chlorpromazine and practolol

chlorpromazine has been researched along with practolol in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19909 (50.00)18.7374
1990's0 (0.00)18.2507
2000's5 (27.78)29.6817
2010's4 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA1
Caron, G; Ermondi, G1
Abraham, MH; Acree, WE; Ibrahim, A1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Lee, AG1
Ramasarma, T; Sitaramam, V1
Boucher, SD; Katz, NL1
Lalaian, AA1
Crews, SJ1
Maas, D; Schubothe, H1
Speiser, Z; Weinstock, M1
Clarke, IM; Ellis, FR1

Other Studies

18 other study(ies) available for chlorpromazine and practolol

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Rational use of in vitro P-glycoprotein assays in drug discovery.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera

2001
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:3

    Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Local anesthesia: the interaction between phospholipids and chlorpromazine, propranolol, and practolol.
    Molecular pharmacology, 1977, Volume: 13, Issue:3

    Topics: Anesthetics, Local; Chemical Phenomena; Chemistry; Chlorpromazine; Hydrogen-Ion Concentration; Liposomes; Membrane Lipids; Membranes, Artificial; Phosphatidic Acids; Phosphatidylethanolamines; Practolol; Propranolol; Pulmonary Surfactants; Temperature; Thermodynamics

1977
Inhibitory action of norepinephrine on the induction of tryptophan-2,3-dioxygenase by cortisol: mediation by the alpha-receptor.
    Life sciences, 1975, May-01, Volume: 16, Issue:9

    Topics: Adrenal Glands; Adrenalectomy; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Chlorpromazine; Corticosterone; Enzyme Induction; Hydrocortisone; Liver; Male; Norepinephrine; Phenoxybenzamine; Phentolamine; Practolol; Propranolol; Rats; Receptors, Adrenergic; Tryptophan Oxygenase

1975
Effects of several 'membrane stabilizing' agents on frog neuromuscular junction.
    European journal of pharmacology, 1977, Mar-21, Volume: 42, Issue:2

    Topics: Animals; Anura; Chlorpromazine; Haloperidol; In Vitro Techniques; Membrane Potentials; Methoxyflurane; Motor Endplate; Neuromuscular Junction; Practolol; Rana pipiens; Strychnine; Time Factors; Vinblastine

1977
[Erythrocyte electrolyte concentration in the presence of hyperadrenalinemia and exposure to several adrenolytic substances].
    Zhurnal eksperimental'noi i klinicheskoi meditsiny, 1977, Volume: 17, Issue:4

    Topics: Animals; Chlorpromazine; Epinephrine; Erythrocytes; Potassium; Practolol; Rabbits; Sodium

1977
Ocular adverse reactions to drugs.
    The Practitioner, 1977, Volume: 219, Issue:1309

    Topics: Adrenal Cortex Hormones; Adult; Aged; Amblyopia; Cataract; Chloroquine; Chlorpromazine; Conjunctivitis; Corneal Diseases; Drug Hypersensitivity; Eye Diseases; Glaucoma; Humans; Middle Aged; Practolol

1977
[Drug-induced systemic lupus erythematosus (author's transl)].
    Immunitat und Infektion, 1977, Volume: 5, Issue:4

    Topics: Adolescent; Aged; Anti-Bacterial Agents; Antibody Formation; Autoantibodies; Child; Chlorpromazine; Female; Humans; Hydralazine; Immune Tolerance; Lupus Erythematosus, Systemic; Methyldopa; Practolol; Procainamide

1977
Modification by propranolol and related compounds of motor activity and stereotype behaviour induced in the rat by amphetamine.
    European journal of pharmacology, 1974, Volume: 25, Issue:1

    Topics: Amphetamine; Animals; Behavior; Chlorpromazine; Dose-Response Relationship, Drug; Humans; Male; Motor Activity; Moxisylyte; Norepinephrine; Oxprenolol; Practolol; Propranolol; Rats; Spiperone; Stereotyped Behavior; Stimulation, Chemical

1974
A pack for the emergency treatment of malignant hyperpyrexia.
    Anaesthesia, 1974, Volume: 29, Issue:4

    Topics: Bicarbonates; Chlorpromazine; Dexamethasone; Diazepam; Emergencies; Epinephrine; Equipment and Supplies; Glucose; Humans; Ice; Insulin; Isoproterenol; Malignant Hyperthermia; Practolol; Procaine; Thermometers

1974