chlorthalidone and acebutolol

chlorthalidone has been researched along with acebutolol in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.14)18.7374
1990's4 (28.57)18.2507
2000's6 (42.86)29.6817
2010's3 (21.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Lombardo, F; Obach, RS; Waters, NJ1
Alimuddin, M; Bulloch, D; Dahl, R; Grant, D; Lee, N; Peacock, M1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Basciu, M; Cherchi, A; Pili, G; Sau, F; Seguro, C; Siddi, PP; Tamponi, R1
de Rezende, MC; Del Nero Júnior, E; Lima, EV; Savioli, RM1
Cutler, JA; Elmer, PJ; Flack, JM; Grandits, GA; Grimm, RH; McDonald, R; Neaton, JD; Prineas, RJ; Schoenberger, JA; Stamler, J1
Elmer, PJ; Flack, J; Grandits, A; Lewis, CE; McDonald, R1
Elmer, PJ; Flack, JM; Grandits, GA; Grimm, RH; Lewis, CE; Liebson, PR; McDonald, RH; Prineas, RJ; Svendsen, K; Yunis, C1

Reviews

1 review(s) available for chlorthalidone and acebutolol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

5 trial(s) available for chlorthalidone and acebutolol

ArticleYear
[Electrocardiographic and echocardiographic changes during antihypertensive therapy].
    Cardiologia (Rome, Italy), 1990, Volume: 35, Issue:12

    Topics: Acebutolol; Adolescent; Adult; Aged; Antihypertensive Agents; Captopril; Cardiomegaly; Chlorthalidone; Echocardiography; Electrocardiography; Female; Humans; Hypertension; Indenes; Male; Middle Aged; Nifedipine; Oxprenolol; Pindolol; Propanolamines; Timolol

1990
[Evaluation of the antihypertensive efficacy of acebutolol, chlorthalidone and the combination of acebutolol and chlorthalidone in the treatment of mild and moderate primary arterial hypertension].
    Arquivos brasileiros de cardiologia, 1983, Volume: 40, Issue:5

    Topics: Acebutolol; Adult; Blood Pressure; Chlorthalidone; Clinical Trials as Topic; Drug Combinations; Female; Humans; Hypertension; Male; Middle Aged; Potassium; Uric Acid

1983
Treatment of Mild Hypertension Study. Final results. Treatment of Mild Hypertension Study Research Group.
    JAMA, 1993, Aug-11, Volume: 270, Issue:6

    Topics: Acebutolol; Aged; Amlodipine; Antihypertensive Agents; Chlorthalidone; Diastole; Double-Blind Method; Doxazosin; Echocardiography; Electrocardiography; Enalapril; Exercise; Female; Follow-Up Studies; Health Behavior; Humans; Hypertension; Long-Term Care; Male; Middle Aged; Treatment Outcome

1993
Efficacy and tolerance of antihypertensive treatment in men and women with stage 1 diastolic hypertension. Results of the Treatment of Mild Hypertension Study.
    Archives of internal medicine, 1996, Feb-26, Volume: 156, Issue:4

    Topics: Acebutolol; Aged; Amlodipine; Antihypertensive Agents; Chlorthalidone; Doxazosin; Enalapril; Female; Humans; Hygiene; Hypertension; Life Style; Male; Middle Aged; Nutritional Physiological Phenomena; Patient Education as Topic; Severity of Illness Index; Treatment Outcome

1996
Long-term effects on sexual function of five antihypertensive drugs and nutritional hygienic treatment in hypertensive men and women. Treatment of Mild Hypertension Study (TOMHS)
    Hypertension (Dallas, Tex. : 1979), 1997, Volume: 29, Issue:1 Pt 1

    Topics: Acebutolol; Aged; Amlodipine; Antihypertensive Agents; Chlorthalidone; Double-Blind Method; Doxazosin; Enalapril; Female; Humans; Hypertension; Libido; Male; Middle Aged; Orgasm; Penile Erection; Sexual Dysfunction, Physiological

1997

Other Studies

8 other study(ies) available for chlorthalidone and acebutolol

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Determination of log D via automated microfluidic liquid-liquid extraction.
    Journal of medicinal chemistry, 2008, Aug-28, Volume: 51, Issue:16

    Topics: Automation; Biopharmaceutics; Microfluidic Analytical Techniques; Pharmacokinetics

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010