Compounds > chlorpropamide

chlorpropamide and phenobarbital

chlorpropamide has been researched along with phenobarbital in 17 studies

Research

Studies (17)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (35.29)	18.7374
1990's	0 (0.00)	18.2507
2000's	5 (29.41)	29.6817
2010's	6 (35.29)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Lombardo, F; Obach, RS; Waters, NJ	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bending, MR; Dollery, CT; Kahn, GC; Mucklow, JC	1
Jatlow, P	1
De Matteis, F	2
Aggarwal, V; Sunshine, I	1
Arranto, AJ; Keinänen, K; Kerola, T; Saarni, HU; Sotaniemi, EA; Stengård, JH; Sutinen, S	1

Reviews

3 review(s) available for chlorpropamide and phenobarbital

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Toxic hepatic porphyrias. Seminars in hematology, 1968, Volume: 5, Issue:4 Topics: Alcoholism; Antifungal Agents; Chemical and Drug Induced Liver Injury; Chlorpropamide; Hexachlorocyclohexane; Humans; Liver; Phenobarbital; Phenytoin; Porphyrias; Sulfanilamides; Sulfones; Tolbutamide; Turkey	1968
Disturbances of liver porphyrin metabolism caused by drugs. Pharmacological reviews, 1967, Volume: 19, Issue:4 Topics: Animals; Chlorpropamide; Drug-Related Side Effects and Adverse Reactions; Estrogens; Griseofulvin; Humans; Hypnotics and Sedatives; Liver; Mice; Phenobarbital; Porphyrias; Porphyrins; Rats; Sulfones; Tolbutamide	1967

Other Studies

14 other study(ies) available for chlorpropamide and phenobarbital

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Drug concentration in saliva. Clinical pharmacology and therapeutics, 1978, Volume: 24, Issue:5 Topics: Adolescent; Adult; Aged; Antipyrine; Chlorpropamide; Humans; Hydrogen-Ion Concentration; Male; Meperidine; Middle Aged; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Propranolol; Protein Binding; Saliva; Tolbutamide	1978
Ultraviolet spectrophotometric analysis of barbiturates: evaluation of potential interferences. American journal of clinical pathology, 1973, Volume: 59, Issue:2 Topics: Acetaminophen; Barbiturates; Chlorothiazide; Chlorpropamide; Dicumarol; Humans; Methods; Nicotinic Acids; Oxyphenbutazone; Phenacetin; Phenindione; Phenobarbital; Phenylbutazone; Phenytoin; Salicylates; Spectrophotometry, Ultraviolet; Sulfamethoxazole; Sulfinpyrazone; Sulfisoxazole; Theobromine; Theophylline; Warfarin	1973
Determination of sulfonylureas and metabolites by pyrolysis gas chromatography. Clinical chemistry, 1974, Volume: 20, Issue:2 Topics: Amobarbital; Chlorobenzenes; Chlorpropamide; Chromatography, Gas; Evaluation Studies as Topic; Humans; Mass Spectrometry; Methods; Pentobarbital; Phenobarbital; Secobarbital; Structure-Activity Relationship; Sulfonamides; Sulfonylurea Compounds; Time Factors; Tolazamide; Tolbutamide	1974
Hepatic glucose-6-phosphatase activity in non-insulin dependent diabetics. Effect of enzyme-inducing drugs. Acta medica Scandinavica, 1984, Volume: 215, Issue:4 Topics: Aged; Antipyrine; Blood Glucose; Chlorpropamide; Diabetes Mellitus, Type 2; Enzyme Induction; Female; Glipizide; Glucose-6-Phosphatase; Humans; Liver; Liver Glycogen; Male; Medroxyprogesterone; Medroxyprogesterone Acetate; Microsomes, Liver; Middle Aged; Phenobarbital	1984