chlorpropamide and diazoxide

chlorpropamide has been researched along with diazoxide in 31 studies

Research

Studies (31)

Timeframe	Studies, this research(%)	All Research%
pre-1990	16 (51.61)	18.7374
1990's	0 (0.00)	18.2507
2000's	6 (19.35)	29.6817
2010's	9 (29.03)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Lombardo, F; Obach, RS; Waters, NJ	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Gozalbes, R; Pineda-Lucena, A	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Pfeifer, MA; Samols, E; Wolter, CF	1
Fiser, RH; Jacobs, RF; Kiel, EA; Nix, RA; Paulus, TE	1
Johnson, SF; Peake, GT; Schade, DS	1
Christensen, S	1
Yoshinaga, T	1
Conn, JW; Fajans, SS; Floyd, JC; Guntsche, EM; Knopf, RF; Rull, J	1
Conn, JW; Fajans, SS; Floyd, JC; Guntsche, EM; Knopf, RF; Rull, JA; Thiffault, CA	1
Ariëns, EJ	1
Miller, M; Moses, AM	1
Halmos, T; Radó, JP; Szende, L; Takó, J	1
Christensen, HN; Conn, JW; Fajans, SS; Floyd, JC; Pek, S; Quibrera, R	1
Borbély, L; Radó, JP; Szende, L; Takó, J	1
Gulbenkian, A; Ornstein, L; Tabachnick, II	1
Graham, EM; Jeffery, WH	1
Tintinalli, JE	1
LANGDON, RG; WOLFF, FW	1
Dreixler, JC; Hemmert, JW; Lee, HT; Rosenbaum, DM; Roth, S; Shaikh, AR; Shen, Y; Shenoy, SK	1

Reviews

3 review(s) available for chlorpropamide and diazoxide

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Oral antidiabetics. Dose, plasma concentration and effect]. Acta diabetologica latina, 1969, Volume: 6 Suppl 1 Topics: Acetohexamide; Adrenergic beta-Antagonists; Animals; Blood Glucose; Carbutamide; Chemical Phenomena; Chemistry; Chlorpropamide; Cyclic AMP; Diazoxide; Drug Antagonism; Drug Synergism; Glucagon; Glucose; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Isoproterenol; Kidney; Liver; Sulfonamides; Sulfonylurea Compounds; Theophylline; Tolbutamide	1969
Drug-induced dilutional hyponatremia. The New England journal of medicine, 1974, Dec-05, Volume: 291, Issue:23 Topics: Acetaminophen; Amitriptyline; Animals; Anura; Body Fluids; Carbamazepine; Chlorpropamide; Clofibrate; Cyclophosphamide; Diabetes Insipidus; Diabetes Mellitus; Diazoxide; Drug-Related Side Effects and Adverse Reactions; Humans; Hypoglycemic Agents; Hyponatremia; Kidney; Rats; Sodium; Sulfonylurea Compounds; Tolbutamide; Urinary Bladder; Vasopressins; Vincristine; Water Intoxication; Water-Electrolyte Balance	1974

Other Studies

28 other study(ies) available for chlorpropamide and diazoxide

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
QSAR-based solubility model for drug-like compounds. Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19 Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
Management of chlorpropamide-induced hypoglycemia with diazoxide. Southern medical journal, 1978, Volume: 71, Issue:5 Topics: Aged; Chlorpropamide; Diazoxide; Humans; Hypoglycemia; Male	1978
Intravenous infusion of diazoxide in the treatment of chlorpropamide-induced hypoglycemia. The Journal of pediatrics, 1978, Volume: 93, Issue:5 Topics: Child; Chlorpropamide; Diazoxide; Humans; Hypoglycemia; Infusions, Parenteral; Male	1978
Chlorpropamide-induced hypoglycemia: successful treatment with diazoxide. The American journal of medicine, 1977, Volume: 63, Issue:5 Topics: Adolescent; Chlorpropamide; Diazoxide; Glucagon; Glucose; Humans; Hypoglycemia; Insulin; Male	1977
Effect of antidiuretic drugs in rats with lithium-induced polyuria. Acta pharmacologica et toxicologica, 1976, Volume: 38, Issue:2 Topics: Animals; Bendroflumethiazide; Carbamazepine; Chlorpropamide; Diazoxide; Dose-Response Relationship, Drug; Lithium; Male; Polyuria; Rats	1976
[A morphological study on the mechanism of insulin-release, using sulfonylurea, l-leucine, and alpha-ketocarboxylic acids]. Nihon Naibunpi Gakkai zasshi, 1968, Oct-20, Volume: 44, Issue:7 Topics: Animals; Blood Glucose; Butyrates; Chlorpropamide; Diabetes Mellitus; Diazoxide; Ferredoxins; Histocytochemistry; Humans; Hypoglycemia; Hypoglycemic Agents; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Leucine; Methods; Rats; Staining and Labeling; Sulfur Isotopes; Time Factors; Zinc	1968
Benzothiadiazine suppression of insulin release from normal and abnormal islet tissue in man. The Journal of clinical investigation, 1966, Volume: 45, Issue:4 Topics: Adenoma, Islet Cell; Adult; Antihypertensive Agents; Blood Glucose; Chlorpropamide; Diazoxide; Humans; In Vitro Techniques; Insulin; Leucine; Male; Trichlormethiazide	1966
A difference in mechanism by which leucine and other amino acids induce insulin release. The Journal of clinical endocrinology and metabolism, 1967, Volume: 27, Issue:11 Topics: Adenoma, Islet Cell; Adult; Amino Acids; Arginine; Blood Glucose; Chlorpropamide; Diazoxide; Female; Humans; Insulin; Insulin Secretion; Leucine; Male; Valine	1967
Effects of intravenous diazoxide and chlorpropamide on renal function in man. American heart journal, 1973, Volume: 85, Issue:6 Topics: Chlorpropamide; Dehydration; Diabetes Insipidus; Diazoxide; Diuresis; Glomerular Filtration Rate; Humans; Hypertension; Hypertonic Solutions; Injections, Intravenous; Kidney; Osmolar Concentration; Potassium; Regional Blood Flow; Sodium; Sodium Chloride	1973
Stimulation of insulin release in the dog by a nonmetabollizable amino acid. Comparison with leucine and arginine. The Journal of clinical endocrinology and metabolism, 1971, Volume: 33, Issue:1 Topics: Amino Acids; Animals; Arginine; Bridged-Ring Compounds; Chlorpropamide; Diazoxide; Dogs; Female; Glucagon; Heptoses; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Stimulation, Chemical	1971
Clinical value and mode of action of chlorpropamide in diabetes insipidus. The American journal of the medical sciences, 1970, Volume: 260, Issue:6 Topics: Adolescent; Adult; Chlorpropamide; Diabetes Insipidus; Diazoxide; Drinking Behavior; Female; Humans; Hypoglycemia; Kidney Tubules; Long-Term Care; Male; Middle Aged; Nephritis, Interstitial; Polyuria; Psychophysiologic Disorders; Vasopressins	1970
The use of diazoxide inhibition of insulin secretion as a tool to investigate insulin stimulation by other agents. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1972, Volume: 4, Issue:2 Topics: Animals; Antigens; Chlorpropamide; Depression, Chemical; Diazoxide; Drug Antagonism; Immunoassay; Insulin; Insulin Secretion; Kinetics; Male; Mice; Mice, Inbred Strains; Stimulation, Chemical; Tolbutamide	1972
Treatment of chlorpropamide overdose with diazoxide. Drug intelligence & clinical pharmacy, 1983, Volume: 17, Issue:5 Topics: Adolescent; Chlorpropamide; Diazoxide; Humans; Hypoglycemia; Male	1983
Treatment of drug-induced hypoglycemia. Annals of emergency medicine, 1980, Volume: 9, Issue:4 Topics: Chlorpropamide; Diazoxide; Humans; Hypoglycemia	1980
CONJOINT CLINIC ON DRUGS AND DIABETES. Journal of chronic diseases, 1964, Volume: 17 Topics: Adrenalectomy; Antihypertensive Agents; Benzothiadiazines; Biomedical Research; Blood; Blood Glucose; Body Weight; Chlorothiazide; Chlorpropamide; Diabetes Mellitus; Diazoxide; Diuretics; Dogs; Hydrochlorothiazide; Hypertension; Hypophysectomy; Nitrogen; Pharmacology; Placebos; Polythiazide; Potassium; Rats; Research; Tolbutamide; Toxicology; Trichlormethiazide; Urea	1964
The role of Akt/protein kinase B subtypes in retinal ischemic preconditioning. Experimental eye research, 2009, Volume: 88, Issue:3 Topics: Androstadienes; Animals; Apoptosis; Blotting, Western; Chlorpropamide; Diazoxide; Dose-Response Relationship, Drug; Electroretinography; Ischemia; Ischemic Preconditioning; Isoenzymes; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Retinal Vessels; RNA, Small Interfering; Wortmannin	2009