chlorthalidone and amlodipine

chlorthalidone has been researched along with amlodipine in 117 studies

Research

Studies (117)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (2.56)18.2507
2000's55 (47.01)29.6817
2010's41 (35.04)24.3611
2020's18 (15.38)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Cutler, JA; Elmer, PJ; Flack, JM; Grandits, GA; Grimm, RH; McDonald, R; Neaton, JD; Prineas, RJ; Schoenberger, JA; Stamler, J1
Elmer, PJ; Flack, J; Grandits, A; Lewis, CE; McDonald, R1
Elmer, PJ; Flack, JM; Grandits, GA; Grimm, RH; Lewis, CE; Liebson, PR; McDonald, RH; Prineas, RJ; Svendsen, K; Yunis, C1
Schillaci, G; Verdecchia, P1
Black, H; Ghadanfar, M; Grimm, RH; Lewin, A; Rowen, R; Shi, H1
Düsing, R2
Nilsson, P1
Berglund, G; Håkansson, J; Hernborg, A; Werkö, L1
Traynor, K1
Wepner, U1
Vidt, DG1
Vetter, W1
Slany, J1
Rollins, G1
Scott, I; Stowasser, M1
Siragy, HM1
Messerli, FH; Weber, MA1
Ferdinand, KC1
Rahn, KH1
Kuwajima, I1
Leenen, FH1
Efstathiou, S; Makris, T; Manolis, A; Papavasiliou, M; Stergiou, GS1
Cushman, WC; Cutler, JA; Davis, BR; Dunn, JK; Ford, CE; Habib, GB; Haywood, LJ; Leenen, FH; Margolis, KL; Papademetriou, V; Probstfield, JL; Whelton, PK; Wright, JT1
Barzilay, J; Batuman, V; Davis, BR; Eckfeldt, JH; Farber, M; Henriquez, M; Kopyt, N; Louis, GT; Nwachuku, C; Pressel, S; Rahman, M; Saklayen, M; Stanford, C; Walworth, C; Ward, H; Whelton, PK; Wiegmann, T; Wright, JT1
Arnett, DK; Black, H; Boerwinkle, E; Davis, BR; Eckfeldt, JH; Ford, CE; Leiendecker-Foster, C; Miller, MB2
Barzilay, J; Cushman, WC; Davis, BR; Iiamathi, E; Kostis, JB; Leenen, FH; Louis, GT; Margolis, KL; Mathis, DE; Moloo, J; Nwachuku, C; Panebianco, D; Parish, DC; Pressel, S; Simmons, DL; Thadani, U; Whelton, PK1
Barzilay, J; Batuman, V; Davis, BR; Eckfeldt, JH; Farber, MA; Franklin, S; Henriquez, M; Kopyt, N; Louis, GT; Nwachuku, C; Pressel, S; Rahman, M; Saklayen, M; Stanford, C; Walworth, C; Ward, H; Whelton, PK; Wiegmann, T; Wright, JT1
Hollenberg, NK1
Colon, P; Crow, R; Cutler, JA; Davis, BR; Dunn, K; Ellsworth, A; Franklin, S; Furberg, C; Goff, D; Golden, J; Leenen, F; Mohiuddin, S; Papademetriou, V; Piller, LB; Proschan, M1
González, AB; Hunziker, P; Jung, J; Marsch, S; Mehlig, A; Scholer, A; Vogt, S; Weinmann, W1
Black, HR; Davis, BR; Ford, CE; Nwachuku, C; Oparil, S; Piller, LB; Probstfield, JL; Retta, TM1
Barzilay, JI; Basile, J; Cutler, JA; Davis, BR; Margolis, KL; Ong, ST; Pressel, SL; Sadler, LS; Summerson, J; Whelton, PK1
Scarpello, JH; Tahrani, AA; Varughese, GI1
Alberici, M; Lembo, G; Payeras, AC; Sladek, K1
Christian, R; Colon, PJ; Cushman, WC; Einhorn, PT; Ford, CE; Goff, DC; Henriquez, MA; Margolis, KL; Piller, LB; Vidt, DG; Wong, ND; Wright, JT1
Baimbridge, C; Barzilay, J; Basile, J; Black, HR; Dart, RA; Davis, B; Marginean, H; Nwachuku, C; Thadani, U; Whelton, P; Wong, ND; Wright, JT1
Arnett, DK; Boerwinkle, E; Davis, BR; Eckfeldt, JH; Ford, CE; Leiendecker-Foster, C; Lynch, AI3
Baimbridge, C; Bareis, CJ; Barzilay, J; Basile, JN; Black, HR; Dart, R; Davis, BR; Einhorn, PT; Gupta, AK; Hamilton, BP; Harris-Haywood, S; Haywood, LJ; Jafri, SZ; Louis, GT; Pressel, S; Scott, CL; Simmons, DL; Stanford, C; Whelton, PK; Wright, JT1
Cutler, JA; Davis, BR; Furberg, CD; Goldman, L; Heidenreich, PA; Lairson, DR; Nwachuku, C; Pressel, SL; Shlipak, MG1
Basile, JN; Bastien, A; Courtney, DL; Cushman, WC; Davis, BR; Einhorn, PT; Ford, CE; Hamilton, BP; Kirchner, K; Louis, GT; Preston, RA; Retta, TM; Vidt, DG; Weiss, RJ; Whelton, PK; Wright, JT1
Basile, JN; Carter, BL; Ernst, ME1
Parra, D; Rosenstein, R1
Arnett, DK; Barzilay, JI; Boerwinkle, E; Davis, BR; Eckfeldt, JH; Ford, CE; Irvin, MR; Kabagambe, EK; Lynch, AI; Tiwari, HK1
Alderman, MH; Calhoun, DA; Cushman, WC; Davis, BR; Eckfeldt, JH; Einhorn, PT; Ford, CE; Franklin, SS; Furberg, CD; Ong, ST; Oparil, S; Papademetriou, V; Piller, LB; Probstfield, JL1
Arnett, DK; Boerwinkle, E; Davis, BR; Eckfeldt, JH; Ford, CE; Leiendecker-Foster, C; Lynch, AI; Zhang, X1
Baimbridge, C; Barzilay, JI; Brown, CD; Colon, PJ; Cutler, JA; Davis, BR; Fine, LJ; Ford, CE; Grimm, RH; Gupta, AK; Haywood, LJ; Henriquez, MA; Ilamaythi, E; Oparil, S; Piller, LB; Preston, R; Rahman, M; Whelton, PK; Wright, JT1
Sowers, JR; Whaley-Connell, A1
Alderman, MH; Blumenthal, SS; Castaldo, RS; Cushman, WC; Cutler, JA; Davis, BR; Ford, CE; Franklin, SS; Furberg, CD; Gordon, D; Graumlich, JF; Pavlik, V; Preston, RA; Proschan, M1
Bath, LE; Denvir, MA; Gebbie, A; Mirsadraee, S; Sule, AA; Turtle, EJ; Webb, DJ1
Cushman, WC; Davis, BR; Ford, CE; Furberg, CD; Habib, GB; Haywood, LJ; Margolis, K; Oparil, S; Probstfield, JL; Whelton, PK; Wright, JT1
Alderman, MH; Davis, BR; Einhorn, PT; Ford, CE; Furberg, CD; Grimm, RH; Jafri, SZ; Oparil, S; Phillips, W; Piller, LB; Probstfield, JL; Whittle, J; Williamson, JD1
Cichelero, FT; Fuchs, FD; Fuchs, SC; Gus, M; Martinez, D; Moreira, LB1
Jeffers, BW; Wang, JG; Yan, P1
Davis, BR; Kostis, JB; Levitan, EB; Lynch, AI; Muntner, P; Oparil, S; Simpson, LM; Whelton, PK; Whittle, J1
Barzilay, JI; Dart, RA; Davis, BR; Einhorn, PT; Graves, JW; Pressel, SL; Reisin, E; Retta, TM; Saklayen, MG; Yamal, JM1
Baraniuk, S; Basile, JN; Dart, RA; Davis, BR; Ellsworth, AJ; Fendley, H; Habib, GB; Piller, LB; Probstfield, JL; Rahman, M; Simpson, LM; Whelton, PK1
Arnett, DK; Boerwinkle, E; Davis, BR; Eckfeldt, JH; Ford, CE; Irvin, MR; Sørensen, IF; Sørensen, P; Vazquez, AI1
Alderman, MH; Calhoun, DA; Cushman, WC; Davis, BR; Fendley, HF; Franklin, SS; Habib, GB; Oparil, S; Pressel, SL; Probstfield, JL; Sastrasinh, S; Yamal, JM1
Davis, BR; Lynch, AI; Muntner, P; Oparil, S; Rahman, M; Simpson, LM; Tanner, RM; Whelton, PK; Whittle, J1
Albert, CM; Alonso, A; Davis, BR; Dewland, TA; Haywood, LJ; Magnani, JW; Marcus, GM; Piller, LB; Soliman, EZ; Yamal, JM1
Beard, BL; Davis, BR; Ford, CE; Hamilton, BP; Marginean, H; Probstfield, JL; Suhan, PS; Whittle, J; Williamson, JD; Yamal, JM1
Barzilay, JI; Cushman, WC; Davis, BR; Einhorn, PT; Ghosh, A; Louis, GT; Margolis, KL; Oparil, S; Pressel, SL; Puttnam, R; Whelton, PK; Williamson, J1
Cushman, WC; Davis, BR; Einhorn, PT; Ernst, ME; Ghosh, A; Grimm, RH; Okin, PM; Oparil, S; Prineas, RJ; Soliman, EZ1
Bangalore, S; Black, HR; Calhoun, DA; Cushman, WC; Davis, BR; Kostis, JB; Muntner, PM; Pressel, SL; Probstfield, JL; Rahman, M; Whelton, PK1
Hesselink, DA; Hoorn, EJ; Moes, AD; van den Meiracker, AH; Zietse, R1
Bang, CN; Davis, BR; Devereux, RB; Okin, PM; Simpson, LM; Soliman, EZ1
Coifman, RR; Coppi, AC; Davis, BR; Dhruva, SS; Furberg, CD; Huang, C; Krumholz, HM; Li, SX; Lin, H; Pressel, SL; Spatz, ES; Warner, F; Xu, X1
Chae, JK; Chae, SC; Chang, KY; Cho, JR; Choi, JH; Choi, YJ; Chun, KJ; Han, KR; Han, SH; Heo, JH; Hong, BK; Hong, SJ; Jeong, HS; Jeong, MH; Jung, J; Kang, HJ; Kang, SM; Kim, CH; Kim, DW; Kim, JJ; Kim, KS; Kim, SH; Kim, WS; Kim, YD; Kwan, J; Lee, BK; Lee, SK; Lee, SU; Park, CG; Park, SH; Shin, DG; Shin, JH; Won, KH1
Albert, CM; Alonso, A; Davis, BR; Dewland, TA; Haywood, LJ; Marcus, GM; Simpson, LM; Soliman, EZ; Yamal, JM1
Armario, P; Banegas, JR; de la Cruz, JJ; de la Sierra, A; Gorostidi, M; Oliveras, A; Ruilope, LM; Segura, J; Vinyoles, E1
Cho, HJ; Choi, DJ; Han, KR; Jo, SH; Kim, EJ; Kim, SJ; Park, JJ; Park, SJ; Shin, J; Shin, JH; Song, JM1
Cheriyan, J; Chowienczyk, PJ; Cockcroft, JR; Collier, D; Coulson, JM; Dasgupta, I; Faconti, L; Glover, M; Heagerty, AM; Khong, TK; Lip, GYH; Mander, AP; Marchong, MN; Martin, U; McDonnell, BJ; McEniery, CM; Mukhtar, O; Padmanabhan, S; Saxena, M; Sever, PJ; Shiel, JI; Wilkinson, IB; Wych, J1
Amarasekara, S; Amarasena, N; Billot, L; de Silva, AP; de Silva, HA; Fernando, M; Guggilla, R; Jan, S; Jayawardena, J; Maulik, PK; Mendis, S; Munasinghe, J; Naik, N; Patel, A; Prabhakaran, D; Rajapakse, S; Ranasinghe, G; Rodgers, A; Salam, A; Selak, V; Senaratne, V; Stepien, S; Thom, S; Tisserra, N; Webster, R; Wijekoon, S; Wijeyasingam, S1
Davis, BR; Einhorn, PT; Ford, CE; Ghosh, A; Haywood, LJ; Piller, LB; Probstfield, JL; Simpson, LM; Soliman, EZ; Wright, JT1
Arnett, DK; Barzilay, JI; Davis, BR; Lai, D; Pressel, S; Previn, HE1
Davis, BR; Johnson, K; Oparil, S; Tereshchenko, LG1
Beach, JL; Davis, BR; Ishak, A; Juraschek, SP; Mukamal, KJ; Simpson, LM1
Anireddy, J; Dongala, T; Palakurthi, AK; Yalavarthi, RK1
Beach, JL; Davis, BR; Ishak, A; Juraschek, SP; Mukamal, KJ; Shmerling, RH; Simpson, LM1
Billot, L; de Silva, A; Guggilla, R; Jan, S; Maulik, PK; Mysore, J; Naik, N; Patel, A; Prabhakaran, D; Rodgers, A; Salam, A; Selak, V; Stepien, S; Thom, S; Wang, N; Webster, R1
Hong, SJ; Kim, HY; Kim, SY; Kim, W; Lim, SW; Park, S; Rhee, MY; Shin, J; Sung, KC1
Cosgrove, NM; Dobrzynski, JM; Kostis, JB; Kostis, WJ; Moreyra, AE; Vakil, D; Zinonos, S1
Choi, Y; Chung, JY; Jeon, I; Jung, J; Moon, SJ; Park, SI; Yu, KS1
Chang, TI; Itoga, NK; Montez-Rath, ME; Tawfik, DS1
Bettencourt, JL; Davis, BR; Du, XL; Simpson, LM; Tandy, BC1
Agrawal, S; Anand, J; Bachani, D; Doshi, M; Gaikwad, VB; Halder, SK; Kinholkar, B; Kumar, DA; Kumbhar, A; Mathur, R; Mehta, S; Sarkar, G; Sharma, A1
de Silva, HA; Di Tanna, GL; Gnanenthiran, SR; Guggilla, R; Jan, S; Maulik, PK; Naik, N; Patel, A; Prabhakaran, D; Rodgers, A; Salam, A; Schutte, AE; Selak, V; Thom, S; Wang, N; Webster, R1
Patel, A; Prajapati, P; Shah, S1
Gongal, P; Hanna, JM; Nanna, MG; Onuma, OK; Wang, SY1
Ahn, JC; Cho, EJ; Han, SH; Kang, SM; Kim, KH; Kim, KI; Kim, SY; Kim, W; Kim, YJ; Park, CG; Park, SJ; Park, SM; Shin, J; Shin, JH; Sohn, IS; Sung, JH; Sung, KC1
Gnanenthiran, SR; Guggilla, RK; Maulik, PK; Patel, A; Rodgers, A; Salam, A; Schutte, AE; Selak, V; Silva, A; Webster, R1
Cazabon, D; Hering, D; Krishna, A; Moran, AE; Pathni, AK; Sahoo, SK; Sharma, B1
Cho, DK; Cho, GY; Cho, JM; Heo, JH; Hong, SJ; Jeong, MH; Jung, JA; Kim, DH; Kim, SH; Kim, SY; Kim, W; Kwon, K; Lee, HY; Lee, JB; Lim, SW; Park, K; Park, S; Pyun, WB; Rha, SW; Rhee, MY; Shin, J; Sung, KC1
Borges, RB; Cichelero, FT; Fuchs, FD; Fuchs, SC; Hirakata, VN; Jorge, JA; Lucca, MB; Martinez, D1
Ahn, Y; Cha, KS; Chang, K; Cho, EJ; Choi, DJ; Choi, SY; Doh, JH; Hong, SJ; Hong, SP; Hwang, JY; Hyon, MS; Ihm, SH; Kang, WC; Kim, HS; Kim, MH; Kim, SH; Kim, WS; Kim, YH; Kwon, K; Lee, JH; Lee, N; Lim, SW; Rhee, MY; Shin, J; Son, JW; Yoo, BS1

Reviews

5 review(s) available for chlorthalidone and amlodipine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Recommendations for the management of special populations: racial and ethnic populations.
    American journal of hypertension, 2003, Volume: 16, Issue:11 Pt 2

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Black or African American; Calcium Channel Blockers; Chlorthalidone; Diuretics; Drug Therapy, Combination; Female; Humans; Hypertension; Lisinopril; Male; Ramipril; Randomized Controlled Trials as Topic

2003
[Recent intervention studies with antihypertensive drugs and their influence on guidelines].
    Medizinische Klinik (Munich, Germany : 1983), 2003, Dec-15, Volume: 98, Issue:12

    Topics: Adrenergic beta-Antagonists; Aged; Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzothiadiazines; Calcium Channel Blockers; Cardiovascular Diseases; Chlorthalidone; Clinical Trials as Topic; Death, Sudden, Cardiac; Diuretics; Drug Therapy, Combination; Humans; Hypertension; Lisinopril; Meta-Analysis as Topic; Middle Aged; Myocardial Infarction; Practice Guidelines as Topic; Prognosis; Randomized Controlled Trials as Topic; Risk; Risk Factors; Sodium Chloride Symporter Inhibitors; Stroke; Time Factors

2003
[ALLHAT trial--antithesis to the overuse of vasodilating antihypertensive drugs].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 3

    Topics: Adrenergic alpha-Antagonists; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzothiadiazines; Calcium Channel Blockers; Chlorthalidone; Coronary Disease; Diuretics; Double-Blind Method; Doxazosin; Humans; Hypertension; Lisinopril; Male; Randomized Controlled Trials as Topic; Sodium Chloride Symporter Inhibitors; Stroke

2004
Effects of amlodipine and other classes of antihypertensive drugs on long-term blood pressure variability: evidence from randomized controlled trials.
    Journal of the American Society of Hypertension : JASH, 2014, Volume: 8, Issue:5

    Topics: Amlodipine; Antihypertensive Agents; Atenolol; Blood Pressure; Cardiovascular Diseases; Chlorthalidone; Enalapril; Humans; Hypertension; Lisinopril; Losartan; Randomized Controlled Trials as Topic

2014

Trials

64 trial(s) available for chlorthalidone and amlodipine

ArticleYear
Treatment of Mild Hypertension Study. Final results. Treatment of Mild Hypertension Study Research Group.
    JAMA, 1993, Aug-11, Volume: 270, Issue:6

    Topics: Acebutolol; Aged; Amlodipine; Antihypertensive Agents; Chlorthalidone; Diastole; Double-Blind Method; Doxazosin; Echocardiography; Electrocardiography; Enalapril; Exercise; Female; Follow-Up Studies; Health Behavior; Humans; Hypertension; Long-Term Care; Male; Middle Aged; Treatment Outcome

1993
Efficacy and tolerance of antihypertensive treatment in men and women with stage 1 diastolic hypertension. Results of the Treatment of Mild Hypertension Study.
    Archives of internal medicine, 1996, Feb-26, Volume: 156, Issue:4

    Topics: Acebutolol; Aged; Amlodipine; Antihypertensive Agents; Chlorthalidone; Doxazosin; Enalapril; Female; Humans; Hygiene; Hypertension; Life Style; Male; Middle Aged; Nutritional Physiological Phenomena; Patient Education as Topic; Severity of Illness Index; Treatment Outcome

1996
Long-term effects on sexual function of five antihypertensive drugs and nutritional hygienic treatment in hypertensive men and women. Treatment of Mild Hypertension Study (TOMHS)
    Hypertension (Dallas, Tex. : 1979), 1997, Volume: 29, Issue:1 Pt 1

    Topics: Acebutolol; Aged; Amlodipine; Antihypertensive Agents; Chlorthalidone; Double-Blind Method; Doxazosin; Enalapril; Female; Humans; Hypertension; Libido; Male; Middle Aged; Orgasm; Penile Erection; Sexual Dysfunction, Physiological

1997
Major cardiovascular events in hypertensive patients randomized to doxazosin vs chlorthalidone: the antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT). ALLHAT Collaborative Research Group.
    JAMA, 2000, Apr-19, Volume: 283, Issue:15

    Topics: Adrenergic alpha-Antagonists; Aged; Amlodipine; Anticholesteremic Agents; Antihypertensive Agents; Cardiovascular Diseases; Chlorthalidone; Diuretics; Double-Blind Method; Doxazosin; Female; Humans; Hypertension; Lisinopril; Male; Middle Aged; Myocardial Infarction; Proportional Hazards Models; Risk; Survival Analysis

2000
Amlodipine versus chlorthalidone versus placebo in the treatment of stage I isolated systolic hypertension.
    American journal of hypertension, 2002, Volume: 15, Issue:1 Pt 1

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Placebos; Treatment Outcome

2002
Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).
    JAMA, 2002, Dec-18, Volume: 288, Issue:23

    Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Chlorthalidone; Diuretics; Double-Blind Method; Female; Humans; Hypertension; Lisinopril; Male; Middle Aged; Proportional Hazards Models; Risk Factors; Treatment Outcome

2002
The ALLHAT Trial. Diuretics are still the preferred initial drugs for high blood pressure.
    Cleveland Clinic journal of medicine, 2003, Volume: 70, Issue:3

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure Determination; Chlorthalidone; Diuretics; Dose-Response Relationship, Drug; Doxazosin; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Hypertension; Lisinopril; Male; Middle Aged; Patient Compliance; Probability; Risk Assessment; Severity of Illness Index; Treatment Outcome

2003
Are thiazide diuretics preferred as first-line therapy for hypertension? An appraisal of The Antihypertensive and Lipid-lowering Treatment to Prevent Heart Attack Trial (ALLHAT).
    Internal medicine journal, 2003, Volume: 33, Issue:7

    Topics: Aged; Amlodipine; Benzothiadiazines; Blood Chemical Analysis; Chlorthalidone; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Hypertension; Hypertrophy, Left Ventricular; Hypolipidemic Agents; Lisinopril; Male; Middle Aged; Myocardial Infarction; Queensland; Reference Values; Risk Assessment; Severity of Illness Index; Sodium Chloride Symporter Inhibitors; Stroke; Survival Analysis; Treatment Outcome

2003
Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitors or calcium channel blocker vs diuretic. The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).
    Current hypertension reports, 2003, Volume: 5, Issue:4

    Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Chlorthalidone; Coronary Disease; Diuretics; Double-Blind Method; Female; Humans; Hypertension; Lisinopril; Male

2003
Comparison of antihypertensive effects of an angiotensin-converting enzyme inhibitor, a calcium antagonist and a diuretic in patients with hypertension not controlled by angiotensin receptor blocker monotherapy.
    Journal of hypertension, 2005, Volume: 23, Issue:4

    Topics: Adolescent; Adult; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Chlorthalidone; Cross-Over Studies; Diuretics; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan

2005
Renal outcomes in high-risk hypertensive patients treated with an angiotensin-converting enzyme inhibitor or a calcium channel blocker vs a diuretic: a report from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).
    Archives of internal medicine, 2005, Apr-25, Volume: 165, Issue:8

    Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Chlorthalidone; Coronary Disease; Diuretics; Double-Blind Method; Female; Follow-Up Studies; Glomerular Filtration Rate; Humans; Hypertension; Incidence; Kidney Failure, Chronic; Lisinopril; Male; Middle Aged; Patient Compliance; Risk Factors; Treatment Outcome

2005
Pharmacogenetic association of the angiotensin-converting enzyme insertion/deletion polymorphism on blood pressure and cardiovascular risk in relation to antihypertensive treatment: the Genetics of Hypertension-Associated Treatment (GenHAT) study.
    Circulation, 2005, Jun-28, Volume: 111, Issue:25

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Chlorthalidone; Double-Blind Method; Doxazosin; Female; Follow-Up Studies; Genotype; Humans; Lisinopril; Male; Middle Aged; Peptidyl-Dipeptidase A; Pharmacogenetics; Polymorphism, Genetic; Predictive Value of Tests; Proportional Hazards Models; Risk Factors; Treatment Outcome

2005
Clinical outcomes in antihypertensive treatment of type 2 diabetes, impaired fasting glucose concentration, and normoglycemia: Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).
    Archives of internal medicine, 2005, Jun-27, Volume: 165, Issue:12

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Glucose; Chlorthalidone; Coronary Disease; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypoglycemia; Lisinopril; Male; Middle Aged; Treatment Outcome

2005
Cardiovascular outcomes in high-risk hypertensive patients stratified by baseline glomerular filtration rate.
    Annals of internal medicine, 2006, Feb-07, Volume: 144, Issue:3

    Topics: Aged; Amlodipine; Antihypertensive Agents; Cardiovascular Diseases; Chlorthalidone; Chronic Disease; Double-Blind Method; Female; Glomerular Filtration Rate; Humans; Hypertension; Kidney Diseases; Kidney Failure, Chronic; Lisinopril; Male; Middle Aged; Risk Factors

2006
Role of diuretics in the prevention of heart failure: the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial.
    Circulation, 2006, May-09, Volume: 113, Issue:18

    Topics: Adrenergic beta-Antagonists; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Calcium Channel Blockers; Chlorthalidone; Diuretics; Double-Blind Method; Doxazosin; Drug Therapy, Combination; Female; Heart Failure; Hospitalization; Humans; Hypertension; Incidence; Lisinopril; Male; Middle Aged; Myocardial Infarction; Proportional Hazards Models; Risk; Treatment Outcome

2006
Antihypertensive therapy, the alpha-adducin polymorphism, and cardiovascular disease in high-risk hypertensive persons: the Genetics of Hypertension-Associated Treatment Study.
    The pharmacogenomics journal, 2007, Volume: 7, Issue:2

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calmodulin-Binding Proteins; Chlorthalidone; Coronary Disease; Double-Blind Method; Doxazosin; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glycine; Humans; Hypertension; Incidence; Kaplan-Meier Estimate; Lisinopril; Male; Middle Aged; Patient Selection; Polymorphism, Genetic; Proportional Hazards Models; Risk Assessment; Risk Factors; Sex Factors; Time Factors; Treatment Outcome; Tryptophan

2007
Incidence and predictors of angioedema in elderly hypertensive patients at high risk for cardiovascular disease: a report from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).
    Journal of clinical hypertension (Greenwich, Conn.), 2006, Volume: 8, Issue:9

    Topics: Aged; Aged, 80 and over; Amlodipine; Angioedema; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Canada; Cardiovascular Diseases; Chlorthalidone; Female; Humans; Hypertension; Incidence; Lisinopril; Male; Middle Aged; Prognosis; Risk Factors; Time Factors; United States

2006
Fasting glucose levels and incident diabetes mellitus in older nondiabetic adults randomized to receive 3 different classes of antihypertensive treatment: a report from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHA
    Archives of internal medicine, 2006, Nov-13, Volume: 166, Issue:20

    Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Glucose; Calcium Channel Blockers; Chi-Square Distribution; Chlorthalidone; Diabetes Mellitus; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypertension; Incidence; Lisinopril; Male; Middle Aged; Myocardial Infarction; Proportional Hazards Models; Sodium Chloride Symporter Inhibitors; Treatment Outcome

2006
Antihypertensive efficacy and safety of manidipine versus amlodipine in elderly subjects with isolated systolic hypertension: MAISH study.
    Clinical drug investigation, 2007, Volume: 27, Issue:9

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Chlorthalidone; Dihydropyridines; Diuretics; Double-Blind Method; Drug Therapy, Combination; Europe; Female; Humans; Hypertension; Male; Middle Aged; Nitrobenzenes; Piperazines; Risk Assessment; Risk Factors; Systole; Time Factors; Treatment Outcome

2007
Blood pressure control in Hispanics in the antihypertensive and lipid-lowering treatment to prevent heart attack trial.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 50, Issue:5

    Topics: Aged; Amlodipine; Antihypertensive Agents; Atenolol; Black People; Blood Pressure; Canada; Chlorthalidone; Clonidine; Double-Blind Method; Doxazosin; Female; Heart Diseases; Hispanic or Latino; Humans; Hydralazine; Hypertension; Hypolipidemic Agents; Lisinopril; Male; Middle Aged; Puerto Rico; Reserpine; Treatment Outcome; United States; United States Virgin Islands; White People

2007
Clinical outcomes by race in hypertensive patients with and without the metabolic syndrome: Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).
    Archives of internal medicine, 2008, Jan-28, Volume: 168, Issue:2

    Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Black People; Chlorthalidone; Double-Blind Method; Doxazosin; Female; Humans; Hypertension; Lisinopril; Male; Metabolic Syndrome; Middle Aged; Treatment Outcome; White People

2008
Cost-effectiveness of chlorthalidone, amlodipine, and lisinopril as first-step treatment for patients with hypertension: an analysis of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).
    Journal of general internal medicine, 2008, Volume: 23, Issue:5

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Chlorthalidone; Cost-Benefit Analysis; Diuretics; Female; Humans; Hypertension; Kaplan-Meier Estimate; Lisinopril; Male; Middle Aged; Myocardial Infarction; Quality-Adjusted Life Years

2008
Blood pressure control by drug group in the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).
    Journal of clinical hypertension (Greenwich, Conn.), 2008, Volume: 10, Issue:10

    Topics: Aged; Aged, 80 and over; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Chlorthalidone; Diuretics; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypertension; Lisinopril; Logistic Models; Male; Middle Aged; Treatment Outcome

2008
Antihypertensive pharmacogenetic effect of fibrinogen-beta variant -455G>A on cardiovascular disease, end-stage renal disease, and mortality: the GenHAT study.
    Pharmacogenetics and genomics, 2009, Volume: 19, Issue:6

    Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Chlorthalidone; Coronary Disease; Diuretics; Fibrinogen; Genetic Variation; Genotype; Humans; Hypertension; Kidney Failure, Chronic; Lisinopril; Middle Aged; Stroke; Treatment Outcome

2009
Pharmacogenetic association of hypertension candidate genes with fasting glucose in the GenHAT Study.
    Journal of hypertension, 2010, Volume: 28, Issue:10

    Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Glucose; Calcium Channel Blockers; Chlorthalidone; Diabetes Mellitus; Diuretics; Double-Blind Method; Epithelial Sodium Channels; Fasting; Female; Humans; Hypertension; Lisinopril; Longitudinal Studies; Male; Middle Aged; Pharmacogenetics; Polymorphism, Single Nucleotide; Retrospective Studies; Risk Factors; Treatment Outcome

2010
Gene panels to help identify subgroups at high and low risk of coronary heart disease among those randomized to antihypertensive treatment: the GenHAT study.
    Pharmacogenetics and genomics, 2012, Volume: 22, Issue:5

    Topics: Aged; Amlodipine; Antihypertensive Agents; Chlorthalidone; Coronary Disease; Doxazosin; Female; Follow-Up Studies; Genetic Association Studies; Genotype; Humans; Hypertension; Lisinopril; Male; Middle Aged; Myocardial Infarction; Polymorphism, Genetic; Proportional Hazards Models; Risk Factors; Treatment Outcome

2012
Clinical significance of incident hypokalemia and hyperkalemia in treated hypertensive patients in the antihypertensive and lipid-lowering treatment to prevent heart attack trial.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 59, Issue:5

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Chemical Analysis; Cardiovascular Diseases; Chlorthalidone; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Hyperkalemia; Hypertension; Hypokalemia; Incidence; Kaplan-Meier Estimate; Lisinopril; Male; Middle Aged; Myocardial Infarction; Proportional Hazards Models; Prospective Studies; Risk Assessment; Survival Rate; Treatment Outcome

2012
Pharmacogenetic association of NOS3 variants with cardiovascular disease in patients with hypertension: the GenHAT study.
    PloS one, 2012, Volume: 7, Issue:3

    Topics: Aged; Alleles; Amlodipine; Antihypertensive Agents; Cardiovascular Diseases; Chlorthalidone; Double-Blind Method; Female; Follow-Up Studies; Genotype; Heart Failure; Humans; Hypertension; Lisinopril; Male; Middle Aged; Nitric Oxide Synthase Type III; Polymorphism, Single Nucleotide; Risk Factors; Stroke

2012
Long-term renal and cardiovascular outcomes in Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) participants by baseline estimated GFR.
    Clinical journal of the American Society of Nephrology : CJASN, 2012, Volume: 7, Issue:6

    Topics: Amlodipine; Antihypertensive Agents; Canada; Chlorthalidone; Chronic Disease; Coronary Disease; Double-Blind Method; Female; Glomerular Filtration Rate; Heart Failure; Humans; Hypertension; Hypolipidemic Agents; Incidence; Kaplan-Meier Estimate; Kidney; Kidney Diseases; Kidney Failure, Chronic; Lisinopril; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Proportional Hazards Models; Puerto Rico; Risk Assessment; Risk Factors; Severity of Illness Index; Stroke; Time Factors; Treatment Outcome; United States; United States Virgin Islands

2012
Mortality and morbidity during and after Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial: results by sex.
    Hypertension (Dallas, Tex. : 1979), 2013, Volume: 61, Issue:5

    Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Chlorthalidone; Coronary Disease; Diuretics; Female; Follow-Up Studies; Heart Failure; Humans; Hypertension; Hypolipidemic Agents; Incidence; Lisinopril; Longitudinal Studies; Male; Middle Aged; Myocardial Infarction; Risk Factors; Sex Factors; Stroke

2013
Risk of hospitalized gastrointestinal bleeding in persons randomized to diuretic, ACE-inhibitor, or calcium-channel blocker in ALLHAT.
    Journal of clinical hypertension (Greenwich, Conn.), 2013, Volume: 15, Issue:11

    Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Chlorthalidone; Diuretics; Female; Gastrointestinal Hemorrhage; Hospitalization; Humans; Hypertension; Incidence; Lisinopril; Male; Middle Aged; Myocardial Infarction; Risk Factors; Treatment Outcome

2013
The effect of antihypertensive agents on sleep apnea: protocol for a randomized controlled trial.
    Trials, 2014, Jan-02, Volume: 15

    Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Chlorthalidone; Clinical Protocols; Diuretics; Double-Blind Method; Drug Therapy, Combination; Humans; Hypertension; Polysomnography; Research Design; Sleep; Sleep Apnea Syndromes; Time Factors; Treatment Outcome

2014
Effect of chlorthalidone, amlodipine, and lisinopril on visit-to-visit variability of blood pressure: results from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial.
    Journal of clinical hypertension (Greenwich, Conn.), 2014, Volume: 16, Issue:5

    Topics: Acute Coronary Syndrome; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Calcium Channel Blockers; Chlorthalidone; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hypertension; Hypolipidemic Agents; Lisinopril; Male; Office Visits; Prognosis; Risk Factors; Treatment Outcome

2014
Blood pressure control and cardiovascular outcomes in normal-weight, overweight, and obese hypertensive patients treated with three different antihypertensives in ALLHAT.
    Journal of hypertension, 2014, Volume: 32, Issue:7

    Topics: Aged; Aged, 80 and over; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Body Mass Index; Calcium Channel Blockers; Cardiovascular Diseases; Chlorthalidone; Cohort Studies; Diuretics; Double-Blind Method; Female; Humans; Hypertension; Lisinopril; Male; Middle Aged; Obesity; Overweight; Prospective Studies

2014
Characteristics and long-term follow-up of participants with peripheral arterial disease during ALLHAT.
    Journal of general internal medicine, 2014, Volume: 29, Issue:11

    Topics: Aged; Amlodipine; Antihypertensive Agents; Chlorthalidone; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypertension; Kaplan-Meier Estimate; Lisinopril; Male; Middle Aged; Peripheral Arterial Disease; United States

2014
Stroke outcomes among participants randomized to chlorthalidone, amlodipine or lisinopril in ALLHAT.
    Journal of the American Society of Hypertension : JASH, 2014, Volume: 8, Issue:11

    Topics: Age Factors; Aged; Amlodipine; Cause of Death; Chlorthalidone; Confidence Intervals; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hypertension; Kaplan-Meier Estimate; Lisinopril; Male; Middle Aged; Proportional Hazards Models; Risk Assessment; Severity of Illness Index; Sex Factors; Stroke; Survival Rate; Treatment Outcome

2014
Effect of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) on Conduction System Disease.
    JAMA internal medicine, 2016, 08-01, Volume: 176, Issue:8

    Topics: Aged; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Chlorthalidone; Electrocardiography; Female; Heart Conduction System; Humans; Lisinopril; Male; Middle Aged; Prognosis

2016
Clinical and demographic correlates of medication and visit adherence in a large randomized controlled trial.
    BMC health services research, 2016, 07-08, Volume: 16

    Topics: Aged; Amlodipine; Antihypertensive Agents; Appointments and Schedules; Black People; Chlorthalidone; Demography; Double-Blind Method; Female; Humans; Hypertension; Lisinopril; Male; Medication Adherence; Middle Aged; Myocardial Infarction; North America; Patient Compliance; Retrospective Studies; Treatment Outcome

2016
Association of 3 Different Antihypertensive Medications With Hip and Pelvic Fracture Risk in Older Adults: Secondary Analysis of a Randomized Clinical Trial.
    JAMA internal medicine, 2017, Jan-01, Volume: 177, Issue:1

    Topics: Aged; Amlodipine; Antihypertensive Agents; Chlorthalidone; Female; Follow-Up Studies; Hip Fractures; Humans; Intention to Treat Analysis; Lisinopril; Male; Pelvic Bones; Risk Assessment; Risk Factors; United States

2017
Electrocardiographic measures of left ventricular hypertrophy in the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial.
    Journal of the American Society of Hypertension : JASH, 2016, Volume: 10, Issue:12

    Topics: Aged; Amlodipine; Antihypertensive Agents; Chlorthalidone; Electrocardiography; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Hypolipidemic Agents; Incidence; Lipids; Lisinopril; Male; Middle Aged; Myocardial Infarction; Prevalence; Risk Factors

2016
Treatment-Resistant Hypertension and Outcomes Based on Randomized Treatment Group in ALLHAT.
    The American journal of medicine, 2017, Volume: 130, Issue:4

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Chlorthalidone; Diuretics; Drug Therapy, Combination; Female; Humans; Hypertension; Lisinopril; Male; Treatment Failure; Treatment Outcome

2017
Chlorthalidone Versus Amlodipine for Hypertension in Kidney Transplant Recipients Treated With Tacrolimus: A Randomized Crossover Trial.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2017, Volume: 69, Issue:6

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Chlorthalidone; Cross-Over Studies; Edema; Female; Glomerular Filtration Rate; Graft Rejection; Humans; Hypertension; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Transplantation; Male; Middle Aged; Proteinuria; Tacrolimus; Treatment Outcome

2017
Electrocardiographic Left Ventricular Hypertrophy Predicts Cardiovascular Morbidity and Mortality in Hypertensive Patients: The ALLHAT Study.
    American journal of hypertension, 2017, Sep-01, Volume: 30, Issue:9

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Cause of Death; Chlorthalidone; Disease Progression; Electrocardiography; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Lisinopril; Male; Middle Aged; Predictive Value of Tests; Risk Factors; Time Factors; Treatment Outcome; Ventricular Function, Left; Ventricular Remodeling

2017
Heterogeneity in Early Responses in ALLHAT (Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial).
    Hypertension (Dallas, Tex. : 1979), 2017, Volume: 70, Issue:1

    Topics: Aged; Amlodipine; Analysis of Variance; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Chlorthalidone; Doxazosin; Drug Monitoring; Female; Humans; Hyperlipidemias; Hypertension; Hypolipidemic Agents; Lisinopril; Male; Middle Aged; Treatment Outcome

2017
Comparison of Fixed-dose Combinations of Amlodipine/Losartan Potassium/Chlorthalidone and Amlodipine/Losartan Potassium in Patients With Stage 2 Hypertension Inadequately Controlled With Amlodipine/Losartan Potassium: A Randomized, Double-blind, Multicent
    Clinical therapeutics, 2017, Volume: 39, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Double-Blind Method; Drug Combinations; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Treatment Outcome; Young Adult

2017
Pharmacologic Prevention of Incident Atrial Fibrillation: Long-Term Results From the ALLHAT (Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial).
    Circulation. Arrhythmia and electrophysiology, 2017, Volume: 10, Issue:12

    Topics: Amlodipine; Antihypertensive Agents; Atrial Fibrillation; Atrial Flutter; Chlorthalidone; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Incidence; Lisinopril; Male; Middle Aged; Myocardial Infarction; Primary Prevention; Risk Factors; Time Factors; Treatment Outcome; United States

2017
S-amlodipine plus chlorthalidone vs. S-amlodipine plus telmisartan in hypertensive patients unresponsive to amlodipine monotherapy: study protocol for a randomized controlled trial.
    Trials, 2018, Jun-20, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Chlorthalidone; Clinical Trials, Phase IV as Topic; Diuretics; Double-Blind Method; Drug Combinations; Drug Resistance; Equivalence Trials as Topic; Female; Humans; Hypertension; Male; Middle Aged; Multicenter Studies as Topic; Prospective Studies; Republic of Korea; Telmisartan; Time Factors; Treatment Outcome; Young Adult

2018
A randomized controlled crossover trial evaluating differential responses to antihypertensive drugs (used as mono- or dual therapy) on the basis of ethnicity: The comparIsoN oF Optimal Hypertension RegiMens; part of the Ancestry Informative Markers in HYp
    American heart journal, 2018, Volume: 204

    Topics: Adolescent; Adult; Aged; Amlodipine; Antihypertensive Agents; Asian People; Black People; Chlorthalidone; Cross-Over Studies; Drug Administration Schedule; Drug Therapy, Combination; Hemodynamics; Humans; Hypertension; Lisinopril; Middle Aged; Prospective Studies; United Kingdom; White People; Young Adult

2018
Fixed Low-Dose Triple Combination Antihypertensive Medication vs Usual Care for Blood Pressure Control in Patients With Mild to Moderate Hypertension in Sri Lanka: A Randomized Clinical Trial.
    JAMA, 2018, 08-14, Volume: 320, Issue:6

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Chlorthalidone; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Hypertension; Male; Medication Adherence; Middle Aged; Potassium; Sri Lanka; Telmisartan

2018
Risk Factors Influencing Outcomes of Atrial Fibrillation in ALLHAT.
    Journal of the National Medical Association, 2018, Volume: 110, Issue:4

    Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Atrial Fibrillation; Atrial Flutter; Chlorthalidone; Coronary Disease; Double-Blind Method; Female; Heart Failure; Humans; Hypertension; Lisinopril; Male; Myocardial Infarction; Proportional Hazards Models; Risk Factors; Stroke

2018
The Interaction of a Diabetes Gene Risk Score With 3 Different Antihypertensive Medications for Incident Glucose-level Elevation.
    American journal of hypertension, 2019, 03-16, Volume: 32, Issue:4

    Topics: Alkadienes; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Calcium Channel Blockers; Chlorthalidone; Diabetes Mellitus; Female; Gene Frequency; Genetic Testing; Genotype; Humans; Hypertension; Lisinopril; Male; Middle Aged; Polymorphism, Single Nucleotide; Prognosis; Risk Factors; Sodium Chloride Symporter Inhibitors

2019
Prevention of Heart Failure in Hypertension-Disentangling the Role of Evolving Left Ventricular Hypertrophy and Blood Pressure Lowering: The ALLHAT Study.
    Journal of the American Heart Association, 2019, 04-16, Volume: 8, Issue:8

    Topics: Aged; Amlodipine; Antihypertensive Agents; Causality; Chlorthalidone; Doxazosin; Electrocardiography; Female; Heart Failure; Humans; Hypertension; Hypertrophy, Left Ventricular; Linear Models; Lisinopril; Logistic Models; Male; Middle Aged; Personal Protective Equipment; Proportional Hazards Models

2019
Association of Low-Dose Triple Combination Therapy With Therapeutic Inertia and Prescribing Patterns in Patients With Hypertension: A Secondary Analysis of the TRIUMPH Trial.
    JAMA cardiology, 2020, 11-01, Volume: 5, Issue:11

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Dose-Response Relationship, Drug; Drug Prescriptions; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Retrospective Studies; Telmisartan; Treatment Outcome

2020
Low-Dose Triple Antihypertensive Combination Therapy in Patients with Hypertension: A Randomized, Double-Blind, Phase II Study.
    Drug design, development and therapy, 2020, Volume: 14

    Topics: Aged; Amlodipine; Antihypertensive Agents; Chlorthalidone; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Losartan; Male; Middle Aged

2020
Monotherapy treatment with chlorthalidone or amlodipine in the systolic blood pressure intervention trial (SPRINT).
    Journal of clinical hypertension (Greenwich, Conn.), 2021, Volume: 23, Issue:7

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Humans; Hypertension; Treatment Outcome

2021
Pharmacokinetics of a Fixed-Dose Combination of Amlodipine/Losartan and Chlorthalidone Compared to Concurrent Administration of the Separate Components.
    Clinical pharmacology in drug development, 2022, Volume: 11, Issue:1

    Topics: Amlodipine; Chlorthalidone; Cross-Over Studies; Drug Combinations; Humans; Losartan

2022
Risk of hospitalized and non-hospitalized gastrointestinal bleeding in ALLHAT trial participants receiving diuretic, ACE-inhibitor, or calcium-channel blocker.
    PloS one, 2021, Volume: 16, Issue:11

    Topics: Aged; Aged, 80 and over; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium; Calcium Channel Blockers; Chlorthalidone; Diuretics; Double-Blind Method; Female; Gastrointestinal Hemorrhage; Hospitalization; Humans; Hypertension; Lisinopril; Male; Middle Aged; Myocardial Infarction; Risk Factors; United States

2021
Fixed-dose Combination of Metoprolol, Telmisartan, and Chlorthalidone for Essential Hypertension in Adults with Stable Coronary Artery Disease: Phase III Study.
    Advances in therapy, 2022, Volume: 39, Issue:2

    Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Coronary Artery Disease; Drug Therapy, Combination; Essential Hypertension; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Metoprolol; Telmisartan; Tetrazoles

2022
Association of Low-Dose Triple Combination Therapy vs Usual Care With Time at Target Blood Pressure: A Secondary Analysis of the TRIUMPH Randomized Clinical Trial.
    JAMA cardiology, 2022, 06-01, Volume: 7, Issue:6

    Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Female; Humans; Hypertension; Male; Middle Aged

2022
Efficacy and safety of low-dose antihypertensive combination of amlodipine, telmisartan, and chlorthalidone: A randomized, double-blind, parallel, phase II trial.
    Journal of clinical hypertension (Greenwich, Conn.), 2022, Volume: 24, Issue:10

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Essential Hypertension; Humans; Hypertension; Telmisartan; Treatment Outcome

2022
Reduced efficacy of blood pressure lowering drugs in the presence of diabetes mellitus-results from the TRIUMPH randomised controlled trial.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2023, Volume: 46, Issue:1

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Diabetes Mellitus; Drug Combinations; Humans; Hypertension

2023
Comparison of efficacy and safety between third-dose triple and third-dose dual antihypertensive combination therapies in patients with hypertension.
    Journal of clinical hypertension (Greenwich, Conn.), 2023, Volume: 25, Issue:5

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Double-Blind Method; Drug Therapy, Combination; Humans; Hypertension; Hypotension; Losartan; Treatment Outcome

2023
Effects of chlorthalidone plus amiloride compared with amlodipine on short-term blood pressure variability in individuals with hypertension and obstructive sleep apnea: a randomized controlled trial.
    Blood pressure monitoring, 2023, Dec-01, Volume: 28, Issue:6

    Topics: Adult; Amiloride; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Chlorthalidone; Female; Humans; Hypertension; Male; Middle Aged; Sleep Apnea, Obstructive

2023
Efficacy and safety of standard dose triple combination of telmisartan 80 mg/amlodipine 5 mg/chlorthalidone 25 mg in primary hypertension: A randomized, double-blind, active-controlled, multicenter phase 3 trial.
    Journal of clinical hypertension (Greenwich, Conn.), 2023, Volume: 25, Issue:9

    Topics: Aged; Amlodipine; Chlorthalidone; Essential Hypertension; Female; Humans; Hypertension; Leukemia, Myeloid, Acute; Male; Middle Aged; Telmisartan

2023

Other Studies

48 other study(ies) available for chlorthalidone and amlodipine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
[Are all antihypertensive agents equal? Cardiovascular events in hypertensive patients randomized to treatment with doxazosin or chlorthalidone. The ALLHAT study].
    Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology, 2000, Volume: 1, Issue:9

    Topics: Adrenergic alpha-Antagonists; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Canada; Chlorthalidone; Coronary Disease; Diuretics; Doxazosin; Humans; Hypertension; Lisinopril; Multicenter Studies as Topic; Myocardial Infarction; Randomized Controlled Trials as Topic; Risk; United States

2000
[Old or new antihypertensive drugs? Consequences from ALLHAT. Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial].
    Deutsche medizinische Wochenschrift (1946), 2003, Jan-31, Volume: 128, Issue:5

    Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Chlorthalidone; Clinical Trials as Topic; Diuretics; Doxazosin; Female; Humans; Hypertension; Lisinopril; Male; Middle Aged; Myocardial Infarction; Research Design; Treatment Outcome

2003
[ALLHAT--the most comprehensive antihypertensive treatment trial in the world. The significance of thiazide diuretics for patients older than 55 years is confirmed].
    Lakartidningen, 2003, Feb-06, Volume: 100, Issue:6

    Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzothiadiazines; Calcium Channel Blockers; Cardiovascular Diseases; Chlorthalidone; Diuretics; Female; Humans; Hypertension; Lisinopril; Male; Middle Aged; Randomized Controlled Trials as Topic; Risk Factors; Sodium Chloride Symporter Inhibitors

2003
[Consequences of ALLHAT: Thiazides rehabilitated--time to change prescription patterns].
    Lakartidningen, 2003, Feb-06, Volume: 100, Issue:6

    Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzothiadiazines; Calcium Channel Blockers; Chlorthalidone; Cost Savings; Diuretics; Female; Humans; Hypertension; Lisinopril; Male; Middle Aged; Practice Patterns, Physicians'; Randomized Controlled Trials as Topic; Sodium Chloride Symporter Inhibitors

2003
ALLHAT finds diuretics best for initial hypertension therapy.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2003, Feb-01, Volume: 60, Issue:3

    Topics: Amlodipine; Antihypertensive Agents; Chlorthalidone; Clinical Trials as Topic; Diuretics; Humans; Hypertension; Lisinopril; Myocardial Infarction

2003
Diuretics: first choice for treating high BP.
    Health news (Waltham, Mass.), 2003, Volume: 9, Issue:2

    Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Chlorthalidone; Diuretics; Drug Therapy, Combination; Humans; Hypertension; Lisinopril; Middle Aged

2003
[Established blood pressure drug wins out in a comparative study. In hypertension, a diuretic first!].
    MMW Fortschritte der Medizin, 2003, Jan-16, Volume: 145, Issue:1-2

    Topics: Adrenergic alpha-Antagonists; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzothiadiazines; Calcium Channel Blockers; Chlorthalidone; Coronary Disease; Diuretics; Double-Blind Method; Doxazosin; Humans; Hypertension; Lisinopril; Middle Aged; Randomized Controlled Trials as Topic; Sodium Chloride Symporter Inhibitors

2003
Hats off to an old blood pressure drug. For treating high blood pressure, an old--and inexpensive--medication is a great place to start or a good one to add.
    Harvard heart letter : from Harvard Medical School, 2003, Volume: 13, Issue:7

    Topics: Amlodipine; Antihypertensive Agents; Chlorthalidone; Clinical Trials as Topic; Diuretics; Humans; Hypertension; Lisinopril

2003
[What are the sequelae of the ALLHAT Study?].
    Deutsche medizinische Wochenschrift (1946), 2003, Mar-28, Volume: 128, Issue:13

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Critical Pathways; Humans; Hypertension; Lisinopril; Randomized Controlled Trials as Topic

2003
Diuretics: older, cheaper, better.
    The Johns Hopkins medical letter health after 50, 2003, Volume: 15, Issue:2

    Topics: Adrenergic beta-Antagonists; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Benzothiadiazines; Blood Pressure; Calcium Channel Blockers; Chlorthalidone; Clinical Trials as Topic; Diuretics; Doxazosin; Humans; Hypertension; Lisinopril; Middle Aged; Sodium Chloride Symporter Inhibitors

2003
[ALLHAT: Old Hat Hits All? On selection of the optimal antihypertensive drug].
    Wiener klinische Wochenschrift, 2003, Mar-31, Volume: 115, Issue:5-6

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Cause of Death; Chlorthalidone; Dose-Response Relationship, Drug; Double-Blind Method; Doxazosin; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hypertension; Lisinopril; Long-Term Care; Male; Middle Aged; Randomized Controlled Trials as Topic; Treatment Outcome

2003
Diuretics are better first-line antihypertensive therapy than calcium channel blockers and ACE inhibitors.
    Report on medical guidelines & outcomes research, 2003, Jan-24, Volume: 14, Issue:2

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Chlorthalidone; Diuretics; Humans; Hypertension; Lisinopril; Randomized Controlled Trials as Topic; Risk Factors; Treatment Outcome; United States

2003
A cheaper way to control high blood pressure.
    Harvard health letter, 2003, Volume: 28, Issue:5

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Chlorthalidone; Clinical Trials as Topic; Controlled Clinical Trials as Topic; Diuretics; Humans; Hypertension; Lisinopril

2003
ALLHAT--all hit or all miss? Key questions still remain.
    The American journal of cardiology, 2003, Aug-01, Volume: 92, Issue:3

    Topics: Amlodipine; Antihypertensive Agents; Black People; Chlorthalidone; Humans; Hypolipidemic Agents; Lisinopril; Myocardial Infarction; Research Design; Survival Analysis; White People

2003
[The new (old) knowledge in primary prevention of stroke. It depends on lowering of blood pressure].
    MMW Fortschritte der Medizin, 2003, Volume: 145 Suppl 1

    Topics: Adrenergic alpha-Antagonists; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Black or African American; Calcium Channel Blockers; Chlorthalidone; Clinical Trials as Topic; Doxazosin; Follow-Up Studies; Heart Failure; Humans; Lisinopril; Middle Aged; Myocardial Infarction; Primary Prevention; Stroke; Time Factors

2003
ALLHAT: what has it taught us so far?
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2004, Sep-28, Volume: 171, Issue:7

    Topics: Amlodipine; Antihypertensive Agents; Chlorthalidone; Humans; Hypertension; Lisinopril; Myocardial Infarction; Outcome Assessment, Health Care; Randomized Controlled Trials as Topic

2004
Outcomes in hypertensive black and nonblack patients treated with chlorthalidone, amlodipine, and lisinopril.
    JAMA, 2005, Apr-06, Volume: 293, Issue:13

    Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Black People; Calcium Channel Blockers; Cardiovascular Diseases; Chlorthalidone; Diuretics; Humans; Hypertension; Lisinopril; Middle Aged; Randomized Controlled Trials as Topic; Treatment Outcome

2005
Summaries for patients. Do the effects of blood pressure drugs differ by kidney function?
    Annals of internal medicine, 2006, Feb-07, Volume: 144, Issue:3

    Topics: Aged; Amlodipine; Antihypertensive Agents; Cardiovascular Diseases; Chlorthalidone; Chronic Disease; Double-Blind Method; Female; Glomerular Filtration Rate; Humans; Hypertension; Kidney Diseases; Kidney Failure, Chronic; Lisinopril; Male; Middle Aged; Risk Factors

2006
Omission of drug dose information.
    Archives of internal medicine, 2006, Feb-13, Volume: 166, Issue:3

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Chlorthalidone; Dose-Response Relationship, Drug; Humans; Hypertension; Lisinopril; Randomized Controlled Trials as Topic

2006
Survival of severe amlodipine intoxication due to medical intensive care.
    Forensic science international, 2006, Sep-12, Volume: 161, Issue:2-3

    Topics: Adult; Amlodipine; Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Blockers; Chlorthalidone; Critical Care; Diuretics; Drug Overdose; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Half-Life; Humans; Male; Mefenamic Acid; Suicide, Attempted

2006
Blood pressure drugs can boost blood sugar. Depending on the drug, though, it may not matter.
    Harvard heart letter : from Harvard Medical School, 2007, Volume: 17, Issue:6

    Topics: Amlodipine; Antihypertensive Agents; Blood Glucose; Chlorthalidone; Clinical Trials as Topic; Diabetes Mellitus; Diuretics; Humans; Lisinopril

2007
The putative link between glycemic control and cardiac arrhythmias.
    Archives of internal medicine, 2007, Jul-09, Volume: 167, Issue:13

    Topics: Amlodipine; Antihypertensive Agents; Arrhythmias, Cardiac; Blood Glucose; Chlorthalidone; Diabetes Mellitus; Diuretics; Humans; Hypertension; Lisinopril

2007
Metabolic and clinical outcomes in nondiabetic individuals with the metabolic syndrome assigned to chlorthalidone, amlodipine, or lisinopril as initial treatment for hypertension: a report from the Antihypertensive and Lipid-Lowering Treatment to Prevent
    Diabetes care, 2008, Volume: 31, Issue:2

    Topics: Aged; Amlodipine; Antihypertensive Agents; Atherosclerosis; Blood Pressure; Chlorthalidone; Cohort Studies; Coronary Disease; Female; Humans; Hypertension; Hypolipidemic Agents; Lisinopril; Male; Metabolic Syndrome; Middle Aged; Myocardial Infarction; Risk Factors

2008
Pharmacogenetic association of the NPPA T2238C genetic variant with cardiovascular disease outcomes in patients with hypertension.
    JAMA, 2008, Jan-23, Volume: 299, Issue:3

    Topics: Aged; Amlodipine; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Cardiovascular Diseases; Chlorthalidone; Diuretics; Doxazosin; Female; Genotype; Humans; Hypertension; Lisinopril; Male; Middle Aged; Pharmacogenetics; Polymorphism, Single Nucleotide

2008
All thiazide-like diuretics are not chlorthalidone: putting the ACCOMPLISH study into perspective.
    Journal of clinical hypertension (Greenwich, Conn.), 2009, Volume: 11, Issue:1

    Topics: Amlodipine; Antihypertensive Agents; Benzazepines; Chlorthalidone; Diuretics; Humans; Hydrochlorothiazide; Hypertension; Multicenter Studies as Topic; Randomized Controlled Trials as Topic

2009
Benazepril plus amlodipine or hydrochlorothiazide for hypertension.
    The New England journal of medicine, 2009, Mar-12, Volume: 360, Issue:11

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Calcium Channel Blockers; Chlorthalidone; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia

2009
Strengthening diuretics' role in hypertension.
    Managed care (Langhorne, Pa.), 2010, Volume: 19, Issue:9

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Chlorthalidone; Diuretics; Humans; Hypertension; Lisinopril

2010
Initial choice of antihypertensive on long-term cardiovascular outcomes in CKD.
    Clinical journal of the American Society of Nephrology : CJASN, 2012, Volume: 7, Issue:6

    Topics: Amlodipine; Antihypertensive Agents; Chlorthalidone; Female; Glomerular Filtration Rate; Humans; Hypertension; Hypolipidemic Agents; Kidney; Kidney Diseases; Lisinopril; Male; Myocardial Infarction

2012
How much effect of different antihypertensive medications on cardiovascular outcomes is attributable to their effects on blood pressure?
    Statistics in medicine, 2013, Feb-28, Volume: 32, Issue:5

    Topics: Amlodipine; Antihypertensive Agents; Biostatistics; Blood Pressure; Cardiovascular Diseases; Chlorthalidone; Coronary Disease; Endpoint Determination; Heart Failure; Humans; Hypertension; Lisinopril; Myocardial Infarction; Randomized Controlled Trials as Topic; Regression Analysis; Treatment Outcome

2013
Lessons from a patient with Turner syndrome.
    QJM : monthly journal of the Association of Physicians, 2013, Volume: 106, Issue:8

    Topics: Amlodipine; Blood Pressure; Chlorthalidone; Estrogens; Female; Hormone Replacement Therapy; Humans; Hypertension; Life Expectancy; Progestins; Turner Syndrome; Young Adult

2013
Pharmacogenetic effects of 'candidate gene complexes' on stroke in the GenHAT study.
    Pharmacogenetics and genomics, 2014, Volume: 24, Issue:11

    Topics: Aged; Amlodipine; Chlorthalidone; Female; Genotype; Humans; Lisinopril; Male; Middle Aged; Pharmacogenetics; Polymorphism, Single Nucleotide; Stroke

2014
Visit-to-Visit Variability of BP and CKD Outcomes: Results from the ALLHAT.
    Clinical journal of the American Society of Nephrology : CJASN, 2016, Mar-07, Volume: 11, Issue:3

    Topics: Aged; Amlodipine; Antihyperkalemic Agents; Blood Pressure; Blood Pressure Determination; Chlorthalidone; Disease Progression; Female; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Kidney Failure, Chronic; Lisinopril; Male; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Proportional Hazards Models; Randomized Controlled Trials as Topic; Renal Insufficiency, Chronic; Risk Factors; Time Factors; Treatment Outcome

2016
Antihypertensive drug use in resistant and nonresistant hypertension and in controlled and uncontrolled resistant hypertension.
    Journal of hypertension, 2018, Volume: 36, Issue:7

    Topics: Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Bisoprolol; Blood Pressure; Calcium Channel Blockers; Chlorthalidone; Diuretics; Drug Resistance; Drug Therapy, Combination; Humans; Hypertension; Imidazoles; Mineralocorticoid Receptor Antagonists; Ramipril; Tetrazoles

2018
Effects of Antihypertensive Class on Falls, Syncope, and Orthostatic Hypotension in Older Adults: The ALLHAT Trial.
    Hypertension (Dallas, Tex. : 1979), 2019, Volume: 74, Issue:4

    Topics: Accidental Falls; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Atenolol; Chlorthalidone; Female; Humans; Hypertension; Hypotension, Orthostatic; Incidence; Male; Medicare; Syncope; Treatment Outcome; United States

2019
QbD-based development of an extraction procedure for simultaneous quantification of telmisartan, amlodipine besylate and chlorthalidone in combination complex matrix formulation.
    Biomedical chromatography : BMC, 2020, Volume: 34, Issue:2

    Topics: Amlodipine; Chlorthalidone; Chromatography, High Pressure Liquid; Drug Combinations; Limit of Detection; Linear Models; Reproducibility of Results; Research Design; Tablets; Telmisartan

2020
The effects of antihypertensive class on gout in older adults: secondary analysis of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial.
    Journal of hypertension, 2020, Volume: 38, Issue:5

    Topics: Aged; Amlodipine; Antihypertensive Agents; Atenolol; Blood Pressure; Chlorthalidone; Female; Gout; Humans; Hypertension; Lisinopril; Male; Middle Aged; Myocardial Infarction; Treatment Outcome

2020
Contributions of Systolic and Diastolic Blood Pressures to Cardiovascular Outcomes in the ALLHAT Study.
    Journal of the American College of Cardiology, 2021, 10-26, Volume: 78, Issue:17

    Topics: Aged; Amlodipine; Blood Pressure; Blood Pressure Determination; Cardiovascular Diseases; Chlorthalidone; Diastole; Female; Follow-Up Studies; Heart Failure; Humans; Lisinopril; Male; Middle Aged; Myocardial Infarction; Proportional Hazards Models; Randomized Controlled Trials as Topic; Retrospective Studies; Risk; Risk Assessment; Risk Factors; Stroke; Systole

2021
Simultaneous Estimation of Telmisartan, Chlorthalidone, Amlodipine Besylate and Atorvastatin by RP-HPLC Method for Synchronous Assay of Multiple FDC Products Using Analytical FMCEA-Based AQbD Approach.
    Journal of chromatographic science, 2023, Feb-03, Volume: 61, Issue:2

    Topics: Amlodipine; Atorvastatin; Chlorthalidone; Chromatography, High Pressure Liquid; Telmisartan

2023
Choice of antihypertensive agent in isolated systolic hypertension and isolated diastolic hypertension: A secondary analysis of the ALLHAT trial.
    American heart journal, 2022, Volume: 254

    Topics: Amlodipine; Antihypertensive Agents; Chlorthalidone; Humans; Hypertension; Isolated Systolic Hypertension; Lisinopril; Treatment Outcome

2022
Financial implications of protocol-based hypertension treatment: an insight into medication costs in public and private health sectors in India.
    Journal of human hypertension, 2023, Volume: 37, Issue:9

    Topics: Amlodipine; Chlorthalidone; Humans; Hypertension; India; Private Sector; Telmisartan

2023