chlorpromazine and pirenzepine

chlorpromazine has been researched along with pirenzepine in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19903 (11.11)18.7374
1990's4 (14.81)18.2507
2000's16 (59.26)29.6817
2010's4 (14.81)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Bienkowski, P; Bucki, A; Jaśkowska, J; Kazek, G; Kowalski, P; Kołaczkowski, M; Marcinkowska, M; Mierzejewski, P; Mitka, K; Pawłowski, M; Siwek, A; Wasik, A; Wesołowska, A1
Bienkowski, P; Bucki, A; Jastrzębska-Więsek, M; Kazek, G; Kołaczkowski, M; Marcinkowska, M; Mierzejewski, P; Partyka, A; Pawłowski, M; Siwek, A; Śniecikowska, J; Wasik, A; Wesołowska, A1
Barrantes, MA; Blosser, JC; Manian, AA; McCreedy, SA; Palmer, GC1
Debing, I; Ijzerman, AP; Vauquelin, G1
Chung, C; Cook, P; Pendleton, RG; Risley, E; Williams, M1
Meyer, JM; Simpson, GM1
Bartko, JJ; Conley, RR; Gounaris, C; Hegerty, J; Lingle, J; Love, R; Peszke, M; Richardson, C; Tamminga, CA; Zaremba, S1
De Bittencourt, PR; Hanel, RA; Kranich, M; Sandmann, MC1
Farver, D; Khan, M1
McCallum, SE; Porter, JH; Vann, RE; Varvel, SA1
Kameda, K; Koyama, T; Kusumi, I; Suzuki, K; Takahashi, Y1
Mueser, KT; Noordsy, DL; O'Keefe, C; Xie, H1
Copolov, DL; Dean, B; Hussain, T; Pavey, G; Scarr, E1
Nomikos, GG; Rodriguez, DE; Shirazi-Southall, S1
Dean, B; Parkin, FM; Pavey, G; Scarr, E1
Hägg, S; Hedenmalm, K; Mortimer, O; Spigset, O; Ståhl, M1
Kalkman, HO; Loetscher, E1
Woods, SW1

Reviews

2 review(s) available for chlorpromazine and pirenzepine

ArticleYear
Rapid resolution of antipsychotic-induced tardive dyskinesia with olanzapine.
    South Dakota journal of medicine, 2000, Volume: 53, Issue:2

    Topics: Aged; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Chlorpromazine; Chronic Disease; Dyskinesia, Drug-Induced; Humans; Male; Olanzapine; Pirenzepine; Selective Serotonin Reuptake Inhibitors

2000
Chlorpromazine equivalent doses for the newer atypical antipsychotics.
    The Journal of clinical psychiatry, 2003, Volume: 64, Issue:6

    Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Chlorpromazine; Dibenzothiazepines; Dose-Response Relationship, Drug; Drug Administration Schedule; Haloperidol; Humans; Olanzapine; Piperazines; Pirenzepine; Quetiapine Fumarate; Quinolones; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia; Therapeutic Equivalency; Thiazoles

2003

Trials

2 trial(s) available for chlorpromazine and pirenzepine

ArticleYear
Olanzapine compared with chlorpromazine in treatment-resistant schizophrenia.
    The American journal of psychiatry, 1998, Volume: 155, Issue:7

    Topics: Adult; Akathisia, Drug-Induced; Analysis of Variance; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Brief Psychiatric Rating Scale; Chlorpromazine; Double-Blind Method; Drug Administration Schedule; Female; Haloperidol; Headache; Humans; Male; Olanzapine; Pirenzepine; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Sleep Stages; Treatment Outcome; Xerostomia

1998
Six-month outcomes for patients who switched to olanzapine treatment.
    Psychiatric services (Washington, D.C.), 2001, Volume: 52, Issue:4

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Brief Psychiatric Rating Scale; Chlorpromazine; Dose-Response Relationship, Drug; Female; Humans; Male; Mental Disorders; Middle Aged; Olanzapine; Pirenzepine; Prospective Studies; Severity of Illness Index; Time Factors; Treatment Outcome

2001

Other Studies

23 other study(ies) available for chlorpromazine and pirenzepine

ArticleYear
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
    Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11

    Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Novel arylsulfonamide derivatives with 5-HT₆/5-HT₇ receptor antagonism targeting behavioral and psychological symptoms of dementia.
    Journal of medicinal chemistry, 2014, Jun-12, Volume: 57, Issue:11

    Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Avoidance Learning; Benzoxazoles; Catalepsy; CHO Cells; Cricetulus; Dementia; Dopamine D2 Receptor Antagonists; HEK293 Cells; Humans; Male; Models, Molecular; Motor Activity; Radioligand Assay; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Sulfonamides

2014
Novel 5-HT6 receptor antagonists/D2 receptor partial agonists targeting behavioral and psychological symptoms of dementia.
    European journal of medicinal chemistry, 2015, Mar-06, Volume: 92

    Topics: Animals; Benzamides; Dementia; Dose-Response Relationship, Drug; Drug Partial Agonism; Humans; Indoles; Ligands; Male; Models, Molecular; Molecular Structure; Piperazines; Quinolones; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Serotonin; Structure-Activity Relationship; Swimming

2015
Correlation of activity of chlorpromazine and respective hydroxy, dimethoxy and sulphoxide analogues on dopamine, muscarinic, histamine and calmodulin sites of action.
    Xenobiotica; the fate of foreign compounds in biological systems, 1988, Volume: 18, Issue:3

    Topics: Adenylyl Cyclase Inhibitors; Animals; Binding Sites; Calmodulin; Cerebral Cortex; Chlorpromazine; Cyclic AMP; Dopamine; Histamine; Hypothalamus; Phosphoric Diester Hydrolases; Pirenzepine; Rats; Receptors, Dopamine; Receptors, Muscarinic; Spiperone; Sulfoxides

1988
Melanosome binding and oxidation-reduction properties of synthetic L-dopa-melanin as in vitro tests for drug toxicity.
    Molecular pharmacology, 1988, Volume: 33, Issue:4

    Topics: Animals; Cattle; Chloroquine; Chlorpromazine; Electron Transport; Kinetics; Levodopa; Melanins; Melanocytes; NAD; Oxidation-Reduction; Pirenzepine

1988
Comparison of central gastric antisecretory effects of desmethylimipramine, doxepin and pirenzepine in rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 1984, Volume: 326, Issue:3

    Topics: Animals; Anti-Ulcer Agents; Atropine; Benzodiazepinones; Brain; Chlorpromazine; Desipramine; Doxepin; Gastric Acid; Male; Pirenzepine; Rats; Rats, Inbred Strains

1984
From chlorpromazine to olanzapine: a brief history of antipsychotics.
    Psychiatric services (Washington, D.C.), 1997, Volume: 48, Issue:9

    Topics: Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clozapine; History, 20th Century; Humans; Olanzapine; Pirenzepine; Psychotic Disorders

1997
[Neuroleptic malignant syndrome: case report with recurrence associated with the use of olanzapine].
    Arquivos de neuro-psiquiatria, 1998, Volume: 56, Issue:4

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Haloperidol; Humans; Male; Neuroleptic Malignant Syndrome; Olanzapine; Pirenzepine; Recurrence

1998
Olanzapine. Keep an eye on this neuroleptic.
    Canadian family physician Medecin de famille canadien, 2000, Volume: 46

    Topics: Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clinical Trials as Topic; Dopamine Antagonists; Double-Blind Method; Haloperidol; Humans; Olanzapine; Pirenzepine; Risperidone; Schizophrenia; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists

2000
The discriminative stimulus properties of the atypical antipsychotic olanzapine in rats.
    Psychopharmacology, 2000, Volume: 148, Issue:3

    Topics: Animals; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clozapine; Discrimination Learning; Generalization, Psychological; Haloperidol; Male; Olanzapine; Pirenzepine; Raclopride; Rats; Rats, Sprague-Dawley; Risperidone; Ritanserin; Scopolamine

2000
Differential effects of subchronic treatments with atypical antipsychotic drugs on dopamine D2 and serotonin 5-HT2A receptors in the rat brain.
    Journal of neural transmission (Vienna, Austria : 1996), 2000, Volume: 107, Issue:3

    Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain Chemistry; Chlorpromazine; Dopamine Antagonists; Dose-Response Relationship, Drug; Humans; Indoles; Isoindoles; Male; Olanzapine; Pirenzepine; Protein Binding; Quinolines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Selective Serotonin Reuptake Inhibitors; Thiazoles

2000
Atypical antipsychotic drugs: how much better are they?
    The Harvard mental health letter, 2001, Volume: 17, Issue:10

    Topics: Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clozapine; Haloperidol; Humans; Olanzapine; Pirenzepine

2001
Olanzapine: new preparation. Keep an eye on this neuroleptic.
    Prescrire international, 1999, Volume: 8, Issue:43

    Topics: Antipsychotic Agents; Chlorpromazine; Clinical Trials as Topic; Humans; Pirenzepine; Risperidone; Schizophrenia; Treatment Outcome

1999
Extended treatment with typical and atypical antipsychotic drugs differential effects on the densities of dopamine D2-like and GABAA receptors in rat striatum.
    Life sciences, 2001, Aug-03, Volume: 69, Issue:11

    Topics: Animals; Antipsychotic Agents; Benzamides; Benzazepines; Benzodiazepines; Chlorpromazine; Clozapine; Corpus Striatum; Dose-Response Relationship, Drug; Haloperidol; Male; Muscimol; Olanzapine; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, GABA-A

2001
Effects of typical and atypical antipsychotics and receptor selective compounds on acetylcholine efflux in the hippocampus of the rat.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2002, Volume: 26, Issue:5

    Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clozapine; Dialysis Solutions; Dopamine Antagonists; Extracellular Space; Haloperidol; Hippocampus; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Microdialysis; Olanzapine; Piperazines; Pirenzepine; Rats; Rats, Wistar; Risperidone; Serotonin Antagonists; Thiazoles; Thioridazine

2002
Decreased density of [3H]TCP binding following antipsychotic drug withdrawal in rats.
    Life sciences, 2002, Apr-19, Volume: 70, Issue:22

    Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain; Chlorpromazine; Clozapine; Haloperidol; Ion Channels; Male; Olanzapine; Phencyclidine; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome

2002
Glucose intolerance with atypical antipsychotics.
    Drug safety, 2002, Volume: 25, Issue:15

    Topics: Adverse Drug Reaction Reporting Systems; Antipsychotic Agents; Bayes Theorem; Benzodiazepines; Chlorpromazine; Clozapine; Diabetes Mellitus; Glucose Intolerance; Haloperidol; Humans; Hyperglycemia; Olanzapine; Pirenzepine; Risk Factors; Risperidone; World Health Organization

2002
alpha2C-Adrenoceptor blockade by clozapine and other antipsychotic drugs.
    European journal of pharmacology, 2003, Feb-21, Volume: 462, Issue:1-3

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Brimonidine Tartrate; Chlorpromazine; CHO Cells; Clozapine; Cricetinae; Cyclic AMP; Dibenzothiazepines; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Gene Expression; Haloperidol; Humans; Isoxazoles; Norepinephrine; Olanzapine; Piperazines; Piperidines; Pirenzepine; Quetiapine Fumarate; Quinolones; Quinoxalines; Receptors, Adrenergic, alpha-2; Receptors, Dopamine D2; Risperidone; Thiazoles; Transfection; Yohimbine

2003