chlorpromazine has been researched along with tolbutamide in 48 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 22 (45.83) | 18.7374 |
1990's | 1 (2.08) | 18.2507 |
2000's | 8 (16.67) | 29.6817 |
2010's | 17 (35.42) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Topliss, JG; Yoshida, F | 1 |
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
Abraham, MH; Acree, WE; Ibrahim, A | 1 |
Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
Briand, X; Faller, B; Lázaro, E; Lowe, PJ | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Conradi, R; Lee, PH; Shanmugasundaram, V | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
Gozalbes, R; Pineda-Lucena, A | 1 |
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
Ekins, S; Williams, AJ; Xu, JJ | 1 |
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F | 1 |
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S | 1 |
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U | 1 |
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
El-Denshary, EE; Montague, W | 1 |
Moore, W; Popiela, H | 1 |
Hanano, M; Iga, T; Sawada, Y; Sugiyama, Y | 1 |
Hellman, B; Sehlin, J; Täljedal, IB | 1 |
Iyer, KS; Menon, A; Moideen, TK | 1 |
Wosilait, WD | 1 |
Mennear, JH; Miya, TS; Susten, AS | 1 |
Durno, D; Howie, JG; Petrie, JC | 1 |
Blank, H; Ison, A | 1 |
Kligman, AM; Willis, I | 1 |
Kocialski, AB; Malone, MH; Marozzi, FJ | 1 |
Walder, HR | 1 |
Calhoun, FJ; Schrogie, JJ; Tolson, WW | 1 |
Davis, CM; Ison, AE | 1 |
Buckle, RM; Guillebaud, J | 1 |
HASSELBLATT, A; SCHUSTER, R | 1 |
HASSELBLATT, A; HAUN, G | 1 |
FINEBERG, SK | 1 |
HUDEPOHL, M; LEDERBOGEN, K | 1 |
CANIVET, J | 1 |
GRAUPNER, K; WIEZOREK, WD | 1 |
LUEDTKE, E | 1 |
HUGULEY, CM | 1 |
2 review(s) available for chlorpromazine and tolbutamide
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Prediction of the disposition of nine weakly acidic and six weakly basic drugs in humans from pharmacokinetic parameters in rats.
Topics: Animals; Antipyrine; Barbiturates; Biological Availability; Chlorpromazine; Diazepam; Drug Evaluation; Female; Half-Life; Humans; Kinetics; Male; Metabolic Clearance Rate; Pentazocine; Pharmaceutical Preparations; Phenylbutazone; Phenytoin; Propranolol; Quinidine; Rats; Species Specificity; Tissue Distribution; Tolbutamide; Valproic Acid; Warfarin | 1985 |
46 other study(ies) available for chlorpromazine and tolbutamide
Article | Year |
---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization | 2008 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
New approach to measure protein binding based on a parallel artificial membrane assay and human serum albumin.
Topics: Humans; Kinetics; Membranes, Artificial; Permeability; Protein Binding; Serum Albumin | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay.
Topics: 1-Methyl-3-isobutylxanthine; Cell Line; Cell Membrane Permeability; Humans; Models, Biological; Quantitative Structure-Activity Relationship; Skin Absorption | 2010 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors | 2012 |
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Effects of drugs on glucose and tolbutamide-stimulated insulin release from isolated rat islets of Langerhans.
Topics: Animals; Chlorpromazine; Female; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Phenylbutazone; Rats; Salicylates; Stimulation, Chemical; Tolbutamide | 1976 |
Tolbutamide stimulates proliferation of pancreatic beta cells in culture.
Topics: Animals; Calcium; Cell Division; Cell Survival; Cells, Cultured; Chlorpromazine; Diltiazem; Dose-Response Relationship, Drug; Glucose; Islets of Langerhans; Rats; Tolbutamide | 1991 |
The pancreatic -cell recognition of insulin secretagogues. IV. Islet uptake of sulfonylureas.
Topics: Animals; Antimycin A; Carbon Isotopes; Chlorpromazine; Diazoxide; Glucose; Glyburide; In Vitro Techniques; Islets of Langerhans; Leucine; Male; Mice; Serum Albumin; Sulfur Isotopes; Tolbutamide | 1973 |
Interaction of tolbutamide with phenothiazines and diphenhydramine.
Topics: Adult; Animals; Antipsychotic Agents; Blood Glucose; Chlorpromazine; Chlorprothixene; Diphenhydramine; Drug Combinations; Humans; Insulin; Islets of Langerhans; Prochlorperazine; Rabbits; Tolbutamide | 1972 |
An analysis of the effect of hypoalbuminemia on the amount of free drug in plasma for drugs bound at two sets of sites.
Topics: Binding Sites; Carbenoxolone; Chlorpromazine; Chlorpropamide; Computers; Dose-Response Relationship, Drug; Humans; Iopanoic Acid; Pharmaceutical Preparations; Phenylbutazone; Protein Binding; Quinidine; Salicylates; Serum Albumin; Sulfadiazine; Tolbutamide | 1974 |
Effect of chlorpromazine on glucose and tolbutamide-stimulated insulin release in the adrenalectomized rat.
Topics: Adrenal Glands; Adrenalectomy; Animals; Antigens; Blood Glucose; Chlorpromazine; Drug Interactions; Glucose; Hypoglycemia; Insulin; Insulin Antibodies; Insulin Secretion; Iodine Isotopes; Male; Rats; Time Factors; Tolbutamide | 1973 |
Awareness and experience of general practitioners of selected drug interactions.
Topics: Amitriptyline; Antidepressive Agents; Chlorpromazine; Cognition; Dibenzazepines; Drug Interactions; Family Practice; Humans; Hypnotics and Sedatives; Imipramine; Insulin; Monoamine Oxidase Inhibitors; Physicians; Public Opinion; Scotland; Sulfonamides; Surveys and Questionnaires; Tolbutamide; Warfarin | 1974 |
Testing drug phototoxicity in mice.
Topics: Anilides; Animals; Chlorothiazide; Chlorpromazine; Chlortetracycline; Demeclocycline; Methoxsalen; Mice; Phenothiazines; Photosensitivity Disorders; Prochlorperazine; Quinolines; Radiation Effects; Skin; Sunlight; Tetracycline; Tolbutamide; Ultraviolet Rays | 1967 |
Diagnosis of photosensitization reactions by the Scotch Tape provocative patch test.
Topics: Adult; Anilides; Chlorpromazine; Demeclocycline; Griseofulvin; Hexachlorophene; Humans; Male; Methods; Photosensitivity Disorders; Skin Tests; Sulfisoxazole; Tolbutamide | 1968 |
Effects of certain nonsteroid anti-inflammatory drugs, tolbutamide, and tetrahydroalstonine on blood glucose and carrageen in-induced pedal edema in rats.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Blood Glucose; Carrageenan; Chlorpromazine; Diabetes Mellitus, Experimental; Edema; Foot; Indoles; Indomethacin; Male; Phenylbutazone; Plant Extracts; Plethysmography; Protamines; Quinolizines; Rats; Rats, Inbred Strains; Secologanin Tryptamine Alkaloids; Semicarbazides; Tetrabenazine; Tolbutamide; Zinc | 1972 |
[Idiopathic and drug-induced acquired aplastic anemia. 2].
Topics: Adult; Anemia, Aplastic; Aspirin; Bone Marrow Examination; Chloramphenicol; Chlorpheniramine; Chlorpromazine; Gold; Hemoglobins; Humans; Hydantoins; Middle Aged; Penicillins; Phenacetin; Prognosis; Sulfisoxazole; Switzerland; Tetracycline; Tolbutamide | 1970 |
Effects of various drugs on the uterotropic response to mestranol and norethynodrel in the rat.
Topics: Aminosalicylic Acids; Animals; Chlorpromazine; Drug Synergism; Female; Imipramine; Mestranol; Norethynodrel; Organ Size; Phenobarbital; Phenylbutazone; Phenytoin; Proadifen; Rats; Scopolamine; Tolbutamide; Uterus | 1971 |
Phototoxicity of quinoline methanols and other drugs in mice and yeast.
Topics: Anilides; Animals; Chemical Phenomena; Chemistry; Chlordiazepoxide; Chlorothiazide; Chlorpromazine; Chlortetracycline; Griseofulvin; Methanol; Methoxsalen; Mice; Photosensitivity Disorders; Prochlorperazine; Quinolines; Tetracycline; Tolbutamide; Ultraviolet Rays; Yeasts | 1969 |
Hypoglycaemic coma occurring during treatment with chlorpromazine and orphenadrine.
Topics: Blood Glucose; Chlorpromazine; Coma; Female; Humans; Hypoglycemia; Mental Disorders; Middle Aged; Orphenadrine; Tolbutamide | 1967 |
[Effects of megaphen and veronal on rastinon hypoglycemia].
Topics: Barbital; Barbiturates; Chlorpromazine; Hypoglycemia; Hypoglycemic Agents; Pancreatic Diseases; Tolbutamide | 1958 |
[The significance of the sympathetic innervation of the liver for the inhibitory effects of chlorpromazine (Megaphen) and veronal on rastinon hypoglycemia].
Topics: Barbital; Barbiturates; Chlorpromazine; Hypoglycemia; Liver; Pancreatic Diseases; Tolbutamide | 1960 |
Clinical experience with chlorpropamide and comparative evaluation with tolbutamide.
Topics: Chlorpromazine; Chlorpropamide; Humans; Tolbutamide | 1960 |
[Inhibition of the hypoglycemic effect of rastinon by megaphen and its elimination by pendiomide].
Topics: Biological Transport; Bis-Trimethylammonium Compounds; Chlorpromazine; Hypoglycemia; Hypoglycemic Agents; Pancreatic Diseases; Tolbutamide | 1963 |
[Oral medication of diabetes mellitus].
Topics: Carbutamide; Chlorpromazine; Diabetes Mellitus; Humans; Hypoglycemic Agents; Sulfonylurea Compounds; Tolbutamide | 1962 |
[THE INFLUENCE OF THE CONSTITUENTS OF THE LYTIC COCKTAIL ON THE ACTION OF HYPOGLYCEMIC AGENTS].
Topics: Alcoholic Beverages; Cardiovascular Agents; Chlorpromazine; Ergot Alkaloids; Guinea Pigs; Hypoglycemic Agents; Insulin; Meperidine; Metformin; Oxytocics; Pharmacology; Phenformin; Promethazine; Research; Tolbutamide | 1963 |
[ON THE CONTROL OF RASTINON LOAD IN DIABETICS BY CHLOPROMAZINE].
Topics: Chlorpromazine; Diabetes Mellitus; Humans; Tolbutamide | 1963 |
DRUG-INDUCED BLOOD DYSCRASIAS. II. AGRANULOCYTOSIS.
Topics: Agranulocytosis; Analgesics; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Antipyretics; Antithyroid Agents; Chloramphenicol; Chlorpromazine; Diagnosis; Drug Therapy; Humans; Phenindione; Phenothiazines; Tolbutamide; Toxicology | 1964 |