chlorpromazine and rifampin

chlorpromazine has been researched along with rifampin in 33 studies

Research

Studies (33)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (15.15)	18.7374
1990's	0 (0.00)	18.2507
2000's	9 (27.27)	29.6817
2010's	18 (54.55)	24.3611
2020's	1 (3.03)	2.80

Authors

Authors	Studies
Strassburg, CP; Tukey, RH	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Aínsa, JA; Martín, C; Ramón-García, S; Thompson, CJ	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S	1
Bucar, F; Gröblacher, B; Kunert, O	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chibale, K; Kigondu, EM; Warner, DF; Wasuna, A	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Barreca, ML; Bojarski, AJ; Cecchetti, V; Cook, GM; Desantis, J; Felicetti, T; Franzblau, SG; Handzlik, J; Hards, K; Kolář, MH; Latacz, G; Manfroni, G; Massari, S; Mazzarella, MA; Nakatani, Y; Nizi, MG; Rushton-Green, R; Sabatini, S; Satała, G; Shetye, G; Tabarrini, O	1
Calissendorff, B	1
Crepaldi, G; Jemmolo, RM; Lirussi, F; Muraca, M; Nassuato, G; Okolicsanyi, L; Orlando, R; Strazzabosco, M	1
Nugent, KM; Wood, NC	1
Berthelot, P	1
Greim, H	1
Amaral, L; Viveiros, M	1
Kang, DH; Kwon, JS; Shim, G	1
Amaral, L; Baptista, P; Couto, I; Machado, D; Perdigão, J; Portugal, I; Rodrigues, L; Veigas, B; Viveiros, M	1

Reviews

6 review(s) available for chlorpromazine and rifampin

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
Pharmacologically active metabolites, combination screening and target identification-driven drug repositioning in antituberculosis drug discovery. Bioorganic & medicinal chemistry, 2014, Aug-15, Volume: 22, Issue:16 Topics: Animals; Anti-Bacterial Agents; Antitubercular Agents; Drug Discovery; Fusidic Acid; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Tuberculosis	2014
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
The effect of drugs on bile flow and composition. An overview. Drugs, 1986, Volume: 31, Issue:5 Topics: Animals; Bile; Bile Acids and Salts; Cats; Chlorpromazine; Cholagogues and Choleretics; Cholesterol; Clofibrate; Colchicine; Cricetinae; Dehydrocholic Acid; Diuretics; Dogs; Enterohepatic Circulation; Estrogens; Glucagon; Guinea Pigs; Humans; Insulin; Liver; Macaca mulatta; Phospholipids; Rabbits; Rats; Rifampin; Rifamycins; Somatostatin; Theophylline; Ursodeoxycholic Acid	1986
Mechanisms and prediction of drug-induced liver disease. Gut, 1973, Volume: 14, Issue:4 Topics: Adenosine Triphosphate; Age Factors; Animals; Bilirubin; Biotransformation; Carbon Isotopes; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chlordiazepoxide; Chlorpromazine; Cholestasis; Dogs; Humans; Infant, Newborn; Liver; Liver Diseases; Mice; Microsomes, Liver; Phenylbutazone; Rats; Rifampin; RNA	1973
[Enzyme induction in the liver changes drug activity]. Medizinische Klinik, 1980, Sep-26, Volume: 75, Issue:20 Topics: Animals; Barbiturates; Carbamazepine; Chlorpromazine; Drug Interactions; Enzyme Induction; Glutethimide; Humans; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Pharmaceutical Preparations; Phenylbutazone; Phenytoin; Rifampin; Time Factors	1980

Other Studies

27 other study(ies) available for chlorpromazine and rifampin

Article	Year
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Role of the Mycobacterium tuberculosis P55 efflux pump in intrinsic drug resistance, oxidative stress responses, and growth. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:9 Topics: Antitubercular Agents; Bacterial Proteins; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Clofazimine; Dithiothreitol; Drug Resistance, Multiple, Bacterial; Gene Expression Regulation, Bacterial; Glutathione; Hydrogen Peroxide; Membrane Transport Proteins; Mutation; Mycobacterium tuberculosis; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Rifampin; Valinomycin	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Species independence in brain tissue binding using brain homogenates. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7 Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors	2012
Compounds of Alpinia katsumadai as potential efflux inhibitors in Mycobacterium smegmatis. Bioorganic & medicinal chemistry, 2012, Apr-15, Volume: 20, Issue:8 Topics: Alpinia; Antibiotics, Antitubercular; Antitubercular Agents; Diarylheptanoids; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium smegmatis; Plant Extracts; Seeds	2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
Antitubercular polyhalogenated phenothiazines and phenoselenazine with reduced binding to CNS receptors. European journal of medicinal chemistry, 2020, Sep-01, Volume: 201 Topics: Animals; Antitubercular Agents; Chlorocebus aethiops; Drug Synergism; Enzyme Inhibitors; HEK293 Cells; Humans; Microsomes, Liver; Molecular Structure; Mycobacterium smegmatis; Mycobacterium tuberculosis; NADH Dehydrogenase; Organoselenium Compounds; Parasitic Sensitivity Tests; Phenothiazines; Protein Binding; Receptors, Dopamine D2; Receptors, Serotonin; Structure-Activity Relationship; Vero Cells	2020
Melanotropic drugs and retinal functions. II. Effects of phenothiazine and rifampicin on the sheep ERG. Acta ophthalmologica, 1976, Volume: 54, Issue:1 Topics: Animals; Chlorpromazine; Electroretinography; Pigment Epithelium of Eye; Promethazine; Retina; Rifampin; Sheep	1976
Inhibitory effects of chlorpromazine on Candida species. Antimicrobial agents and chemotherapy, 1985, Volume: 27, Issue:5 Topics: Amphotericin B; Candida; Chlorpromazine; Drug Interactions; Microbial Sensitivity Tests; Rifampin; Time Factors	1985
Enhancement of antibiotic activity against poly-drug resistant Mycobacterium tuberculosis by phenothiazines. International journal of antimicrobial agents, 2001, Volume: 17, Issue:3 Topics: Antibiotics, Antitubercular; Chlorpromazine; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Synergism; Humans; Immunologic Factors; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Phenothiazines; Promethazine; Rifampin; Streptomycin; Thioridazine	2001
Probable case of neuroleptic malignant syndrome following administration of antituberculotic drugs in a chlorpromazine-treated patient. Journal of Korean medical science, 2008, Volume: 23, Issue:4 Topics: Adult; Antitubercular Agents; Chlorpromazine; Creatine Kinase; Drug Interactions; Enzyme Induction; Humans; Male; Neuroleptic Malignant Syndrome; Rifampin; Schizophrenia	2008
Contribution of efflux to the emergence of isoniazid and multidrug resistance in Mycobacterium tuberculosis. PloS one, 2012, Volume: 7, Issue:4 Topics: Antitubercular Agents; Bacterial Proteins; Biological Transport, Active; Carrier Proteins; Catalase; Chlorpromazine; DNA-Directed RNA Polymerases; Drug Resistance, Multiple, Bacterial; Gene Expression; Humans; Isoniazid; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Rifampin; Thioridazine; Tuberculosis, Multidrug-Resistant; Verapamil	2012