chlorpromazine and taurocholic acid

chlorpromazine has been researched along with taurocholic acid in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19909 (52.94)18.7374
1990's3 (17.65)18.2507
2000's1 (5.88)29.6817
2010's4 (23.53)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Carey, MC; Ros, E; Small, DM1
Boyer, JL; Hruban, Z; Reed, JS; Tavoloni, N1
Carey, MC; Hirom, PC; Small, DM1
Kunze, H; Traynor, JR1
Hanano, M; Iga, T; Okudaira, K; Sawada, Y; Sugiyama, Y; Yamazaki, M1
Abernathy, CO; Gillespie, J; Tripodi, MF; Utili, R; Zimmerman, HJ1
Akerboom, T; Schneider, I; Sies, H; vom Dahl, S1
Scharschmidt, BF; Van Dyke, RW1
Hall, T; Hart, JR; Willson, RA1
Stacey, NH1
Hanano, M; Iga, T; Iwatsubo, T; Miyamoto, Y; Sugiyama, Y; Yuasa, H1
Boyer, JL; Reed, JS; Tavoloni, N1
Abdel-Razzak, Z; Anthérieu, S; Bachour-El Azzi, P; Dumont, J; Fromenty, B; Guguen-Guillouzo, C; Guillouzo, A; Robin, MA1
Abdel-Razzak, Z; Al-Attrache, H; Antherieu, S; Bachour-El Azzi, P; Guguen-Guillouzo, C; Guillouzo, A; Labbe, G; Lepage, S; Morel, I; Savary, CC; Sharanek, A1

Other Studies

17 other study(ies) available for chlorpromazine and taurocholic acid

ArticleYear
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Effects of chlorpromazine hydrochloride on bile salt synthesis, bile formation and biliary lipid secretion in the rhesus monkey: a model for chlorpromazine-induced cholestasis.
    European journal of clinical investigation, 1979, Volume: 9, Issue:1

    Topics: Animals; Bile; Bile Acids and Salts; Chlorpromazine; Cholestasis; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Lipid Metabolism; Macaca mulatta; Taurocholic Acid

1979
Effect of chlorpromazine on hepatic perfusion and bile secretory function in the isolated perfused rat liver.
    The Journal of laboratory and clinical medicine, 1979, Volume: 94, Issue:5

    Topics: Adenosine Triphosphatases; Animals; Bile; Cell Membrane; Chlorpromazine; In Vitro Techniques; Liver; Magnesium; Male; Nucleotidases; Perfusion; Rats; Sodium-Potassium-Exchanging ATPase; Taurocholic Acid

1979
A study of the physicochemical interactions between biliary lipids and chlorpromazine hydrochloride. Bile-salt precipitation as a mechanism of phenothiazine-induced bile secretory failure.
    The Biochemical journal, 1976, Mar-01, Volume: 153, Issue:3

    Topics: Animals; Bile; Bile Acids and Salts; Chemical Phenomena; Chemical Precipitation; Chemistry; Chlorpromazine; Female; Haplorhini; In Vitro Techniques; Lipids; Macaca mulatta; Nephelometry and Turbidimetry; Potentiometry; Sodium Dodecyl Sulfate; Taurocholic Acid; X-Ray Diffraction

1976
Inhibition of rat liver cholesterol esterase by local anaesthetics.
    Biochimica et biophysica acta, 1975, Oct-21, Volume: 409, Issue:1

    Topics: Anesthetics, Local; Animals; Carboxylic Ester Hydrolases; Chlorpromazine; Cholesterol; Deoxycholic Acid; Dibucaine; Dose-Response Relationship, Drug; Female; Kinetics; Liver; Oleic Acids; Polyethylene Glycols; Rats; Sterol Esterase; Taurocholic Acid; Tetracaine

1975
Correlation between the inhibitory effects of basic drugs on the uptake of cardiac glycosides and taurocholate by isolated rat hepatocytes.
    Pharmaceutical research, 1992, Volume: 9, Issue:9

    Topics: Animals; Chlorpromazine; Dipyridamole; Disopyramide; Drug Interactions; In Vitro Techniques; Lidocaine; Liver; Male; Nifedipine; Ouabain; Propranolol; Quinidine; Rats; Rats, Wistar; Sodium; Taurocholic Acid; Verapamil

1992
Effects of bile salt infusion on chlorpromazine-induced cholestasis in the isolated perfused rat liver.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1992, Volume: 199, Issue:1

    Topics: Animals; Bile; Chlorpromazine; Cholestasis; In Vitro Techniques; Isomerism; Kinetics; Liver; Male; Perfusion; Rats; Rats, Inbred Strains; Taurochenodeoxycholic Acid; Taurocholic Acid; Time Factors

1992
Cholestasis and changes of portal pressure caused by chlorpromazine in the perfused rat liver.
    Hepatology (Baltimore, Md.), 1991, Volume: 13, Issue:2

    Topics: Animals; Bile; Blood Pressure; Chlorpromazine; Cholestasis; Cyclooxygenase Inhibitors; Indomethacin; L-Lactate Dehydrogenase; Liver; Male; Oxygen Consumption; Perfusion; Portal System; Prostaglandin D2; Rats; Rats, Inbred Strains; Taurocholic Acid

1991
Effects of chlorpromazine on Na+-K+-ATPase pumping and solute transport in rat hepatocytes.
    The American journal of physiology, 1987, Volume: 253, Issue:5 Pt 1

    Topics: Alanine; Animals; Bile Acids and Salts; Biological Transport; Cells, Cultured; Chlorides; Chlorpromazine; Ion Channels; Kinetics; Liver; Ouabain; Rats; Rubidium Radioisotopes; Sodium; Sodium Radioisotopes; Sodium-Potassium-Exchanging ATPase; Taurocholic Acid

1987
Chlorpromazine, administered in vivo and in vitro, inhibits the efflux of bile acids in freshly isolated rat hepatocytes.
    Pharmacology & toxicology, 1989, Volume: 64, Issue:5

    Topics: Animals; Bile Acids and Salts; Chlorpromazine; Cholic Acid; Cholic Acids; Chromatography, Thin Layer; Glycocholic Acid; In Vitro Techniques; Liver; Male; Rats; Rats, Inbred Strains; Taurocholic Acid; Time Factors

1989
Effects of chlorpromazine on taurocholate transport in isolated rat hepatocytes.
    Biochemical pharmacology, 1988, Nov-01, Volume: 37, Issue:21

    Topics: Animals; Cells, Cultured; Chlorpromazine; Kinetics; Liver; Rats; Rats, Inbred Strains; Taurocholic Acid

1988
Effects of potential damaging agents on the microclimate-pH in the rat jejunum.
    Journal of pharmaceutical sciences, 1986, Volume: 75, Issue:12

    Topics: Acetazolamide; Acetylcysteine; Amiloride; Animals; Aspirin; Chlorpromazine; Glucose; In Vitro Techniques; Intestinal Mucosa; Jejunum; Ouabain; Rats; Rats, Inbred Strains; Taurocholic Acid

1986
Effect of chlorpromazine on hepatic clearance and excretion of bile acids by the isolated perfused rat liver.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1982, Volume: 170, Issue:4

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bile Acids and Salts; Chlorpromazine; Liver; Liver Circulation; Male; Rats; Rats, Inbred Strains; Taurocholic Acid

1982
Oxidative stress plays a major role in chlorpromazine-induced cholestasis in human HepaRG cells.
    Hepatology (Baltimore, Md.), 2013, Volume: 57, Issue:4

    Topics: Actins; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Carcinoma, Hepatocellular; Cell Line, Tumor; Chlorpromazine; Cholestasis; Humans; In Vitro Techniques; Liver Neoplasms; Membrane Potential, Mitochondrial; Oxidative Stress; Reactive Oxygen Species; Taurocholic Acid

2013
Impact of inflammation on chlorpromazine-induced cytotoxicity and cholestatic features in HepaRG cells.
    Drug metabolism and disposition: the biological fate of chemicals, 2014, Volume: 42, Issue:9

    Topics: Actins; Bile Acids and Salts; C-Reactive Protein; Cell Line; Chlorpromazine; Cholestasis; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Down-Regulation; Humans; Inflammation; Interleukins; Organic Anion Transporters, Sodium-Dependent; Oxidative Stress; RNA, Messenger; Symporters; Taurocholic Acid

2014