chlorpromazine and pyrilamine

chlorpromazine has been researched along with pyrilamine in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199012 (52.17)18.7374
1990's0 (0.00)18.2507
2000's6 (26.09)29.6817
2010's4 (17.39)24.3611
2020's1 (4.35)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Andrews, PR; Craik, DJ; Martin, JL1
Strassburg, CP; Tukey, RH1
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B1
Caron, G; Ermondi, G1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Ahman, M; Holmén, AG; Wan, H1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Bienkowski, P; Bucki, A; Jaśkowska, J; Kazek, G; Kowalski, P; Kołaczkowski, M; Marcinkowska, M; Mierzejewski, P; Mitka, K; Pawłowski, M; Siwek, A; Wasik, A; Wesołowska, A1
Bienkowski, P; Bucki, A; Jastrzębska-Więsek, M; Kazek, G; Kołaczkowski, M; Marcinkowska, M; Mierzejewski, P; Partyka, A; Pawłowski, M; Siwek, A; Śniecikowska, J; Wasik, A; Wesołowska, A1
Bucki, A; Głuch-Lutwin, M; Jakubczyk, M; Jamrozik, M; Jastrzębska-Więsek, M; Kołaczkowski, M; Marcinkowska, M; Mierzejewski, P; Partyka, A; Pawłowski, M; Pytka, K; Siwek, A; Śniecikowska, J; Wesołowska, A; Zagórska, A1
Allan, D; Brindley, DN; Michell, RH1
Gárdos, G; Lassen, UV; Pape, L1
Czerwińska, U; Kazimierczak, W; Maśliński, C; Wyczólkowska, J1
Bowley, M; Brindley, DN1
Ishigooka, J; Miura, S; Shizu, Y; Tanaka, K; Wakatabe, H1
Ieni, JR; Meyerson, LR; Wennogle, LP1
Attwood, D; Natarajan, R1
Wallace, RM; Young, JM1
Basta-Kaim, A; Budziszewska, B; Jaworska-Feil, L; Kubera, M; Lasoń, W; Leśkiewicz, M; Tetich, M1
BETTINI, S; CANTORE, G1
HALPERN, BN; NEVEU, T; SPECTOR, S1

Reviews

1 review(s) available for chlorpromazine and pyrilamine

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000

Other Studies

22 other study(ies) available for chlorpromazine and pyrilamine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
    Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11

    Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Novel arylsulfonamide derivatives with 5-HT₆/5-HT₇ receptor antagonism targeting behavioral and psychological symptoms of dementia.
    Journal of medicinal chemistry, 2014, Jun-12, Volume: 57, Issue:11

    Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Avoidance Learning; Benzoxazoles; Catalepsy; CHO Cells; Cricetulus; Dementia; Dopamine D2 Receptor Antagonists; HEK293 Cells; Humans; Male; Models, Molecular; Motor Activity; Radioligand Assay; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Sulfonamides

2014
Novel 5-HT6 receptor antagonists/D2 receptor partial agonists targeting behavioral and psychological symptoms of dementia.
    European journal of medicinal chemistry, 2015, Mar-06, Volume: 92

    Topics: Animals; Benzamides; Dementia; Dose-Response Relationship, Drug; Drug Partial Agonism; Humans; Indoles; Ligands; Male; Models, Molecular; Molecular Structure; Piperazines; Quinolones; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Serotonin; Structure-Activity Relationship; Swimming

2015
Multifunctional 6-fluoro-3-[3-(pyrrolidin-1-yl)propyl]-1,2-benzoxazoles targeting behavioral and psychological symptoms of dementia (BPSD).
    European journal of medicinal chemistry, 2020, Apr-01, Volume: 191

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Benzoxazoles; Dementia; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ether-A-Go-Go Potassium Channels; Humans; Male; Mice; Models, Molecular; Molecular Structure; Structure-Activity Relationship

2020
Letter: The redirection of glyceride and phospholipid synthesis by drugs including chlorpromazine, fenfluramine, imipramine, mepyramine and local anaesthetics.
    The Journal of pharmacy and pharmacology, 1975, Volume: 27, Issue:6

    Topics: Anesthetics, Local; Animals; Chlorpromazine; Fenfluramine; Glycerides; Imipramine; Lipid Metabolism; Liver; Phospholipids; Phosphoric Monoester Hydrolases; Pyrilamine; Rats

1975
Effect of antihistamines and chlorpromazine on the calcium-induced hyperpolarization of the Amphiuma red cell membrane.
    Biochimica et biophysica acta, 1976, Nov-02, Volume: 448, Issue:4

    Topics: Animals; Biological Transport, Active; Calcimycin; Calcium; Cell Membrane Permeability; Chlorpromazine; Erythrocyte Membrane; Erythrocytes; Histamine; Membrane Potentials; Potassium; Promethazine; Pyridines; Pyrilamine; Urodela

1976
The pharmacological inhibition of the heterologous PCA reaction by histamine antagonists and chloropromazine [proceedings].
    Agents and actions, 1977, Volume: 7, Issue:1

    Topics: Animals; Chlorpromazine; Immune Sera; Immunoglobulin E; Metiamide; Mice; Passive Cutaneous Anaphylaxis; Pyridines; Pyrilamine; Rats; Thiourea

1977
Drugs affecting the synthesis of glycerides and phospholipids in rat liver. The effects of clofibrate, halofenate, fenfluramine, amphetamine, cinchocaine, chlorpromazine, demethylimipramine, mepyramine and some of their derivatives.
    The Biochemical journal, 1975, Volume: 148, Issue:3

    Topics: Amphetamine; Animals; Chlorpromazine; Clofenapate; Clofibrate; Dibucaine; Fenfluramine; Glycerides; Glycerol-3-Phosphate O-Acyltransferase; Halofenate; Imipramine; In Vitro Techniques; Kinetics; Liver; Pharmacology; Phospholipids; Pyrilamine; Rats

1975
Different effects of centrally acting drugs on rabbit platelet aggregation: with special reference to selective inhibitory effects of antipsychotics and antidepressants.
    Biological psychiatry, 1985, Volume: 20, Issue:8

    Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Central Nervous System Agents; Chlorpromazine; In Vitro Techniques; Male; Phenobarbital; Platelet Aggregation; Pyrilamine; Rabbits

1985
Allosteric interaction between the site labeled by [3H]imipramine and the serotonin transporter in human platelets.
    Journal of neurochemistry, 1987, Volume: 48, Issue:2

    Topics: Amitriptyline; Blood Platelets; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorpromazine; Ethylmaleimide; Fluoxetine; Humans; Imipramine; Kinetics; Pyrilamine; Receptors, Serotonin

1987
Effect of pH on the micellar properties of amphiphilic drugs in aqueous solution.
    The Journal of pharmacy and pharmacology, 1981, Volume: 33, Issue:3

    Topics: Chlorpromazine; Colloids; Hydrogen-Ion Concentration; Light; Micelles; Models, Theoretical; Potassium Chloride; Pyrilamine; Scattering, Radiation; Trifluoperazine

1981
Temperature dependence of the binding of [3H]mepyramine and related compounds to the histamine H1 receptor.
    Molecular pharmacology, 1983, Volume: 23, Issue:1

    Topics: Aminopyridines; Animals; Cerebellum; Chlorpromazine; Guinea Pigs; Histamine H1 Antagonists; Kinetics; Male; Phenothiazines; Promethazine; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Temperature; Tripelennamine

1983
Chlorpromazine inhibits the glucocorticoid receptor-mediated gene transcription in a calcium-dependent manner.
    Neuropharmacology, 2002, Volume: 43, Issue:6

    Topics: Animals; Antipsychotic Agents; Calcimycin; Calcium; Calcium Channel Blockers; Cell Line; Cell Line, Transformed; Chloramphenicol O-Acetyltransferase; Chlorpromazine; Clozapine; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Estrenes; Fibroblasts; Gene Expression Regulation; Genes, Reporter; Haloperidol; Histamine; Histamine H1 Antagonists; Ionophores; Mammary Tumor Virus, Mouse; Mice; Nifedipine; Phorbol Esters; Phosphodiesterase Inhibitors; Protein Kinase C; Protein Kinase C-alpha; Pyrilamine; Pyrrolidinones; Raclopride; Receptors, Glucocorticoid; Remoxipride; Sulfonamides; Sulpiride; Tetradecanoylphorbol Acetate; Thionucleotides; Transcription, Genetic; Type C Phospholipases

2002
[Protective action of ACTH, cortisone, calcium gluconate, pyrilamine (neoantergan), promethazine (fargan), and chlorpromazine (largactil) against experimental poisoning with Latrodectus venom in guinea pigs].
    Rendiconti - Istituto superiore di sanita, 1955, Volume: 18, Issue:6

    Topics: Adrenocorticotropic Hormone; Antipsychotic Agents; Calcium Gluconate; Chlorpromazine; Cortisone; Gluconates; Guinea Pigs; Phenothiazines; Poisoning; Promethazine; Pyrilamine; Venoms

1955
On the nature of the chemical mediators involved in anaphylactic reactions in mice.
    British journal of pharmacology and chemotherapy, 1963, Volume: 20

    Topics: Anaphylaxis; Animals; Anti-Allergic Agents; Capillary Permeability; Chlorpromazine; Histamine; Histamine H1 Antagonists; Lysergic Acid Diethylamide; Mice; Passive Cutaneous Anaphylaxis; Promethazine; Pyrilamine; Serotonin

1963