chlorthalidone and avapro

chlorthalidone has been researched along with avapro in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (42.86)29.6817
2010's3 (42.86)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bei, R; Bucci, M; Cipollone, F; Cuccurullo, C; Cuccurullo, F; de Cesare, D; De Luca, M; Fazia, M; Iezzi, A; Mezzetti, A; Muraro, R; Pini, B; Spigonardo, F; Ucchino, S; Zucchelli, M1
Cipollone, F; Fazia, M; Mezzetti, A1
Adams-Huet, B; Arbique, D; Auchus, RJ; Price, A; Raheja, P; Vongpatanasin, W; Wang, Z1
Abdelsalam, RA; Haddad, GM; Marghany, KA1

Reviews

1 review(s) available for chlorthalidone and avapro

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

3 trial(s) available for chlorthalidone and avapro

ArticleYear
Blockade of the angiotensin II type 1 receptor stabilizes atherosclerotic plaques in humans by inhibiting prostaglandin E2-dependent matrix metalloproteinase activity.
    Circulation, 2004, Mar-30, Volume: 109, Issue:12

    Topics: Aged; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Carotid Artery, Internal; Carotid Stenosis; Chlorthalidone; Collagen; Combined Modality Therapy; Cyclooxygenase 1; Cyclooxygenase 2; Depression, Chemical; Dinoprostone; Endarterectomy, Carotid; Enzyme Induction; Extracellular Matrix; Female; Gene Expression Regulation; Humans; Inflammation; Intramolecular Oxidoreductases; Irbesartan; Isoenzymes; Macrophages; Male; Matrix Metalloproteinase Inhibitors; Membrane Proteins; Prostaglandin-E Synthases; Prostaglandin-Endoperoxide Synthases; Protease Inhibitors; Rupture, Spontaneous; Tetrazoles

2004
[New insights on the molecular mechanisms of type-1 angiotensin II receptor blockers and their contribution to atherosclerotic plaque stabilization].
    Recenti progressi in medicina, 2004, Volume: 95, Issue:12

    Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arteriosclerosis; Biphenyl Compounds; Chlorthalidone; Cyclooxygenase 2; Endarterectomy; Humans; Intramolecular Oxidoreductases; Irbesartan; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Membrane Proteins; Metalloproteases; Prostaglandin-E Synthases; Prostaglandin-Endoperoxide Synthases; Tetrazoles

2004
Spironolactone prevents chlorthalidone-induced sympathetic activation and insulin resistance in hypertensive patients.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 60, Issue:2

    Topics: Action Potentials; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Chlorthalidone; Cross-Over Studies; Diuretics; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Insulin Resistance; Irbesartan; Male; Microelectrodes; Middle Aged; Spironolactone; Sympathetic Nervous System; Tetrazoles; Treatment Outcome

2012

Other Studies

3 other study(ies) available for chlorthalidone and avapro

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
HPLC method transfer study for simultaneous determination of seven angiotensin II receptor blockers.
    Journal of separation science, 2020, Volume: 43, Issue:8

    Topics: Acrylates; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Chlorthalidone; Chromatography, High Pressure Liquid; Hydrochlorothiazide; Imidazoles; Irbesartan; Losartan; Molecular Structure; Software; Tablets; Tetrazoles; Thiophenes; Valsartan

2020