chlorpromazine and propylthiouracil

chlorpromazine has been researched along with propylthiouracil in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19905 (27.78)18.7374
1990's2 (11.11)18.2507
2000's4 (22.22)29.6817
2010's7 (38.89)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Hamatani, Y; Inoue, M; Kimura, K; Ohta, M; Shiota, M; Sugano, T1
Linares Rodríguez, A; Recarte Alvarez, J; Rodrigo Sáez, L; Valerdiz Casasola, S1
Jiang, X; Khursigara, G; Rubin, RL1
FISCHER, R; GRIFFIN, F1
LURIE, E; PRUSAK, Y1
FISCHETTI, B1
BIZZI, A; CODEGONI, AM; GARATTINI, S1

Reviews

2 review(s) available for chlorpromazine and propylthiouracil

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Hepatitis caused by drugs. 5].
    Revista espanola de las enfermedades del aparato digestivo, 1982, Volume: 62, Issue:5

    Topics: Chemical and Drug Induced Liver Injury; Chlorpromazine; Deoxyepinephrine; Erythromycin; Gold; Humans; Hypoglycemic Agents; Oxacillin; Oxyphenisatin Acetate; Perhexiline; Phenylbutazone; Prognosis; Propylthiouracil

1982

Other Studies

16 other study(ies) available for chlorpromazine and propylthiouracil

ArticleYear
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Effects of calmodulin antagonists on hydrogen-translocating shuttles in perfused rat liver.
    The American journal of physiology, 1991, Volume: 261, Issue:3 Pt 1

    Topics: Adrenalectomy; Alanine; Aminooxyacetic Acid; Animals; Asparagine; Calcium; Calmodulin; Chlorpromazine; Glycerolphosphate Dehydrogenase; Hyperthyroidism; Hypothyroidism; Liver; Male; Mitochondria, Liver; NAD; Oxidation-Reduction; Perfusion; Propylthiouracil; Rats; Rats, Inbred Strains; Reference Values; Sorbitol; Sulfonamides; Thyroxine; Trifluoperazine; Triiodothyronine; Vasopressins

1991
Transformation of lupus-inducing drugs to cytotoxic products by activated neutrophils.
    Science (New York, N.Y.), 1994, Nov-04, Volume: 266, Issue:5186

    Topics: Animals; Biological Assay; Biotransformation; Cell Death; Chlorpromazine; Humans; Hydralazine; Hydrogen Peroxide; Isoniazid; Lupus Erythematosus, Systemic; Mice; Neutrophil Activation; Neutrophils; Peroxidase; Procainamide; Propylthiouracil; Quinidine; Tumor Cells, Cultured

1994
QUININE DIMORPHISM: A CARDINAL DETERMINANT OF TASTE SENSITIVITY.
    Nature, 1963, Oct-26, Volume: 200

    Topics: Acetates; Adolescent; Amides; Amphetamine; Amphetamines; Antithyroid Agents; Child; Chlorpromazine; Dextroamphetamine; Ergothioneine; Genetics, Medical; Humans; Imipramine; Methylene Blue; Pharmacology; Phenylalanine; Physiology; Propylthiouracil; Quinine; Sex; Sodium Chloride; Sucrose; Taste; Thioridazine; Triflupromazine; Urea

1963
[DRUG-INDUCED AGRANULOCYTOSIS].
    Harefuah, 1964, Jul-01, Volume: 67

    Topics: Agranulocytosis; Aminopyrine; Chloramphenicol; Chlorpromazine; Diuretics; Humans; Organomercury Compounds; Propylthiouracil; Quinolines; Sulfanilamide; Sulfanilamides; Sulfonamides; Toxicology

1964
[EXPERIMENTAL CONTRIBUTION TO THE STUDY OF THE MECHANISM OF THYROID ACTION OF VARIOUS PSYCHOACTIVE DRUGS. RESEARCH CONDUCTED ON THYROID IODINE UPTAKE IN VITRO].
    Archivio italiano di scienze farmacologiche, 1963, Volume: 13

    Topics: Animals; Chlorpromazine; Imipramine; In Vitro Techniques; Iodine; Iodine Isotopes; Perphenazine; Pharmacology; Propylthiouracil; Psychotropic Drugs; Research; Swine; Thyroid Function Tests; Thyroid Gland; Triflupromazine

1963
SALICYLATE, A POWERFUL INHIBITOR OF FREE FATTY ACID RELEASE.
    Nature, 1964, Dec-19, Volume: 204

    Topics: Adipose Tissue; Adrenalectomy; Adrenocorticotropic Hormone; Antimetabolites; Aspirin; Benzoates; Chlorpromazine; Cold Temperature; Fasting; Fatty Acids; Fatty Acids, Nonesterified; Lipid Metabolism; Norepinephrine; Pharmacology; Propylthiouracil; Rats; Research; Salicylates; Sodium Salicylate

1964