chlorpromazine has been researched along with spiperone in 60 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (63.33) | 18.7374 |
| 1990's | 14 (23.33) | 18.2507 |
| 2000's | 5 (8.33) | 29.6817 |
| 2010's | 3 (5.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| George, SR; Guan, HC; Laurier, LG; Ng, G; Niznik, HB; O'Dowd, BF; Seeman, P; Sunahara, RK; Torchia, J; Van Tol, HH | 1 |
| Bouthenet, ML; Giros, B; Martres, MP; Schwartz, JC; Sokoloff, P | 1 |
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Choudhary, MS; Craigo, SC; Meltzer, HY; Monsma, FJ; Roth, BL; Shen, Y; Sibley, DR; Uluer, A | 1 |
| Amlaiky, N; Hen, R; Plassat, JL | 1 |
| Egan, CT; Herrick-Davis, K; Teitler, M | 1 |
| Audinot, V; Chaput, C; Conte, C; Gavaudan, S; Millan, MJ; Newman-Tancredi, A; Touzard, M; Verrièle, L | 1 |
| Grinde, E; Herrick-Davis, K; Teitler, M | 1 |
| Glennon, RA | 1 |
| Fang, X; Hu, Z; Levant, B; Min, J; Varady, J; Wang, S; Wu, X | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Dismukes, K; Mulder, AH | 1 |
| Cross, AJ; Owen, F; Poulter, M; Waddington, JL | 1 |
| Gaillard, JM; Kafi, S | 1 |
| Coupet, J; Rauh, CE | 1 |
| Meltzer, HY; So, R | 1 |
| Fang, VS; Goode, DJ; Meltzer, HY; Schyve, PM; Young, M | 1 |
| Czlonkowski, A; Herz, A; Höllt, V | 1 |
| Carlson, KR; Eibergen, RD | 2 |
| Hara, H; Ikegami, A; Ito, K; Ozaki, A; Sukamoto, T; Yamashita, A | 1 |
| Greenshaw, AJ; Juorio, AV; Paterson, IA; Zhu, MY | 1 |
| Ben-Shachar, D; Pinhassi, B; Youdim, MB | 1 |
| Patterson, TA; Schenk, JO | 1 |
| Kobayashi, T; Shimizu, H; Toru, M | 1 |
| Convents, A; De Backer, JP; De Keyser, J; Ebinger, G; Vauquelin, G | 1 |
| Rao, ML | 1 |
| Madras, BK; Seeman, P | 1 |
| Barrantes, MA; Blosser, JC; Manian, AA; McCreedy, SA; Palmer, GC | 1 |
| Andree, TH; Koenig, JI; Meltzer, HY; Mikuni, M; Tong, CY | 1 |
| Hayashi, T; Kunihara, M; Tadokoro, S | 1 |
| Barone, D; Peruzzi, M; Pugnetti, P; Restelli, A | 1 |
| Andorn, AC | 1 |
| Krska, J; Sampath, G; Shah, A; Soni, SD | 1 |
| Harada, T; Otsuki, S; Sato, M | 1 |
| Suzuki, S; Yamazaki, M | 1 |
| Hong, M; Jenner, P; Kilpatrick, GJ; Marsden, CD | 1 |
| Aghajanian, GK; Rasmussen, K | 1 |
| Arnett, CD; Barouche, F; Brodie, JD; Fowler, JS; MacGregor, RR; Russell, JA; Shiue, CY; Smith, M; Wolf, AP; Wolkin, A | 1 |
| Randall, PK; Yurek, DM | 1 |
| Speiser, Z; Weinstock, M | 1 |
| Everitt, BJ; Fuxe, K; Hökfelt, T | 1 |
| Hirano, M; Kim, JS; Kojima, M; Matsumoto, T; Nakahara, T; Uchimura, H | 1 |
| Dominy, BW; Koch, SW; Koe, BK | 1 |
| Chiu, S; Mishra, RK; Paulose, CS | 1 |
| Kostowski, W; Płaźnik, A | 1 |
| Angeby, K; Florvall, L; Hall, H; Köhler, C; Lindbom, LO; Magnusson, O; Ogren, SO | 1 |
| Ho, BT; Peck, EJ; Schoolar, JC; Wan, CW | 1 |
| Marshall, AM; Mishra, RK; Ramwani, J | 1 |
| Zapata, P; Zuazo, A | 1 |
| Burke, RE; Fahn, S; Smeal, M; Wagner, HR | 1 |
| Angeby, T; Haglund, L; Köhler, C; Ogren, SO | 1 |
| Farooqui, T; Markovich, K; Miller, D; Uretsky, N; Wallace, L | 1 |
| Horikawa, T; Ito, A; Nomura, Y; Okada, F; Tokumitsu, Y | 1 |
| Bradley, RJ; Dwyer, DS; Liu, Y | 1 |
| Fu, D; Javitch, JA; Lin, H; Strange, PG; Wilson, J | 1 |
| Cochrane, DE; Li, W; Pechenik, JA | 1 |
| Johnson, MS; Laurila, JM; Ruuskanen, JO; Scheinin, M; Wissel, G; Xhaard, H | 1 |
| Allen, JM; Cohen, RW; Van Kummer, BH | 1 |
1 review(s) available for chlorpromazine and spiperone
| Article | Year |
|---|---|
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists | 2003 |
59 other study(ies) available for chlorpromazine and spiperone
| Article | Year |
|---|---|
Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Blotting, Northern; Brain; Cell Line; Cell Membrane; Cloning, Molecular; Dopamine; Humans; Kinetics; Molecular Sequence Data; Molecular Weight; Oligonucleotide Probes; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D5; RNA, Messenger; Sequence Homology, Nucleic Acid; Transfection | 1991 |
Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics.
Topics: Amino Acid Sequence; Animals; Antipsychotic Agents; Base Sequence; Brain Chemistry; Cell Line; Cloning, Molecular; Cricetinae; DNA; DNA Restriction Enzymes; Dopamine; Guanylyl Imidodiphosphate; Molecular Sequence Data; Nucleic Acid Hybridization; Polymerase Chain Reaction; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; RNA, Messenger; Sequence Homology, Nucleic Acid; Tissue Distribution | 1990 |
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors.
Topics: Animals; Antipsychotic Agents; Cell Line; Molecular Structure; Rats; Receptors, Serotonin | 1994 |
Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Brain; Cloning, Molecular; Cyclic AMP; DNA; Drosophila; Enzyme Activation; Humans; Intestinal Mucosa; Mice; Molecular Sequence Data; Myocardium; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists | 1993 |
Creation of a constitutively activated state of the 5-hydroxytryptamine2A receptor by site-directed mutagenesis: inverse agonist activity of antipsychotic drugs.
Topics: Animals; Antipsychotic Agents; COS Cells; Mutagenesis, Site-Directed; Phosphatidylinositols; Protein Conformation; Rats; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Structure-Activity Relationship | 1998 |
Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35S]GTPgammaS binding study.
Topics: Animals; Antipsychotic Agents; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Sulfur Radioisotopes | 1998 |
Inverse agonist activity of atypical antipsychotic drugs at human 5-hydroxytryptamine2C receptors.
Topics: Animals; Antipsychotic Agents; COS Cells; Dose-Response Relationship, Drug; Humans; Inositol Phosphates; Radioligand Assay; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Receptor Agonists | 2000 |
Molecular modeling of the three-dimensional structure of dopamine 3 (D3) subtype receptor: discovery of novel and potent D3 ligands through a hybrid pharmacophore- and structure-based database searching approach.
Topics: Algorithms; Binding Sites; Computational Biology; Crystallography, X-Ray; Databases, Protein; Humans; Kinetics; Ligands; Lipid Bilayers; Models, Molecular; Molecular Conformation; Mutation; Receptors, Dopamine D2; Receptors, Dopamine D3; Reproducibility of Results; Solvents; Structure-Activity Relationship; Tetrahydronaphthalenes; Water | 2003 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Effects of neuroleptics on release of 3H-dopamine from slices of rat corpus striatum.
Topics: Animals; Antipsychotic Agents; Apomorphine; Chlorpromazine; Cocaine; Corpus Striatum; Dopamine; Electric Stimulation; Fluphenazine; Haloperidol; Male; Rats; Spiperone | 1977 |
Change in the charactertistics of 3H-spiperone binding to rat striatal membranes after acute chlorpromazine administration: effects of buffer washing of membranes.
Topics: Animals; Antipsychotic Agents; Butyrophenones; Chlorpromazine; Corpus Striatum; Histological Techniques; Humans; Injections, Intraperitoneal; Male; Membranes; Rats; Receptors, Drug; Schizophrenia; Spiperone; Tromethamine | 1979 |
Brain dopamine receptors and sleep in the rat: effects of stimulation and blockade.
Topics: Animals; Apomorphine; Brain; Chlorpromazine; Dopamine; Electroencephalography; Electromyography; Male; Rats; Receptors, Drug; Sleep; Sleep, REM; Spiperone; Time Factors | 1976 |
3H-Spiroperidol binding to dopamine receptors in rat striatal membranes: influence of loxapine and its hydroxylated metabolites.
Topics: Animals; Butyrophenones; Chlorpromazine; Clozapine; Corpus Striatum; Dibenzoxazepines; Haloperidol; Hydroxylation; In Vitro Techniques; Loxapine; Membranes; Rats; Receptors, Dopamine; Spiperone | 1979 |
Effect of morphine, beta-endorphin and leu-enkephalin on 3H-spiroperidol binding to bovine pituitary membranes.
Topics: Animals; Binding Sites; Butaclamol; Butyrophenones; Cattle; Chlorpromazine; Dose-Response Relationship, Drug; Endorphins; Enkephalins; Haloperidol; Membranes; Morphine; Pituitary Gland, Anterior; Spiperone | 1979 |
Effect of clozapine on human serum prolactin levels.
Topics: Animals; Binding, Competitive; Chlorpromazine; Clozapine; Dibenzazepines; Female; Humans; Male; Prolactin; Rats; Receptors, Dopamine; Schizophrenia; Spiperone; Time Factors | 1979 |
The demonstration in vivo of specific binding sites for neuroleptic drugs in mouse brain.
Topics: Animals; Apomorphine; Brain; Catalepsy; Chlorpromazine; Dibenzocycloheptenes; Dopamine; Haloperidol; Humans; Male; Mice; Piribedil; Quinolizines; Receptors, Dopamine; Receptors, Drug; Spiperone; Structure-Activity Relationship; Tranquilizing Agents | 1977 |
Dyskinesias in monkeys: interaction of methamphetamine with prior methadone treatment.
Topics: Animals; Chlorpromazine; Clozapine; Diazepam; Dyskinesia, Drug-Induced; Haloperidol; Haplorhini; Humans; Macaca mulatta; Male; Methadone; Methamphetamine; Naloxone; Phenobarbital; Phentolamine; Physostigmine; Spiperone; Stereotyped Behavior | 1976 |
Susceptibility to amphetamine-elicited dyskinesias following chronic methadone treatment in monkeys.
Topics: Animals; Chlorpromazine; Clozapine; Diazepam; Drug Interactions; Dyskinesia, Drug-Induced; Haloperidol; Haplorhini; Macaca mulatta; Male; Methadone; Methamphetamine; Phenobarbital; Phentolamine; Physostigmine; Spiperone; Time Factors | 1976 |
Neurochemical investigation on the effects of a new diphenylpiperazine calcium antagonist, KB-2796, on the central dopaminergic system of rats.
Topics: Animals; Calcium Channel Blockers; Chlorpromazine; Corpus Striatum; Dopamine; Flunarizine; In Vitro Techniques; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Tritium | 1992 |
The effects of some neuroleptics and d-amphetamine on striatal 2-phenylethylamine in the mouse.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; Chlorpromazine; Corpus Striatum; Dextroamphetamine; Dopamine; Fluphenazine; Homovanillic Acid; In Vitro Techniques; Male; Mice; Monoamine Oxidase Inhibitors; Pargyline; Phenethylamines; Selegiline; Spiperone; Synaptic Transmission | 1991 |
Prevention of neuroleptic-induced dopamine D2 receptor supersensitivity by chronic iron salt treatment.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; Apomorphine; Brain Chemistry; Chlorpromazine; Chromatography, High Pressure Liquid; Dopamine; Ferrous Compounds; Free Radicals; Hemoglobins; Homovanillic Acid; In Vitro Techniques; Iron; Liver; Male; Nerve Degeneration; Prolactin; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone | 1991 |
Effects of acute and chronic systemic administration of some typical antipsychotic drugs on turnover of dopamine and potassium ion-induced release of dopamine in the striatum of the rat in vivo.
Topics: Animals; Biotransformation; Chlorpromazine; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Haloperidol; Male; Potassium; Rats; Rats, Inbred Strains; Spiperone | 1991 |
[The inhibition of dopamine D1 and D2 receptors in human putamen by antipsychotic drugs].
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Benzamides; Benzazepines; Chlorpromazine; Depression, Chemical; Female; Haloperidol; Humans; In Vitro Techniques; Putamen; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Spiperone; Sulpiride | 1990 |
D2 dopamine receptors in calf globus pallidus: agonist high- and low-affinity sites not regulated by guanine nucleotide.
Topics: Animals; Butaclamol; Cattle; Chlorpromazine; Corpus Striatum; Domperidone; Dopamine; Globus Pallidus; Guanosine Triphosphate; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone | 1985 |
Monitoring of serum bioactivity levels of perazine and its metabolites by radioreceptor assay.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Binding, Competitive; Chlorpromazine; Female; Humans; Male; Middle Aged; Monitoring, Physiologic; Perazine; Radioligand Assay; Receptors, Dopamine; Spiperone | 1989 |
Drug potencies on partially purified brain D2 dopamine receptors.
Topics: Animals; Butaclamol; Chlorpromazine; Corpus Striatum; Dogs; Fluphenazine; Haloperidol; Isoelectric Focusing; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone; Stereoisomerism; Time Factors | 1985 |
Correlation of activity of chlorpromazine and respective hydroxy, dimethoxy and sulphoxide analogues on dopamine, muscarinic, histamine and calmodulin sites of action.
Topics: Adenylyl Cyclase Inhibitors; Animals; Binding Sites; Calmodulin; Cerebral Cortex; Chlorpromazine; Cyclic AMP; Dopamine; Histamine; Hypothalamus; Phosphoric Diester Hydrolases; Pirenzepine; Rats; Receptors, Dopamine; Receptors, Muscarinic; Spiperone; Sulfoxides | 1988 |
Differential effect of subchronic treatment with various neuroleptic agents on serotonin2 receptors in rat cerebral cortex.
Topics: 5,7-Dihydroxytryptamine; Animals; Antipsychotic Agents; Cerebral Cortex; Chlorpromazine; Clozapine; Female; Haloperidol; Imipramine; Ketanserin; Loxapine; Male; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Spiperone; Sulpiride | 1986 |
Changes in 3H-spiperone, 3H-WB 4101 and 3H-dihydroalprenolol bindings to brain membranes produced by postnatal pretreatment with chlorpromazine in adult rats.
Topics: Adrenergic alpha-Antagonists; Alprenolol; Animals; Animals, Newborn; Brain; Butyrophenones; Chlorpromazine; Dihydroalprenolol; Dioxanes; Dioxins; Female; Kinetics; Male; Membranes; Rats; Rats, Inbred Strains; Spiperone | 1985 |
Zetidoline, a specific dopamine antagonist devoid of antiserotonergic activity in rodent brain.
Topics: 5-Hydroxytryptophan; Animals; Antipsychotic Agents; Binding, Competitive; Brain; Chlorpromazine; Dopamine Antagonists; Haloperidol; Imidazoles; In Vitro Techniques; Male; Mice; Rats; Rats, Inbred Strains; Reflex; Seizures; Serotonin; Serotonin Antagonists; Spiperone; Synaptic Membranes | 1985 |
Do antipsychotic drugs and serotonin down regulate [3H]-spiroperidol binding sites in human cortex?
Topics: Adolescent; Adult; Antipsychotic Agents; Binding Sites; Butyrophenones; Cerebral Cortex; Chlorpromazine; Haloperidol; Humans; Kinetics; Middle Aged; Prazosin; Serotonin; Spiperone | 1986 |
Radio receptor assay of serum neuroleptic levels in psychiatric patients.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Chlorpromazine; Dose-Response Relationship, Drug; Haloperidol; Humans; Radioligand Assay; Receptors, Dopamine; Schizophrenia; Spiperone | 1986 |
Neuroleptic drugs and 5HT1 receptor: different potencies of various neuroleptic drugs on 5HT1 receptors in discrete regions of the rat brain.
Topics: Animals; Antipsychotic Agents; Brain; Chlorpromazine; Dibenzothiepins; Haloperidol; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiperone | 1985 |
Toxicology of tremorgenic mycotoxins, fumitremorgin A and B.
Topics: Animals; Aspartic Acid; Behavior, Animal; Brain; Chlorpromazine; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Haloperidol; Harmine; Indenes; Indoles; Lethal Dose 50; Male; Mice; Perphenazine; Posture; Reserpine; Seizures; Spiperone; Triflupromazine | 1986 |
Effects of continuous administration for 12 months of amine-depleting drugs and chlorpromazine on striatal dopamine function in the rat.
Topics: Animals; Apomorphine; Body Weight; Chlorpromazine; Corpus Striatum; Dopamine; Homovanillic Acid; Indoles; Kinetics; Male; Motor Activity; Piperazines; Rats; Rats, Inbred Strains; Reserpine; Spiperone; Stereotyped Behavior; Thioxanthenes | 1987 |
Potency of antipsychotics in reversing the effects of a hallucinogenic drug on locus coeruleus neurons correlates with 5-HT2 binding affinity.
Topics: Amphetamines; Animals; Antipsychotic Agents; Chlorpromazine; Clozapine; DOM 2,5-Dimethoxy-4-Methylamphetamine; Electric Stimulation; Evoked Potentials; Haloperidol; Locus Coeruleus; Male; Neurons; Rats; Rats, Inbred Strains; Receptors, Serotonin; Sciatic Nerve; Spiperone; Sulpiride | 1988 |
Serial [18F]N-methylspiroperidol PET studies to measure changes in antipsychotic drug D-2 receptor occupancy in schizophrenic patients.
Topics: Adult; Binding, Competitive; Chlorpromazine; Corpus Striatum; Haloperidol; Humans; Male; Middle Aged; Receptors, Dopamine; Receptors, Dopamine D2; Schizophrenia; Spiperone; Tomography, Emission-Computed | 1988 |
Simultaneous catalepsy and apomorphine-induced stereotypic behavior in mice.
Topics: Animals; Apomorphine; Catalepsy; Chlorpromazine; Domperidone; Drug Interactions; Haloperidol; Injections, Intraventricular; Mice; Spiperone; Stereotyped Behavior; Sulpiride | 1985 |
Modification by propranolol and related compounds of motor activity and stereotype behaviour induced in the rat by amphetamine.
Topics: Amphetamine; Animals; Behavior; Chlorpromazine; Dose-Response Relationship, Drug; Humans; Male; Motor Activity; Moxisylyte; Norepinephrine; Oxprenolol; Practolol; Propranolol; Rats; Spiperone; Stereotyped Behavior; Stimulation, Chemical | 1974 |
Inhibitory role of dopamine and 5-hydroxytryptamine in the sexual behaviour of female rats.
Topics: Adrenal Glands; Adrenalectomy; Animals; Castration; Chlorpromazine; Depression, Chemical; Dioxoles; Disulfides; Dopamine Antagonists; Estradiol; Female; Fenclonine; Fenfluramine; Imidazoles; Male; Methyltyrosines; Norepinephrine; Ovary; Pimozide; Piperazines; Progesterone; Rats; Serotonin Antagonists; Sexual Behavior, Animal; Spiperone; Stimulation, Chemical; Time Factors | 1974 |
Interaction of oxypertine with rat brain monoamine receptors.
Topics: Adenylyl Cyclases; Animals; Biogenic Amines; Cerebral Cortex; Chlorpromazine; Corpus Striatum; Dopamine; Haloperidol; In Vitro Techniques; Indoles; Male; Piperazines; Rats; Receptors, Neurotransmitter; Spiperone | 1980 |
Dopamine receptor blockade by imidoline and its proposed active conformation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenylyl Cyclase Inhibitors; Animals; Antipsychotic Agents; Binding Sites; Chlorpromazine; Imidazoles; Male; Molecular Conformation; Rats; Receptors, Dopamine; Spiperone; Structure-Activity Relationship | 1980 |
Neuroleptic drug-induced dopamine receptor supersensitivity: antagonism by L-prolyl-L-leucyl-glycinamide.
Topics: Animals; Butyrophenones; Chlorpromazine; Corpus Striatum; Haloperidol; Kinetics; Male; MSH Release-Inhibiting Hormone; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone | 1981 |
Decreased disrupting effect of neuroleptics on conditioned avoidance in rats with lesions in the mid-brain raphe nuclei.
Topics: Animals; Antipsychotic Agents; Avoidance Learning; Brain Stem; Chlorpromazine; Conditioning, Classical; Haloperidol; Male; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Spiperone | 1982 |
Remoxipride, a new potential antipsychotic compound with selective antidopaminergic actions in the rat brain.
Topics: Adenylyl Cyclases; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Benzamides; Binding, Competitive; Brain Chemistry; Catalepsy; Chlorpromazine; Dogs; Female; Haloperidol; Histocytochemistry; Humans; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Remoxipride; Spiperone; Sulpiride; Thioridazine; Vomiting | 1984 |
The residual effect of chronic neuroleptic treatment on the neuroleptic binding assay in rats.
Topics: Animals; Brain; Butyrophenones; Chlorpromazine; Corpus Striatum; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone | 1983 |
Factors affecting solubilized dopamine-sensitive adenylate cyclase.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Cattle; Chlorpromazine; Corpus Striatum; Dopamine; Enzyme Activation; Guanylyl Imidodiphosphate; Haloperidol; Lipids; Magnesium; Solubility; Spiperone | 1983 |
Reversal of respiratory responses to dopamine after dopamine antagonists.
Topics: Animals; Apomorphine; Cats; Chlorpromazine; Dopamine; Dopamine Antagonists; Female; Haloperidol; Male; Nitrogen; Oxygen; Perphenazine; Respiration; Spiperone | 1982 |
Chlorpromazine methiodide-induced barrel rotation: an antimuscarinic effect.
Topics: Animals; Binding, Competitive; Brain; Cell Membrane; Chlorpromazine; Corpus Striatum; Kinetics; Male; Motor Activity; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Receptors, Dopamine; Receptors, Muscarinic; Rotation; Spiperone | 1982 |
Regional blockade by neuroleptic drugs of in vivo 3H-spiperone binding in the rat brain. Relation to blockade of apomorphine induced hyperactivity and stereotypies.
Topics: Animals; Apomorphine; Binding, Competitive; Brain; Butyrophenones; Chlorpromazine; Clozapine; Haloperidol; Humans; Hyperkinesis; Kinetics; Organ Specificity; Rats; Receptors, Dopamine; Receptors, Drug; Spiperone; Stereotyped Behavior; Sulpiride; Thioridazine | 1981 |
Interaction of AZA analogs of chlorpromazine with the dopamine D2 receptor.
Topics: Acetylcholine; Animals; Apomorphine; Aza Compounds; Binding, Competitive; Chlorpromazine; Corpus Striatum; In Vitro Techniques; Male; Mice; Potassium; Quaternary Ammonium Compounds; Receptors, Dopamine D2; Spiperone | 1993 |
Long-term neuroleptic treatments counteract dopamine D2 agonist inhibition of adenylate cyclase but do not affect pertussis toxin ADP-ribosylation in the rat brain.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Antipsychotic Agents; Benzazepines; Brain; Brain Chemistry; Chlorpromazine; Dopamine Agonists; Dopamine Antagonists; Haloperidol; Male; Neostriatum; Pertussis Toxin; Rats; Rats, Wistar; Receptors, Dopamine D2; Spiperone; Virulence Factors, Bordetella | 1996 |
Dopamine receptor antagonists modulate glucose uptake in rat pheochromocytoma (PC12) cells.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antipsychotic Agents; Benzazepines; Biological Transport; Chlorpromazine; Clozapine; Dizocilpine Maleate; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Excitatory Amino Acid Antagonists; Fluphenazine; Glucose; Haloperidol; PC12 Cells; Pimozide; Rats; Receptors, Dopamine D2; Spiperone; Sulpiride; Tritium | 1999 |
Mechanisms of inverse agonism of antipsychotic drugs at the D(2) dopamine receptor: use of a mutant D(2) dopamine receptor that adopts the activated conformation.
Topics: 1-Methyl-3-isobutylxanthine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Apomorphine; Binding, Competitive; Bromocriptine; Butaclamol; Chlorpromazine; CHO Cells; Clozapine; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; GTP-Binding Proteins; Haloperidol; Humans; Macromolecular Substances; Mutagenesis, Site-Directed; Phenethylamines; Piperidines; Protein Binding; Protein Conformation; Radioligand Assay; Receptors, Dopamine D2; Recombinant Fusion Proteins; Sodium; Spiperone; Structure-Activity Relationship; Sulpiride; Transfection; Tyramine | 2001 |
Timing is everything: the effects of putative dopamine antagonists on metamorphosis vary with larval age and experimental duration in the prosobranch gastropod Crepidula fornicata.
Topics: Animals; Benzazepines; Chlorpromazine; Dopamine; Dopamine Antagonists; Enzyme Inhibitors; Larva; Metamorphosis, Biological; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Signal Transduction; Snails; Spiperone | 2002 |
Involvement of the first transmembrane segment of human α(2) -adrenoceptors in the subtype-selective binding of chlorpromazine, spiperone and spiroxatrine.
Topics: Adrenergic alpha-2 Receptor Antagonists; Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Cell Culture Techniques; Chlorpromazine; CHO Cells; Cricetinae; Cricetulus; Dioxanes; Humans; Ligands; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Structure, Secondary; Receptors, Adrenergic, alpha-2; Sequence Alignment; Spiperone; Spiro Compounds; Transfection | 2011 |
Dopamine as an anorectic neuromodulator in the cockroach Rhyparobia maderae.
Topics: Animals; Chlorpromazine; Cockroaches; Dopamine; Dopamine Agonists; Dopamine Antagonists; Eating; Neurotransmitter Agents; Spiperone; Tetrahydronaphthalenes | 2011 |