chlorpropamide has been researched along with tolbutamide in 387 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 343 (88.63) | 18.7374 |
| 1990's | 10 (2.58) | 18.2507 |
| 2000's | 12 (3.10) | 29.6817 |
| 2010's | 18 (4.65) | 24.3611 |
| 2020's | 4 (1.03) | 2.80 |
| Authors | Studies |
|---|---|
| Hashimoto, Y; Inui, K; Saito, H; Sawada, K; Terada, T | 1 |
| Hashimoto, Y; Inui, K; Saito, H; Uwai, Y | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Anacardio, R; Aureli, L; Cesta, MC; Cruciani, G; De Simone, L; Moriconi, A | 1 |
| Ekins, S; Harwood, HJ; Hoover, DJ; Lawton, MP; Mankowski, DC; Treadway, JL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Buttar, D; Colclough, N; Gerhardt, S; MacFaul, PA; Maskos, K; Phillips, SD; Plowright, A; Steinbacher, S; Steuber, H; Tam, K; Whittamore, P | 1 |
| Kouznetsova, VL; Nagle, MA; Nigam, SK; Tsigelny, IF | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Bending, MR; Dollery, CT; Kahn, GC; Mucklow, JC | 1 |
| Melander, A; Wåhlin-Boll, E | 2 |
| Child, JJ; Haskins, RH | 1 |
| Balant, L | 1 |
| Haslbeck, M | 1 |
| Macchi, IA; Zeytinoğlu, FN | 1 |
| Handler, JS; Keiser, HR; Zusman, RM | 1 |
| Levey, GS | 1 |
| Cloutier, MC; Crowther, RL; Fajans, SS | 1 |
| Foy, JM; Lucas, PD | 1 |
| Bressler, R; Shen, SW | 2 |
| Friedberg, SJ; Kudzma, DJ | 1 |
| Bradley, RF; Gleason, RE; Graham, CA; Soeldner, JS; Tan, MH | 1 |
| Christensen, LK; Hansen, JM | 1 |
| Bloom, A; Bulpitt, CJ; Shaw, KM | 1 |
| Jorgensen, KD | 1 |
| Di Saverio, S; Roncaia, R; Torri, A; Zanni, A | 1 |
| Balant, L; Fabre, J; Loutan, L; Samimi, H; Tillolès, M | 1 |
| Butterfield, AG; Kolasinski, H; Lovering, EG; Matsui, FF; Robertson, DL | 1 |
| Milman, HA; Peckham, JC; Tarone, RE; Ward, JM | 1 |
| Ichibagase, H; Imamura, Y; Suenaga, A; Teramoto, M; Yamaguchi, T | 1 |
| Bitzén, PO; Melander, A; Sartor, G; Scherstén, B; Wåhlin, E | 1 |
| Crechiolo, J; Hill, RE | 1 |
| Eshelman, FN | 1 |
| Angelini, G; Meneghini, CL | 1 |
| García, JM; Herrera, J; Molina, J | 1 |
| Field, JB; Schmeltz, R; Wendorff, HJ | 1 |
| Bandisode, MS; Boshell, BR | 1 |
| Streda, M | 1 |
| Shagan, BP | 1 |
| Bennett, MA; Fitzgerald, MG; Malins, JM; Pentecost, BL; Soler, NG | 1 |
| Ogawa, S; Yoshinaga, T | 1 |
| Andreev, D; Pampulov, L | 1 |
| Müller, WE; Wollert, U | 1 |
| Brown, KF; Crooks, MJ | 3 |
| Bransome, ED; Braselton, WE; Huff, TA | 1 |
| Bohannon, NV; Dunphy, TW; Forsham, PH; Gerich, JE; Kane, JP; Karam, JH; Lorenzi, M; Tsalikian, E | 1 |
| Herrera, J; Molina, J; Sabater, J | 1 |
| Beaudoin, N; McGilveray, IJ; Sved, S | 1 |
| Awang, DV; McGilveray, IJ; Midha, KK | 1 |
| Brearley, BF | 1 |
| Daintith, H; O'Malley, K; Stevenson, IH | 1 |
| Charette, C; McGilveray, IJ; Midha, KK | 1 |
| Kivistö, KT; Neuvonen, PJ | 1 |
| Harrower, AD | 1 |
| Boutagy, JS; Shenfield, GM; Webb, C | 1 |
| Dakas, CJ; Takla, PG | 1 |
| Cabello, MA; Felíu, JE; Monge, L; Ortega, JL; Samper, B | 1 |
| Berliński, E; Horoszek-Maziarz, S; Jaromczyk-Slisz, J; Krupa-Wojciechowska, B; Orłowska-Kunikowska, E; Rachoń, K; Słomiński, M; Wójcikowski, C | 1 |
| Colombo, R; Pinelli, A; Tofanetti, O; Trivulzio, S; Zecca, L | 1 |
| Hatao, K; Kaku, K; Kaneko, T; Matsuda, M; Tsuchiya, M | 1 |
| Little, RG; Petersen, DR | 1 |
| Ser, I | 1 |
| Judis, J | 2 |
| Ravina, A | 1 |
| Barnes, AJ; Bloom, A; Crowley, MF; Garbien, KJ | 1 |
| Notelovitz, M | 3 |
| Matin, SB; Rowland, M | 1 |
| Butterfield, WJ; Whichelow, MJ | 1 |
| Christensen, LK; Kristensen, M | 1 |
| Fabre, J; Petitpierre, B | 1 |
| De Matteis, F | 2 |
| Jackson, WP; Keller, P; Van Mieghem, W | 1 |
| Foy, JM; Standing, VF | 1 |
| Daweke, H; Fähndrich, W; Liebermeister, H; Schmitt, H | 1 |
| Stowers, JM | 1 |
| de Baere, H; de Leeuw, I; Decraene, P; Lemmens, P; Verhaegen, H | 1 |
| Goodner, CJ; Ogilvie, JT | 1 |
| Hsu, PL; Luzzi, LA; Ma, JK | 1 |
| Scoville, AB | 1 |
| Kar, BC; Panda, NC; Parija, CR; Tej, SC; Tripathy, BB | 1 |
| Hasselblatt, A; Panten, U; Poser, W; Schönborn, J | 1 |
| Mughini, L; Polosa, P | 1 |
| Bavel'skii, ZE; Kuts, LG; Lazaris, YA | 1 |
| Aziz, MT; Einen, MA; el-Ebrashy, N; Higazi, AM; Mashaly, M | 1 |
| Kroneberg, G; Puls, W | 1 |
| Hüthwohl, B; Jähnchen, E | 1 |
| De Schepper, PJ; Debeer, L; Mannaerts, G | 1 |
| Nakajima, I | 1 |
| Goodman, AD; Mahoney, JH | 1 |
| Brooker, G; Fichman, M | 1 |
| Ando, A; Orita, Y; Shirai, D; Takamitsu, Y; Urakabe, S | 2 |
| Augusti, KT; Kurup, PA | 1 |
| Shenkman, L | 1 |
| Lasseter, KC; Levey, GS; McCarthy, JS; Palmer, RF | 1 |
| Felber, JP | 1 |
| Lasseter, KC; Levey, GS; Palmer, RF | 1 |
| Dempsey, ME | 1 |
| Ariëns, EJ | 1 |
| Prescott, LF; Redman, DR | 1 |
| Agren, A; Nilsson, B | 1 |
| Berger, W; Collard, F; Denes, A; Girard, J; Göschke, H | 1 |
| Jounela, AJ; Palva, IP; Pirttiaho, H | 1 |
| Wosilait, WD | 1 |
| Curchod, B | 1 |
| Canaani, Z | 2 |
| Stehling, L | 1 |
| Miller, M; Moses, AM | 1 |
| Bird, GW; Eeles, GH; Litchfield, JA; Rahman, M; Wingham, J | 1 |
| Parodi, FA | 1 |
| Mitra, D; Mutalik, GS; Nayak, NJ; Oak, VR | 1 |
| Seltzer, HS | 1 |
| Bloom, A | 1 |
| Favarger, P; Gonçalves, J; Rous, S | 1 |
| Fajans, SS | 1 |
| DeLawter, DE; Moss, JM | 1 |
| Mulder, G; Thurkow, I; Wesseling, H | 1 |
| Aggarwal, V; Sunshine, I | 1 |
| Rojszykowa, E; Wrzesimski, W | 1 |
| Mehnert, H | 1 |
| Klyś, J; Mikosz, R; Wasowicz, Z | 1 |
| Fidel, J; Nelken, L | 1 |
| Canivet, J; Mantel, O | 1 |
| Beaser, SB; Macchi, IA | 1 |
| Chhetri, MK | 1 |
| Morita, T; Yawata, M | 1 |
| Loubatières, AL | 1 |
| Martin, E | 1 |
| Jackson, WP; Vinik, AI | 1 |
| Seftel, HC | 1 |
| Lopis, S; Schneider, T | 1 |
| Pfaff, W; Schöne, HH | 1 |
| Bänder, A; Pfaff, W; Schesmer, G | 1 |
| Kadota, I | 1 |
| Creutzfeldt, W | 1 |
| Dangoumau, J; Traissac, FJ | 1 |
| Böninger, C; Sauer, H | 1 |
| Jackson, WP | 1 |
| Bricker, LA; Mintz, DH | 1 |
| Colwell, JA; Craane, TJ; Hershman, JM | 1 |
| Zgliczyński, S | 1 |
| Sigroth, K; Steen, B; Svanborg, A | 1 |
| Creutzfeldt, W; Scheler, F; Wigger, W | 1 |
| Clarke, BF; Duncan, LJ | 1 |
| Consiglio, D; Hopps, V; Mantia, G | 1 |
| Bhattia, SK; Hadden, DR; Montgomery, DA; Weaver, JA | 1 |
| Basabe, JC; Chieri, RA; Farina, JM; Foglia, VG | 1 |
| Bloom, A; Tomkins, AM | 1 |
| Conn, JW; Fajans, SS; Floyd, JC; Knopf, RF; Pek, S | 1 |
| Meijer, DK; Thürkow, I; Wesseling, H | 1 |
| Gulbenkian, A; Ornstein, L; Tabachnick, II | 1 |
| Martin, FI; Stocks, AE | 1 |
| Elkeles, RS | 1 |
| Alliende, ME; Artega, A; Eyzaguirre, J; Foradori, A; Soto, S | 1 |
| Harris, EL | 1 |
| Bianchini, P; Bramanti, G; De Fina, V; Dell'Omodarme, G | 1 |
| Ahuja, MM; Kumar, V | 1 |
| Berger, W | 1 |
| Sato, A | 1 |
| Fraser, TR; Wales, JK | 1 |
| Chakrabarti, R; Evans, J; Fearnley, GR; Hocking, ED | 1 |
| Bissel, G; Katz, HM | 1 |
| Pereira, VG; Pupo, AA; Wajchenberg, BL | 1 |
| Brooks, AM; Grinnell, EH; Skillman, TG | 1 |
| Hurwitz, D; Singer, DL | 1 |
| Bonardi, G; Coppi, G | 1 |
| Dixon, RL; Lockwood, RR | 1 |
| Kawakami, F; Nishikawa, M; Ohara, T; Tarui, S | 1 |
| Bänder, A; Pfaff, W; Schmidt, FH; Schröder, HG; Stork, H | 1 |
| Alhan, MA; Arinik, A; Berker, F; Cakirgöz, C; Oner, M; Sandalci, O | 1 |
| Danelon-Martina, L | 1 |
| Sabih, K | 1 |
| De la Revilla, L; Estella, F; García Torres, JA; Gutiérrez, J; Peña, JF; Rosales, G | 1 |
| Camerini-Dávalos, RA; De Lellis, RH; Jimenez, JA; Oppermann, W | 1 |
| Accettella, U; Gentile, M; Sacra, A | 1 |
| Frawley, TF; Hagen, GA | 1 |
| McDonald, HJ; Murray, HL | 1 |
| Biron, A; Burguburu, AM; de Serre, S; Gharib, C; Rivet, O; Sassard, J | 1 |
| Berger, W; Spring, P | 1 |
| Mpliatis, A; Schricker, KT | 1 |
| Dhirawani, MK; Doshi, JC; Patel, JC | 1 |
| Rojszykowa, E | 1 |
| Cabili, S; Ravid, M; Rubinstein, E | 1 |
| Bruns, W; Michaelis, D; Wappler, E | 1 |
| Heisig, N | 1 |
| Fog-Moller, F; Nistrup Madsen, S; Persson, I | 1 |
| Gulati, OD; Patel, DG | 1 |
| Gupta, NN; Kumar, D; Mehrotra, RM | 1 |
| Anantnarayanan, KG; Khurana, U; Panse, MV | 1 |
| Kaeding, A; Werner, P | 1 |
| Arsenić, E | 1 |
| Hershman, JM; Konerding, K | 1 |
| Fineberg, SK | 3 |
| Bittles, AH; Hadden, DR; Montgomery, DA; Rigas, AN | 1 |
| Bressler, R; Podgainy, H | 1 |
| Bergmann, F; Gutman, Y; Zerachia, A | 1 |
| Schulz, E | 1 |
| Cristiano, L; Sgambato, S; Torella, R | 1 |
| Beck, H; Vignalou, J | 1 |
| Parrow, A | 1 |
| Luethi, A; Studer, H | 1 |
| DeChatelet, LR; McDonald, HJ | 2 |
| Abelove, WA; Echenique, R | 1 |
| Goto, Y; Kikuchi, J; Oneda, A; Toyota, T; Yamagata, S | 1 |
| Bänder, A; Noetzel, G; Vogel, HG | 1 |
| Fearnley, GR | 2 |
| Goodman, JI | 3 |
| Khachadurian, AK; Somerville, I | 1 |
| Fabián, D; Kmoch, J; Sieberová, R; Svoboda, Z | 1 |
| Berglund, B; Jakobson, T | 1 |
| Clarke, BF; Duncan, LJ; Munro, JF | 1 |
| Conason, EG; Most, S; Podolsky, S; Rifkin, H; Ross, H | 1 |
| Ellenberg, M | 1 |
| Dube, BK; Kumar, A | 1 |
| Howells, L; Powell, T | 1 |
| Penttilä, IM | 1 |
| Kawerau, E; Surtees, SJ | 1 |
| Börner, H; Schulz, E | 1 |
| Howard, T; Kinsell, LW; McMasters, V; Olcott, HS; van der Veen, J | 1 |
| Gershbein, LL | 1 |
| Sussman, KE | 1 |
| De Schepper, PJ | 1 |
| De Beer, L; De Schepper, PJ | 1 |
| Fisher, AA | 1 |
| Hellman, B; Sehlin, J; Täljedal, IB | 1 |
| Alberetto, M; Baio, G; Bertoletti, A; Pontiroli, AE; Pozza, G | 1 |
| Tattersall, RB | 1 |
| Hjelle, JJ; Petersen, DR | 1 |
| Melander, A; Sartor, G; Scherstén, B; Wåhlin-Boll, E | 3 |
| Feldman, JM; Skillman, TG | 1 |
| Butturini, U; Capretti, L; Coscelli, C; Girone, M; Rocca, G; Speroni, G | 1 |
| Papouchado, M; Reed, PI; Thornton, PC | 1 |
| Meyer, MC; Raghow, G | 1 |
| Galasky, SP; Leichter, SB | 1 |
| Crowson, TW; Kriel, RL | 1 |
| Higashiyama, K; Nagai, T; Ueda, H | 1 |
| Dreyer, M; Kühnau, J; Rüdiger, HW | 1 |
| Elliott, BD; Johnson, R; Langer, O; Prihoda, T; Schenker, S | 1 |
| Brown, MB; Fajans, SS | 1 |
| Birkett, DJ; Miners, JO | 1 |
| Selvaag, E | 1 |
| Akita, H; Imamura, Y; Koga, T; Migita, T; Nozawa, M; Otagiri, M; Ryu, A | 1 |
| Abenhaim, L; Monette, J; van Staa, T | 1 |
| Ikeda, T; Ochi, H | 1 |
| Galli Kienle, M; Magni, F; Marazzini, L; Monti, L; Pereira, S | 1 |
| McCAMPBELL, SR; WEST, KM | 1 |
| BOSHELL, BR; JEANRENAUD, B; RENOLD, AE; ZAHND, GR | 1 |
| CRAIG, JW; MILLER, M; MILLS, FD; NICKERSON, N | 1 |
| SUGAR, SJ; THOMAS, LJ | 1 |
| CHARIF, BS; SEGARRA, FO; SHERMAN, DS | 1 |
| DOROSIN, DE; FORSHAM, PH; MAGID, GJ | 1 |
| HEINSEN, HA | 1 |
| EVANS, EC; FERRIS, HA; HAMFF, LH; WHITEMAN, HW | 1 |
| BLOCH, J; LENHARDT, A | 1 |
| DANOWSKI, TS; MATEER, FM | 1 |
| JOHNSON, PC; WEST, KM | 1 |
| IZZO, JL | 1 |
| OWEN, JA | 1 |
| PEDRANZINI, F | 1 |
| LEVITT, LM | 1 |
| BLOECH, J; LENHARDT, A | 1 |
| BRATFOS, O; FLATTEN, O; SAGEDAL, E | 1 |
| CRAIG, JW; MILLER, M; MILLS, FD | 1 |
| ELLIOT, A; GRONBERG, A | 1 |
| COLAJANNI, L; GIULIANO, G | 1 |
| HERMAN, JB; JACKSON, WP | 1 |
| HERNANDEZ JAUREGUI, R | 1 |
| BLUMSOHN, D; CAMPBELL, GD; JACKSON, WP; NOTELOVITZ, M | 1 |
| BUSTOS FERNANDEZ, L; DE PAULA, A; JADZINSKY, MN; NUSIMOVICH, B; POGORELSKY, C | 1 |
| BALLARD, BE; NELSON, E | 1 |
| SADOW, HS | 1 |
| BELLET, S; FEINBERG, LJ; GAGNON, F; GELBER, L; MULLER, O; SANDBERG, H | 1 |
| TULLOCH, J | 1 |
| GLASSER, EJ; PERKAL, S; WISHINSKY, H | 1 |
| AHUJA, MM | 1 |
| CALVERT, DN | 1 |
| CUSHMAN, P; DUBOIS, JJ; DWYER, E; IZZO, JL | 1 |
| DEROETTH, A; PEI, YF | 1 |
| NABARRO, JD | 1 |
| KEELEY, KJ; SEFTEL, HC | 1 |
| FORBES, JI; GELFAND, M | 1 |
| OHNEDA, A; YAMAGATA, S | 1 |
| DENEUMANN, PS | 1 |
| LAZARUS, SS; VOLK, BW; WELLMAN, KF | 1 |
| POULSEN, JE | 1 |
| BEASER, SB | 1 |
| YOSHIDA, R | 1 |
| LOPEZFERNANDEZ, RJ | 1 |
| TRANQUADA, RE | 1 |
| MONTGOMERY, DA; RASTOGI, GK; WEAVER, JA | 1 |
| ALRIC, R; FRUTEAUDELACLOS, C; HOUAREAU, MH; LOUBATIERES, A | 1 |
| SZANTO, S | 1 |
| PADFIELD, CJ | 1 |
| MOLNAR, Z; VARGA, F | 1 |
| WELLER, C | 1 |
| CAGLI, V | 1 |
| CAMERINI D AVALOS, RA; KRALL, LP; LOZANO CASTANEDA, O; MARBLE, A | 1 |
| ALTERMAN, SL; LIEBER, AL | 1 |
| CHAKRABARTI, R; FEARNLEY, GR | 2 |
| CANTERA, N; CIAMMAICHELLA, A | 1 |
| MCKINLEY, RA; MOORHEAD, HH | 1 |
| COOKE, AM; FITZGERALD, MG; MALINS, JM; PYKE, DA | 1 |
| ERSLEV, AJ | 1 |
| CHANIS, RA | 1 |
| ELMOFTY, AM | 1 |
| ALVARINAS, CE; BARONLIS, E; LEMOSGARCIA, M; PRESS, L | 1 |
| ARNOLD, CR; LAUENER, RW | 1 |
| LANGDON, RG; WOLFF, FW | 1 |
| DALLECOSTE, P; KLINGER, R | 1 |
| HERMAN, M; JACKSON, WP | 1 |
| DELAWTER, DE; GALLAGHER, EJ; MOSS, JM | 1 |
| WILENSKY, AS | 1 |
| BALL, JE; ELLIOT, W; LUPIN, AM; MARY, CC | 1 |
| BARSE, R; GRINNELL, EH; MOLLER, CL; SKILLMAN, TG | 1 |
| GROENBERG, A; OSTMAN, J | 1 |
| MARQUES, M; RIETCORREA, P | 1 |
| Brown, JD; Stone, DB | 1 |
| ANGELI, I | 1 |
| ROWE, WS | 1 |
| KODEJSZKO, E | 1 |
| BATEMAN, M; BLOOM, A; NEWTON, MA | 1 |
| HORN, Z | 1 |
| HAUPTMANN, E; MICULINIC, R | 1 |
| KEEN, H | 1 |
| BAUER, HG | 1 |
| FORIST, AA; SMITH, DL; VECCHIO, TJ | 1 |
| COLLENS, WS; DOBKIN, GB | 1 |
| BERGMAN, H | 1 |
| KERR, JH; TITTLE, CR | 1 |
| ANDERSON, J; SHELDON, J; STONER, L | 1 |
| FERGUSON, BD | 1 |
| KAR, BC; TRIPATHY, BB | 1 |
| BERKOW, JW; RICKETTS, RL | 1 |
| WILLIAMS, RH | 1 |
| HUNTON, RB; SKIPPER, EW; WELLS, MV | 1 |
| MORGENSTERN, LL | 1 |
| Heinänen, P; Koivisto, M; Lehto, VP; Tanninen, VP | 1 |
| Fatehi, M; Lang, VY; Light, PE | 1 |
| Friščić, T; Mottillo, C; Štrukil, V; Tan, D | 1 |
| Mitra, S; Singh, IR | 1 |
| Glatz, Z; Michalcová, L; Nevídalová, H | 1 |
| Bookwala, M; Buckner, IS; Wildfong, PLD | 1 |
| Jannetto, PJ; Langman, LJ | 1 |
35 review(s) available for chlorpropamide and tolbutamide
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
["First" and "second" generation sulfonylureas: distinction or difference? (author's transl)].
Topics: Animals; Chlorpropamide; Dose-Response Relationship, Drug; Glipizide; Glyburide; Half-Life; Humans; Hypoglycemic Agents; Kinetics; Structure-Activity Relationship; Sulfonylurea Compounds; Tolbutamide | 1978 |
[New aspects of therapy with oral antidiabetic agents].
Topics: Acidosis; Biguanides; Blood Proteins; Chlorpropamide; Diabetes Mellitus; Diabetic Nephropathies; Drug Interactions; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Protein Binding; Sulfonamides; Sulfonylurea Compounds; Tolbutamide | 1979 |
Clinical and etiological heterogeneity of idiopathic diabetes mellitus. The banting memorial lecture.
Topics: Adenoma, Islet Cell; Adult; Antibodies, Viral; Autoantibodies; Cell Adhesion; Chlorpropamide; Chromosome Aberrations; Chromosome Disorders; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diseases in Twins; Female; Glucose; Glucose Tolerance Test; Histocompatibility Antigens; Humans; Hyperglycemia; Insulin; Islets of Langerhans; Ketosis; Lymphocytes; Male; Pedigree; Tolbutamide | 1979 |
Clinical pharmacology of oral antidiabetic agents (first of two parts).
Topics: Acetohexamide; Administration, Oral; Chemical Phenomena; Chemistry; Chlorpropamide; Diabetes Mellitus; Drug Evaluation; Drug Interactions; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Lipid Metabolism; Phenformin; Secretory Rate; Tolazamide; Tolbutamide | 1977 |
Clinical pharmacology of oral antidiabetic agents (second of two parts).
Topics: Administration, Oral; Cardiovascular Diseases; Chlorpropamide; Clinical Trials as Topic; Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Islets of Langerhans; Phenformin; Tolbutamide; Water Intoxication | 1977 |
Drug interactions with oral sulphonylurea hypoglycaemic drugs.
Topics: Allopurinol; Analgesics; Anticoagulants; Chloramphenicol; Chlorpropamide; Disulfiram; Drug Interactions; Ethanol; Glyburide; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Kinetics; Monoamine Oxidase Inhibitors; Novobiocin; Phenylbutazone; Phenytoin; Probenecid; Propranolol; Rifampin; Sulfonamides; Sulfonylurea Compounds; Tolbutamide | 1977 |
Glucose tolerance tests in the clinical picture of chronic liver diseases.
Topics: Adolescent; Adult; Age Factors; Aged; Alanine Transaminase; Aspartate Aminotransferases; Body Weight; Carbohydrate Metabolism; Chlorpropamide; Chronic Disease; Glucose Tolerance Test; Hepatitis; Humans; Hydrocortisone; Hypoglycemic Agents; Jaundice; Liver; Liver Cirrhosis; Liver Diseases; Metformin; Middle Aged; Porphyrias; Tolbutamide | 1975 |
Diabetes in the elderly patient.
Topics: Acetohexamide; Aged; Chlorpropamide; Diabetes Mellitus; Diet, Diabetic; Energy Intake; Foot; Health Education; Humans; Hygiene; Hypoglycemic Agents; Insulin; Phenformin; Sulfonylurea Compounds; Tolbutamide | 1976 |
Toxic hepatic porphyrias.
Topics: Alcoholism; Antifungal Agents; Chemical and Drug Induced Liver Injury; Chlorpropamide; Hexachlorocyclohexane; Humans; Liver; Phenobarbital; Phenytoin; Porphyrias; Sulfanilamides; Sulfones; Tolbutamide; Turkey | 1968 |
Oral treatment in diabetes.
Topics: Acetohexamide; Acidosis; Administration, Oral; Animals; Biguanides; Cardiovascular Diseases; Chlorpropamide; Diabetes Complications; Diabetes Mellitus; Glyburide; Humans; Hypoglycemia; Liver; Obesity; Structure-Activity Relationship; Sulfonylurea Compounds; Tolazamide; Tolbutamide | 1972 |
Sulfonylureas and the heart.
Topics: Adenylyl Cyclases; Animals; Cats; Chlorpropamide; Coronary Circulation; Cyclic AMP; Diabetes Mellitus; Enzyme Activation; Heart; Heart Rate; Humans; Kidney; Myocardium; Norepinephrine; Oxygen Consumption; Phenformin; Phosphoric Diester Hydrolases; Rabbits; Rats; Species Specificity; Stimulation, Chemical; Sulfonylurea Compounds; Tolbutamide | 1974 |
[Oral antidiabetics. Dose, plasma concentration and effect].
Topics: Acetohexamide; Adrenergic beta-Antagonists; Animals; Blood Glucose; Carbutamide; Chemical Phenomena; Chemistry; Chlorpropamide; Cyclic AMP; Diazoxide; Drug Antagonism; Drug Synergism; Glucagon; Glucose; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Isoproterenol; Kidney; Liver; Sulfonamides; Sulfonylurea Compounds; Theophylline; Tolbutamide | 1969 |
[Side-effects of oral antidiabetic drugs].
Topics: Administration, Oral; Biguanides; Chlorpropamide; Humans; Hypoglycemic Agents; Time Factors; Tolbutamide | 1972 |
Hypoglycemic drugs.
Topics: Acetohexamide; Anesthetics; Blood Glucose; Carbohydrate Metabolism; Chlorpropamide; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Neuropathies; Gastrointestinal Diseases; Humans; Hypoglycemic Agents; Insulin; Islets of Langerhans; Pancreas; Phenformin; Tolazamide; Tolbutamide | 1974 |
Drug-induced dilutional hyponatremia.
Topics: Acetaminophen; Amitriptyline; Animals; Anura; Body Fluids; Carbamazepine; Chlorpropamide; Clofibrate; Cyclophosphamide; Diabetes Insipidus; Diabetes Mellitus; Diazoxide; Drug-Related Side Effects and Adverse Reactions; Humans; Hypoglycemic Agents; Hyponatremia; Kidney; Rats; Sodium; Sulfonylurea Compounds; Tolbutamide; Urinary Bladder; Vasopressins; Vincristine; Water Intoxication; Water-Electrolyte Balance | 1974 |
Drug-induced hypoglycemia. A review based on 473 cases.
Topics: Acetohexamide; Adolescent; Adult; Aminobenzoates; Child; Child, Preschool; Chlorpropamide; Coma; Edetic Acid; Ethanol; Female; Humans; Hypoglycemia; Hypoglycemic Agents; Infant; Infant, Newborn; Insulin; Male; Manganese; Middle Aged; Nutritional Physiological Phenomena; Oxytetracycline; Propranolol; Salicylates; Sulfonylurea Compounds; Tolbutamide | 1972 |
[Hypoglycemic coma of antidiabetic sulfamides].
Topics: Acetohexamide; Adolescent; Adult; Aged; Carbutamide; Child; Child, Preschool; Chlorpropamide; Diabetic Coma; Female; Humans; Hypoglycemia; Hypoglycemic Agents; Male; Middle Aged; Tolbutamide | 1967 |
Disturbances of liver porphyrin metabolism caused by drugs.
Topics: Animals; Chlorpropamide; Drug-Related Side Effects and Adverse Reactions; Estrogens; Griseofulvin; Humans; Hypnotics and Sedatives; Liver; Mice; Phenobarbital; Porphyrias; Porphyrins; Rats; Sulfones; Tolbutamide | 1967 |
Oral treatment of diabetes mellitus.
Topics: Chlorpropamide; Diabetes Mellitus; Humans; Hypoglycemia; Hypoglycemic Agents; Metformin; Phenformin; Sulfonamides; Tolbutamide | 1968 |
[Side-effects of oral antidiabetics].
Topics: Acetohexamide; Biguanides; Carbutamide; Chemical Phenomena; Chemistry; Chlorpropamide; Humans; Hypoglycemic Agents; Thyroid Gland; Tolbutamide | 1968 |
[Hypoglycemic sulfonamides].
Topics: Acetohexamide; Animals; Blood Glucose; Carbutamide; Chlorpropamide; Dogs; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Organ Size; Pancreas; Rats; Stimulation, Chemical; Sulfonamides; Tolazamide; Tolbutamide | 1968 |
[Use of hypoglycemic sulfonamides in the clinic].
Topics: Acetohexamide; Adult; Carbutamide; Chlorpropamide; Diabetes Mellitus; Humans; Hypoglycemia; Hypoglycemic Agents; Sulfonamides; Tolbutamide | 1968 |
[Evaluation of therapy of diabetes mellitus, with special reference to the control of diabetes mellitus with oral antidiabetics].
Topics: Adult; Animals; Blood Glucose; Cattle; Chlorpropamide; Diabetes Complications; Diabetes Mellitus; Diabetic Retinopathy; Diet Therapy; Female; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Ketone Bodies; Male; Middle Aged; Phenformin; Swine; Tolbutamide | 1969 |
[Current views on the mode of action of hypoglycemic sulfonamides].
Topics: Amino Acids; Animals; Blood Glucose; Chlorpropamide; Diabetes Insipidus; Diabetes Mellitus, Experimental; Diuresis; Drug Synergism; Glucagon; Glucose; Glucose Tolerance Test; Humans; Hydrochlorothiazide; Hypoglycemic Agents; Injections, Intravenous; Insulin; Insulin Secretion; Liver; Rabbits; Rats; Sulfonamides; Tolbutamide | 1969 |
[Cytopenias caused by hypoglycemic sulfonamides].
Topics: Aged; Agranulocytosis; Anemia, Aplastic; Anemia, Hemolytic; Carbutamide; Chlorpropamide; Female; Humans; Hypersensitivity; Male; Middle Aged; Purpura, Thrombocytopenic; Sulfonamides; Tolbutamide | 1968 |
Oral sulphonylureas in the management of diabetes.
Topics: Acetohexamide; Chlorpropamide; Cyclohexanes; Diabetes Mellitus; Endocrine Glands; Glucose Tolerance Test; Humans; Hypoglycemia; Hypoglycemic Agents; Obesity; Pyrimidines; Sulfones; Sulfonic Acids; Tolazamide; Tolbutamide; Urea; Vascular Diseases | 1971 |
Insulin-independent diabetes mellitus.
Topics: Acetohexamide; Adult; Age Factors; Aged; Basement Membrane; Capillaries; Carbohydrate Metabolism, Inborn Errors; Chlorpropamide; Diabetes Complications; Diabetes Mellitus; Diet, Diabetic; Female; Glucose Tolerance Test; Humans; Hyperlipidemias; Hypoglycemic Agents; Infections; Male; Middle Aged; Muscles; Obesity; Phenformin; Skin Ulcer; Thigh; Tolazamide; Tolbutamide | 1971 |
Advances in the treatment of diabetes mellitus.
Topics: Blood Glucose; Chlorpropamide; Clofibrate; Diabetes Mellitus; Diabetic Coma; Diabetic Ketoacidosis; Diabetic Retinopathy; Diet Therapy; Humans; Hypoglycemia; Insulin; Kidney Transplantation; Lactates; Light Coagulation; Metformin; Methods; Pancreas Transplantation; Phenformin; Pituitary Gland; Renal Dialysis; Sulfonylurea Compounds; Tolbutamide | 1971 |
[25 years of diabetic treatment by oral hypoglycemic agents: successes and failures].
Topics: Aged; Aging; Blood Glucose; Cardiovascular Diseases; Chlorpropamide; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diet, Reducing; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Middle Aged; Phenformin; Sulfonylurea Compounds; Tolbutamide | 1984 |
ADVANCES IN THE TREATMENT OF DIABETES MELLITUS.
Topics: Chlorpropamide; Diabetes Mellitus; Humans; Hypoglycemic Agents; Insulin; Metformin; Phenformin; Tolbutamide | 1963 |
ALCOHOLISM.
Topics: Alcoholism; Chlordiazepoxide; Chlormethiazole; Chlorpropamide; Culture; Lysergic Acid Diethylamide; Magnesium Deficiency; Meprobamate; Mice; Promazine; Psychotherapy; Psychotherapy, Group; Rabbits; Research; Suggestion; Tolbutamide; Triiodothyronine | 1963 |
THE ACTION OF SULFONYLUREAS IN PRODUCING HYPOGLYCEMIA.
Topics: Carbutamide; Chlorpropamide; Hypoglycemia; Hypoglycemic Agents; Pharmacology; Sulfonylurea Compounds; Tolbutamide | 1964 |
[SIDE-EFFECTS IN THE ORAL TREATMENT OF DIABETES WITH SULFONYLUREAS].
Topics: Anemia; Anemia, Aplastic; Bone Marrow Diseases; Carbutamide; Chlorpropamide; Diabetes Mellitus; Hypoglycemia; Hypoglycemic Agents; Jaundice; Jaundice, Obstructive; Liver Diseases; Sulfonylurea Compounds; Tolbutamide; Toxicology | 1964 |
[THE MECHANISM OF ACTION OF PERORAL ANTIDIABETICS].
Topics: Biguanides; Carbutamide; Chlorpropamide; Humans; Hypoglycemic Agents; Liver Glycogen; Pharmacology; Tolbutamide | 1965 |
22 trial(s) available for chlorpropamide and tolbutamide
| Article | Year |
|---|---|
Clinical pharmacology of oral antidiabetic agents (second of two parts).
Topics: Administration, Oral; Cardiovascular Diseases; Chlorpropamide; Clinical Trials as Topic; Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Islets of Langerhans; Phenformin; Tolbutamide; Water Intoxication | 1977 |
Potentiation of hypoglycemic effect of chlorpropamide and phenfromin by halofenate.
Topics: Blood Glucose; Chlorpropamide; Clinical Trials as Topic; Clofibrate; Diabetes Mellitus; Drug Synergism; Glycolates; Halofenate; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Insulin; Phenformin; Tolazamide; Tolbutamide | 1977 |
The effects of long-term therapy with oral hypoglycemic agents on the oral glucose tolerance test dynamics in male chemical diabetics.
Topics: Acetohexamide; Administration, Oral; Adult; Blood Glucose; Chlorpropamide; Cholesterol; Clinical Trials as Topic; Diabetes Mellitus; Double-Blind Method; Female; Follow-Up Studies; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Phenformin; Placebos; Tolbutamide; Triglycerides | 1977 |
Clinical evaluation of a new sulfonylurea in maturity onset diabetes - glipizide (K-4024).
Topics: Adult; Aged; Chlorpropamide; Clinical Trials as Topic; Diabetes Mellitus; Dose-Response Relationship, Drug; Drug Evaluation; Drug Therapy, Combination; Follow-Up Studies; Glipizide; Humans; Middle Aged; Phenformin; Sulfonylurea Compounds; Tolbutamide | 1976 |
[Therapeutic effect of glibenclamide contrasted with other oral antidiabetic agents].
Topics: Administration, Oral; Adult; Biguanides; Chlorpropamide; Chronic Disease; Clinical Trials as Topic; Diabetes Mellitus; Drug Evaluation; Drug Therapy, Combination; Female; Glyburide; Humans; Hypoglycemic Agents; Male; Middle Aged; Tolbutamide | 1975 |
Effect of magnesium hydroxide on the absorption and efficacy of tolbutamide and chlorpropamide.
Topics: Adult; Blood Glucose; Chlorpropamide; Drug Interactions; Female; Humans; Insulin; Intestinal Absorption; Magnesium Hydroxide; Male; Tolbutamide | 1992 |
Efficacy of gliclazide in comparison with other sulphonylureas in the treatment of NIDDM.
Topics: Blood Glucose; Chlorpropamide; Diabetes Mellitus, Type 2; Diet, Diabetic; Gliclazide; Glipizide; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Tolbutamide | 1991 |
[Clinical evaluation of a new sulfonylurea derivative, preparation SPC-703, based on a 5-year observation].
Topics: Chlorpropamide; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Sulfonylurea Compounds; Time Factors; Tolbutamide | 1985 |
Effect of diet, sulphonylureas, and phenformin on peripheral glucose uptake in diabetes and obesity.
Topics: Adult; Aged; Blood Flow Velocity; Body Weight; Chlorpropamide; Diabetes Mellitus; Diet Therapy; Female; Glucose; Glucose Tolerance Test; Humans; Male; Middle Aged; Obesity; Phenformin; Tolbutamide | 1968 |
Preliminary trial of a powerful new sulphonylurea in maturity-onset diabetes--HB419 (glibenclamide).
Topics: Adult; Age Factors; Aged; Blood Chemical Analysis; Chlorpropamide; Clinical Trials as Topic; Diabetes Mellitus; Female; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Phenformin; Sulfonamides; Tolbutamide | 1969 |
Clinical trial of a new sulphonylurea in maturity-onset diabetes--HB419 (glibenclamide).
Topics: Age Factors; Chlorpropamide; Clinical Trials as Topic; Diabetes Mellitus; Female; Humans; Hypoglycemic Agents; Male; Racial Groups; Sex Factors; Tolbutamide | 1969 |
HB419 (glibenclamide) in the treatment of diabetes mellitus.
Topics: Adult; Age Factors; Aged; Biguanides; Chlorpropamide; Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitus; Female; Gallbladder Diseases; Gastrointestinal Diseases; Humans; Hypoglycemic Agents; Kidney Diseases; Liver Diseases; Male; Metformin; Middle Aged; Phenformin; Sulfonamides; Tolbutamide; Urea; Vascular Diseases | 1969 |
[Clinical testing of a sulfonylurea preparation (glibenclamide)].
Topics: Adult; Aged; Chlorpropamide; Clinical Trials as Topic; Diabetes Mellitus; Diet Therapy; Female; Glyburide; Humans; Hypoglycemic Agents; Male; Middle Aged; Tolbutamide | 1969 |
Sulphonylurea therapy in the treatment of the pregnant diabetic.
Topics: Abnormalities, Drug-Induced; Adult; Apgar Score; Blood Glucose; Chlorpropamide; Diet Therapy; Female; Fetal Death; Humans; Infant Mortality; Infant, Newborn; Infant, Newborn, Diseases; Insulin; Obstetric Labor Complications; Parity; Pregnancy; Pregnancy in Diabetics; South Africa; Sulfonylurea Compounds; Tolbutamide | 1971 |
The clinical use of chlorpropamide in diabetes insipidus.
Topics: Adult; Blood Glucose; Chlorpropamide; Creatinine; Diabetes Insipidus; Diet; Diet, Sodium-Restricted; Diuresis; Diuretics; Drug Synergism; Ethanol; Female; Glomerular Filtration Rate; Humans; Male; Middle Aged; Osmolar Concentration; Placebos; Tannins; Tolbutamide; Vasopressins | 1971 |
Blood sugar lowering effects of chlorpropamide and tolbutamide. A double blind cooperative study.
Topics: Chlorpropamide; Clinical Trials as Topic; Diabetes Mellitus; Glucose Tolerance Test; Humans; Tolbutamide | 1965 |
Comparative effects of acute intravenous loads of tolbutamide, acetohexamide and chlorpropamide in normal and diabetic subjects.
Topics: Acetohexamide; Adult; Blood Glucose; Chlorpropamide; Clinical Trials as Topic; Diabetes Mellitus; Female; Humans; Male; Middle Aged; Tolbutamide | 1965 |
A clinical pharmacologic comparison of glyhexamide, tolbutamide and chlorpropamide in the treatment of stable diabetes.
Topics: Adult; Aged; Chlorpropamide; Clinical Trials as Topic; Diabetes Mellitus; Female; Humans; Male; Middle Aged; Sulfonylurea Compounds; Tolbutamide | 1967 |
Long-term experience with sulfonylureas and placebo.
Topics: Blood Glucose; Blood Urea Nitrogen; Chlorpropamide; Clinical Trials as Topic; Diabetes Mellitus; Follow-Up Studies; Humans; Hypoglycemic Agents; Placebos; Psychosomatic Medicine; Tolbutamide | 1967 |
Circadian variation of glucose, insulin, and free fatty acids during long-term use of oral hypoglycaemic agents in diabetes mellitus.
Topics: Aged; Blood Glucose; Chlorpropamide; Circadian Rhythm; Diabetes Mellitus; Diet, Diabetic; Fatty Acids, Nonesterified; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Metformin; Middle Aged; Obesity; Starvation; Tolbutamide | 1968 |
Restraint in use of oral antidiabetic drugs.
Topics: Blood Glucose; Chlorpropamide; Humans; Hypoglycemic Agents; Placebos; Tolbutamide | 1967 |
Influence of food and age on the single-dose kinetics and effects of tolbutamide and chlorpropamide.
Topics: Administration, Oral; Adult; Aged; Blood Glucose; Chlorpropamide; Clinical Trials as Topic; Fasting; Female; Food; Half-Life; Humans; Insulin; Kinetics; Male; Tolbutamide | 1980 |
331 other study(ies) available for chlorpropamide and tolbutamide
| Article | Year |
|---|---|
Inhibitory effect of novel oral hypoglycemic agent nateglinide (AY4166) on peptide transporters PEPT1 and PEPT2.
Topics: Administration, Oral; Alanine; Animals; Caco-2 Cells; Carrier Proteins; Cyclohexanes; Dipeptides; Humans; Hypoglycemic Agents; Kinetics; Nateglinide; Peptide Transporter 1; Phenylalanine; Rats; Symporters; Threonine | 2000 |
Inhibitory effect of anti-diabetic agents on rat organic anion transporter rOAT1.
Topics: Animals; Anion Transport Proteins; Binding, Competitive; Carbon Radioisotopes; Carrier Proteins; Chlorpropamide; Cyclohexanes; Dose-Response Relationship, Drug; Female; Glyburide; Hypoglycemic Agents; Kinetics; Nateglinide; Oocytes; p-Aminohippuric Acid; Phenylalanine; Rats; RNA, Complementary; Sulfonylurea Compounds; Tolbutamide; Xenopus | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chemical Phenomena; Chemistry, Physical; Humans; In Vitro Techniques; Interleukin-8; Models, Molecular; Phenylpropionates; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin; Stereoisomerism | 2005 |
Three-dimensional quantitative structure-activity relationship analysis of human CYP51 inhibitors.
Topics: Amides; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Humans; Indoles; Models, Molecular; Oxidoreductases; Quantitative Structure-Activity Relationship; Sterol 14-Demethylase | 2007 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions.
Topics: Binding Sites; Crystallography, X-Ray; Drug Interactions; Humans; Pharmaceutical Preparations; Protein Binding; Protein Structure, Tertiary; Serum Albumin; Spectrometry, Fluorescence | 2010 |
Elucidation of common pharmacophores from analysis of targeted metabolites transported by the multispecific drug transporter-Organic anion transporter1 (Oat1).
Topics: Animals; Cluster Analysis; Computer Simulation; Databases, Factual; Drug Design; Mice; Mice, Knockout; Organic Anion Transport Protein 1; Pharmaceutical Preparations; ROC Curve | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Drug concentration in saliva.
Topics: Adolescent; Adult; Aged; Antipyrine; Chlorpropamide; Humans; Hydrogen-Ion Concentration; Male; Meperidine; Middle Aged; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Propranolol; Protein Binding; Saliva; Tolbutamide | 1978 |
High-performance liquid chromatographic determination of glipizide and some other sulfonylurea drugs in serum.
Topics: Chlorpropamide; Chromatography, High Pressure Liquid; Glipizide; Glyburide; Humans; Hydrogen-Ion Concentration; Sulfonylurea Compounds; Tolbutamide | 1979 |
Effect of inhibitors of sterol biosynthesis on growth and sexuality of Pythium and Zygorhynchus.
Topics: Chlorpropamide; Fungi; Maleates; Mucorales; Proadifen; Pythium; Tolbutamide; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride | 1976 |
Hyaluronidase-induced inhibition of the insulinotropic action of sulfonylureas, leucine, and glucagon in rodent isolated pancreatic islets.
Topics: Animals; Chlorpropamide; Cricetinae; Female; Glucagon; Glucose; Glyburide; Hyaluronoglucosaminidase; Insulin; Islets of Langerhans; Leucine; Mice; Microbial Collagenase; Rats; Species Specificity; Sulfonylurea Compounds; Tolbutamide | 1976 |
Inhibition of vasopressin-stimulated prostaglandin E biosynthesis by chlorpropamide in the toad urinary bladder. Mechanism of enhancement of vasopressin-stimulated water flow.
Topics: Animals; Anura; Arginine Vasopressin; Chlorpropamide; Chromatography, Thin Layer; Cyclic AMP; Glyburide; Lipid Metabolism; Permeability; Prostaglandins E; Stimulation, Chemical; Structure-Activity Relationship; Theophylline; Tolbutamide; Urinary Bladder; Vasopressins; Water | 1977 |
The effects of sulfonylureas on peripheral metabolic processes.
Topics: Animals; Chlorpropamide; Cyclic AMP; Diuresis; Glucose; Humans; Hypothyroidism; Metabolism; Mice; Myocardial Contraction; Phosphoric Diester Hydrolases; Platelet Aggregation; Rabbits; Sulfonylurea Compounds; Tolbutamide; Water-Electrolyte Balance | 1977 |
Modification of diuresis in the rat by chlorpropamide, glibenclamide and tolbutamide.
Topics: Administration, Oral; Animals; Body Water; Chlorpropamide; Diabetes Mellitus; Diuresis; Glyburide; Hydrogen-Ion Concentration; Male; Potassium; Rats; Sodium; Streptozocin; Time Factors; Tolbutamide | 1975 |
Side effects of therapy in diabetes evaluated by a self-administered questionnaire.
Topics: Chlorpropamide; Diabetes Mellitus; Diet, Diabetic; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Male; Metformin; Middle Aged; Patient Acceptance of Health Care; Phenformin; Surveys and Questionnaires; Tolbutamide | 1977 |
The pharmacology of a new hypoglycaemic agent N-[4-(2-(2,3-dihydrobenzo(b)furan-7-carboxamid o)-ethyl)-benzenesulphonyl]-N'-cyclohexlurea (NOVO CS 476). III. General pharmacological studies.
Topics: Animals; Blood Pressure; Cats; Chlorpropamide; Diuresis; Dogs; Female; Glyburide; Guinea Pigs; Heart; Hypoglycemic Agents; Male; Muscle Contraction; Muscle, Smooth; Papillary Muscles; Rats; Sulfonylurea Compounds; Tolbutamide | 1977 |
[Clinico-statistical studies of the use of oral hypoglycemic agents in the therapy of diabetes: critical evaluation of their effectiveness and tolerance].
Topics: Adult; Aged; Chlorpropamide; Diabetes Mellitus; Drug Evaluation; Drug Therapy, Combination; Female; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Phenformin; Tolbutamide | 1977 |
[Hypoglycemic sulfonylurea metabolites: clinical interest. Experiences with glibenclamide in the rat].
Topics: Animals; Biotransformation; Blood Glucose; Chlorpropamide; Glyburide; Injections, Intraperitoneal; Rats; Tolbutamide | 1977 |
Stability-indicating high-performance liquid chromatographic determination of chlorpropamide, tolbutamide, and their respective sulfonamide degradates.
Topics: Chlorpropamide; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Drug Stability; Methods; Sulfonamides; Tablets; Tolbutamide | 1979 |
Reduction of the severity of nephropathy in aging Fischer 344 rats treated with analogs of arylsulfonyluria.
Topics: Acetohexamide; Animals; Chlorpropamide; Female; Hypoglycemic Agents; Kidney Diseases; Male; Phenformin; Rats; Rats, Inbred F344; Sulfonylurea Compounds; Tolazamide; Tolbutamide | 1979 |
[Biopharmaceutical studies on pyridinolcarbamate. IV. Effect of continuous pyridinolcarbamate administration on hypoglycemic activity of tolbutamide and chlorpropamide in rabbits (author's transl)].
Topics: Animals; Carbamates; Chlorpropamide; Drug Synergism; Hypoglycemic Agents; Male; Pyridinolcarbamate; Rabbits; Tolbutamide | 1979 |
Serum tolbutamide and chlorpropamide concentrations in patients with diabetes mellitus.
Topics: Adult; Aged; Blood Glucose; Chlorpropamide; Chromatography, Gas; Diabetes Mellitus; Humans; Middle Aged; Tolbutamide | 1978 |
Determination of serum tolbutamide and chlorpropamide by high-performance liquid chromatography.
Topics: Chlorpropamide; Chromatography, High Pressure Liquid; Humans; Methods; Tolbutamide | 1978 |
Drug compliance in diabetics.
Topics: Chlorpropamide; Diabetes Mellitus; Humans; Patient Compliance; Tolbutamide | 1978 |
[Group sensitization by photosensitizing drugs].
Topics: Carbutamide; Chlorpropamide; Drug Interactions; Photosensitivity Disorders; Promethazine; Structure-Activity Relationship; Sulfamethoxazole; Sulfonamides; Tartrazine; Tolbutamide | 1978 |
[Specific protection by sulfhydryl groups against inhibition of urease by hypoglycaemic drugs (author's transl)].
Topics: Chlorpropamide; Cysteine; Drug Interactions; Enzyme Activation; Glutathione; Humans; Hydroxymercuribenzoates; Tolbutamide; Urease | 1978 |
Effect of control of blood glucose on plasma insulin responses to various stimuli in secondary failures to oral hypoglycemic agents and in newly diagnosed, maturity onset, ketosis-resistant diabetics.
Topics: Adult; Aged; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Female; Glucose Tolerance Test; Humans; Insulin; Male; Middle Aged; Tolazamide; Tolbutamide | 1978 |
Myocardial infarction in diabetics.
Topics: Administration, Oral; Adult; Aged; Chlorpropamide; Coronary Care Units; Diabetes Complications; Diabetes Mellitus; Diabetic Retinopathy; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Male; Metformin; Middle Aged; Myocardial Infarction; Phenformin; Sex Factors; Sulfonylurea Compounds; Tolbutamide | 1975 |
Electron microscopic study on zinc in B cells of pancreatic islets of rat under conditions stimulating the excretion of insulin.
Topics: Animals; Chlorpropamide; Cytoplasmic Granules; Glucose; Histocytochemistry; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Protein Binding; Rats; Sulfides; Tolbutamide; Zinc | 1975 |
Circular dichroism studies on the interaction of sulfonylureas with bovine and human serum albumin.
Topics: Binding Sites; Binding, Competitive; Carbutamide; Chlorpropamide; Circular Dichroism; Glipizide; Glyburide; Humans; In Vitro Techniques; Optical Rotatory Dispersion; Protein Binding; Serum Albumin; Serum Albumin, Bovine; Sulfonylurea Compounds; Tolbutamide | 1976 |
Displacement of tolbutamide, glibencalmide and chlorpropamide from serum albumin by anionic drugs.
Topics: Acetaminophen; Animals; Cattle; Chlorpropamide; Dialysis; Glyburide; Humans; Phenylbutazone; Protein Binding; Salicylates; Serum Albumin; Serum Albumin, Bovine; Sulfaphenazole; Tolbutamide; Warfarin | 1976 |
Measurement of antidiabetic sulfonylureas in serum by gas chromatography with electron-capture detection.
Topics: Chemical Phenomena; Chemistry; Chlorpropamide; Chromatography, Gas; Diabetes Mellitus; Electrons; Humans; Mass Spectrometry; Sulfonylurea Compounds; Tolbutamide; Trifluoroacetic Acid | 1977 |
The effect of chronic oral antidiabetic therapy on insulin and glucagon responses to a meal.
Topics: Acetohexamide; Administration, Oral; Adult; Aged; Chlorpropamide; Diabetes Mellitus; Female; Glucagon; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Phenformin; Time Factors; Tolazamide; Tolbutamide | 1977 |
[Inhibition of urease by hypoglycaemic drugs (author's transl)].
Topics: Chlorpropamide; Tolbutamide; Urease | 1977 |
Assay of sulfonylureas in human plasma by high-performance liquid chromatography.
Topics: Chlorpropamide; Chromatography, High Pressure Liquid; Humans; Tolbutamide | 1976 |
Gas chromatographic and mass spectrometric analysis of the products of methylation of sulfonylurea drugs.
Topics: Chemical Phenomena; Chemistry; Chlorpropamide; Chromatography, Gas; Mass Spectrometry; Methods; Methylation; Tolbutamide | 1976 |
The management of pregnancy in diabetes mellitus.
Topics: Birth Weight; Blood Glucose; Chlorpropamide; Delivery, Obstetric; Diet, Diabetic; Female; Fetal Death; Humans; Infant, Newborn; Insulin; Ketosis; Maternal Age; Metformin; Phenformin; Pregnancy; Pregnancy in Diabetics; Time Factors; Tolbutamide | 1975 |
Influence of diabetes mellitus on drug metabolism in man.
Topics: Antipyrine; Chlorpropamide; Diabetes Mellitus; Diet, Diabetic; Female; Half-Life; Humans; Insulin; Kinetics; Male; Middle Aged; Pharmaceutical Preparations; Tolbutamide | 1976 |
GLC determination of plasma levels of intact chlorpropamide or tolbutamide.
Topics: Biological Availability; Chlorpropamide; Chromatography, Gas; Humans; Kinetics; Male; Methods; Methylation; Tolbutamide | 1976 |
A screening test for detecting sulfonylureas in plasma.
Topics: Aged; Aged, 80 and over; Chlorpropamide; Chromatography, High Pressure Liquid; Female; Gliclazide; Glipizide; Glyburide; Humans; Hypoglycemia; Male; Middle Aged; Sulfonylurea Compounds; Tolbutamide | 1990 |
An infrared study of tautomerism in acetohexamide polymorphs.
Topics: Acetohexamide; Chlorpropamide; Crystallization; Spectrophotometry, Infrared; Stereoisomerism; Tolbutamide; X-Ray Diffraction | 1989 |
Effect of glipizide on hepatic fructose 2,6-bisphosphate concentration and glucose metabolism.
Topics: Animals; Chlorpropamide; Cyclic AMP; Fructosediphosphates; Glipizide; Gluconeogenesis; Glucose; Hexosediphosphates; Hexosephosphates; In Vitro Techniques; Lactates; Liver; Male; Rats; Rats, Inbred Strains; Sulfonylurea Compounds; Tolbutamide | 1987 |
Determination of glibenclamide, chlorpropamide and tolbutamide in plasma by high-performance liquid chromatography with ultraviolet detection.
Topics: Chlorpropamide; Chromatography, High Pressure Liquid; Diabetes Mellitus; Dinitrofluorobenzene; Gas Chromatography-Mass Spectrometry; Glyburide; Humans; Spectrophotometry, Ultraviolet; Tolbutamide | 1985 |
Sulfonylurea stimulates liver fructose-2,6-bisphosphate formation in proportion to its hypoglycemic action.
Topics: Acetohexamide; Animals; Buformin; Chlorpropamide; Fructosediphosphates; Gliclazide; Gluconeogenesis; Glyburide; Glycolysis; Hexosediphosphates; In Vitro Techniques; Liver; Male; Rats; Rats, Inbred Strains; Stimulation, Chemical; Sulfamethoxazole; Sulfonylurea Compounds; Tolbutamide | 1985 |
Effect of tolbutamide and chlorpropamide on acetaldehyde metabolism in two inbred strains of mice.
Topics: Acetaldehyde; Administration, Oral; Aldehyde Dehydrogenase; Animals; Chlorpropamide; Drug Interactions; Ethanol; Genotype; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mitochondria, Liver; Species Specificity; Tolbutamide | 1985 |
Plasma-insulin in a young diabetic after 13 years' oral therapy.
Topics: Administration, Oral; Adolescent; Child; Chlorpropamide; Diabetes Mellitus, Type 1; Humans; Insulin; Male; Time Factors; Tolbutamide | 1971 |
Displacement of sulfonylureas from human serum proteins by coumarin derivatives and cortical steroids.
Topics: Acetohexamide; Adrenal Cortex Hormones; Alpha-Globulins; Chlorpropamide; Coumarins; Dose-Response Relationship, Drug; Humans; Hydrogen-Ion Concentration; Phenindione; Protein Binding; Serum Albumin; Sulfonylurea Compounds; Tolbutamide | 1973 |
Antidiuretic action of chlorpropamide.
Topics: Chlorpropamide; Diuresis; Female; Glyburide; Humans; Male; Tolbutamide | 1973 |
Effect of short and long term chlorpropamide treatment of insulin release and blood-glucose.
Topics: Administration, Oral; Adult; Aged; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Glucagon; Glucose; Glucose Tolerance Test; Humans; Injections, Intravenous; Insulin; Insulin Secretion; Islets of Langerhans; Middle Aged; Time Factors; Tolbutamide | 1974 |
Letter: Oral hypoglycaemic therapy in diabetic pregnancies.
Topics: Administration, Oral; Antigens; Biguanides; Blood Glucose; Chlorpropamide; Female; Humans; Insulin; Insulin Secretion; Pregnancy; Pregnancy in Diabetics; Pregnancy Trimester, Third; Tolbutamide | 1974 |
Determination of tolbutamide and chlorpropamide in biological fluids.
Topics: Chlorpropamide; Chromatography, Gas; Colorimetry; Tolbutamide | 1973 |
The binding of sulphonylureas to serum albumin.
Topics: Animals; Carbon Radioisotopes; Cattle; Chlorpropamide; Glyburide; Humans; Hydrogen-Ion Concentration; Protein Binding; Serum Albumin; Serum Albumin, Bovine; Sulfonylurea Compounds; Tolazamide; Tolbutamide | 1974 |
[Drug induced changes of the blood glucose lowering effect of oral hypoglycemic agents].
Topics: Aged; Blood Glucose; Chlorpropamide; Chromatography, Thin Layer; Dicumarol; Drug Synergism; Humans; Hypoglycemia; Hypoglycemic Agents; Liver; Protein Binding; Sulfaphenazole; Sulfur Isotopes; Tolbutamide | 1969 |
Chlorpropamide and chloramphenicol.
Topics: Chloramphenicol; Chlorpropamide; Humans; Kidney; Tolbutamide | 1970 |
Observations of the mechanism of action of the sulfonylureas under clinical conditions.
Topics: Adult; Aged; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Fasting; Female; Glyburide; Humans; Hypoglycemia; Insulin; Male; Middle Aged; Time Factors; Tolbutamide | 1973 |
The effect of glibenclamide on non-esterified fatty acid levels in the plasma of the severely alloxan diabetic rat.
Topics: Animals; Blood Glucose; Chlorpropamide; Diabetes Mellitus, Experimental; Fatty Acids, Nonesterified; Glyburide; Insulin; Male; Rats; Tolbutamide | 1973 |
[A comparison of intravenous tolbutamide and insulin administration during and after operation in patients with maturity-onset diabetes (author's transl)].
Topics: Administration, Oral; Age Factors; Aged; Anesthesia, General; Blood Glucose; Carbohydrates; Carbutamide; Chlorpropamide; Diabetes Complications; Diabetes Mellitus; Diet Therapy; Fructose; Glyburide; Glycosuria; Humans; Injections, Intravenous; Insulin; Ketone Bodies; Plasma Substitutes; Postoperative Care; Preoperative Care; Surgical Procedures, Operative; Tolbutamide | 1974 |
[Hypoglycemia caused by oral antidiabetic agents].
Topics: Adult; Aged; Chlorpropamide; Delayed-Action Preparations; Diet; Female; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Kidney Diseases; Liver Diseases; Male; Middle Aged; Phenformin; Tolazamide; Tolbutamide | 1973 |
Homeostasis of body weight in a diabetes clinic population.
Topics: Acetohexamide; Adolescent; Adult; Age Factors; Aged; Appetite Regulation; Blood Glucose; Body Weight; Child; Chlorpropamide; Diabetes Mellitus; Diabetic Ketoacidosis; Diet Therapy; Feeding Behavior; Female; Homeostasis; Humans; Insulin; Male; Middle Aged; Phenformin; Regression Analysis; Time Factors; Tolbutamide | 1974 |
Interactions of sulfonylureas with plasma proteins.
Topics: Acetohexamide; Acridines; Aniline Compounds; Animals; Binding Sites; Blood Proteins; Cattle; Chlorpropamide; Cyclohexanes; Glyburide; Humans; Hypoglycemic Agents; Naphthalenesulfonates; Protein Binding; Pyrazines; Serum Albumin; Serum Albumin, Bovine; Spectrometry, Fluorescence; Sulfonylurea Compounds; Tolbutamide; Warfarin | 1974 |
Editorial: Oral therapy in diabetes mellitus.
Topics: Acetohexamide; Biguanides; Chlorpropamide; Diabetes Mellitus; Diabetic Ketoacidosis; Diet Therapy; Humans; Hypoglycemia; Hypoglycemic Agents; Lactates; Phenformin; Placebos; Pyruvates; Sulfonylurea Compounds; Tolazamide; Tolbutamide; Typhoid Fever | 1974 |
Clinical assessment of glybenclamide (daonil) in diabetes mellitus.
Topics: Chlorpropamide; Diabetes Mellitus; Female; Glyburide; Humans; Male; Tolbutamide | 1973 |
Effect of hypoglycemic sulfonylureas on hepatic fructose metabolism in the rat.
Topics: Acetoacetates; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Chlorpropamide; Fasting; Flavoproteins; Fructose; Gluconeogenesis; Glyburide; Hydrogen-Ion Concentration; Hydroxybutyrates; Hypoglycemia; Ketone Bodies; Liver; Male; Mitochondria, Liver; Oxidation-Reduction; Perfusion; Rats; Spectrometry, Fluorescence; Sulfonylurea Compounds; Time Factors; Tolbutamide | 1974 |
[The glibenclamide-phenformin combination in the therapy of diabetes mellitus].
Topics: Adult; Aged; Biguanides; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Drug Combinations; Drug Evaluation; Drug Synergism; Female; Glyburide; Humans; Insulin; Male; Middle Aged; Phenformin; Tolbutamide | 1974 |
Zinc and insulin content in pancreatic islets of rats after administration of hypoglycemic sulfonamides.
Topics: Animals; Blood Glucose; Chlorpropamide; Glyburide; Histocytochemistry; Hypoglycemic Agents; Insulin; Islets of Langerhans; Male; Rats; Tolbutamide; Zinc | 1974 |
Oral management of uncomplicated maturity onset diabetes.
Topics: Adult; Aged; Biguanides; Chlorpropamide; Diabetes Mellitus; Diet; Drug Combinations; Glucose Tolerance Test; Glyburide; Humans; Hypoglycemic Agents; Insulin; Middle Aged; Obesity; Sulfonylurea Compounds; Tolbutamide | 1974 |
[Effect of oral antidiabetics on the unesterified fatty acid content of rat plasma].
Topics: Adrenal Glands; Adrenalectomy; Animals; Carbutamide; Chlorpropamide; Epinephrine; Fatty Acids, Nonesterified; Hypoglycemia; Hypoglycemic Agents; Norepinephrine; Rats; Tolbutamide | 1967 |
Displacement of phenprocoumon (Marcumar) from albumin by sulfonylurea compounds, suramin, and ioglycamic acid.
Topics: Animals; Anticoagulants; Benzoates; Benzyl Compounds; Binding Sites; Carbutamide; Cattle; Chlorpropamide; Chromatography, Gel; Coumarins; Dextrans; Glycolates; In Vitro Techniques; Iodobenzoates; Protein Binding; Serum Albumin, Bovine; Sulfonylurea Compounds; Suramin; Tolbutamide | 1972 |
Metabolic effects of hypoglycemic sulfonylureas. V. In vitro effects of sulfonylureas on mitochondrial adenosine triphosphatase activity.
Topics: Acetohexamide; Adenosine Triphosphatases; Animals; Carbutamide; Chlorpropamide; Dinitrophenols; Hypoglycemic Agents; In Vitro Techniques; Male; Mitochondria, Liver; Oligomycins; Oxidative Phosphorylation; Rats; Stimulation, Chemical; Sulfonylurea Compounds; Tolbutamide | 1974 |
[Histochemical study on the endocrine function of the islets of Langerhans with special reference to changes in protein-bound disulfide and sulfhydryl groups in B cells].
Topics: Adenoma, Islet Cell; Animals; Blood Glucose; Child; Chlorpropamide; Female; Glucose; Glycogen Storage Disease Type I; Humans; Insulin; Islets of Langerhans; Male; Middle Aged; Protein Binding; Proteins; Rats; Sulfhydryl Compounds; Sulfides; Tolbutamide | 1966 |
Hypernatremia due to hypodipsia and elevated threshold for vasopressin release. Effects of treatment with hydrochlorothiazide, chlorpropamide and tolbutamide.
Topics: Chlorpropamide; Creatinine; Cyclic AMP; Dehydration; Diuresis; Female; Humans; Hydrochlorothiazide; Hypernatremia; Hypothalamus; Insulin; Insulin Secretion; Islets of Langerhans; Kidney; Middle Aged; Osmolar Concentration; Sodium; Thirst; Tolbutamide; Vasopressins; Water; Water-Electrolyte Balance | 1968 |
Chlorpropamide and tolbutamide inhibition of adenosine 3'5' cyclic monophosphate phosphodiesterase.
Topics: Animals; Arteriosclerosis; Caffeine; Chlorpropamide; Cyclic AMP; Kidney; Phosphoric Monoester Hydrolases; Rats; Tolbutamide; Tritium | 1971 |
Effect of sulfonylureas on the permeability to water and electrical properties of the urinary bladder of the toad.
Topics: Acetohexamide; Animals; Anura; Biguanides; Biological Transport; Calcium; Carbutamide; Cell Membrane Permeability; Chlorpropamide; Cyclic AMP; Depression, Chemical; Dinitrophenols; Electrophysiology; Epinephrine; Glutathione; Pyrimidines; Stimulation, Chemical; Sulfonic Acids; Temperature; Theophylline; Tolbutamide; Urinary Bladder; Vasopressins; Water | 1970 |
Mode of action of oral hypoglycaemic agents. II. Sulphonylureas & biguanides in rats.
Topics: Acetohexamide; Administration, Oral; Adrenocorticotropic Hormone; Animals; Carbohydrate Metabolism; Chlorpropamide; Depression, Chemical; Enzyme Inhibitors; Epinephrine; Glucose; Glucose-6-Phosphatase; Glucosephosphate Dehydrogenase; Hypoglycemic Agents; In Vitro Techniques; Insulin; Isomerases; Lipoprotein Lipase; Metabolism; Muscles; Phenformin; Phosphorylases; Rats; Stimulation, Chemical; Sulfonylurea Compounds; Tolbutamide; Trioses | 1969 |
Perspective. Chlorpropamide hyponatremia.
Topics: Age Factors; Aged; Chlorpropamide; Cyclic AMP; Humans; Hyponatremia; Syndrome; Tolbutamide; Vasopressins | 1972 |
The effect of sulfonylurea drugs on rabbit myocardial contractility, canine purkinje fiber automaticity, and adenyl cyclase activity from rabbit and human hearts.
Topics: Acetohexamide; Adenylyl Cyclases; Animals; Chlorpropamide; Culture Techniques; Cyclic AMP; Dogs; Heart; Heart Atria; Heart Conduction System; Humans; Membrane Potentials; Microelectrodes; Myocardium; Phenformin; Propranolol; Rabbits; Stimulation, Chemical; Sulfonylurea Compounds; Theophylline; Tolazamide; Tolbutamide | 1972 |
Clinical use of radioimmunological plasma insulin assessment.
Topics: Adenoma, Islet Cell; Adult; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Diet; Glucose Tolerance Test; Humans; Hyperglycemia; Hyperinsulinism; Insulin; Male; Middle Aged; Pancreatic Diseases; Pancreatic Neoplasms; Radioimmunoassay; Sulfonylurea Compounds; Tolbutamide | 1973 |
Inhibition of lipid biosynthesis.
Topics: Acetates; Animals; Anticholesteremic Agents; Antimetabolites; Chlorpropamide; Cholestanes; Cholesterol; Chromatography; Depression, Chemical; Hydroxysteroid Dehydrogenases; Hypolipidemic Agents; Lipids; Liver; Mevalonic Acid; NADP; Phenformin; Rats; Squalene; Sterols; Tolbutamide; Tritium | 1968 |
Gas-liquid chromatographic estimation of tolbutamide and chlorpropamide in plasma.
Topics: Alkalies; Chlorpropamide; Chromatography, Gas; Methods; Sulfates; Tolbutamide; Toluene | 1972 |
Complex formation between macromolecules and drugs. X. Binding of tolbutamide, chlorpropamide and carbutamide to human serum albumin, and the competition between tolbutamide or chlorpropamide and carbutamide or 4-sulfanilamido-2,6-dimethylpyrimidine for b
Topics: Binding Sites; Binding, Competitive; Carbutamide; Chlorpropamide; Dialysis; Humans; Hydrogen-Ion Concentration; Hypoglycemic Agents; Protein Binding; Serum Albumin; Sulfadimethoxine; Tolbutamide | 1974 |
Circadian variations of carbohydrate tolerance in maturity onset diabetics treated with sulfonylureas.
Topics: Aged; Blood Glucose; Body Weight; Camphanes; Capillaries; Chlorpropamide; Circadian Rhythm; Diabetes Mellitus; Fatty Acids, Nonesterified; Female; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insulin; Insulin Antibodies; Male; Middle Aged; Sulfonylurea Compounds; Time Factors; Tolbutamide | 1974 |
Drug-induced malabsorption of vitamin B12. VI. Malabsorption of vitamin B12 during treatment with phenformin.
Topics: Aged; Chlorpropamide; Cobalt Radioisotopes; Diabetes Mellitus; Humans; Middle Aged; Phenformin; Schilling Test; Tolbutamide; Vitamin B 12; Vitamin B 12 Deficiency; Xylose | 1974 |
An analysis of the effect of hypoalbuminemia on the amount of free drug in plasma for drugs bound at two sets of sites.
Topics: Binding Sites; Carbenoxolone; Chlorpromazine; Chlorpropamide; Computers; Dose-Response Relationship, Drug; Humans; Iopanoic Acid; Pharmaceutical Preparations; Phenylbutazone; Protein Binding; Quinidine; Salicylates; Serum Albumin; Sulfadiazine; Tolbutamide | 1974 |
[Hypoglycemic sulfamides and biguanides].
Topics: Biguanides; Chlorpropamide; Diabetes Mellitus; Sulfonylurea Compounds; Tolbutamide | 1972 |
Haemolytic anaemia associated with antibodies to tolbutamide and phenacetin.
Topics: Anemia, Hemolytic; Antibodies; Chlorpropamide; Coombs Test; Cross Reactions; Female; Glyburide; Humans; Middle Aged; Phenacetin; Tolbutamide | 1972 |
[Role of glibenclamide in the therapy of diabetes].
Topics: Adult; Chlorpropamide; Diabetes Mellitus; Evaluation Studies as Topic; Glyburide; Glycosuria; Humans; Insulin; Insulin Secretion; Sulfonylurea Compounds; Tolbutamide | 1972 |
A dose equivalence study of glybenclamide (daonil)--a new hypoglycaemic agent.
Topics: Adult; Chlorpropamide; Diabetes Mellitus; Female; Glyburide; Humans; Male; Sulfonylurea Compounds; Therapeutic Equivalency; Tolbutamide | 1972 |
Oral therapy in diabetes.
Topics: Acetohexamide; Administration, Oral; Animals; Chlorpropamide; Diabetes Mellitus; Diet Therapy; Evaluation Studies as Topic; Glyburide; Humans; Hypoglycemic Agents; Insulin; Metformin; Obesity; Phenformin; Pyrimidines; Sulfonamides; Time Factors; Tolbutamide | 1972 |
Diabetes mellitus: the thin maturity-onset diabetic.
Topics: Acetohexamide; Body Weight; Chlorpropamide; Diabetes Mellitus; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Male; Middle Aged; Tolazamide; Tolbutamide | 1972 |
Effects of tolbutamide and of chlorpropamide on fatty acid synthesis.
Topics: Acetates; Adenosine Triphosphate; Animals; Carbon Isotopes; Chlorpropamide; Epididymis; Fasting; Fatty Acids; Glucose; Liver; Male; Perfusion; Rats; Tolbutamide; Tritium | 1972 |
Treatment of chemical diabetes mellitus with sulfonylurea compounds.
Topics: Adolescent; Adult; Child; Chlorpropamide; Diabetes Mellitus; Evaluation Studies as Topic; Humans; Insulin; Sulfonylurea Compounds; Tolbutamide | 1973 |
Long-term results with oral hypoglycemic drugs.
Topics: Acetohexamide; Adult; Aged; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Diet, Diabetic; Humans; Longevity; Middle Aged; Phenformin; Sulfonylurea Compounds; Tolazamide; Tolbutamide | 1973 |
Binding of sulfonylureas to serum albumin.
Topics: Animals; Binding, Competitive; Buffers; Cattle; Chlorpropamide; Dialysis; Humans; Protein Binding; Regression Analysis; Serum Albumin; Serum Albumin, Bovine; Spectrophotometry, Ultraviolet; Sulfonylurea Compounds; Tolbutamide | 1973 |
Effect of sulphonylureas (tolazamide, tolbutamide and chlorpropamide) on the metabolism of diphenylhydantoin in the rat.
Topics: Animals; Brain; Carbon Radioisotopes; Chlorpropamide; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Half-Life; Hydroxylation; In Vitro Techniques; Liver; Male; Phenytoin; Rats; Time Factors; Tolazamide; Tolbutamide | 1973 |
Determination of sulfonylureas and metabolites by pyrolysis gas chromatography.
Topics: Amobarbital; Chlorobenzenes; Chlorpropamide; Chromatography, Gas; Evaluation Studies as Topic; Humans; Mass Spectrometry; Methods; Pentobarbital; Phenobarbital; Secobarbital; Structure-Activity Relationship; Sulfonamides; Sulfonylurea Compounds; Time Factors; Tolazamide; Tolbutamide | 1974 |
[Glibornurid in treatment of diabetes mellitus].
Topics: Adult; Aged; Camphanes; Chlorpropamide; Diabetes Mellitus; Female; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Sulfonylurea Compounds; Tolbutamide | 1974 |
[Letter: Posthypoglycemic hyperglycemia].
Topics: Carbutamide; Chlorpropamide; Diabetes Mellitus; Humans; Hyperglycemia; Hypoglycemia; Insulin; Tolbutamide | 1974 |
[Acute suicidal poisoning with oral hypoglycemic agents (Artosin and Chloronase) in a 12-year-old boy].
Topics: Acute Disease; Child; Chlorpropamide; Glucagon; Humans; Injections, Intravenous; Injections, Subcutaneous; Male; Poisoning; Suicide; Tolbutamide | 1974 |
Fatal vascular complications in diabetic patients treated by diet, sulfonylureas and insulin. A retrospective study.
Topics: Adult; Age Factors; Aged; Cardiovascular Diseases; Cerebrovascular Disorders; Chlorpropamide; Diabetes Mellitus; Diet, Diabetic; Female; Heart Failure; Humans; Insulin; Israel; Male; Middle Aged; Myocardial Infarction; Retrospective Studies; Time Factors; Tolbutamide; Vascular Diseases | 1974 |
Establishment and in vitro endocrine function of neonatal pancreatic homografts in nondiabetic golden hamsters.
Topics: Animals; Animals, Newborn; Blood Glucose; Cheek; Chlorpropamide; Cortisone; Cricetinae; Female; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Pancreas; Pancreas Transplantation; Tolbutamide; Transplantation, Homologous | 1968 |
[Insulin liberation from the pancreas by sulfonylurea].
Topics: Animals; Blood Glucose; Chlorpropamide; Depression, Chemical; Female; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Pancreas; Rats; Tolbutamide; Urea | 1969 |
[Light-optic morphological studies on the B-cells of the islets of langerhans after administration of HB 419].
Topics: Animals; Chlorpropamide; Female; Histocytochemistry; Hypoglycemic Agents; Islets of Langerhans; Male; Pancreas; Rats; Tolbutamide; Urea; Zinc | 1969 |
[What is reliable in the therapy of diabetes mellitus?].
Topics: Carbutamide; Chlorpropamide; Chronic Disease; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Diet, Diabetic; Growth Hormone; Humans; Hyperlipidemias; Hypoglycemic Agents; Insulin; Pyrimidines; Sulfonic Acids; Thioctic Acid; Tolbutamide | 1970 |
Effect of sulfonylurea drugs on the binding of triiodothyronine and thyroxine to thyroxine-binding globulin.
Topics: Blood Protein Electrophoresis; Chlorpropamide; Humans; Iodine Radioisotopes; Ion Exchange Resins; Protein Binding; Serum Globulins; Thyroid Function Tests; Thyroxine; Thyroxine-Binding Proteins; Tolbutamide; Triiodothyronine | 1968 |
Antidiuretic effect of sulfonylureas in idiopathic diabetes insipidus.
Topics: Adult; Child; Chlorpropamide; Diabetes Insipidus; Female; Humans; Long-Term Care; Male; Osmolar Concentration; Tolbutamide; Vasopressins | 1969 |
[ADH-like mechanism of action of chlorpropamide in diabetes insipidus (a comparison with the antidiuretic effect of other blood glucose decreasing sulfonamides and hydrochlorothiazide)].
Topics: Aged; Blood Glucose; Body Weight; Chlorpropamide; Depression, Chemical; Diabetes Insipidus; Diuresis; Female; Glyburide; Humans; Hydrochlorothiazide; Hypoglycemic Agents; Male; Middle Aged; Natriuresis; Osmolar Concentration; Potassium; Sulfonylurea Compounds; Tolbutamide; Vasopressins | 1970 |
[Synergism between oral diabetics and insulin].
Topics: Animals; Biguanides; Blood Glucose; Chlorpropamide; Columbidae; Drug Synergism; Glyburide; Hypoglycemia; Hypoglycemic Agents; Insulin; Tolbutamide | 1971 |
Glibenclamide therapy in diabetes mellitus.
Topics: Adult; Aged; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Female; Humans; Hypoglycemic Agents; Long-Term Care; Male; Middle Aged; Tolbutamide | 1970 |
Studies on carbohydrate metabolism in penguins (Pygocellis papua).
Topics: Animals; Antarctic Regions; Birds; Chlorpropamide; Cold Climate; Female; Food Deprivation; Glucose; Glucose Tolerance Test; Insulin; Insulin Secretion; Male; Tolbutamide | 1972 |
Assessment of the need for continued oral therapy in diabetics.
Topics: Administration, Oral; Adult; Aged; Blood Glucose; Body Weight; Chlorpropamide; Diabetes Mellitus; Female; Humans; Hypoglycemic Agents; Male; Middle Aged; Obesity; Phenformin; Placebos; Recurrence; Sulfonylurea Compounds; Tolbutamide | 1972 |
Failure of sulfonylureas to suppress plasma glucagon in man.
Topics: Administration, Oral; Adult; Amino Acids; Blood Glucose; Chlorpropamide; Female; Glucagon; Humans; Hypoglycemia; Injections, Intravenous; Insulin; Male; Radioimmunoassay; Sulfonylurea Compounds; Tolbutamide | 1972 |
Estimation of phenytoin in body fluids in the presence of sulphonyl urea compounds.
Topics: Animals; Benzophenones; Body Fluids; Brain Chemistry; Chlorpropamide; Methods; Phenytoin; Potassium Permanganate; Rats; Spectrophotometry; Sulfonylurea Compounds; Tolazamide; Tolbutamide | 1972 |
The use of diazoxide inhibition of insulin secretion as a tool to investigate insulin stimulation by other agents.
Topics: Animals; Antigens; Chlorpropamide; Depression, Chemical; Diazoxide; Drug Antagonism; Immunoassay; Insulin; Insulin Secretion; Kinetics; Male; Mice; Mice, Inbred Strains; Stimulation, Chemical; Tolbutamide | 1972 |
Hypoglycaemia due to erroneous drug ingestion.
Topics: Adult; Chlorpropamide; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Male; Medication Errors; Phenylbutazone; Tolbutamide | 1972 |
The direct effect of oral hypoglycaemic agents on glucose metabolism by adipose tissue.
Topics: Adipose Tissue; Animals; Biological Transport; Carbon Dioxide; Carbon Isotopes; Chlorpropamide; Depression, Chemical; Epididymis; Glucose; In Vitro Techniques; Insulin; Lipids; Male; Phenformin; Rats; Stimulation, Chemical; Tolbutamide | 1972 |
Binding of sulfonylureas to serum proteins.
Topics: Acetohexamide; Carbon Isotopes; Chlorpropamide; Dialysis; Fibrinogen; Humans; Hydrogen-Ion Concentration; Lipoproteins; Protein Binding; Serum Albumin; Serum Globulins; Sulfonylurea Compounds; Sulfur Isotopes; Tolbutamide | 1972 |
[Clinical evaluation of a new sulfonylurea (Ro-6-4563) in the treatment of stable diabetes in adults].
Topics: Camphanes; Chlorpropamide; Diabetes Mellitus; Evaluation Studies as Topic; Humans; Hypoglycemic Agents; Sulfonylurea Compounds; Tolbutamide | 1972 |
Adverse reactions to oral antidiabetic agents.
Topics: Acetohexamide; Acidosis; Administration, Oral; Anemia; Chlorpropamide; Drug Antagonism; Drug Synergism; England; Ethanol; Female; Fetus; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Metformin; Phenformin; Pregnancy; Scotland; Skin Diseases; Skin Manifestations; Tolazamide; Tolbutamide; Wales | 1971 |
[Comparative activity of some biguanides, sulfonylureas and their combinations on blood sugar and lactic acid in the guinea pig. II].
Topics: Amantadine; Animals; Biguanides; Blood Glucose; Chlorpropamide; Guinea Pigs; Lactates; Metformin; Phenformin; Sulfonylurea Compounds; Tolbutamide | 1971 |
A study of comparative effectiveness of oral hypoglycaemic agents in single dose in diabetes mellitus.
Topics: Administration, Oral; Adult; Aged; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Female; Glucose Tolerance Test; Glycosuria; Humans; Male; Middle Aged; Phenformin; Time Factors; Tolbutamide | 1971 |
[88 severe incidents of hypoglycemia in patients under treatment with sulfonylurea compounds. Results of a survey throughout Switzerland during 1968 and 1969].
Topics: Age Factors; Cerebrovascular Disorders; Chlorpropamide; Diabetes Mellitus; Diagnosis, Differential; Drug Synergism; Humans; Hypoglycemia; Kidney Failure, Chronic; Retrospective Studies; Sulfonylurea Compounds; Switzerland; Tolbutamide | 1971 |
[Antidiuretic action of chlorpropamide in diabetes insipidus].
Topics: Adolescent; Adult; Aged; Biguanides; Chlorpropamide; Diabetes Insipidus; Female; Humans; Hydrochlorothiazide; Male; Tolbutamide | 1971 |
Seminars on diabetes. II. Principles of management.
Topics: Acetohexamide; Chlorpropamide; Diabetes Mellitus; Diet, Diabetic; Female; Health Education; Humans; Insulin; Male; Patient Care Team; Personality; Phenformin; Pregnancy; Pregnancy in Diabetics; Tolbutamide | 1971 |
Fibrinolytic effect of biguanides.
Topics: Adult; Aged; Angina Pectoris; Arteriosclerosis Obliterans; Biguanides; Chlorpropamide; Coronary Disease; Ethylestrenol; Female; Fibrinolysis; Fibrinolytic Agents; Humans; Male; Metformin; Methenolone; Middle Aged; Phenformin; Tolbutamide | 1968 |
[Action of tolbutamide, chlorpropamide and insulin on hyperglycemia induced by non-thiazide diuretics in rats].
Topics: Animals; Chlorpropamide; Chlorthalidone; Diuretics; Ethacrynic Acid; Female; Furosemide; Hyperglycemia; Insulin; Rats; Tolbutamide; Triamterene | 1969 |
[Diabetes mellitus therapy by sulfonylurea drugs].
Topics: Chlorpropamide; Diabetes Mellitus; Humans; Tolbutamide | 1969 |
The effect of cyclamate on the hypoglycaemic response of tolbutamide and chlorpropamide in rats.
Topics: Animals; Blood Glucose; Blood Proteins; Chlorpropamide; Cyclamates; Cyclohexanes; Drug Synergism; Hypoglycemia; Male; Protein Binding; Rats; Sweetening Agents; Tolbutamide | 1969 |
[Treatment of diabetes insipidus with chlorpropamide].
Topics: Acetohexamide; Adult; Chlorpropamide; Diabetes Insipidus; Female; Humans; Male; Tolbutamide | 1969 |
[Pharmacology of HB 419, a new strongly effective oral antidiabetic].
Topics: Adrenalectomy; Animals; Blood Glucose; Carbutamide; Chlorpropamide; Depression, Chemical; Diabetes Mellitus, Experimental; Dogs; Female; Guinea Pigs; Humans; Hypoglycemic Agents; Injections, Intravenous; Insulin; Male; Mice; Pancreatectomy; Rabbits; Rats; Time Factors; Tolbutamide; Urea | 1969 |
The magic of a name.
Topics: Chlorpropamide; Diabetes Insipidus; Humans; Terminology as Topic; Tolbutamide | 1969 |
[Clinical studies of insulin secretion by indirect methods (value of the intravenous chlorpropamide test)].
Topics: Adolescent; Chlorpropamide; Diabetes Mellitus; Humans; Insulin; Insulin Secretion; Tolbutamide | 1969 |
[Chlorpropamide and other oral hypoglycemic agents in the treatment of diabetes mellitus resistant to tolbutamide. Clinico-statistical study].
Topics: Aged; Chlorpropamide; Diabetes Mellitus; Drug Resistance; Female; Humans; Male; Middle Aged; Tolbutamide | 1969 |
Gas chromatographic method for determination of tolbutamide and chlorpropamide.
Topics: Chlorpropamide; Chromatography, Gas; Chromatography, Thin Layer; Infrared Rays; Methods; Spectrophotometry; Time Factors; Tolbutamide | 1970 |
[Chlorpropamide, tolbutamide and saluretics in the treatment of diabetes insipidus sensitive to vasopressin].
Topics: Adult; Child; Chlorpropamide; Diabetes Insipidus; Diuresis; Female; Humans; Hydrochlorothiazide; Male; Tolbutamide; Vasopressins | 1970 |
Attempts to delay the progression of chemical diabetes.
Topics: Acetohexamide; Adolescent; Adult; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Fatty Acids, Nonesterified; Female; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Phenformin; Tolbutamide; Triglycerides | 1970 |
[Hypoglycemic attacks caused by oral hypoglycemic drugs].
Topics: Aged; Biguanides; Chlorpropamide; Diabetes Mellitus; Diabetic Coma; Female; Humans; Hypoglycemia; Hypoglycemic Agents; Male; Middle Aged; Tolbutamide | 1970 |
Status of problem of usage of tolbutamide. Preliminary statements.
Topics: Acetohexamide; Chlorpropamide; Diabetes Mellitus; Diet Therapy; Humans; Tolazamide; Tolbutamide; United States; United States Food and Drug Administration | 1970 |
Hyponatremia due to sulfonylurea compounds.
Topics: Aged; Atrophy; Blood; Brain Diseases; Chlorpropamide; Diabetes Complications; Diabetes Mellitus; Female; Fludrocortisone; Humans; Hyperpituitarism; Hyponatremia; Natriuresis; Osmolar Concentration; Tolbutamide; Urine; Vasopressins | 1970 |
A comparative study on the effects of three oral hypoglycemic agents on amino acid decarboxylation.
Topics: Amino Acids; Animals; Carbon Dioxide; Carbon Isotopes; Cats; Chlorpropamide; Culture Techniques; Dogs; Hypoglycemic Agents; Liver; Phenformin; Rabbits; Tolbutamide | 1970 |
[Diuretic and natriuric action of chlorpropamide in rats with water overload. Comparison with tolbutamide].
Topics: Animals; Chlorpropamide; Diabetes Insipidus; Diuresis; Natriuresis; Rats; Tolbutamide | 1970 |
[Changes of pharmacokinetics of oral antidiabetics from drug interference and renal insufficiency].
Topics: Acetohexamide; Carbutamide; Chlorpropamide; Drug Incompatibility; Humans; Hypoglycemia; Hypoglycemic Agents; Kidney Failure, Chronic; Pyrimidines; Sulfonic Acids; Tolbutamide | 1970 |
[Oral therapy of diabetes mellitus with sulfonylurea derivatives].
Topics: Acetohexamide; Adult; Carbutamide; Chlorpropamide; Diabetes Mellitus; Female; Humans; Hypoglycemic Agents; Male; Time Factors; Tolbutamide | 1970 |
Long term observations with oral hypoglycemic drugs: sulphonylureas, biguanides and their combination.
Topics: Administration, Oral; Adult; Age Factors; Aged; Biguanides; Carbutamide; Chlorpropamide; Diabetes Mellitus; Diet; Drug Combinations; Female; Follow-Up Studies; Humans; Male; Middle Aged; Phenformin; Sulfonylurea Compounds; Time Factors; Tolbutamide | 1970 |
A quantum chemical study with special reference to the sulfamyl group of sulfonylureas.
Topics: Acetohexamide; Carbutamide; Chlorpropamide; Humans; Hypoglycemic Agents; Quantum Theory; Sulfones; Sulfonylurea Compounds; Tolazamide; Tolbutamide | 1970 |
[Glibenclamide in the treatment of diabetes].
Topics: Administration, Oral; Adult; Age Factors; Aged; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Female; Glycosuria; Humans; Middle Aged; Time Factors; Tolbutamide; Urea | 1971 |
Anaphylactic reaction to chlorpropamide.
Topics: Anaphylaxis; Antibodies; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Humans; Hyperglycemia; Immunoglobulin E; Male; Middle Aged; Skin Tests; Tolbutamide; Urticaria | 1971 |
[Diabetes mellitus. XII. Oral diabetes therapy].
Topics: Administration, Oral; Biguanides; Carbutamide; Chlorpropamide; Diabetes Mellitus; Humans; Hypoglycemic Agents; Insulin; Obesity; Tolbutamide | 1971 |
[Oral antidiabetics in pregnancy].
Topics: Abnormalities, Drug-Induced; Biguanides; Carbutamide; Chlorpropamide; Female; Fetus; Humans; Hypoglycemic Agents; Infant, Newborn; Insulin; Pregnancy; Pregnancy in Diabetics; Time Factors; Tolbutamide | 1971 |
Distribution of tolbutamide and chlorpropamide after administration to non-diabetic rats.
Topics: Animals; Autoradiography; Chlorpropamide; Diaphragm; Injections, Intravenous; Insulin; Kidney; Liver; Male; Muscles; Myocardium; Pancreas; Rats; Sulfur Isotopes; Tolbutamide | 1971 |
Effects of various drugs on insulin antibodies.
Topics: Animals; Antibodies; Antineoplastic Agents; Bromouracil; Chlorambucil; Chlorpropamide; Complement Fixation Tests; Cyclophosphamide; Dactinomycin; Diaphragm; Diethylstilbestrol; Drug Synergism; Female; Fluorouracil; Gonadal Steroid Hormones; Guinea Pigs; Hydrocortisone; Injections, Intraperitoneal; Injections, Subcutaneous; Insulin Antibodies; Male; Mercaptopurine; Methotrexate; Neutralization Tests; Phenformin; Testosterone; Tolbutamide; Triazines | 1971 |
Effects of anti-diabetic therapy on certain serum lipid fractions.
Topics: Adolescent; Adult; Chlorpropamide; Diabetes Mellitus; Diet Therapy; Humans; Hypoglycemic Agents; Insulin; Lipids; Middle Aged; Tolbutamide | 1967 |
Pharmacological studies on hypoglycemic sulphonylureas.
Topics: Animals; Cats; Chlorpropamide; Female; Guinea Pigs; Hypoglycemic Agents; Male; Rabbits; Rats; Tolbutamide | 1967 |
[On the oral therapy of diabetes with oradian and chlorpropamide].
Topics: Aged; Carbutamide; Chlorpropamide; Diabetes Mellitus; Diet Therapy; Glycosuria; Humans; Hypoglycemic Agents; Insulin; Middle Aged; Tolbutamide | 1967 |
[Our experiences in treatment of diabetes mellitus].
Topics: Chlorpropamide; Diabetes Mellitus; Diet Therapy; Female; Humans; Insulin; Male; Tolbutamide; Yugoslavia | 1967 |
Oral therapy for diabetes.
Topics: Chlorpropamide; Diabetes Mellitus; Humans; Hypoglycemic Agents; Tolbutamide | 1967 |
Effects of sulfonylurea drugs on the thyroid and serum protein binding of thyroxine in the rat.
Topics: Acetohexamide; Animals; Blood Proteins; Body Weight; Carbutamide; Chlorpropamide; Diiodotyrosine; Iodides; Iodine; Iodine Isotopes; Iodoproteins; Male; Propylthiouracil; Protein Binding; Rats; Thyroid Gland; Thyroxine; Tolbutamide; Triiodothyronine; Tyrosine | 1968 |
Combinations of oral hypoglycemic drugs in obese, insulin-resistant diabetics.
Topics: Adult; Aged; Blood Glucose; Carbohydrate Metabolism; Chlorpropamide; Diabetes Mellitus; Drug Synergism; Female; Glycosuria; Humans; Insulin; Insulin Antibodies; Insulin Resistance; Insulin, Isophane; Insulin, Long-Acting; Male; Middle Aged; Obesity; Phenformin; Tolbutamide | 1968 |
Biochemical basis of the sulfonylurea-induced antabuse syndrome.
Topics: Acetaldehyde; Animals; Chlorpropamide; Drug Synergism; Ethanol; Guinea Pigs; Hypoglycemic Agents; Male; Monoamine Oxidase; Oxidoreductases; Serotonin; Tolbutamide | 1968 |
The antidipsic effect of sulphonamides implanted in the hypothalamus of rats.
Topics: Acetazolamide; Animals; Chlorothiazide; Chlorpropamide; Depression, Chemical; Drinking Behavior; Hydrochlorothiazide; Hypothalamo-Hypophyseal System; Hypothalamus; Rats; Sulfadiazine; Sulfonamides; Thirst; Tolbutamide; Vasopressins; Water | 1968 |
[Severe hypoglycemia reactions following treatment with tolbutamide, carbutamide and chlorpropamide (report on 14 cases, studies on clinical symptoms and pathogenesis)].
Topics: Adult; Aged; Carbutamide; Chlorpropamide; Female; Humans; Hypoglycemia; Hypoglycemic Agents; Male; Middle Aged; Time Factors; Tolbutamide | 1968 |
[Effect of sulfonylureas on lipid levels in diabetic patients].
Topics: Adult; Aged; Chlorpropamide; Diabetes Mellitus; Drug Hypersensitivity; Fatty Acids, Nonesterified; Humans; Insulin; Middle Aged; Tolbutamide; Triglycerides | 1968 |
[A new hypoglycemic sulfonamide: AN1324].
Topics: Age Factors; Blood Glucose; Carbutamide; Chlorpropamide; Diabetes Mellitus; Humans; Hypoglycemic Agents; Sulfonamides; Thiazoles; Time Factors; Tolbutamide | 1968 |
[Treatment of diabetes mellitus with metformin].
Topics: Adult; Aged; Body Weight; Chlorpropamide; Diabetes Mellitus; Drug Synergism; Female; Humans; Male; Metformin; Middle Aged; Tolbutamide | 1968 |
Antidiuretic action of chlorpropamide and tolbutamide.
Topics: Adult; Chlorpropamide; Diuresis; Glomerular Filtration Rate; Humans; Male; Tolbutamide; Vasopressins | 1969 |
The inhibition in vitro of hepatic protein biosynthesis by various oral hypoglycemic agents--site of action.
Topics: Animals; Carbon Isotopes; Chlorpropamide; Female; Hypoglycemic Agents; In Vitro Techniques; Leucine; Liver; Lysine; Microsomes; Phenformin; Phenylalanine; Protein Biosynthesis; Rats; RNA, Transfer; Time Factors; Tolbutamide | 1969 |
Oral hypoglycaemic drugs.
Topics: Acetohexamide; Animals; Chlorpropamide; Guinea Pigs; Humans; Hypoglycemic Agents; Metformin; Phenformin; Tolbutamide | 1969 |
Single and combined drug therapy of sulfonylurea failure.
Topics: Acetohexamide; Aged; Chlorpropamide; Diabetes Mellitus; Humans; Hypoglycemic Agents; Middle Aged; Phenformin; Tolbutamide | 1969 |
Clinical evaluation of the effect of glyclopyramide in diabetes mellitus.
Topics: Adult; Age Factors; Aged; Animals; Blood Glucose; Carbohydrates; Chlorpropamide; Cholesterol; Diabetes Mellitus; Dogs; Female; Gastrointestinal Diseases; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Lipids; Liver Function Tests; Male; Middle Aged; Obesity; Pancreas; Tolbutamide | 1969 |
[Experimental animal studies of sulfonylureas on adrenal medulla and adrenal cortex].
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenal Medulla; Animals; Ascorbic Acid; Blood Glucose; Carbutamide; Catecholamines; Chlorpropamide; Corticosterone; Depression, Chemical; Male; Rats; Stimulation, Chemical; Tolbutamide | 1969 |
The adrenal cortex and the pregnant diabetic.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Glands; Adult; Chlorpropamide; Diabetes Mellitus; Diet Therapy; Female; Glucose Tolerance Test; Humans; India; Insulin; Pituitary-Adrenal Function Tests; Pregnancy; Pregnancy in Diabetics; Racial Groups; Time Factors; Tolbutamide | 1969 |
Yet another sulphonylurea for late-onset diabetics.
Topics: Age Factors; Animals; Chlorpropamide; Diabetes Mellitus; Humans; Hypoglycemic Agents; Mice; Tolbutamide; Urea | 1969 |
Pharmacological fibrinolysis.
Topics: Aged; Androsterone; Anticholesteremic Agents; Butyrates; Chlorpropamide; Coronary Disease; Ethylestrenol; Female; Fibrinogen; Fibrinolysis; Humans; Intermittent Claudication; Male; Metformin; Middle Aged; Phenformin; Platelet Adhesiveness; Tolbutamide | 1969 |
Role of phenformin (DBI) as an adjuvant in oral antidiabetic therapy.
Topics: Acetohexamide; Chlorpropamide; Diabetes Mellitus; Humans; Phenformin; Tolbutamide | 1965 |
Diabetes mellitus in Lebanon. A retrospective clinical study of 560 patients.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Chlorpropamide; Diabetes Mellitus; Female; Humans; Infant; Infant, Newborn; Lebanon; Male; Middle Aged; Retrospective Studies; Tolbutamide | 1965 |
[Chlorpropamide and tolbutamide test in the diagnosis of diabetes mellitus].
Topics: Chlorpropamide; Diabetes Mellitus; Diagnosis, Differential; Humans; Tolbutamide | 1965 |
Comparison of acetohexamide with other sulfonylurea compounds in the treatment of diabetes mellitus.
Topics: Acetohexamide; Aged; Carbutamide; Chlorpropamide; Diabetes Mellitus; Humans; Hypoglycemic Agents; Middle Aged; Tolbutamide | 1965 |
The treatment of diabetes mellitus with oral hypoglycaemic drugs.
Topics: Chlorpropamide; Diabetes Mellitus; Humans; Hypoglycemic Agents; Metformin; Phenformin; Tolbutamide | 1965 |
L-leucine in secondary sulfonylurea failure.
Topics: Aged; Chlorpropamide; Diabetes Mellitus; Female; Humans; In Vitro Techniques; Leucine; Male; Middle Aged; Tolbutamide | 1966 |
Complications in the use of oral hypoglycemic agents.
Topics: Chlorpropamide; Humans; Phenformin; Tolbutamide | 1966 |
Study of liver functions in cases of diabetes mellitus receiving sulphonylureas.
Topics: Adult; Aged; Chlorpropamide; Diabetes Mellitus; Female; Humans; Liver; Liver Function Tests; Male; Middle Aged; Tolbutamide | 1966 |
Diabetes mellitus treated with chlorpropamide and tolbutamide. A four-year clinical study.
Topics: Aged; Alkaline Phosphatase; Biopsy; Blood Protein Electrophoresis; Body Weight; Chlorpropamide; Diabetes Mellitus; Female; Humans; Liver; Male; Middle Aged; Tolbutamide | 1966 |
Effect of insulin, chlorpropamide and tolbutamide on the metabolism of branched chain amino acids.
Topics: Animals; Chlorpropamide; In Vitro Techniques; Insulin; Isoleucine; Leucine; Rabbits; Rats; Tolbutamide; Valine | 1966 |
The clinical value of the glucogram and a new approach to the intravenous glucose tolerance test.
Topics: Adolescent; Adult; Aged; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Female; Glucose Tolerance Test; Humans; Hypoglycemia; Hypoglycemic Agents; Injections, Intravenous; Insulin; Male; Methods; Middle Aged; Tolbutamide | 1966 |
[Suicide by means of oral antidiabetics (sulfonylurea products)].
Topics: Adult; Carbutamide; Chlorpropamide; Female; Humans; Hypoglycemia; Hypoglycemic Agents; Male; Middle Aged; Suicide; Tolbutamide | 1966 |
Tocopherol storage and depletion in adipose tissue and plasma of normal and diabetic human subjects.
Topics: Adipose Tissue; Adult; Aged; Chlorpropamide; Diabetes Mellitus; Diet; Female; Humans; Male; Middle Aged; Tolbutamide; Vitamin E | 1967 |
Secondary failure to sulphonylureas in the treatment of diabetes.
Topics: Carbutamide; Chlorpropamide; Diabetes Mellitus; Drug Tolerance; Humans; Leucine; Tolbutamide | 1967 |
The effects of three oral hypoglycemic agents on the incorporation of leucine-C14 into protein by liver microsomes of normal and alloxan-diabetic rats.
Topics: Animals; Biguanides; Carbon Isotopes; Chlorpropamide; Diabetes Mellitus, Experimental; Female; Leucine; Liver; Microsomes; Proteins; Rats; Tolbutamide | 1967 |
Effect of hypoglycemic agents on liver regeneration.
Topics: Acetohexamide; Animals; Body Weight; Carbutamide; Chlorpropamide; Glucagon; Hypoglycemia; Hypoglycemic Agents; Insulin; Liver Regeneration; Male; Necrosis; Phenformin; Rats; Sulfonylurea Compounds; Tolbutamide | 1967 |
The use and abuse of oral hypoglycemic agents.
Topics: Acetohexamide; Biguanides; Chlorpropamide; Humans; Hypoglycemic Agents; Tolazamide; Tolbutamide | 1967 |
Metabolic effects of hypoglycemic sulfonylureas. I. In vitro effect of sulfonylureas on leucine incorporation and metabolism and on respiration of rat tissues.
Topics: Adipose Tissue; Animals; Carbon Isotopes; Carbutamide; Chlorpropamide; Diaphragm; Hypoglycemic Agents; In Vitro Techniques; Kidney; Leucine; Liver; Male; Muscle Proteins; Muscles; Oxygen Consumption; Protein Biosynthesis; Rats; Tolbutamide | 1967 |
Metabolic effects of hypoglycemic sulfonylureas. II. In vitro effect of sulfonylureas on cell-free protein synthesis and energy metabolism in rat tissues.
Topics: Acetates; Adenosine Triphosphate; Adipose Tissue; Animals; Carbon Isotopes; Carbutamide; Cell-Free System; Chlorpropamide; Citric Acid Cycle; Diaphragm; Fructose; Glucose; Hypoglycemic Agents; In Vitro Techniques; Kidney; Liver; Microsomes; Mitochondria, Liver; Muscles; Oxidative Phosphorylation; Protein Biosynthesis; Rats; Succinates; Tolbutamide | 1967 |
Systemic contact dermatitis from Orinase and Diabinese in diabetics with para-amino hypersensitivity.
Topics: Adult; Benzocaine; Chlorpropamide; Diabetes Complications; Drug Eruptions; Female; Humans; Male; Middle Aged; Sulfanilamides; Tolbutamide | 1982 |
Glibenclamide is exceptional among hypoglycaemic sulphonylureas in accumulating progressively in beta-cell-rich pancreatic islets.
Topics: Animals; Carbutamide; Chlorpropamide; Glipizide; Glyburide; Islets of Langerhans; Mice; Mice, Obese; Sulfonylurea Compounds; Tolbutamide | 1984 |
Sulfonylureas enhance in vivo the effectiveness of insulin in type 1 (insulin dependent) diabetes mellitus.
Topics: Adolescent; Adult; Chlorpropamide; Diabetes Mellitus, Type 1; Drug Interactions; Female; Glipizide; Humans; Insulin; Male; Sulfonylurea Compounds; Tolbutamide | 1984 |
Clinical pharmacology of glipizide.
Topics: Biological Availability; Blood Glucose; Chlorpropamide; Diabetes Mellitus, Type 2; Glipizide; Glyburide; Half-Life; Humans; Kinetics; Structure-Activity Relationship; Sulfonylurea Compounds; Tolbutamide | 1983 |
Metabolic interactions of aldehyde dehydrogenase with therapeutic and toxic agents.
Topics: Alcohol Oxidoreductases; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Animals; Anti-Bacterial Agents; Benserazide; Carbon Tetrachloride; Chlorpropamide; Cyanamide; Disulfiram; Humans; Isoenzymes; Lactams; Liver; Malondialdehyde; Metronidazole; Pargyline; Pharmaceutical Preparations; Propranolol; Pyrogallol; Tolbutamide | 1982 |
Kinetics-effect relations of glipizide and other sulfonylureas.
Topics: Blood Glucose; Chlorpropamide; Diabetes Mellitus; Dose-Response Relationship, Drug; Fasting; Feeding Behavior; Glipizide; Glyburide; Humans; Kidney; Sulfonylurea Compounds; Tolbutamide | 1980 |
Comparative single-dose kinetics and effects of four sulfonylureas in healthy volunteers.
Topics: Adult; Blood Glucose; Chlorpropamide; Fasting; Glipizide; Glyburide; Humans; Insulin; Kinetics; Male; Sulfonylurea Compounds; Time Factors; Tolbutamide | 1980 |
The pharmacology of sulfonylureas.
Topics: Acetohexamide; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Glyburide; Humans; Insulin; Sulfonylurea Compounds; Tolazamide; Tolbutamide | 1981 |
Chlorpropamide- and tolbutamide-alcohol flushing in non-insulin-dependent diabetes.
Topics: Alcoholic Beverages; Chlorpropamide; Diabetes Mellitus; Drug Interactions; Erythema; Face; Humans; Male; Middle Aged; Skin Temperature; Tolbutamide | 1981 |
Carbenoxolone interactions in man--preliminary report.
Topics: Carbenoxolone; Chlorpropamide; Drug Interactions; Glycyrrhetinic Acid; Half-Life; Humans; Phenytoin; Protein Binding; Stomach Ulcer; Tolbutamide; Warfarin | 1980 |
High-performance liquid chromatographic assay of tolbutamide and carboxytolbutamide in human plasma.
Topics: Chlorpropamide; Chromatography, High Pressure Liquid; Drug Stability; Humans; Spectrophotometry, Ultraviolet; Tolbutamide | 1981 |
Effects of chlorpropamide and tolbutamide on adenylate cyclase activity in rat heart and liver.
Topics: Adenylyl Cyclase Inhibitors; Animals; Chlorpropamide; Epinephrine; Female; Glucagon; In Vitro Techniques; Liver; Myocardium; Rats; Rats, Inbred Strains; Tolbutamide | 1981 |
Hypoglycemia from the inadvertent use of oral hypoglycemic agents.
Topics: Adolescent; Aged; Chlorpropamide; Female; Humans; Hypoglycemia; Hypoglycemic Agents; Medication Errors; Sulfonylurea Compounds; Tolbutamide | 1980 |
Nuclear magnetic resonance study of the binding of tolbutamide and chlorpropamide to bovine serum albumin.
Topics: Acetylation; Animals; Cattle; Chlorpropamide; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Protein Binding; Serum Albumin, Bovine; Tolbutamide | 1980 |
Chlorpropamide-alcohol flushing is not useful for individual genetic counseling of diabetic patients.
Topics: Adolescent; Adult; Blushing; C-Peptide; Child; Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Ethanol; Genetic Counseling; Humans; Middle Aged; Risk; Tolbutamide | 1980 |
Comparative placental transport of oral hypoglycemic agents in humans: a model of human placental drug transfer.
Topics: Administration, Oral; Analysis of Variance; Antipyrine; Biological Transport; Chlorpropamide; Chromatography, High Pressure Liquid; Female; Glipizide; Glyburide; Humans; Hypoglycemic Agents; Maternal-Fetal Exchange; Models, Biological; Molecular Weight; Placenta; Pregnancy; Regression Analysis; Tolbutamide | 1994 |
Administration of sulfonylureas can increase glucose-induced insulin secretion for decades in patients with maturity-onset diabetes of the young.
Topics: Adolescent; Adult; Age Factors; Blood Glucose; Child; Chlorpropamide; Chromosomes, Human, Pair 20; Diabetes Mellitus, Type 2; Diet, Diabetic; Follow-Up Studies; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Kinetics; Prospective Studies; Time Factors; Tolbutamide | 1993 |
Use of tolbutamide as a substrate probe for human hepatic cytochrome P450 2C9.
Topics: Aryl Hydrocarbon Hydroxylases; Chlorpropamide; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Humans; Hypoglycemic Agents; In Vitro Techniques; Microsomes, Liver; Molecular Probes; Reproducibility of Results; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Substrate Specificity; Tolbutamide | 1996 |
Photohemolytic potency of oral antidiabetic drugs in vitro: effects of antioxidants and a nitrogen atmosphere.
Topics: Antioxidants; Ascorbic Acid; Carbutamide; Chlorpropamide; Dose-Response Relationship, Drug; Gliclazide; Glipizide; Glyburide; Hemolysis; Humans; Hypoglycemic Agents; Nitrogen; Radiation-Sensitizing Agents; Reactive Oxygen Species; Sulfonamides; Sulfonylurea Compounds; Superoxide Dismutase; Tolazamide; Tolbutamide; Ultraviolet Rays; Vitamin E | 1996 |
Characterization of acetohexamide reductases purified from rabbit liver, kidney, and heart: structural requirements for substrates and inhibitors.
Topics: Acetohexamide; Alcohol Oxidoreductases; Animals; Binding Sites; Carbutamide; Chlorpropamide; Enzyme Inhibitors; Hypoglycemic Agents; Kidney; Kinetics; Liver; Myocardium; Oxidation-Reduction; Rabbits; Structure-Activity Relationship; Substrate Specificity; Tolbutamide; Triazines | 1997 |
Rates of hypoglycemia in users of sulfonylureas.
Topics: Adult; Aged; Chlorpropamide; Female; Gliclazide; Glipizide; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Incidence; Male; Middle Aged; Poisson Distribution; Risk; Risk Factors; Sulfonylurea Compounds; Surveys and Questionnaires; Time Factors; Tolbutamide | 1997 |
Sulfonylureas stimulate renin secretion from the perfused kidney of the rat.
Topics: Animals; Blood Pressure; Chlorpropamide; Cyclic AMP; Glyburide; Hypoglycemic Agents; In Vitro Techniques; Kidney; Male; Perfusion; Rats; Rats, Wistar; Renin; Stimulation, Chemical; Sulfonylurea Compounds; Tolbutamide | 1999 |
Identification of sulfonylureas in serum by electrospray mass spectrometry.
Topics: Calibration; Chlorpropamide; Chromatography, Liquid; Glipizide; Glyburide; Humans; Mass Spectrometry; Models, Chemical; Sulfonylurea Compounds; Tolbutamide; Ultraviolet Rays | 2000 |
Relative potencies of chlorpropamide and tolbutamide in man.
Topics: Chlorpropamide; Hypoglycemic Agents; Tolbutamide | 1959 |
Some effects of tolbutamide and chlorpropamide in vitro.
Topics: Chlorpropamide; Hypoglycemic Agents; In Vitro Techniques; Tolbutamide | 1959 |
A comparison of the acute hypoglycemic potencies of tolbutamide and chlorpropamide.
Topics: Chlorpropamide; Hypoglycemic Agents; Tolbutamide | 1959 |
Use of chlorpropamide in diabetes mellitus in usual diabetic patients and in primary and secondary tolbutamide failures.
Topics: Chlorpropamide; Diabetes Mellitus; Humans; Hypoglycemic Agents; Tolbutamide | 1959 |
Experiences with tolbutamide and chlorpropamide in tuberculous diabetic patients.
Topics: Chlorpropamide; Diabetes Mellitus; Hypoglycemic Agents; Tolbutamide; Tuberculosis; Tuberculosis, Pulmonary | 1959 |
A clinical comparison of chlorpropamide and tolbutamide.
Topics: Chlorpropamide; Hypoglycemic Agents; Tolbutamide | 1959 |
Clinical experiences with chlorpropamide, with special reference to comparison with previous experience with carbutamide and tolbutamide.
Topics: Carbutamide; Chlorpropamide; Humans; Hypoglycemic Agents; Tolbutamide | 1959 |
The effects of tolbutamide and chlorpropamide on patients exhibiting jaundice as a result of previous chlorpropamide therapy.
Topics: Chlorpropamide; Humans; Hypoglycemic Agents; Jaundice; Tolbutamide | 1959 |
Advantages and disadvantages in shifting patients from tolbutamide to chlorpropamide.
Topics: Chlorpropamide; Humans; Hypoglycemic Agents; Tolbutamide | 1959 |
Comparative hypoglycemic effects of chlorpropamide, tolbutamide, and furfurylurea.
Topics: Chlorpropamide; Furans; Hypoglycemic Agents; Tolbutamide; Urea | 1959 |
The comparative pharmacology of tolbutamide, carbutamide, chlorpropamide and metahexamide in man.
Topics: Carbutamide; Chlorpropamide; Humans; Hypoglycemic Agents; Male; Sulfonylurea Compounds; Tolbutamide | 1959 |
Comparison of relative hypoglycemic potencies and metabolic effects of metahexamide, chlorpropamide and tolbutamide in diabetes mellitus.
Topics: Blood Glucose; Chlorpropamide; Diabetes Mellitus; Humans; Hypoglycemic Agents; Sulfonylurea Compounds; Tolbutamide | 1959 |
A clinical comparison of tolbutamide, chlorpropamide and metahexamide in the treatment of diabetes.
Topics: Chlorpropamide; Diabetes Mellitus; Hypoglycemic Agents; Sulfonylurea Compounds; Tolbutamide | 1959 |
[Oral hypoglycemic drugs; comparative study of carbutamide, tolbutamide and chlorpropamide].
Topics: Carbutamide; Chlorpropamide; Humans; Hypoglycemic Agents; Tolbutamide | 1961 |
Clinical studies with tolbutamide and chlorpropamide.
Topics: Biomedical Research; Chlorpropamide; Hypoglycemic Agents; Tolbutamide | 1960 |
[Advantages and disadvantages on the transfer of diabetics from rastinon to diabinese].
Topics: Chlorpropamide; Diabetes Mellitus; Hypoglycemic Agents; Tolbutamide | 1960 |
[Oral antidiabetics as substitutes for small insulin doses in psychiatric patients. A clinical trial with chlorpropamide and tolbutamide].
Topics: Chlorpropamide; Counseling; Electroconvulsive Therapy; Humans; Hypoglycemic Agents; Insulin; Mental Disorders; Psychotherapy; Tolbutamide | 1960 |
Comparison of acute hypoglycemic potencies of tolbutamide and chlorpropamide.
Topics: Chlorpropamide; Hypoglycemic Agents; Tolbutamide | 1960 |
[Experiences in the treatment of diabetes with the oral drugs rastinon, diabinese and dibein].
Topics: Chlorpropamide; Diabetes Mellitus; Hypoglycemic Agents; Oral Medicine; Tolbutamide | 1960 |
Clinical experience with chlorpropamide and comparative evaluation with tolbutamide.
Topics: Chlorpromazine; Chlorpropamide; Humans; Tolbutamide | 1960 |
[Behavior of the blood sugar and phosphorus levels during the glucose tolerance test before and after the administration of carbutamide, tolbutamide and chlorpropamide].
Topics: Blood Glucose; Carbutamide; Chlorpropamide; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Phosphorus; Phosphorus, Dietary; Tolbutamide | 1959 |
Chlorpropamide (diabinese) in diabetes, with special reference to tolbutamide-failed cases.
Topics: Chlorpropamide; Diabetes Mellitus; Hypoglycemic Agents; Tolbutamide | 1960 |
[Comparative hypoglycemic effect of sulfonamide mixtures. Carbutamide (BZ-55), tolbutamide (D-860). chlorpropamide (P-607). in patients with diabetes mellitus].
Topics: Carbutamide; Chlorpropamide; Diabetes Mellitus; Humans; Hypoglycemic Agents; Sulfonamides; Tolbutamide | 1959 |
Oral hypoglycemic agents in the treatment of diabetes mellitus. A review of clinical experience with chlorpropamide, tolbutamide, and phenethvlbiguanide.
Topics: Chlorpropamide; Diabetes Mellitus; Hypoglycemic Agents; Tolbutamide | 1961 |
Physiology of fibrinolysis.
Topics: Chlorpropamide; Fibrinolysis; Tolbutamide | 1961 |
Tolbutamide and chlorpropamide during pregnancy in human diabetics.
Topics: Carbutamide; Chlorpropamide; Diabetes Mellitus; Female; Pregnancy; Pregnancy Complications; Tolbutamide | 1962 |
[Action of hypoglycemic drugs on the stomach].
Topics: Chlorpropamide; Gastric Acidity Determination; Hypoglycemic Agents; Phenformin; Stomach; Tolbutamide | 1963 |
Identification test for tolbutamide and chlorpropamide.
Topics: Chemistry, Pharmaceutical; Chlorpropamide; Pharmacy; Tolbutamide | 1962 |
A fundamental approach to hypoglycemic therapy.
Topics: Chlorpropamide; Hypoglycemic Agents; Insulin; Phenformin; Tolbutamide | 1963 |
Alterations in fibrinolytic parameters of subjects with diabetes mellitus.
Topics: Chlorpropamide; Diabetes Mellitus; Fibrinolysis; Humans; Insulin; Thrombolytic Therapy; Tolbutamide | 1963 |
Oral treatment of diabetes.
Topics: Administration, Oral; Carbutamide; Chlorpropamide; Diabetes Mellitus; Humans; Tolbutamide | 1959 |
Protein interactions of sulfonylurea compounds.
Topics: Blood Proteins; Chlorpropamide; Humans; Sulfonylurea Compounds; Tolbutamide | 1962 |
Clinical experience with sulphonylureas.
Topics: Carbutamide; Chlorpropamide; Humans; Sulfonylurea Compounds; Tolbutamide | 1962 |
Oral hypoglycemic agents.
Topics: Chlorpropamide; Humans; Hypoglycemic Agents; Phenformin; Tolbutamide | 1963 |
THE TREATMENT OF DIABETES WITH ORAL DRUGS AND DIET.
Topics: Chlorpropamide; Diabetes Mellitus; Diet; Diet, Reducing; Obesity; Phenformin; Phenmetrazine; Tolbutamide | 1963 |
PROTRACTED TOLBUTAMIDE HYPOGLYCEMIA.
Topics: Chlorpropamide; Coma; Diabetes Mellitus; Geriatrics; Hypoglycemia; Liver Cirrhosis; Multiple Sclerosis; Tolbutamide; Toxicology | 1963 |
METABOLISM OF THE ALLOXAN DIABETIC RAT RETINA.
Topics: Adrenalectomy; Alloxan; Animals; Chlorpropamide; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Hypophysectomy; Metabolism; Phenformin; Rats; Research; Retina; Tolbutamide | 1964 |
STUDIES IN GLYCOSURIA AND DIABETES IN NON-WHITE POPULATIONS OF THE TRANSVAAL. I. AFRICANS.
Topics: Black People; Chlorpropamide; Diabetes Mellitus; Diet; Glycosuria; Health Surveys; Hemochromatosis; Humans; Insulin; Iron Isotopes; Obesity; Tolbutamide | 1963 |
DIABETES MELLITUS IN THE RHODESIAN AFRICAN.
Topics: Adolescent; Child; Chlorpropamide; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Coma; Diabetic Neuropathies; Diabetic Retinopathy; Geriatrics; Humans; Hypertension; Insulin; Tolbutamide; Zimbabwe | 1963 |
HISTOLOGICAL CHANGES IN NORMAL AND ALLOXANIZED RATS WITH PROLONGED ADMINISTRATION OF SULFONYLUREAS.
Topics: Adrenal Glands; Animals; Carbutamide; Chlorpropamide; Diabetes Mellitus, Experimental; Islets of Langerhans; Liver; Pathology; Pharmacology; Pituitary Gland; Rats; Research; Tolbutamide | 1963 |
[DIABETIC RETINOPATHY AND ITS TREATMENT].
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Anabolic Agents; Arteriosclerosis; Carbutamide; Chlorpropamide; Diabetic Retinopathy; Humans; Hypophysectomy; Phenformin; Pituitary Irradiation; Steroids; Testosterone Congeners; Tolbutamide | 1963 |
THE VISCERA IN SULFONYLUREA-TREATED DIABETICS.
Topics: Chlorpropamide; Diabetes Mellitus; Granuloma; Heart Diseases; Insulin; Kidney Diseases; Liver Diseases; Myocarditis; Nephritis; Nephritis, Interstitial; Pathology; Sulfonylurea Compounds; Tolbutamide; Viscera | 1963 |
[ORAL DIABETIC DRUGS].
Topics: Carbutamide; Chlorpropamide; Diabetes Mellitus; Female; Humans; Metformin; Phenformin; Pregnancy; Pregnancy in Diabetics; Tolbutamide | 1964 |
ORAL TREATMENT OF DIABETES MELLITUS.
Topics: Administration, Oral; Chlorpropamide; Diabetes Mellitus; Hypoglycemic Agents; Pharmacology; Phenformin; Prognosis; Statistics as Topic; Tolbutamide; Toxicology | 1964 |
[THE INFLUENCE OF PLASMA UPON THE GLUCOSE UPTAKE OF ERYTHROCYTES IN VARIOUS DISEASES WITH GLYCOSURIA. 2. CHANGES IN THE INFLUENCE OF PLASMA UPON THE GLUCOSE UPTAKE OF ERYTHROCYTES IN TREATED DIABETES MELLITUS].
Topics: Blood Chemical Analysis; Blood Glucose; Carbohydrate Metabolism; Chlorpropamide; Diabetes Mellitus; Erythrocytes; Glycosuria; Humans; Hypoglycemic Agents; Insulin; Plasma; Tolbutamide | 1963 |
[VARIANTS OF THE PRE-DIABETIC STATE IN PREGNANCY].
Topics: Chlorpropamide; Diabetes Mellitus; Female; Prediabetic State; Pregnancy; Pregnancy in Diabetics; Prognosis; Tolbutamide | 1963 |
MANAGEMENT OF THE NEW DIABETIC PATIENT.
Topics: Chlorpropamide; Diabetes Mellitus; Diet, Diabetic; Disease Management; Humans; Insulin; Phenformin; Tolbutamide | 1964 |
ACETOHEXAMIDE IN TREATMENT OF DIABETES MELLITUS.
Topics: Acetohexamide; Blood Chemical Analysis; Chlorpropamide; Diabetes Mellitus; Diet, Diabetic; Gastroenterology; Geriatrics; Glucose Tolerance Test; Hypoglycemic Agents; Leukopenia; Middle Aged; Tolbutamide; Toxicology | 1964 |
[QUANTITATIVE STUDY OF NEOGENESIS OF THE ISLANDS OF LANGERHANS OF THE PANCREAS INDUCED BY A HYPOGLYCEMIC SULFONAMIDE, TOLBUTAMIDE].
Topics: Chlorpropamide; Hypoglycemic Agents; Islands; Islets of Langerhans; Pancreas; Pharmacology; Rats; Research; Sulfonamides; Tolbutamide | 1963 |
COMBINED TRIAL OF ACETOHEXAMIDE AND TWO DIGUANIDE PREPARATIONS.
Topics: Acetohexamide; Chlorpropamide; Diabetes Mellitus; Geriatrics; Hypoglycemic Agents; Insulin; Metformin; Pharmacology; Phenformin; Tolbutamide; Toxicology | 1964 |
A REVIEW OF THE HISTORY OF THE TREATMENT OF DIABETES MELLITUS AND THE SEARCH FOR ORAL HYPOGLYCAEMIC AGENTS.
Topics: Carbutamide; Chlorpropamide; Diabetes Mellitus; Guanidine; Guanidines; History; Humans; Hypoglycemic Agents; Metformin; Phenformin; Sulfonylurea Compounds; Tolbutamide | 1964 |
[THE PROTECTIVE EFFECT OF ANTIDIABETIC SULFOCARBAMIDES IN THE LIVER].
Topics: Carbon Tetrachloride Poisoning; Carbutamide; Chemical and Drug Induced Liver Injury; Chlorpropamide; Hepatitis; Hypoglycemic Agents; Liver; Liver Function Tests; Rats; Research; Tolbutamide; Toxicology | 1963 |
ORAL HYPOGLYCEMIC AGENTS.
Topics: Chlorpropamide; Diabetes Mellitus; Hypoglycemic Agents; Phenformin; Tolbutamide | 1964 |
[THE THERAPY OF DIABETES MELLITUS].
Topics: Carbutamide; Chlorpropamide; Diabetes Mellitus; Diabetic Coma; Diet, Diabetic; Female; Globins; Hypoglycemic Agents; Insulin; Insulin, Long-Acting; Insulin, Regular, Pork; Metformin; Pregnancy; Pregnancy in Diabetics; Protamines; Surgical Procedures, Operative; Tolbutamide; Toxicology | 1964 |
TWO YEARS' EXPERIENCE WITH ACETOHEXAMIDE.
Topics: Acetohexamide; Alkaline Phosphatase; Blood Chemical Analysis; Chlorpropamide; Coloring Agents; Geriatrics; Hypoglycemic Agents; Liver Function Tests; Massachusetts; Phenformin; Sulfobromophthalein; Sulfonylurea Compounds; Tolbutamide; Toxicology; Transaminases; Urine | 1964 |
ACETOHEXAMIDE: CLINICAL EVALUATION OF A NEW ORAL ANTIDIABETIC AGENT.
Topics: Acetohexamide; Biomedical Research; Chemical Phenomena; Chemistry; Chlorpropamide; Geriatrics; Hypoglycemic Agents; Tolbutamide; Toxicology | 1964 |
THE PHARMACOLOGICAL ENHANCEMENT OF BLOOD FIBRINOLYTIC ACTIVITY WITH SPECIAL REFERENCE TO PHENFORMIN.
Topics: Anabolic Agents; Anticoagulants; Arteriosclerosis Obliterans; Chlorpropamide; Coronary Disease; Fibrinolysis; Humans; Phenformin; Steroids; Thrombolytic Therapy; Tolbutamide | 1964 |
[CONTRIBUTION TO THE STUDY OF THE TOXIC EFFECTS DUE TO HYPOGLYCEMIC SULFONYLUREAS].
Topics: Carbutamide; Chemical and Drug Induced Liver Injury; Chlorpropamide; Diabetes Mellitus; Drug Eruptions; Drug Hypersensitivity; Eosinophilia; Feeding and Eating Disorders; Geriatrics; Hepatitis; Humans; Hypoglycemic Agents; Jaundice; Leukopenia; Nausea; Sulfonylurea Compounds; Tolbutamide; Toxicology | 1964 |
SULPHONYLUREA DRUGS IN PREGNANCY.
Topics: Abnormalities, Drug-Induced; Chlorpropamide; Diabetes Mellitus; Female; Fetal Death; Humans; Pregnancy; Pregnancy in Diabetics; Sulfonylurea Compounds; Tolbutamide; Toxicology | 1964 |
DRUG-INDUCED BLOOD DYSCRASIAS. I. APLASTIC ANEMIA.
Topics: Acetazolamide; Anemia; Anemia, Aplastic; Anticonvulsants; Benzene; Chloramphenicol; Chlorothiazide; Chlorpropamide; Gold; Hematologic Diseases; Hexachlorocyclohexane; Phenylbutazone; Prednisone; Sulfamethoxypyridazine; Sulfisoxazole; Testosterone; Tolbutamide; Toxicology | 1964 |
PHARMACOLOGICAL ENCHANCEMENT OF FIBRINOLYTIC ACTIVITY OF BLOOD.
Topics: Adrenal Cortex Hormones; Anabolic Agents; Arteriosclerosis; Chlorpropamide; Coronary Disease; Fibrinolysis; Heart Block; Humans; Nandrolone; Pharmacology; Phenformin; Prednisone; Steroids; Testosterone; Tolbutamide | 1964 |
[CLINICAL EXPERIENCES WITH A NEW ORAL HYPOGLYCEMIC DRUG, ACETOHEXAMIDE].
Topics: Acetohexamide; Biomedical Research; Chlorpropamide; Diabetes Mellitus; Dogs; Geriatrics; Hypoglycemic Agents; Pharmacology; Rabbits; Rats; Research; Tolbutamide; Toxicology | 1963 |
CLINICAL OBSERVATIONS ON THE USE OF SULFONYLUREAS IN THE TREATMENT OF PSORIASIS AND SOME OTHER DERMATOSES.
Topics: Acne Vulgaris; Blood Glucose; Chlorpropamide; Dermatitis, Seborrheic; Diabetes Mellitus; Drug Therapy; Humans; Hypoglycemia; Parapsoriasis; Psoriasis; Sulfonylurea Compounds; Tolbutamide | 1963 |
[BIOPSY OF THE STOMACH IN THE DIABETIC TREATED WITH HYPOGLYCEMIC DRUGS. COMPARATIVE STUDY].
Topics: Biopsy; Carbutamide; Chlorpropamide; Diabetes Mellitus; Gastric Mucosa; Gastritis; Hypoglycemic Agents; Insulin; Pathology; Stomach; Tolbutamide; Toxicology | 1964 |
ORAL HYPOGLYCEMIC DRUGS.
Topics: Chlorpropamide; Hypoglycemic Agents; Pharmacology; Phenformin; Tolbutamide | 1964 |
CONJOINT CLINIC ON DRUGS AND DIABETES.
Topics: Adrenalectomy; Antihypertensive Agents; Benzothiadiazines; Biomedical Research; Blood; Blood Glucose; Body Weight; Chlorothiazide; Chlorpropamide; Diabetes Mellitus; Diazoxide; Diuretics; Dogs; Hydrochlorothiazide; Hypertension; Hypophysectomy; Nitrogen; Pharmacology; Placebos; Polythiazide; Potassium; Rats; Research; Tolbutamide; Toxicology; Trichlormethiazide; Urea | 1964 |
[ON TOLAZAMIDE: APROPOS OF A NEW HYPOGLYCEMIC SULFANYLUREA AND OF ACQUIRED SULFANYLUREAU RESISTANCE].
Topics: Carbutamide; Chlorpropamide; Diabetes Mellitus; Drug Tolerance; Humans; Hypoglycemic Agents; Insulin; Sulfonylurea Compounds; Tolazamide; Tolbutamide | 1964 |
ACETOHEXAMIDE ('DIMELOR') IN DIABETES.
Topics: Acetohexamide; Biomedical Research; Chlorpropamide; Diabetes Mellitus; Geriatrics; Hypoglycemic Agents; Insulin; Tolbutamide; Toxicology | 1964 |
ORAL HYPOGLYCEMIC DRUGS: COMPARATIVE EVALUATION OF TOLBUTAMIDE, CHLORPROPAMIDE AND PHENFORMIN.
Topics: Alkaline Phosphatase; Biomedical Research; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diet, Diabetic; Female; Humans; Hypoglycemic Agents; Insulin; Obesity; Phenformin; Pregnancy; Pregnancy in Diabetics; Statistics as Topic; Tolbutamide; Toxicology | 1964 |
USE OF ACETOHEXAMIDE (DYMELOR) IN DIABETIC PATIENTS WITH SECONDARY FAILURES TO ANTIDIABETIC DRUGS.
Topics: Acetohexamide; Chlorpropamide; Diabetes Mellitus; Drug Therapy; Hypoglycemic Agents; Phenformin; Tolbutamide | 1964 |
COMPLICATIONS OF THERAPY WITH ORAL HYPOGLYCEMIC AGENTS.
Topics: Acidosis; Chlorpropamide; Diabetes Mellitus; Diabetic Ketoacidosis; Humans; Hypoglycemia; Hypoglycemic Agents; Lactates; Pancreatic Diseases; Phenformin; Tolbutamide; Toxicology | 1964 |
CLINICAL EFFECTS OF A NEW, POTENT, NON-TOXIC SULFONYLUREA (TOLAZAMIDE).
Topics: Biomedical Research; Blood Glucose; Chemical Phenomena; Chemistry; Chlorpropamide; Diabetes Mellitus; Drug Therapy; Humans; Hypoglycemic Agents; Insulin; Pharmacology; Sulfonylurea Compounds; Tolazamide; Tolbutamide; Toxicology | 1964 |
[ACTION OF HYPOGLYCEMIC SULFONAMIDES ON THE PRODUCTION OF CO2 BY ADIPOSE TISSUE OF THE RAT EPIDIDYMIS "IN VITRO"].
Topics: Acetohexamide; Adipose Tissue; Carbon Dioxide; Carbutamide; Chlorpropamide; Epididymis; Humans; Hypoglycemic Agents; In Vitro Techniques; Insulin; Male; Metabolism; Pharmacology; Rats; Research; Sulfanilamide; Sulfanilamides; Sulfonamides; Tolazamide; Tolbutamide | 1964 |
TOLBUTAMIDE-INDUCED HYPOGLYCEMIA.
Topics: Adenocarcinoma; Adenocarcinoma, Papillary; Chlorpropamide; Diabetes Mellitus; Drug Therapy; Female; Genital Neoplasms, Female; Humans; Hypoglycemia; Insulin; Liver Cirrhosis; Multiple Sclerosis; Pancreatic Diseases; Parkinsonian Disorders; Tolbutamide; Toxicology | 1964 |
[OUR EXPERIENCES WITH ORAL ANTIDIABETICS IN OUTPATIENT CONTROL AND TREATMENT OF DIABETIC PATIENTS].
Topics: Carbutamide; Chlorpropamide; Diabetes Mellitus; Diet, Diabetic; Drug Therapy; Guanidines; Hungary; Hypoglycemic Agents; Insulin; Outpatient Clinics, Hospital; Outpatients; Tolbutamide; Toxicology | 1964 |
RECENT ADVANCES AND TRENDS IN DRUG THERAPY. IV. ORAL HYPOGLYCAEMIC AGENTS.
Topics: Acetohexamide; Chlorpropamide; Drug Therapy; Hypoglycemic Agents; Phenformin; Tolbutamide; Toxicology | 1964 |
[CLINICAL PROBLEMS IN THE MATTER OF INSULIN RESISTANCE].
Topics: Adolescent; Chlorpropamide; Diabetes Mellitus; Diagnosis; Drug Tolerance; Hemagglutination; Humans; Immunoelectrophoresis; Insulin; Insulin Antibodies; Insulin Resistance; Radiotherapy; Tolbutamide | 1964 |
ASSESSMENT OF ORAL THERAPY IN DIABETES MELLITUS.
Topics: Biomedical Research; Chlorpropamide; Diabetes Mellitus; Humans; Phenformin; Tolbutamide | 1964 |
[COMPARATIVE STUDIES ON THE IGT, CHLORPROPAMIDE AND TOLBUTAMIDE TEST].
Topics: Biomedical Research; Chlorpropamide; Clinical Laboratory Techniques; Diabetes Mellitus; Glucose Tolerance Test; Humans; Tolbutamide | 1964 |
THE FAMILY DOCTOR AND THE DIABETIC.
Topics: Acidosis; Adolescent; Child; Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Ketoacidosis; Diabetic Neuropathies; Diabetic Retinopathy; Diet, Diabetic; Drug Therapy; Female; Growth; Humans; Hypoglycemia; Insulin; Marriage; Pregnancy; Pregnancy in Diabetics; Puberty; Sexual Maturation; Tolbutamide | 1965 |
SEVERE AND PROLONGED HYPOGLYCEMIC SHOCK DURING SULFONYLUREA TREATMENT.
Topics: Acetohexamide; Chlorpropamide; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Coma; Geriatrics; Hypoglycemia; Hypoglycemic Agents; Intracranial Arteriosclerosis; Kidney Diseases; Pathology; Shock; Sulfonylurea Compounds; Tolbutamide; Toxicology | 1965 |
METABOLISM OF ANTIDIABETIC SULFONYLUREAS IN MAN. I. BIOLOGICAL HALF-LIVES OF THE P-ACETYLBENZENESULFONYLUREAS, U-18536 AND ACETOHEXAMIDE AND THEIR METABOLITES.
Topics: Acetohexamide; Biological Transport; Blood; Chlorpropamide; Fluids and Secretions; Humans; Hypoglycemic Agents; Metabolism; Sulfonylurea Compounds; Tolazamide; Tolbutamide; Urine | 1965 |
CHOLESTATIC JAUNDICE FOLLOWING USE OF SULFONYLUREA DRUGS.
Topics: Chlorpropamide; Diabetes Mellitus; Drug Therapy; Jaundice; Jaundice, Obstructive; Sulfonylurea Compounds; Tolbutamide; Toxicology | 1965 |
HYPOGLYCEMIC COMA DURING SULFONYLUREA THERAPY.
Topics: Carbutamide; Chlorpropamide; Coma; Diabetes Mellitus; Drug Therapy; Geriatrics; Hypoglycemia; Hypoglycemic Agents; Sulfonylurea Compounds; Tolbutamide; Toxicology | 1965 |
TREATMENT OF DIABETIC PATIENTS WITH CHLORPROPAMID AFTER SECONDARY FAILURE ON TOLBUTAMIDE.
Topics: Alkaline Phosphatase; Blood Cell Count; Blood Urea Nitrogen; Chlorpropamide; Diabetes Mellitus; Drug Therapy; Tolbutamide; Toxicology; Urea; Urine | 1965 |
SERUM CONCENTRATION AND URINARY EXCRETION OF ORAL SULFONYLUREA COMPOUNDS: RELATION TO DIABETIC CONTROL.
Topics: Acetohexamide; Biological Transport; Blood Chemical Analysis; Body Fluids; Chlorpropamide; Diabetes Mellitus; Drug Therapy; Fluids and Secretions; Humans; Hypoglycemic Agents; Metabolism; Sulfonylurea Compounds; Tolbutamide; Urine | 1965 |
THE ORAL HYPOGLYCEMIC COMPOUNDS.
Topics: Acetohexamide; Chlorpropamide; Diabetes Mellitus; Drug Therapy; Humans; Hypoglycemic Agents; Phenformin; Tolbutamide; Toxicology | 1965 |
OBSERVATIONS ON CLINICAL PATTERNS OF DIABETES MELLITUS IN INDIA.
Topics: Acidosis; Aging; Body Height; Body Weight; Carbutamide; Chlorpropamide; Diabetes Mellitus; Diabetic Ketoacidosis; Diet, Diabetic; Drug Therapy; Epidemiology; Humans; India; Insulin; Statistics as Topic; Tolbutamide | 1965 |
SPONTANEOUS DIABETES MELLITUS IN DOGS.
Topics: Animals; Chlorpropamide; Diabetes Mellitus; Diagnosis; Dog Diseases; Dogs; Drug Therapy; Insulin; Insulin, Isophane; Insulin, Long-Acting; Pathology; Phenformin; Protamines; Tolbutamide | 1965 |
ORAL THERAPY FOR DIABETES MELLITUS.
Topics: Acetohexamide; Chlorpropamide; Diabetes Mellitus; Drug Therapy; Glucose; Hypoglycemic Agents; Pharmacology; Phenformin; Tolbutamide | 1965 |
HYPOTHYROIDISM IN DIABETICS TREATED WITH SULPHONYLUREA.
Topics: Biguanides; Chlorpropamide; Diabetes Mellitus; Diet, Diabetic; Drug Therapy; Guanidines; Hypothyroidism; Insulin; Statistics as Topic; Sulfonylurea Compounds; Tolbutamide; Toxicology | 1965 |
Some observations on the use of chlorpropamide in primary tolbutamide-failure diabetics.
Topics: Chlorpropamide; Diabetes Mellitus; Hypoglycemic Agents; Tolbutamide | 1960 |
Depth profiling of compression-induced disorders and polymorphic transition on tablet surfaces with grazing incidence X-ray diffraction.
Topics: Carbamazepine; Chemistry, Pharmaceutical; Chlorpropamide; Drug Compounding; Isomerism; Pharmaceutical Preparations; Pressure; Surface Properties; Tablets; Tolbutamide; X-Ray Diffraction | 2006 |
Pharmacogenomic analysis of ATP-sensitive potassium channels coexpressing the common type 2 diabetes risk variants E23K and S1369A.
Topics: ATP-Binding Cassette Transporters; Chlorpropamide; Cyclohexanes; Diabetes Mellitus, Type 2; Gene Expression Regulation; Gliclazide; Glyburide; Haplotypes; Homozygote; Humans; Isoindoles; Nateglinide; Patch-Clamp Techniques; Phenylalanine; Polymorphism, Single Nucleotide; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Structure-Activity Relationship; Sulfonylurea Compounds; Sulfonylurea Receptors; Tolbutamide | 2012 |
Mechanosynthesis of pharmaceutically relevant sulfonyl-(thio)ureas.
Topics: Catalysis; Chlorpropamide; Copper; Glyburide; Hypoglycemic Agents; Isothiocyanates; Molecular Structure; Sulfonamides; Tolbutamide | 2014 |
Modulated Protein Binding Ability of Anti-Diabetic Drugs in Presence of Monodispersed Gold Nanoparticles and its Inhibitory Potential towards Advanced Glycated End (AGE) Product Formation.
Topics: Adsorption; Animals; Binding Sites; Cattle; Chlorpropamide; Colloids; Glycation End Products, Advanced; Gold; Hydrophobic and Hydrophilic Interactions; Hypoglycemic Agents; Metal Nanoparticles; Particle Size; Serum Albumin, Bovine; Spectrometry, Fluorescence; Surface Properties; Temperature; Tolbutamide | 2020 |
Applicability of capillary electrophoresis-frontal analysis for displacement studies: Effect of several drugs on l-tryptophan and lidocaine binding to human serum albumin.
Topics: Binding Sites; Chlorpropamide; Diclofenac; Electrophoresis, Capillary; Flurbiprofen; Humans; Ibuprofen; Lidocaine; Phenylbutazone; Serum Albumin, Human; Tolbutamide; Tryptophan | 2020 |
Implications of Coexistent Halogen and Hydrogen Bonds in Amorphous Solid Dispersions on Drug Solubility, Miscibility, and Mobility.
Topics: Chlorpropamide; Drug Compounding; Halogens; Hydrogen Bonding; Polymers; Solubility; Tolbutamide | 2022 |
Analysis of Hypoglycemic Drugs by Liquid Chromatography-Tandem Mass Spectrometry.
Topics: Chlorpropamide; Chromatography, High Pressure Liquid; Chromatography, Liquid; Glipizide; Glyburide; Humans; Hypoglycemic Agents; Nateglinide; Pioglitazone; Rosiglitazone; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tolazamide; Tolbutamide | 2024 |