chlorpromazine and primidone

chlorpromazine has been researched along with primidone in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199016 (64.00)18.7374
1990's0 (0.00)18.2507
2000's2 (8.00)29.6817
2010's7 (28.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Andricopulo, AD; Moda, TL; Montanari, CA1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Monroe, RR1
Kutt, H; Penry, JK1
Afifi, AK; Van Allen, MW1
Millichap, JG1
Norton, PR1
Mandel, HG; Riis, M1
Grinberg, KN; Shapiro, IuL; Vaĭntrub, MIa; Zhurkov, VS1
Trautmann, A1
Jenny, E; Solberg, R1
Olesen, OV1
RETTIG, JH1
ARORA, RB; SHARMA, PL1
HABOVICK, JA; MCCABE, WS1
MEYER, HJ; MEYER-BURG, J1
LORGE, M1
MOROZ, R; RECHTER, E1

Reviews

3 review(s) available for chlorpromazine and primidone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Usefulness of blood levels of antiepileptic drugs.
    Archives of neurology, 1974, Volume: 31, Issue:5

    Topics: Anticonvulsants; Carbamazepine; Chloramphenicol; Chlordiazepoxide; Chlorpromazine; Chromatography, Gas; Dextropropoxyphene; Diazepam; Dicumarol; Disulfiram; Drug Interactions; Epilepsy; Ethosuximide; Humans; Isoniazid; Methylphenidate; Phenethylamines; Phenobarbital; Phenylbutazone; Phenytoin; Primidone; Prochlorperazine; Sulfamethizole; Sulfaphenazole; Thiazines

1974
[Teratogenic and mutagenic effects of anticonvulsive and psychotropic drugs (review of the literature)].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1972, Volume: 72, Issue:6

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Anticonvulsants; Antidepressive Agents; Arm; Barbiturates; Chlorpromazine; Chromosome Aberrations; Chromosome Disorders; Cricetinae; Drosophila; Female; Heart Defects, Congenital; Humans; Imipramine; Infant, Newborn; Jaundice, Neonatal; Mutagens; Perphenazine; Phenothiazines; Phenytoin; Pregnancy; Primidone; Rabbits; Thalidomide; Tranquilizing Agents; Trifluoperazine

1972

Trials

1 trial(s) available for chlorpromazine and primidone

ArticleYear
Anticonvulsants in the treatment of aggression.
    The Journal of nervous and mental disease, 1975, Volume: 160, Issue:2-1

    Topics: Adult; Aggression; Anticonvulsants; Chlordiazepoxide; Chlorpromazine; Drug Therapy, Combination; Epilepsy; Humans; Impulsive Behavior; Male; Mental Disorders; Neurocognitive Disorders; Phenytoin; Primidone; Schizophrenia; Trifluoperazine; Violence

1975

Other Studies

21 other study(ies) available for chlorpromazine and primidone

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Cerebellar atrophy in epilepsy. Pneumographic and histological documentation of a case with psychosis.
    Journal of neurology, neurosurgery, and psychiatry, 1968, Volume: 31, Issue:2

    Topics: Adult; Brain; Cerebellar Ataxia; Cerebral Ventriculography; Chlorpromazine; Diplopia; Electroconvulsive Therapy; Electroencephalography; Epilepsy, Tonic-Clonic; Facial Muscles; Female; Gait; Humans; Hydantoins; Intellectual Disability; Neurocognitive Disorders; Nystagmus, Pathologic; Phenytoin; Primidone; Psychological Tests; Purkinje Cells; Schizophrenia; Staining and Labeling

1968
Drugs in management of hyperkinetic and perceptually handicapped children.
    JAMA, 1968, Nov-11, Volume: 206, Issue:7

    Topics: Anticonvulsants; Central Nervous System Stimulants; Child; Child, Preschool; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Epilepsy; Humans; Hyperkinesis; Methylphenidate; Perceptual Disorders; Phenytoin; Primidone; Psychological Tests; Seizures; Tranquilizing Agents

1968
The effects of drugs on barbiturate withdrawal convulsions in the rat.
    The Journal of pharmacy and pharmacology, 1970, Volume: 22, Issue:10

    Topics: Animals; Barbiturates; Chlordiazepoxide; Chlorpromazine; Ethanol; Ethosuximide; Female; Humans; Hydrazines; Hypnotics and Sedatives; Meprobamate; Methyltyrosines; Monoamine Oxidase Inhibitors; Morphine; Phenylalanine; Primidone; Rats; Reserpine; Seizures; Serotonin; Substance Withdrawal Syndrome; Tryptophan

1970
Interference of barbiturates with pyrimidine incorporation. II. Structural specificity of the inhibition of orotate uptake in Bacillus cereus.
    Biochemical pharmacology, 1970, Volume: 19, Issue:6

    Topics: Amobarbital; Bacillus cereus; Barbiturates; Bemegride; Biological Transport; Carbon Isotopes; Carboxylic Acids; Central Nervous System Stimulants; Chemical Phenomena; Chemistry; Chemistry, Physical; Chlorine; Chlorpromazine; Glutethimide; Hexobarbital; Hydantoins; Hydrocarbons, Halogenated; Hydrogen-Ion Concentration; Orotic Acid; Pentobarbital; Phenobarbital; Phenytoin; Primidone; Solubility; Succinimides; Thiopental; Thymine; Trimethadione; Tromethamine; Uracil; Urea

1970
[Dialysis of drugs and poisons. 2].
    Medizinische Klinik, 1972, Nov-03, Volume: 67, Issue:44

    Topics: Acetaminophen; Aminopyrine; Amitriptyline; Aspirin; Carbamazepine; Chlordiazepoxide; Chlorpromazine; Dextropropoxyphene; Diazepam; Heroin; Humans; Imipramine; Lithium; Pargyline; Pentazocine; Phenacetin; Phenelzine; Phenytoin; Poisoning; Primidone; Promazine; Renal Dialysis; Salicylates; Tranylcypromine; Trifluoperazine

1972
[Pharmacologic properties of partially purified glutamic acid decarboxylase (L-glutamate-1-carboxylyase, E.C. 4.1.1.15) from calf cerebral cortex].
    Helvetica physiologica et pharmacologica acta, 1968, Volume: 26, Issue:3

    Topics: Animals; Antidepressive Agents; Barbiturates; Carboxy-Lyases; Cattle; Cerebral Cortex; Chemical Phenomena; Chemistry; Chlorpromazine; Codeine; Glutamates; Hydantoins; Imipramine; Lysergic Acid Diethylamide; Phenethylamines; Phenytoin; Primidone; Psilocybin; Pyrrolidines; Spectrophotometry

1968
The influence of disulfiram and calcium carbimide on the serum diphenylhydantoin. Excretion of HPPH in the urine.
    Archives of neurology, 1967, Volume: 16, Issue:6

    Topics: Acetazolamide; Adult; Aged; Alcoholism; Amitriptyline; Chlordiazepoxide; Chlorpromazine; Chromatography, Thin Layer; Cyanates; Disulfiram; Drug Synergism; Epilepsy; Humans; Hydroflumethiazide; Imipramine; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone

1967
Chlorpromazine and mysoline in the control of convulsive epilepsy in mentally deficient patients.
    The Journal of nervous and mental disease, 1956, Volume: 124, Issue:6

    Topics: Chlorpromazine; Epilepsy; Humans; Intellectual Disability; Primidone

1956
Effectiveness of some anticonvulsant drugs in ventricular tachycardia resulting from acute myocardial infarction in the dog.
    The Indian journal of medical research, 1958, Volume: 46, Issue:6

    Topics: Acetazolamide; Animals; Anticonvulsants; Chlorpromazine; Dogs; Humans; Myocardial Infarction; Primidone; Tachycardia; Tachycardia, Ventricular; Tranquilizing Agents

1958
THORAZINE AS AN EPILEPTOGENIC AGENT.
    The American journal of psychiatry, 1963, Volume: 120

    Topics: Chlorpromazine; Epilepsy; Humans; Pharmacology; Phenytoin; Primidone; Schizophrenia

1963
[INHIBITION OF ELECTROCONVULSION BY THE KAVA-PYRONES DIHYDROMETHYSTICIN AND DIHYDROKAVAIN].
    Archives internationales de pharmacodynamie et de therapie, 1964, Mar-01, Volume: 148

    Topics: Anticonvulsants; Chlorpromazine; Kava; Mice; Pharmacology; Phenobarbital; Phenytoin; Primidone; Pyrones; Rats; Research; Seizures

1964
[THE PROSTRATION SYNDROME. SERIOUS DANGER OF DRUG THERAPY IN EPILEPSY].
    Deutsche medizinische Wochenschrift (1946), 1964, Sep-04, Volume: 89

    Topics: Adolescent; Anticonvulsants; Chlorpromazine; Down Syndrome; Drug Therapy; Electroencephalography; Epilepsy; Epilepsy, Tonic-Clonic; Hydantoins; Phenobarbital; Primidone; Seizures; Toxicology

1964
MANAGEMENT OF PATIENTS WITH IMPENDING AND FULL-BLOWN DELIRIUM TREMENS.
    The Psychiatric quarterly, 1964, Volume: 38

    Topics: Adrenocorticotropic Hormone; Alcohol Withdrawal Delirium; Chlordiazepoxide; Chlorpromazine; Drug Therapy; Humans; Magnesium; Mental Disorders; Meprobamate; Mortality; Primidone; Promazine; Psychoses, Alcoholic; Psychotic Disorders; Vitamin B 12; Water-Electrolyte Balance

1964