chlorpromazine has been researched along with valproic acid in 48 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 7 (14.58) | 18.7374 |
1990's | 5 (10.42) | 18.2507 |
2000's | 19 (39.58) | 29.6817 |
2010's | 15 (31.25) | 24.3611 |
2020's | 2 (4.17) | 2.80 |
Authors | Studies |
---|---|
Andrews, PR; Craik, DJ; Martin, JL | 1 |
Strassburg, CP; Tukey, RH | 1 |
Topliss, JG; Yoshida, F | 1 |
Abraham, MH; Acree, WE; Ibrahim, A | 1 |
Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
Glen, RC; Lowe, R; Mitchell, JB | 1 |
Ekins, S; Williams, AJ; Xu, JJ | 1 |
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S | 1 |
Atzpodien, EA; Csato, M; Doessegger, L; Fischer, H; Lenz, B; Schmitt, G; Singer, T | 1 |
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
Wada, JA | 1 |
Raskin, NH | 1 |
Bovell, M; Chung, T; Leake, J; MacMillan, V | 1 |
Bach, N; Schaffner, F; Thung, SN; Tobias, H | 1 |
Samanin, R; Tullii, M; Vezzani, A; Wu, HQ | 1 |
Hanano, M; Iga, T; Sawada, Y; Sugiyama, Y | 1 |
Chiba, K; Iizuka, R; Ishizaki, T; Kobayashi, K; Saito, M | 1 |
Auchus, AP; Freeman, A; Green, RC | 1 |
Finnerty, M; Levin, Z; Miller, LJ | 1 |
Heick, A | 1 |
Hardy-Baylé, MC | 1 |
Agam, G; Belmaker, RH; Kozlovsky, N; Nadri, C | 1 |
Benabarre, A; Brugué, E; Colom, F; Daban, C; Goikolea, JM; Martínez-Arán, A; Reinares, M; Salamero, M; Sánchez-Moreno, J; Torrent, C; Vieta, E | 1 |
Girimaji, SC; Jairam, R; Seshadri, SP; Srinath, S | 1 |
Geddes, J | 2 |
Gupta, SB; Laghate, VD | 1 |
Awad, AG | 1 |
Brodaty, H; Cumming, R; Forrester, L; Grayson, D; Hollis, J; Touyz, S | 2 |
Andrieu, T; Casagrande, F; Clayette, P; Dormont, D; Legendre, C | 1 |
Feifel, D; Melendez, G; Shilling, PD | 1 |
Lubszky, S; Reinhart, WH; Schulzki, T; Thöny, S | 1 |
Abd-ElGawad, M; Abdelhay, HM; Abdelmonem, H; Abdelwadoud, GT; Ahmed, AE; Al-Dardery, NM; Alhosini, ANM; Kamel, MA; Mohamed, SW | 1 |
8 review(s) available for chlorpromazine and valproic acid
Article | Year |
---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Pharmacological prophylaxis in the kindling model of epilepsy.
Topics: Amygdala; Anesthetics, Local; Animals; Antidepressive Agents, Tricyclic; Atropine; Aziridines; Carbamazepine; Catecholamines; Cats; Cerebral Cortex; Chlorpromazine; Clorazepate Dipotassium; Diazepam; Disease Models, Animal; Drug Evaluation, Preclinical; Epilepsy; Haplorhini; Hydroxydopamines; Phenobarbital; Phenytoin; Rats; Reserpine; Seizures; Valproic Acid | 1977 |
Modern pharmacotherapy of migraine.
Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Chlorpromazine; Dihydroergotamine; Ergotamine; Humans; Migraine Disorders; Prochlorperazine; Valproic Acid | 1990 |
Prediction of the disposition of nine weakly acidic and six weakly basic drugs in humans from pharmacokinetic parameters in rats.
Topics: Animals; Antipyrine; Barbiturates; Biological Availability; Chlorpromazine; Diazepam; Drug Evaluation; Female; Half-Life; Humans; Kinetics; Male; Metabolic Clearance Rate; Pentazocine; Pharmaceutical Preparations; Phenylbutazone; Phenytoin; Propranolol; Quinidine; Rats; Species Specificity; Tissue Distribution; Tolbutamide; Valproic Acid; Warfarin | 1985 |
Bipolar disorder.
Topics: Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Chlorpromazine; Humans; Lithium; Psychotherapy; Valproic Acid | 2003 |
Bipolar disorder.
Topics: Antidepressive Agents; Antimanic Agents; Benzodiazepines; Bipolar Disorder; Chlorpromazine; Cognitive Behavioral Therapy; Humans; Lithium Carbonate; Olanzapine; Piperazines; Thiazoles; Valproic Acid | 2005 |
The efficacy and safety of metoclopramide in relieving acute migraine attacks compared with other anti-migraine drugs: a systematic review and network meta-analysis of randomized controlled trials.
Topics: Chlorpromazine; Granisetron; Headache; Humans; Ketorolac; Metoclopramide; Migraine Disorders; Nausea; Network Meta-Analysis; Prochlorperazine; Randomized Controlled Trials as Topic; Sumatriptan; Valproic Acid | 2023 |
1 trial(s) available for chlorpromazine and valproic acid
Article | Year |
---|---|
A prospective 4-5 year follow-up of juvenile onset bipolar disorder.
Topics: Adolescent; Adult; Age of Onset; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Chlorpromazine; Diagnostic and Statistical Manual of Mental Disorders; Drug Administration Schedule; Female; Follow-Up Studies; Haloperidol; Humans; Imipramine; Lithium Carbonate; Male; Phenotype; Prospective Studies; Recovery of Function; Risperidone; Secondary Prevention; Severity of Illness Index; Valproic Acid | 2004 |
39 other study(ies) available for chlorpromazine and valproic acid
Article | Year |
---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization | 2008 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors | 2012 |
In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets.
Topics: Animals; Cattle; Cells, Cultured; Computer Simulation; Cornea; Drug-Related Side Effects and Adverse Reactions; Fibroblasts; Lipidoses; Lysosomal Storage Diseases; Models, Molecular; Pharmaceutical Preparations; Phospholipids; Structure-Activity Relationship; Thermodynamics | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
The effect of valproic acid on the 5-hydroxyindoleacetic, homovanillic and lactic acid levels of cerebrospinal fluid.
Topics: Animals; Anticonvulsants; Brain; Chlorpromazine; Dose-Response Relationship, Drug; Homovanillic Acid; Hydroxyindoleacetic Acid; Lactates; Lactic Acid; Male; Probenecid; Rats; Rats, Inbred Strains; Valproic Acid | 1987 |
Exaggerated cholestasis and hepatic fibrosis following simultaneous administration of chlorpromazine and sodium valproate.
Topics: Chlorpromazine; Cholestasis; Drug Interactions; Hiccup; Humans; Liver Cirrhosis; Male; Middle Aged; Valproic Acid | 1989 |
Anticonvulsant drugs effective against human temporal lobe epilepsy prevent seizures but not neurotoxicity induced in rats by quinolinic acid: electroencephalographic, behavioral and histological assessments.
Topics: Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Chlorpromazine; Diazepam; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Male; Phenobarbital; Phenytoin; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Seizures; Valproic Acid | 1986 |
The effects of neuroleptics (haloperidol and chlorpromazine) on the pharmacokinetics of valproic acid in schizophrenic patients.
Topics: Adult; Antipsychotic Agents; Chlorpromazine; Drug Interactions; Electroencephalography; Female; Half-Life; Haloperidol; Humans; Kinetics; Male; Middle Aged; Schizophrenia; Valproic Acid | 1984 |
Agitated behavior relieved following treatment of cervical dystonia in dementia.
Topics: Alzheimer Disease; Botulinum Toxins; Chlorpromazine; Dystonia; Female; Humans; Isoxazoles; Middle Aged; Neck Muscles; Phenytoin; Piperidines; Risperidone; Valproic Acid | 1995 |
Acute manic episodes in pregnancy.
Topics: Adult; Bipolar Disorder; Chlorpromazine; Comorbidity; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Electroconvulsive Therapy; Female; Haloperidol; Humans; Lorazepam; Pregnancy; Pregnancy Complications; Valproic Acid | 1996 |
[Diabolic hiccup].
Topics: Baclofen; Brain Stem; Calcium Channel Blockers; Chlorpromazine; Dopamine Antagonists; GABA Agents; Hiccup; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Nifedipine; Time Factors; Valproic Acid | 1997 |
[Manic syndrome: diagnostic trends and principles of treatment].
Topics: Adult; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Chlorpromazine; Diagnosis, Differential; Haloperidol; Hospitalization; Humans; Iatrogenic Disease; Lithium; Neurocognitive Disorders; Schizophrenia; Syndrome; Time Factors; Valproic Acid | 1998 |
Lack of effect of mood stabilizers or neuroleptics on GSK-3 protein levels and GSK-3 activity.
Topics: Affect; Animals; Antimanic Agents; Antipsychotic Agents; Blotting, Western; Chlorpromazine; Clozapine; Frontal Lobe; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Haloperidol; Lithium; Rats; Rats, Sprague-Dawley; Valproic Acid | 2003 |
Cognitive impairment in euthymic bipolar patients: implications for clinical and functional outcome.
Topics: Adult; Anticonvulsants; Antipsychotic Agents; Chlorpromazine; Cognition Disorders; Dysthymic Disorder; Female; Humans; Lithium Carbonate; Male; Memory Disorders; Neuropsychological Tests; Valproic Acid; Verbal Learning | 2004 |
Acute pancreatitis and diabetic ketoacidosis in non-diabetic person while on treatment with sodium valproate, chlorpromazine and haloperidol.
Topics: Acute Disease; Adult; Antimanic Agents; Bipolar Disorder; Chlorpromazine; Diabetic Ketoacidosis; Diagnosis, Differential; Haloperidol; Humans; Male; Pancreatitis; Valproic Acid | 2004 |
The rational use of medications in acute psychotic presentations -- the case for less is more.
Topics: Adult; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clopenthixol; Humans; Male; Olanzapine; Psychotic Disorders; Valproic Acid | 2006 |
Risk of death associated with antipsychotic drug dispensing in residential aged care facilities.
Topics: Aged; Anticonvulsants; Antipsychotic Agents; Australia; Benzodiazepines; Carbamazepine; Cause of Death; Chlorpromazine; Comorbidity; Cross-Sectional Studies; Death, Sudden; Female; Haloperidol; Homes for the Aged; Humans; Male; Nursing Homes; Olanzapine; Risk; Valproic Acid; Veterans | 2007 |
Sodium valproate does not augment Prpsc in murine neuroblastoma cells.
Topics: Animals; Cell Line, Tumor; Chlorpromazine; Dopamine Antagonists; Enzyme Inhibitors; Gene Expression Regulation; Mice; Neuroblastoma; Prions; Scrapie; Time Factors; Valproic Acid | 2007 |
Antipsychotic medication dispensing and risk of death in veterans and war widows 65 years and older.
Topics: Age Factors; Aged; Aged, 80 and over; Anticonvulsants; Antipsychotic Agents; Australia; Benzodiazepines; Carbamazepine; Cause of Death; Chlorpromazine; Cohort Studies; Dementia; Female; Haloperidol; Humans; Male; Mortality; Olanzapine; Proportional Hazards Models; Retrospective Studies; Risk; Risk Factors; Survival Rate; Valproic Acid; Veterans; Widowhood | 2007 |
Further characterization of the predictive validity of the Brattleboro rat model for antipsychotic efficacy.
Topics: Animals; Antipsychotic Agents; Chlorpromazine; Diazepam; Disease Models, Animal; Female; Imipramine; Inhibition, Psychological; Male; Psychotropic Drugs; Rats; Rats, Brattleboro; Reflex, Startle; Schizophrenia; Valproic Acid | 2011 |
Interaction of injectable neurotropic drugs with the red cell membrane.
Topics: Central Nervous System Agents; Chlorpromazine; Citalopram; Clomipramine; Clonazepam; Diazepam; Erythrocytes; Humans; Injections; Levetiracetam; Microscopy, Electron, Scanning; Neurotransmitter Agents; Phenobarbital; Phenytoin; Piracetam; Valproic Acid | 2014 |