-lowering treatment to prevent heart attack trial.
Topics: Aged; Amlodipine; Antihypertensive Agents; Atenolol; Black People; Blood Pressure; Canada; Chlorthalidone; Clonidine; Double-Blind Method; Doxazosin; Female; Heart Diseases; Hispanic or Latino; Humans; Hydralazine; Hypertension; Hypolipidemic Agents; Lisinopril; Male; Middle Aged; Puerto Rico; Reserpine; Treatment Outcome; United States; United States Virgin Islands; White People | 2007 |
Clinical outcomes by race in hypertensive patients with and without the metabolic syndrome: Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).
Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Black People; Chlorthalidone; Double-Blind Method; Doxazosin; Female; Humans; Hypertension; Lisinopril; Male; Metabolic Syndrome; Middle Aged; Treatment Outcome; White People | 2008 |
Gene panels to help identify subgroups at high and low risk of coronary heart disease among those randomized to antihypertensive treatment: the GenHAT study.
Topics: Aged; Amlodipine; Antihypertensive Agents; Chlorthalidone; Coronary Disease; Doxazosin; Female; Follow-Up Studies; Genetic Association Studies; Genotype; Humans; Hypertension; Lisinopril; Male; Middle Aged; Myocardial Infarction; Polymorphism, Genetic; Proportional Hazards Models; Risk Factors; Treatment Outcome | 2012 |
Heterogeneity in Early Responses in ALLHAT (Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial).
Topics: Aged; Amlodipine; Analysis of Variance; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Chlorthalidone; Doxazosin; Drug Monitoring; Female; Humans; Hyperlipidemias; Hypertension; Hypolipidemic Agents; Lisinopril; Male; Middle Aged; Treatment Outcome | 2017 |
Prevention of Heart Failure in Hypertension-Disentangling the Role of Evolving Left Ventricular Hypertrophy and Blood Pressure Lowering: The ALLHAT Study.
Topics: Aged; Amlodipine; Antihypertensive Agents; Causality; Chlorthalidone; Doxazosin; Electrocardiography; Female; Heart Failure; Humans; Hypertension; Hypertrophy, Left Ventricular; Linear Models; Lisinopril; Logistic Models; Male; Middle Aged; Personal Protective Equipment; Proportional Hazards Models | 2019 |
19 other study(ies) available for chlorthalidone and doxazosin
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Diuretics vs alpha-blockers for treatment of hypertension: lessons from ALLHAT. Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial.
Topics: Adrenergic alpha-Antagonists; Antihypertensive Agents; Cardiovascular Diseases; Chlorthalidone; Diuretics; Doxazosin; Humans; Hypertension; Randomized Controlled Trials as Topic | 2000 |
Alpha-blockers and congestive heart failure: early termination of an arm of the ALLHAT trial.
Topics: Adrenergic alpha-Antagonists; Antihypertensive Agents; Chlorthalidone; Doxazosin; Female; Heart Failure; Humans; Male; Middle Aged; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Treatment Outcome | 2000 |
How effective is doxazosin compared with chlorthalidone in the treatment of hypertension?
Topics: Aged; Antihypertensive Agents; Cardiovascular Diseases; Chlorthalidone; Coronary Disease; Diuretics; Doxazosin; Female; Humans; Hypertension; Male; Middle Aged; Mortality; Myocardial Infarction; Random Allocation; Reproducibility of Results; Research Design; Risk Factors; Stroke | 2000 |
Hypertension and alpha-adrenergic blockers: preliminary ALLHAT results.
Topics: Adrenergic alpha-Antagonists; Aged; Canada; Chlorthalidone; Diuretics; Doxazosin; Female; Humans; Hypertension; Male; Middle Aged; Randomized Controlled Trials as Topic; Risk Factors; Treatment Outcome; United States | 2000 |
First-line antihypertensive therapy.
Topics: Antihypertensive Agents; Chlorthalidone; Doxazosin; Heart Failure; Humans; Myocardium; Randomized Controlled Trials as Topic; Receptors, Adrenergic, alpha | 2000 |
[Are all antihypertensive agents equal? Cardiovascular events in hypertensive patients randomized to treatment with doxazosin or chlorthalidone. The ALLHAT study].
Topics: Adrenergic alpha-Antagonists; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Canada; Chlorthalidone; Coronary Disease; Diuretics; Doxazosin; Humans; Hypertension; Lisinopril; Multicenter Studies as Topic; Myocardial Infarction; Randomized Controlled Trials as Topic; Risk; United States | 2000 |
[Alpha-blockers in therapy of arterial hypertension. No longer the drug of first choice].
Topics: Adrenergic alpha-Antagonists; Aged; Antihypertensive Agents; Cause of Death; Chlorthalidone; Doxazosin; Drug Therapy, Combination; Female; Heart Failure; Humans; Hypertension; Male; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic | 2001 |
Doxazosin, an inferior antihypertensive agent?
Topics: Adrenergic alpha-Antagonists; Antihypertensive Agents; Cardiovascular Diseases; Chlorthalidone; Controlled Clinical Trials as Topic; Diuretics; Doxazosin; Female; Follow-Up Studies; Humans; Hypertension; Male; Practice Guidelines as Topic; Withholding Treatment | 2002 |
Summaries for patients. Blood pressure drugs and heart failure.
Topics: Antihypertensive Agents; Blood Pressure; Cardiac Output, Low; Chlorthalidone; Double-Blind Method; Doxazosin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Risk Factors; Treatment Outcome | 2002 |
[Old or new antihypertensive drugs? Consequences from ALLHAT. Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial].
Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Chlorthalidone; Clinical Trials as Topic; Diuretics; Doxazosin; Female; Humans; Hypertension; Lisinopril; Male; Middle Aged; Myocardial Infarction; Research Design; Treatment Outcome | 2003 |
[Established blood pressure drug wins out in a comparative study. In hypertension, a diuretic first!].
Topics: Adrenergic alpha-Antagonists; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzothiadiazines; Calcium Channel Blockers; Chlorthalidone; Coronary Disease; Diuretics; Double-Blind Method; Doxazosin; Humans; Hypertension; Lisinopril; Middle Aged; Randomized Controlled Trials as Topic; Sodium Chloride Symporter Inhibitors | 2003 |
Diuretics: older, cheaper, better.
Topics: Adrenergic beta-Antagonists; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Benzothiadiazines; Blood Pressure; Calcium Channel Blockers; Chlorthalidone; Clinical Trials as Topic; Diuretics; Doxazosin; Humans; Hypertension; Lisinopril; Middle Aged; Sodium Chloride Symporter Inhibitors | 2003 |
[ALLHAT: Old Hat Hits All? On selection of the optimal antihypertensive drug].
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Cause of Death; Chlorthalidone; Dose-Response Relationship, Drug; Double-Blind Method; Doxazosin; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hypertension; Lisinopril; Long-Term Care; Male; Middle Aged; Randomized Controlled Trials as Topic; Treatment Outcome | 2003 |
[The new (old) knowledge in primary prevention of stroke. It depends on lowering of blood pressure].
Topics: Adrenergic alpha-Antagonists; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Black or African American; Calcium Channel Blockers; Chlorthalidone; Clinical Trials as Topic; Doxazosin; Follow-Up Studies; Heart Failure; Humans; Lisinopril; Middle Aged; Myocardial Infarction; Primary Prevention; Stroke; Time Factors | 2003 |
[Primary prevention of stroke. What helps--what does not help? The guidelines of the German Society of Neurology briefly summarized].
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Alcohol Drinking; Anticholesteremic Agents; Anticoagulants; Antihypertensive Agents; Arrhythmias, Cardiac; Aspirin; Atenolol; Atrial Fibrillation; Carotid Artery, Internal; Carotid Stenosis; Chlorthalidone; Clinical Trials as Topic; Diabetes Complications; Diuretics; Doxazosin; Female; Fibrinolytic Agents; Hormone Replacement Therapy; Humans; Hyperlipidemias; Hypertension; Hypolipidemic Agents; Life Style; Losartan; Male; Neurology; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Pravastatin; Primary Prevention; Risk Factors; Simvastatin; Smoking; Societies, Medical; Stroke | 2003 |
Preventing vascular events due to elevated blood pressure.
Topics: Antihypertensive Agents; Cardiovascular Diseases; Chlorthalidone; Comorbidity; Doxazosin; Drug Therapy, Combination; Heart Failure; Humans; Hypertension; Myocardial Infarction; Randomized Controlled Trials as Topic; Renal Insufficiency; Risk Factors; Stroke | 2006 |
Pharmacogenetic association of the NPPA T2238C genetic variant with cardiovascular disease outcomes in patients with hypertension.
Topics: Aged; Amlodipine; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Cardiovascular Diseases; Chlorthalidone; Diuretics; Doxazosin; Female; Genotype; Humans; Hypertension; Lisinopril; Male; Middle Aged; Pharmacogenetics; Polymorphism, Single Nucleotide | 2008 |