chlorpromazine has been researched along with quinacrine in 88 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 53 (60.23) | 18.7374 |
| 1990's | 10 (11.36) | 18.2507 |
| 2000's | 17 (19.32) | 29.6817 |
| 2010's | 7 (7.95) | 24.3611 |
| 2020's | 1 (1.14) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Chiang, GH; Unger, SH | 1 |
| Horvath, D | 1 |
| Pajeva, I; Wiese, M | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Elshorst, B; Fiebig, K; Griesinger, C; Grimme, S; Jacobs, DM; Vogtherr, M; Zahn, R | 1 |
| Cohen, FE; Legname, G; May, BC; Prusiner, SB; Sherrill, J; Wallace, AC; Witkop, J; Zorn, JA | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Fitos, I; Mády, G; Visy, J; Zsila, F | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Dalvie, D; Hu, Q; Jones, P; Obach, RS; Pryde, DC; Tran, TD | 1 |
| Atzpodien, EA; Csato, M; Doessegger, L; Fischer, H; Lenz, B; Schmitt, G; Singer, T | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Kitagawa, T; Matsumoto, A; Terashima, I; Uesono, Y | 1 |
| Drenckhahn, D; Lüllmann-Rauch, R | 1 |
| Benveniste, J; Cazenave, JP; Mustard, JF | 1 |
| Garfinkel, E; Hirschman, SZ | 1 |
| Da Prada, M; Picotti, GB; Pletscher, A | 1 |
| Capito, K; Gembal, M; Hedeskov, CJ; Malik, T; Thams, P | 1 |
| Ichikawa, M; Matsumoto, G; Urayama, M | 1 |
| Belzer, FO; Claesson, K; Lindell, S; Southard, JH | 1 |
| Belzer, FO; McAnulty, JF; Southard, JH; Vreugdenhil, PK | 1 |
| DiPaola, M; Kao, PN; Karlin, A | 1 |
| Safa, AR; Spearman, T; Van Dyke, K; Ye, ZG | 1 |
| Crosland, RD | 1 |
| Ungemach, FR | 1 |
| Borowitz, SM; Montgomery, C | 1 |
| Duncan, CJ | 1 |
| Nakagawa, Y; Waku, K | 1 |
| Galat, A | 1 |
| Arany, E; Bonetto, R; del Castillo, E; Uranga, J | 1 |
| Beckman, JK; Borowitz, SM; Burr, IM | 1 |
| Dargent-Salée, ML | 1 |
| Brodinova, NS; Moroz, AF | 1 |
| Brodinova, NS; Moroz, AF; Podboronov, VM | 1 |
| Lijinsky, W | 1 |
| Garbus, J; Weinbach, EC | 1 |
| De Zoeten, LW; Tipker, J | 1 |
| Hotta, SS; Tarantino, LM | 1 |
| Greengard, P; Quinn, GP; Reid, MB | 1 |
| Stoliarov, GV | 1 |
| Tosk, J | 1 |
| Mason, RG; Read, MS; Saba, SR; Shermer, RW | 1 |
| Gross, E; San Pietro, A | 1 |
| Avron, M; Shavit, N | 1 |
| Dilley, RA | 1 |
| Grudev, FI | 1 |
| Greenberg, RN; Guerrant, RL; Murad, F | 1 |
| Allison, WS; Laikind, PK | 1 |
| Klaassen, CD; Stacey, NH | 1 |
| Lasslo, A | 1 |
| Chang, HH; Galton, N; Lampe, RA; Magruder, CD; Michaelis, EK; Michaelis, ML | 1 |
| Brammer, JP; Maguire, MH | 1 |
| Kodama, H; Mikasa, H; Miyahara, M; Okimasu, E; Terada, S; Utsumi, K | 1 |
| Harris, EJ; Jackson, MJ; Jones, DA | 1 |
| García-Sancho, J; Herreros, B; Sanchez, A | 1 |
| Feinstein, MB; Opas, EE; Walenga, RW | 1 |
| Brammer, JP; Maguire, MH; Walaszek, EJ; Wiley, RA | 1 |
| Haigler, HT; Pastan, I; Willingham, MC | 1 |
| Andersson, A; Olsson, S; Tjälve, H | 1 |
| Lee, CP; Mueller, DM | 1 |
| Araki, H; Lefer, AM; Peck, RC | 1 |
| Futai, M; Moriyama, Y; Patel, V | 1 |
| McNamee, MG; Tamamizu, S; Todd, AP | 1 |
| Kristufek, D; Kubicek, CP; Mach, RL; Zeilinger, S | 1 |
| Cohen, FE; Korth, C; May, BC; Prusiner, SB | 1 |
| Love, R | 1 |
| Josefson, D | 1 |
| Adjou, KT; Auvré, F; Barret, A; Bate, C; Colombo, L; De Luigi, A; Deslys, JP; Forloni, G; Lasmézas, C; Limido, L; Rossi, G; Salès, N; Salmona, M; Suardi, S; Tagliavini, F; Williams, A | 1 |
| LOW, H | 1 |
| GALUSZKA, J; SZAFLARSKI, J | 1 |
| MAEKAWA, M; NOHARA, Y | 1 |
| DOAN, CA | 1 |
| GRILLO, MA; RINAUDO, MT; VERGANI, E | 1 |
| CURRIE, WD; PENNIALL, R | 1 |
| BARTL, P; KORB, J; RIMAN, J | 1 |
| MARUCHIN, JE; TYSAROWSKI, W | 1 |
| Kuroda, Y | 1 |
| Kuroda, Y; Nanri, Y | 1 |
| Benito-León, J | 1 |
| Bermejo, J; Contreras, MA; Guerrero, MC; Lunar, A; Martínez Pérez, M; Martínez-Lage, JF; Rábano, A | 1 |
| Bach, S; Blondel, M; Nagy, PD; Sasvari, Z | 1 |
| Bach, S; Blondel, M; Desban, N; Galons, H; Gug, F; Oumata, N; Tribouillard-Tanvier, D; Voisset, C | 1 |
4 review(s) available for chlorpromazine and quinacrine
| Article | Year |
|---|---|
Blood platelet function, medicinal agents, and other chemical entities.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Amines; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Blood Vessels; Calcium; Cell Membrane; Chlorpromazine; Dipyridamole; Humans; Papaverine; Phospholipids; Platelet Aggregation; Propranolol; Quinacrine; Structure-Activity Relationship; Tretoquinol | 1984 |
[THERAPY OF EXPERIMENTAL TOXOPLASMOSIS].
Topics: Antimalarials; Arsenicals; Chlorpromazine; Chlortetracycline; Cinchona; Humans; Oxytetracycline; Proguanil; Quinacrine; Quinine; Research; Sulfonamides; Toxoplasmosis | 1963 |
[Gerstmann-Sträussler-Scheinker syndrome].
Topics: Animals; Chlorpromazine; Gerstmann-Straussler-Scheinker Disease; Humans; Magnetic Resonance Angiography; Molecular Diagnostic Techniques; Mutation; Prions; Quinacrine | 2003 |
[Creutzfeldt-Jakob disease].
Topics: Antimalarials; Antipsychotic Agents; Biomarkers; Brain; Chlorpromazine; Creutzfeldt-Jakob Syndrome; Diagnosis, Differential; Drug Therapy, Combination; Humans; Magnetic Resonance Imaging; Phosphopyruvate Hydratase; Prions; Quinacrine | 2004 |
84 other study(ies) available for chlorpromazine and quinacrine
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
Topics: Amines; Animals; Buffers; Chromatography, High Pressure Liquid; Histamine Release; Lipid Metabolism; Octanols; Protein Binding; Rats; Serum Albumin, Bovine; Sodium-Potassium-Exchanging ATPase; Solubility; Structure-Activity Relationship | 1981 |
A virtual screening approach applied to the search for trypanothione reductase inhibitors.
Topics: Algorithms; Databases, Factual; Enzyme Inhibitors; Models, Chemical; Molecular Conformation; NADH, NADPH Oxidoreductases; Thermodynamics | 1997 |
Molecular modeling of phenothiazines and related drugs as multidrug resistance modifiers: a comparative molecular field analysis study.
Topics: Antineoplastic Agents; Cell Survival; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Molecular Conformation; Phenothiazines; Thioxanthenes; Tumor Cells, Cultured | 1998 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Antimalarial drug quinacrine binds to C-terminal helix of cellular prion protein.
Topics: Antimalarials; Binding Sites; Chloroquine; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Peptide Fragments; Phenothiazines; Prions; Protein Structure, Secondary; Quinacrine; Recombinant Proteins; Structure-Activity Relationship | 2003 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Structure-activity relationship study of prion inhibition by 2-aminopyridine-3,5-dicarbonitrile-based compounds: parallel synthesis, bioactivity, and in vitro pharmacokinetics.
Topics: Aminopyridines; Animals; Cell Line, Tumor; Combinatorial Chemistry Techniques; Membranes, Artificial; Mice; Models, Molecular; Nitriles; Permeability; PrPSc Proteins; Solubility; Structure-Activity Relationship | 2007 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Selective plasma protein binding of antimalarial drugs to alpha1-acid glycoprotein.
Topics: Antimalarials; Binding Sites; Chromatography, Affinity; Circular Dichroism; Humans; Molecular Structure; Orosomucoid; Protein Binding; Serum Albumin; Spectrophotometry; Stereoisomerism; Structure-Activity Relationship | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Aldehyde oxidase: an enzyme of emerging importance in drug discovery.
Topics: Aldehyde Oxidase; Animals; Drug Discovery; Humans; Models, Molecular; Organ Specificity; Oxidation-Reduction; Pharmaceutical Preparations; Pharmacokinetics; Species Specificity; Substrate Specificity | 2010 |
In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets.
Topics: Animals; Cattle; Cells, Cultured; Computer Simulation; Cornea; Drug-Related Side Effects and Adverse Reactions; Fibroblasts; Lipidoses; Lysosomal Storage Diseases; Models, Molecular; Pharmaceutical Preparations; Phospholipids; Structure-Activity Relationship; Thermodynamics | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Antimalarial Quinacrine and Chloroquine Lose Their Activity by Decreasing Cationic Amphiphilic Structure with a Slight Decrease in pH.
Topics: Antifungal Agents; Cell Membrane; Chloroquine; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Molecular Structure; Monosaccharide Transport Proteins; Protons; Quinacrine; Saccharomyces cerevisiae; Surface-Active Agents | 2021 |
Experimental myopathy induced by amphiphilic cationic compounds including several psychotropic drugs.
Topics: Amitriptyline; Animals; Chloroquine; Chlorphentermine; Chlorpromazine; Female; Imipramine; Iprindole; Male; Microscopy, Electron; Muscles; Muscular Diseases; Phentermine; Piperazines; Psychotropic Drugs; Quinacrine; Rats; Triparanol | 1979 |
Aggregation of rabbit platelets by platelet-activating factor is independent of the release reaction and the arachidonate pathway and inhibited by membrane-active drugs.
Topics: Animals; Arachidonic Acids; Blood Platelets; Cell Membrane; Chlorpromazine; Edetic Acid; Egtazic Acid; Fibrinogen; Humans; Imipramine; Lidocaine; Methylprednisolone; Platelet Aggregation; Prostaglandins; Quinacrine; Rabbits; Reserpine; Serotonin | 1979 |
Inhibition of hepatitis B DNA polymerase by intercalating agents.
Topics: Chloroquine; Chlorpromazine; Drug Synergism; Ethidium; Hepatitis B; Hepatitis B virus; Humans; Indicators and Reagents; Methylene Blue; Nucleic Acid Synthesis Inhibitors; Primaquine; Quinacrine | 1978 |
Uptake and liberation of mepacrine in blood platelets.
Topics: 2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-; Animals; Blood Platelets; Cell Membrane; Chlorpromazine; Cocaine; Cyanides; Female; Fluorides; Guinea Pigs; Imipramine; In Vitro Techniques; Male; Ouabain; Quinacrine; Reserpine; Serotonin; Temperature; Thrombin | 1976 |
Characteristics of phosphoinositide-specific phospholipase C activity from mouse pancreatic islets.
Topics: Animals; Arachidonic Acid; Calcium; Chlorpromazine; Cyclic AMP; Glucose; Glyceraldehyde 3-Phosphate; Indomethacin; Islets of Langerhans; Male; Mice; Phosphatidylinositols; Putrescine; Quinacrine; Spermine; Substrate Specificity; Tetracaine; Type C Phospholipases | 1991 |
Anticalmodulin drugs block the sodium gating current of squid giant axons.
Topics: Animals; Axons; Biological Transport, Active; Calmodulin; Chlorpromazine; Decapodiformes; Diazepam; Imidazoles; Ion Channel Gating; Membrane Potentials; Phenothiazines; Potassium; Quinacrine; Sodium; Sulfonamides; Trifluoperazine | 1991 |
Chlorpromazine, quinacrine, and verapamil as donor pretreatment in liver preservation, tested in the isolated perfused rat liver.
Topics: Animals; Bile; Chlorpromazine; Cold Temperature; Cryoprotective Agents; Drug Evaluation, Preclinical; Enzymes; In Vitro Techniques; Liver; Male; Organ Preservation; Perfusion; Quinacrine; Rats; Rats, Inbred Strains; Tissue Donors; Verapamil | 1991 |
Improved survival of kidneys preserved for seven days with a phospholipase inhibitor.
Topics: Animals; Calcium; Chlorpromazine; Dogs; Female; Graft Survival; In Vitro Techniques; Kidney Cortex; Kidney Transplantation; Mitochondria; Organ Preservation; Oxygen Consumption; Phospholipases; Quinacrine | 1991 |
Mapping the alpha-subunit site photolabeled by the noncompetitive inhibitor [3H]quinacrine azide in the active state of the nicotinic acetylcholine receptor.
Topics: Acetylcholine; Affinity Labels; Amino Acid Sequence; Amphibian Venoms; Animals; Azides; Binding Sites; Bupivacaine; Chlorpromazine; Chromatography, High Pressure Liquid; Cyanogen Bromide; Molecular Sequence Data; Molecular Weight; Nicotinic Antagonists; Peptide Fragments; Peptide Mapping; Photochemistry; Proadifen; Quinacrine; Receptors, Nicotinic; Torpedo | 1990 |
3H-azidopine photoaffinity labeling of high molecular weight proteins in chloroquine resistant falciparum malaria.
Topics: Affinity Labels; Animals; Azides; Binding, Competitive; Chloroquine; Chlorpromazine; Dihydropyridines; Drug Resistance; Glycoproteins; Molecular Weight; Nicardipine; Photochemistry; Plasmodium falciparum; Proteins; Quinacrine; Reserpine; Trifluoperazine; Verapamil | 1989 |
Effect of chlorpromazine and quinacrine on the lethality in mice of the venoms and neurotoxins from several snakes.
Topics: Animals; Chlorpromazine; Crotalid Venoms; Dose-Response Relationship, Drug; Elapid Venoms; Female; Mice; Mice, Inbred ICR; Neurotoxins; Phospholipases A; Quinacrine | 1989 |
Prevention of liver cell damage following lipid peroxidation by depression of lysophosphatide formation.
Topics: Animals; Bromotrichloromethane; Chemical and Drug Induced Liver Injury; Chlorpromazine; Enzyme Activation; Lipid Peroxidation; Liver; Lysophospholipids; Male; Phospholipases A; Quinacrine; Rats; Rats, Inbred Strains | 1989 |
The role of phospholipase A2 in microsomal lipid peroxidation induced with t-butyl hydroperoxide.
Topics: Acetophenones; Animals; Chlorpromazine; Enzyme Activation; Fatty Acids; Lipid Peroxidation; Melitten; Microsomes, Liver; Peroxides; Phospholipases; Phospholipases A; Phospholipases A2; Quinacrine; Rats; tert-Butylhydroperoxide; Thiobarbiturates | 1989 |
The role of phospholipase A2 in calcium-induced damage in cardiac and skeletal muscle.
Topics: Animals; Calcium; Chlorpromazine; Enzyme Inhibitors; In Vitro Techniques; Indomethacin; Lipoxygenase; Mice; Mice, Inbred BALB C; Microscopy, Electron; Mitochondria; Muscles; Myocardium; Phospholipases; Phospholipases A; Phospholipases A2; Prostaglandin-Endoperoxide Synthases; Quinacrine; Rana temporaria; Sarcoplasmic Reticulum | 1988 |
Selective inhibition of free arachidonic acid production in activated alveolar macrophages by calmodulin antagonists.
Topics: Acetophenones; Animals; Arachidonic Acid; Arachidonic Acids; Calmodulin; Chlorpromazine; Chromatography, High Pressure Liquid; Cytochalasin B; Linoleic Acid; Linoleic Acids; Macrophage Activation; Macrophages; Oleic Acid; Oleic Acids; Opsonin Proteins; Phosphatidylcholines; Phosphatidylinositols; Phospholipases A; Pulmonary Alveoli; Quinacrine; Rabbits; Sulfonamides; Trifluoperazine; Zymosan | 1988 |
Interaction of riboflavin binding protein with riboflavin, quinacrine, chlorpromazine and daunomycin.
Topics: Carrier Proteins; Chlorpromazine; Circular Dichroism; Daunorubicin; Fluorescence; Mathematics; Membrane Transport Proteins; Quinacrine; Riboflavin | 1988 |
Effect of glomerulopressin on several isolated veins and arteries of different species.
Topics: Animals; Arteries; Chlorpromazine; Cricetinae; Dogs; Glucuronates; Glucuronidase; Muscle Contraction; Muscle, Smooth, Vascular; Quinacrine; Rabbits; Rats; Veins | 1987 |
The role of phospholipase A activity in rat liver microsomal lipid peroxidation.
Topics: Acetophenones; Adenosine Diphosphate; Alloxan; Animals; Chlorpromazine; Copper; Ferrous Compounds; Glutathione; Hydrogen-Ion Concentration; Lipid Peroxides; Male; Microsomes, Liver; Phospholipases; Phospholipases A; Phospholipases A1; Phospholipases A2; Quinacrine; Rats; Rats, Inbred Strains | 1987 |
[Some properties of the ATPases of frog skin].
Topics: Adenosine Triphosphatases; Amobarbital; Animals; Anura; Biological Transport, Active; Chlorpromazine; Enzyme Activation; Imines; Ouabain; Potassium; Promethazine; Quinacrine; Quinones; Skin; Sodium | 1970 |
[The increase of resistance of Staphylococcus and Escherichia coli to some antibiotics and their combinations with DNA-tropic substances].
Topics: Acridines; Ampicillin; Anti-Bacterial Agents; Antimetabolites; Azaguanine; Chlorpromazine; Escherichia coli; Flavonoids; Mercaptopurine; Neomycin; Novobiocin; Penicillin Resistance; Penicillins; Phenothiazines; Protamines; Quinacrine; Ristocetin; Staphylococcus; Streptomycin; Vasodilator Agents | 1970 |
[Prevention of the development of drug resistant forms of staphylococci by a combination of antibiotics with DNA-tropic compounds].
Topics: Acridines; Anti-Bacterial Agents; Azaguanine; Chlorpromazine; Culture Media; Depression, Chemical; DNA, Bacterial; Flavonoids; Mercaptopurine; Mutation; Novobiocin; Penicillin Resistance; Penicillins; Phenothiazines; Quinacrine; Staphylococcus; Time Factors; Vasodilator Agents | 1971 |
Reaction of drugs with nitrous acid as a source of carcinogenic nitrosamines.
Topics: Amines; Aminopyrine; Chemical Phenomena; Chemistry; Chlorpheniramine; Chlorpromazine; Cyclizine; Dextropropoxyphene; Disulfiram; Histamine H1 Antagonists; Lucanthone; Methadone; Nitrites; Nitrosamines; Quinacrine; Tolazamide | 1974 |
Mechanism of action of reagents that uncouple oxidative phosphorylation.
Topics: Antimetabolites; Benzimidazoles; Bilirubin; Butyrophenones; Chemical Phenomena; Chemistry; Chlorpromazine; Cyanides; Depression, Chemical; Dicumarol; Dinitrophenols; Indicators and Reagents; Lipoproteins; Mitochondria; Niclosamide; Oleic Acids; Oxidative Phosphorylation; Phenols; Phenylbutazone; Protein Binding; Quinacrine; Salicylates; Thiopental; Thyroxine; Tyrothricin | 1969 |
Intermediary metabolism of the liver fluke Fasciola hepatica, II. Hydrogen transport and phosphorylation.
Topics: Amobarbital; Animals; Antimycin A; Biological Transport; Chlorpromazine; Depression, Chemical; Dicumarol; Dinitrophenols; Electron Transport Complex IV; Fasciola hepatica; Fumarates; Hexosephosphates; Hydrogen; Mitochondria, Liver; NAD; Oxidative Phosphorylation; Oxidoreductases; Quinacrine; Rats; Rotenone; Succinate Dehydrogenase | 1969 |
Quinacrine stimulation of glutathione reduction dependent on the presence of a particulate brain subfraction.
Topics: Animals; Brain; Cell Fractionation; Chlorpromazine; Glutathione; Guinea Pigs; In Vitro Techniques; Male; Niacinamide; Oxidation-Reduction; Quinacrine; Stimulation, Chemical; Subcellular Fractions | 1974 |
Prevention by antidepressant drugs of reserpine effect on pyridine nucleotide metabolism.
Topics: Aminopyrine; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Atropine; Benactyzine; Caffeine; Chlorpheniramine; Chlorpromazine; Female; Hexobarbital; Hydralazine; Hypothalamus; Imipramine; Iproniazid; Isoniazid; Liver; Meprobamate; Methacholine Compounds; Morphine; NAD; Niacinamide; Pargyline; Pentobarbital; Phenylbutazone; Phenytoin; Quinacrine; Rats; Reserpine; Tranylcypromine; Tripelennamine; Zoxazolamine | 1966 |
[On the course of drug psychoses].
Topics: Adrenocorticotropic Hormone; Adult; Atropine; Barbiturates; Chlorpromazine; Disulfiram; Drug Hypersensitivity; Female; Humans; Isoniazid; Male; Prednisolone; Psychoses, Substance-Induced; Quinacrine; Time Factors | 1968 |
Chlorpromazine protection against acridine-induced reversion of a histidine-requiring mutant of Salmonella typhimurium.
Topics: Acridines; Chlorpromazine; Culture Media; Histidine; Mutagens; Mutation; Quinacrine; Salmonella typhimurium | 1974 |
Apparent similarity of mechanisms of platelet adhesion and aggregation. Differentiation of these functions from clot retraction.
Topics: Amitriptyline; Aspirin; Blood Coagulation Tests; Caffeine; Chloromercuribenzoates; Chlorpromazine; Clot Retraction; Cocaine; Diphenhydramine; Ethacrynic Acid; Guanidines; Humans; Phenothiazines; Phentolamine; Phenylbutazone; Platelet Adhesiveness; Promethazine; Quinacrine; Quinidine; Reserpine; Sulfinpyrazone; Sulfones; Tosyl Compounds | 1972 |
Interaction of uncouplers and energy transfer inhibitors with high-energy states of chloroplasts.
Topics: Ammonium Chloride; Anti-Bacterial Agents; Arsenic; Chemical Phenomena; Chemistry; Chlorine; Chloroplasts; Chlorpromazine; Cyanides; Depression, Chemical; Electron Transport; Energy Transfer; Fluorine; Guanidines; Herbicides; Hydrazines; Light; Oxidative Phosphorylation; Phlorhizin; Plants; Quinacrine; Tyrothricin | 1969 |
Inhibitors and uncouplers of photophosphorylation.
Topics: Adenosine Triphosphate; Antimetabolites; Benzoates; Chloroplasts; Chlorpromazine; Cyanides; Electron Transport; Ferrocyanides; Guanidines; In Vitro Techniques; Light; Phenazines; Phosphates; Quinacrine; Tyrothricin | 1965 |
Ion and water transport processes in spinach chloroplasts.
Topics: Adenosine Triphosphate; Chlorophyll; Chloroplasts; Chlorpromazine; Cytochromes; Electron Transport; Energy Transfer; Hydrogen-Ion Concentration; Osmosis; Oxidation-Reduction; Oxidative Phosphorylation; Photosynthesis; Plants, Edible; Quinacrine | 1966 |
[Experience with the use of acrichine in patients in depressive states and catatonis(preliminary report)].
Topics: Adjustment Disorders; Adolescent; Adult; Antidepressive Agents; Bipolar Disorder; Catatonia; Chlorpromazine; Depression; Female; Hallucinations; Humans; Imipramine; Male; Middle Aged; Quinacrine | 1966 |
Lanthanum chloride inhibition of the secretory response to Escherichia coli heat-stable enterotoxin.
Topics: Animals; Chlorpromazine; Cyclic GMP; Enterotoxins; Enzyme Activation; Escherichia coli; Guanylate Cyclase; Intestinal Mucosa; Lanthanum; Mice; Quinacrine | 1982 |
Quinacrine mustard inactivates the bovine heart mitochondrial F1-ATPase with the modification of the beta subunit.
Topics: Adenosine Triphosphate; Animals; Cattle; Chlorpromazine; Kinetics; Macromolecular Substances; Magnesium; Mitochondria, Heart; Proton-Translocating ATPases; Quinacrine; Quinacrine Mustard | 1983 |
Effects of phospholipase A2 inhibitors on diethyl maleate-induced lipid peroxidation and cellular injury in isolated rat hepatocytes.
Topics: Animals; Aspirin; Bucladesine; Chlorpromazine; Dexamethasone; Glutathione; In Vitro Techniques; L-Lactate Dehydrogenase; Lipid Peroxides; Liver; Male; Maleates; Phospholipases; Phospholipases A; Phospholipases A2; Quinacrine; Rats | 1982 |
Effects of amphipathic drugs on L'[3H]glutamate binding to synaptic membranes and the purified binding protein.
Topics: Anesthetics, Local; Animals; Chlorpromazine; Dibucaine; Glutamates; Kinetics; Male; Quinacrine; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Glutamate; Synaptic Membranes; Tetracaine | 1984 |
Arachidonate metabolism, 5-hydroxytryptamine release and aggregation in human platelets activated by palmitaldehyde acetal phosphatidic acid.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Chlorpromazine; Humans; In Vitro Techniques; Indomethacin; Lipids; Malondialdehyde; Platelet Aggregation; Platelet Count; Quinacrine; Serotonin; Thionucleotides; Thrombin | 1984 |
Improvement of the anoxia-induced mitochondrial dysfunction by membrane modulation.
Topics: Acetophenones; Adenine Nucleotides; Alkaloids; Animals; Benzylisoquinolines; Chlorpromazine; Egtazic Acid; Hypoxia; Kinetics; Male; Mitochondria, Liver; Mitochondrial Swelling; Oxidative Phosphorylation; Oxygen Consumption; Phospholipids; Quinacrine; Rats; Rats, Inbred Strains | 1984 |
Inhibition of lipid peroxidation in muscle homogenates by phospholipase A2 inhibitors.
Topics: Animals; Chloroquine; Chlorpromazine; Dibucaine; Female; Free Radicals; In Vitro Techniques; Iron; Lipid Peroxides; Mice; Muscles; Phospholipases; Phospholipases A; Phospholipases A2; Procaine; Quinacrine; Tetracaine | 1984 |
Effects of several inhibitors on the K+ efflux induced by activation of the Ca2+-dependent channel and by valinomycin in the human red cell.
Topics: Antimycin A; Calcimycin; Chlorides; Chlorpromazine; Dipyridamole; Erythrocytes; Humans; Ion Channels; Oligomycins; Potassium; Propranolol; Quinacrine; Sodium; Valinomycin | 1980 |
Differential effects of calmodulin antagonists on phospholipases A2 and C in thrombin-stimulated platelets.
Topics: Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium-Binding Proteins; Calmodulin; Chlorpromazine; Dibucaine; Fluphenazine; Humans; Kinetics; Phospholipases; Phospholipases A; Phospholipids; Platelet Aggregation; Quinacrine; Thrombin; Trifluoperazine; Type C Phospholipases | 1981 |
Acetal phosphatidic acids: novel platelet aggregating agents.
Topics: Adenosine Diphosphate; Animals; Aspirin; Chlorpromazine; Drug Interactions; Humans; In Vitro Techniques; Phosphatidic Acids; Platelet Aggregation; Quinacrine; Sheep; Species Specificity | 1983 |
Inhibitors of 125I-epidermal growth factor internalization.
Topics: Acetophenones; Animals; Azo Compounds; Bacitracin; Cells, Cultured; Chlorpromazine; Endocytosis; Epidermal Growth Factor; Methylamines; Peptides; Phenylglyoxal; Phospholipases; Phospholipases A; Quinacrine; Rats | 1980 |
The uptake of 14C-chloroquine by mouse pancreatic islets in vitro.
Topics: Absorption; Animals; Chloroquine; Chlorpromazine; Desipramine; Glucose; Hydrogen-Ion Concentration; Imipramine; Islets of Langerhans; Lidocaine; Mice; Nicotine; Nitrogen; Ouabain; Quinacrine; Temperature | 1980 |
Inhibition of the energy-linked fluorescence response of quinacrine with local anesthetics.
Topics: Anesthetics, Local; Animals; Cattle; Chlorpromazine; Kinetics; Mitochondria; Mitochondria, Heart; Multienzyme Complexes; NADH, NADPH Oxidoreductases; Quinacrine; Spectrometry, Fluorescence; Submitochondrial Particles | 1982 |
Biphasic actions of chlorpromazine and mepacrine on modulation of hepatic cell injury in the perfused cat liver.
Topics: Amines; Animals; Cathepsin D; Cathepsins; Cats; Chemical and Drug Induced Liver Injury; Chlorpromazine; Female; Hypoxia; In Vitro Techniques; L-Lactate Dehydrogenase; Lysosomes; Male; Quinacrine; Time Factors | 1981 |
Quinacrine mustard and lipophilic cations inhibitory to both vacuolar H(+)-ATPase and F0F1-ATP synthase.
Topics: Amino Acid Sequence; Animals; Binding, Competitive; Brain; Cations; Cattle; Chlorpromazine; Chromaffin Granules; Dequalinium; Dithiothreitol; Escherichia coli; Molecular Sequence Data; Plants; Proton-Translocating ATPases; Quinacrine; Quinacrine Mustard; Rats; Synaptic Vesicles; Vacuoles | 1995 |
Mutations in the M1 region of the nicotinic acetylcholine receptor alter the sensitivity to inhibition by quinacrine.
Topics: Acetylcholine; Amino Acid Sequence; Amino Acids; Animals; Bungarotoxins; Chlorpromazine; Enzyme Inhibitors; Hydrogen-Ion Concentration; Molecular Sequence Data; Mutagenesis, Site-Directed; Nicotinic Antagonists; Quinacrine; Receptors, Nicotinic; Sensitivity and Specificity; Torpedo | 1995 |
Ca2+-calmodulin antagonists interfere with xylanase formation and secretion in Trichoderma reesei.
Topics: Calcimycin; Calcium; Calmodulin; Chelating Agents; Chlorpromazine; Egtazic Acid; Ionophores; Lanthanum; Protein Kinases; Quinacrine; Subcellular Fractions; Transcription, Genetic; Trichoderma; Trifluoperazine; Xylan Endo-1,3-beta-Xylosidase; Xylosidases | 1998 |
Acridine and phenothiazine derivatives as pharmacotherapeutics for prion disease.
Topics: Acridines; Animals; Cells, Cultured; Chlorpromazine; Fatty Acids; Humans; Mice; Neuroblastoma; Phenothiazines; Prion Diseases; Protein Conformation; PrPSc Proteins; Quinacrine; Safety; Structure-Activity Relationship; Time Factors; Tumor Cells, Cultured | 2001 |
Old drugs to treat new variant Creutzfeldt-Jakob disease.
Topics: Animals; Antimalarials; Antipsychotic Agents; Chlorpromazine; Creutzfeldt-Jakob Syndrome; Drug Therapy, Combination; Humans; Mice; Prion Diseases; Quinacrine; Tumor Cells, Cultured | 2001 |
Drugs for malaria and psychosis may offer hope to people with CJD.
Topics: Adult; Antimalarials; Antipsychotic Agents; Chlorpromazine; Creutzfeldt-Jakob Syndrome; Female; Humans; Quinacrine | 2001 |
Evaluation of quinacrine treatment for prion diseases.
Topics: Animals; Chlorpromazine; Cricetinae; Drug Resistance; Endopeptidase K; Humans; Melatonin; Mice; Mice, Inbred C57BL; Peptides; Prion Diseases; Prions; PrPC Proteins; PrPSc Proteins; Quinacrine; Tumor Cells, Cultured | 2003 |
The effects of atebrin and chlorpromazine on some adenosine triphosphate-splitting enzymes.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Chlorpromazine; Quinacrine | 1959 |
[DRUGS FOR TREATING ARRHYTHMIA].
Topics: Arrhythmias, Cardiac; Chlorpromazine; Digitalis Glycosides; Humans; Pharmacology; Potassium; Procainamide; Quinacrine; Quinidine; Reserpine | 1963 |
APLASTIC VERSUS HYPERPLASTIC BLOOD DYSCRASIAS.
Topics: Anemia; Anemia, Aplastic; Anti-Bacterial Agents; Benzene; Bone Marrow Diseases; Chlorpromazine; Cobalt; DDT; Folic Acid Antagonists; Hematology; Humans; Iatrogenic Disease; Leukemia; Nitrogen Mustard Compounds; Nitrous Oxide; Phenylbutazone; Phenytoin; Promazine; Quinacrine; Sulfonamides; Thiouracil; Toxicology; Trinitrotoluene; Vitamins | 1964 |
PARTICIPATION OF FLAVIN DERIVATIVES IN ADENOSINE TRIPHOSPHATASE REACTIONS OF STRIATED MUSCLE.
Topics: Adenosine Triphosphatases; Chlorpromazine; Cyanides; Dinitrophenols; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Mitochondria; Muscle Proteins; Muscle, Striated; Muscles; Pharmacology; Quinacrine; Research | 1964 |
THE RESPIRATORY ACTIVITY OF ISOLATED MAMMALIAN NUCLEI. II. THE NADH OXIDASE OF RAT LIVER NUCLEOLI.
Topics: Animals; Cell Nucleus; Chlorpromazine; Cyanides; Cytochromes; Electron Transport; Liver; Metabolism; Multienzyme Complexes; NADH, NADPH Oxidoreductases; Oxidoreductases; Quinacrine; Rats; Research; Spectrum Analysis | 1964 |
CHANGES EFFECTED IN VITRO UPON SOME MORPHOLOGICAL PROPERTIES OF PARTICLES OF VIRUS BAI-STRAIN A.
Topics: Adenine Nucleotides; Animals; Benzoates; Borates; Chloromercuribenzoates; Chlorpromazine; Ethylmaleimide; In Vitro Techniques; Iodoacetates; Pharmacology; Pyrroles; Quinacrine; Research; Tromethamine; Vertebrates; Viruses | 1965 |
[RESPIRATION OF YEAST FOAM IN THE PRESENCE OF LARGACTIL, ATABRINE AND 3-AMINO-1,2,4-TRIAZOLE].
Topics: Amitrole; Chlorpromazine; Fungi; Quinacrine; Research; Triazoles; Yeasts | 1964 |
Compassionate use of quinacrine in Creutzfeldt-Jakob disease fails to show significant effects.
Topics: Adult; Brain; Chlorpromazine; Creutzfeldt-Jakob Syndrome; DNA Mutational Analysis; Dopamine Antagonists; Drug Therapy, Combination; Enzyme Inhibitors; Female; Humans; Insomnia, Fatal Familial; Male; Middle Aged; Mutation; Quinacrine; Treatment Failure | 2005 |
Creutzfeldt-Jakob disease acquired via a dural graft: failure of therapy with quinacrine and chlorpromazine.
Topics: Adult; Arnold-Chiari Malformation; Cadaver; Chlorpromazine; Creutzfeldt-Jakob Syndrome; Dopamine Antagonists; Drug Resistance; Dura Mater; Enzyme Inhibitors; Fatal Outcome; Female; Humans; Iatrogenic Disease; Middle Aged; Quinacrine; Risk Factors; Time Factors | 2005 |
Inhibition of RNA recruitment and replication of an RNA virus by acridine derivatives with known anti-prion activities.
Topics: Acridines; Antiviral Agents; Chemistry, Pharmaceutical; Chlorpromazine; Drug Design; Models, Genetic; Plant Viruses; Prion Diseases; Prions; Quinacrine; RNA; RNA Viruses; Tombusvirus; Viral Proteins; Virus Replication | 2009 |
Synthesis of conjugates of 6-aminophenanthridine and guanabenz, two structurally unrelated prion inhibitors, for the determination of their cellular targets by affinity chromatography.
Topics: Binding, Competitive; Chlorpromazine; Chromatography, Affinity; Guanabenz; Microspheres; Phenanthridines; Prions; Quinacrine; Ribosomes; RNA, Ribosomal; Sepharose | 2010 |