chlorpromazine and pimozide

chlorpromazine has been researched along with pimozide in 151 studies

Research

Studies (151)

TimeframeStudies, this research(%)All Research%
pre-1990111 (73.51)18.7374
1990's13 (8.61)18.2507
2000's16 (10.60)29.6817
2010's10 (6.62)24.3611
2020's1 (0.66)2.80

Authors

AuthorsStudies
Ellefson, CR; Kehr, JR; Miller, A; Woo, CM1
Andrieux, M; Besançon, R; Giros, B; Martres, MP; Pilon, C; Schwartz, JC; Sokoloff, P1
Bouthenet, ML; Giros, B; Martres, MP; Schwartz, JC; Sokoloff, P1
Andrews, PR; Craik, DJ; Martin, JL1
Butler, DE; Marriott, JG; Poschel, BP1
Choudhary, MS; Craigo, SC; Meltzer, HY; Monsma, FJ; Roth, BL; Shen, Y; Sibley, DR; Uluer, A1
Emms, F; Freedman, SB; Knowles, MR; Marwood, R; McAllister, G; Patel, S; Seabrook, GR1
Audinot, V; Chaput, C; Conte, C; Gavaudan, S; Millan, MJ; Newman-Tancredi, A; Touzard, M; Verrièle, L1
Topliss, JG; Yoshida, F1
Cavalli, A; De Ponti, F; Poluzzi, E; Recanatini, M1
Ernsberger, P; Hufeisen, SJ; Jayathilake, K; Kroeze, WK; Meltzer, HY; Popadak, BA; Renock, SM; Roth, BL; Steinberg, S1
Glennon, RA1
Keserü, GM1
Li, J; Rajamani, R; Reynolds, CH; Tounge, BA1
Nagashima, R; Nishikawa, T; Tobita, M1
Andricopulo, AD; Moda, TL; Montanari, CA1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Jia, L; Sun, H1
Caron, G; Ermondi, G; Visentin, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Sen, S; Sinha, N1
Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS1
Bellman, K; Knegtel, RM; Settimo, L1
Bennis, K; Ducki, S; Lesage, F; Vivier, D1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Friedman, E; Gershon, S; Rotrosen, J1
Amico, DJ; Calne, DB; Klawans, HL1
Ahlenius, S; Engel, J1
Cuparencu, F; Feszt, G; Kun, I; Orbán, I1
Setler, P; Weidley, E; Zarevics, P1
Lal, S; Tsang, D1
Barreca, T; Gallamini, A; Masturzo, P; Murialdo, G; Rolandi, E1
Munday, KA; Poat, JA; Sumners, C; Woodruff, GN1
Horita, A; Murray, TF1
Desiles, M; Puech, AJ; Rips, R1
Dunlop, RA; Main, CJ; McCreadie, RG1
Jackson, DM1
Fogelholm, R; Kotilainen, P; Lamberg, BA; Linnoila, M; Olkinuora, M; Saarinen, P1
Kuhar, MJ; Rommelspacher, H1
Beaujouan, JC; Glowinski, J; Guyenet, PG; Javory, AF; Rossier, BJ1
Calne, DB; Claveria, LE; Haskayne, L; Lodge-Patch, IC; Pallis, CA; Petrie, A; Teychenne, PF1
Martin, IC1
Kuschinsky, K1
Agid, Y; Beaujouan, JC; Glowinski, J; Guyenet, PG; Javoy, F1
Nose, T; Takemoto, H1
Costa, E; Guidotti, A; Revuelta, A; Zivkovic, B1
Dingell, JV; Hill, H; Robinson, SE; Setler, P; Stawarz, RJ; Sulser, F1
Jones, BE; Risner, ME1
Cookson, JC; Silverstone, T; Wells, B2
Baudry, M; Guyon, A; le Sellin, M; Martres, MP; Morgat, JL; Schwartz, JC1
Cuparencu, B; Feszt, G; Kun, I; Orbán, I1
Cannon, HE; Gillin, JC; Staub, RA; Wyatt, RJ1
Gillin, JC; Moja, EA; Stoff, DM; Wyatt, RJ1
Balakleevskiĭ, AI; Maslova, IV1
Weick, RF1
Cicero, TJ; Fuller, T; Mitchell, MV; Olney, JW; Price, MT1
Anumonye, A; Marinho, AA; Onibuwe-Johnson, T1
Eliasson, M; Meyerson, BJ1
Cuparencu, B; Sandor, V1
Bianchi, S; Consolo, S; Ghezzi, D; Ladinsky, H1
Miller, RJ1
Grandison, L; Meites, J1
Sethy, VH1
Ferko, AP1
Baxter, MG; Miller, AA; Wheatley, PL1
Niemegeers, CJ; Wauquier, A1
Jones, BE; Risner, M1
Fielding, S; Lal, H; Marky, M1
Kelly, PH; Miller, RJ1
Marsden, CD; Pycock, C; Tarsy, D1
Manian, AA; Snyder, SH; Yamamura, HI1
Fillmore, MT; Ruggles, JL; Taukulis, HK1
Nishizawa, S; Peterson, JW; Shimoyama, I; Uemura, K1
Miyamoto, K1
Hall, PF; Papadopoulos, V; Widmaier, EP1
Chen, DL; Gallicchio, VS; Hait, WN; Lazo, JS1
Braun, ID; Hait, WN; Kennedy, KA; Lazo, JS; Meandzija, B1
Brannan, MD; Flaim, SF; Gleason, MM; Muschek, LD; Swigart, SC1
Chihara, K; Fujita, T; Kaji, H; Kita, T; Kodama, H; Minamitani, N1
Crow, TJ; Johnson, AL; Johnstone, EC; MacMillan, JF1
Fujita, M; Horikomi, K1
Hait, WN; Lee, GL1
Coulombe, D; Laviolette, P; Miliaressis, E; Philippe, L; Rompre, PP1
Heyman, GM; Kinzie, DL; Seiden, LS1
Comar, D; Maziere, M; Turner, JH1
Barnes, TR; Katona, CL1
Malmnäs, CO1
Costa, E; Guidotti, A; Zivkovic, B1
Clemens, JA; Sawyer, BD; Smalstig, EB2
Azim, H; Kingstone, E; Kolivakis, T1
Matthysse, S1
Everitt, BJ; Fuxe, K; Hökfelt, T1
Bergmann, F; Chaimovitz, M; Pasternak, V; Ramu, A1
Andén, NE; Bartholini, G; Corrodi, H; Csillik, B; De Robertis, E; Dresse, A; Fuxe, K; Gerebtzoff, MA; Glowinski, J; Hansson, E; Hökfelt, T; Renson, J; Roos, BE1
Willems, JL1
Enero, MA1
Kapturkiewicz, Z; Maj, J; Sarnek, J1
Sethy, VH; Van Woert, MH2
Hatch, RC1
Ritter, S; Stein, L1
Corbin, A; Hollingsworth, DR; Mabry, CC; Upton, GV1
Wurtman, RJ; Yehuda, S1
Breese, GR; Cooper, BR; Grant, LD1
Bartholini, G; Keller, HH; Pletscher, A1
Masur, J; Terada, CW1
Ferrini, R; Miragoli, G1
Duvoisin, RC; Marsden, CD1
Dresse, A; Gérardy, J1
Clemens, JA; Matsumoto, C; Shaar, CJ; Smalstig, EB1
Lee, T; Seeman, P1
Dolphin, A; Duvoisin, RC; Jenner, P; Marsden, CD; Tarsy, D1
Dandiya, PC; Patni, SK1
Michael, RP; Schaefer, GJ1
Cookson, JC1
Alloway, KD; Bashore, TR; Gelman, J; Rebec, GV1
Beal, MF; Martin, JB1
Cheung, CY; Neill, AC; Weiner, RI1
Luchins, DJ; Oliver, AP; Wyatt, RJ1
Beauwens, R; Rentmeesters, M1
Gallagher, JP; Higashi, H; Inanaga, K; Inokuchi, H; Nishi, S1
Johnson, C; Mitchell, J; Stuckey, M1
Kristensen, BI; Pape, L1
Feigenbaum, JJ; Yanai, J1
Blum, JJ; Keegan, FP1
Wolberg, G; Zimmerman, TP1
Annable, L; Chouinard, G1
Barr, R; Crane, FL1
Gerber, CJ; Johnson, MH; Roberts, RW; Wilson, LG1
Allan, T; McClure, DJ; Pecknold, JC; Wrzesinski, L1
Cookson, J; Silverstone, T; Wells, B1
Catravas, JD; Waters, IW1
Brady, RC; Brownstein, BL; Connor, CG1
Hokin-Neaverson, M1
Pappas, BA; Vanderwolf, CH1
Inoue, K; Ito, K; Koizumi, S; Nakazawa, K; Ohno, Y1
Glowa, JR; Wojnicki, FH1
Blakely, RD; Jansen, K; Richelson, E; Tatsumi, M1
Bradley, RJ; Dwyer, DS; Liu, Y1
De Baetselier, P; De Braekeleer, J; Dewit, J; Grabski, R; Malicka-Blaskiewicz, M; Verschueren, H1
Lawrie, S; McIntosh, A; Nadeem, Z1
Lawrie, S; McIntosh, A1
Balit, CR; Isbister, GK; Kilham, HA1
Hodneland, E; Holmsen, H; Oruch, R; Pryme, IF1
Osman, E; Yıldız, M1

Reviews

9 review(s) available for chlorpromazine and pimozide

ArticleYear
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
    Journal of medicinal chemistry, 2003, Jul-03, Volume: 46, Issue:14

    Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists

2003
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target?
    Journal of medicinal chemistry, 2016, 06-09, Volume: 59, Issue:11

    Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Structure; Neuroprotective Agents; Pain; Potassium Channels, Tandem Pore Domain; Structure-Activity Relationship

2016
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Short- and long-term regulation of tyrosine hydroxylase.
    Advances in biochemical psychopharmacology, 1974, Volume: 12, Issue:0

    Topics: Animals; Binding Sites; Brain; Brain Stem; Chlorpromazine; Corpus Striatum; Dibenzothiepins; Dihydroxyphenylalanine; Dopamine; Haloperidol; Hypothalamus; Norepinephrine; Pimozide; Piperazines; Protein Binding; Rats; Reserpine; Sulfides; Time Factors; Tyrosine; Tyrosine 3-Monooxygenase

1974
Psychopharmacological treatment of anorexia nervosa and bulimia. Review and synthesis.
    The Journal of nervous and mental disease, 1983, Volume: 171, Issue:9

    Topics: Adrenocorticotropic Hormone; Anorexia Nervosa; Antidepressive Agents, Tricyclic; Chlorpromazine; Cyproheptadine; Dopamine; Feeding and Eating Disorders; Female; Humans; Hyperphagia; Levodopa; Lithium; Lithium Carbonate; Male; Naloxone; Phenytoin; Pimozide; Serotonin; Zinc

1983
Evidence for the involvement of central dopaminergic receptors in the acute and chronic effects induced by barbiturates.
    Neuropsychobiology, 1983, Volume: 9, Issue:2-3

    Topics: Adenylyl Cyclases; Animals; Barbiturates; Brain; Chlorpromazine; Dopamine; Drug Interactions; Drug Tolerance; Female; Haloperidol; Humans; Hydroxydopamines; Mice; Norepinephrine; Oxidopamine; Pimozide; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Receptors, Dopamine; Substance Withdrawal Syndrome

1983
Schizophrenia.
    Clinical evidence, 2003, Issue:10

    Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clozapine; Cognitive Behavioral Therapy; Dibenzothiepins; Haloperidol; Humans; Olanzapine; Patient Compliance; Perazine; Pimozide; Risperidone; Schizophrenia; Sulpiride

2003
Schizophrenia.
    Clinical evidence, 2004, Issue:12

    Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clozapine; Haloperidol; Humans; Olanzapine; Patient Compliance; Perazine; Pimozide; Risperidone; Schizophrenia; Sulpiride

2004
Antipsychotic poisoning in young children: a systematic review.
    Drug safety, 2005, Volume: 28, Issue:11

    Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Child; Child, Preschool; Chlorpromazine; Clozapine; Dibenzothiazepines; Haloperidol; Humans; Infant; Infant, Newborn; Olanzapine; Pimozide; Piperazines; Poisoning; Quetiapine Fumarate; Quinolones; Risperidone

2005

Trials

12 trial(s) available for chlorpromazine and pimozide

ArticleYear
Token economy, pimozide and chronic schizophrenia.
    The British journal of psychiatry : the journal of mental science, 1978, Volume: 133

    Topics: Behavior Therapy; Chlorpromazine; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Hospitals, Psychiatric; Humans; Long-Term Care; Male; Middle Aged; Pimozide; Reward; Schizophrenia; Token Economy

1978
Tardive dyskinesia treated with pimozide.
    Journal of the neurological sciences, 1975, Volume: 24, Issue:4

    Topics: Aged; Antipsychotic Agents; Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Consciousness Disorders; Drug Therapy, Combination; Female; Fluphenazine; Humans; Male; Middle Aged; Movement Disorders; Parkinson Disease, Secondary; Perphenazine; Phenothiazines; Pimozide; Prochlorperazine; Promazine; Promethazine; Schizophrenia; Thioridazine

1975
Implications of phenothiazine side effects: a study of antiparkinsonian agents in an older population.
    Acta psychiatrica Scandinavica, 1975, Volume: 51, Issue:2

    Topics: Adult; Aged; Antipsychotic Agents; Chlorpromazine; Clinical Trials as Topic; Delayed-Action Preparations; Female; Fluphenazine; Haloperidol; Humans; Long-Term Care; Male; Middle Aged; Parkinson Disease; Parkinson Disease, Secondary; Pimozide; Placebos; Schizophrenia; Thioridazine; Trifluoperazine; Trifluperidol

1975
A double-blind controlled study of pimozide vs chlorpromazine in mania.
    Neuropharmacology, 1979, Volume: 18, Issue:12

    Topics: Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Double-Blind Method; Humans; Pimozide; Time Factors

1979
Clinical trial of pimozide.
    West African journal of pharmacology and drug research, 1976, Volume: 3, Issue:1

    Topics: Adolescent; Adult; Behavior; Chlorpromazine; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Pimozide; Psychiatric Status Rating Scales; Schizophrenia; Time Factors

1976
A randomised controlled trial of prophylactic neuroleptic treatment.
    The British journal of psychiatry : the journal of mental science, 1986, Volume: 148

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Chlorpromazine; Clinical Trials as Topic; Female; Flupenthixol; Follow-Up Studies; Haloperidol; Humans; Male; Middle Aged; Pimozide; Random Allocation; Recurrence; Schizophrenia; Time Factors; Trifluoperazine

1986
A double-blind comparison of pimozide and chlorpromazine in the maintenance care of chronic schizophrenic outpatients.
    Current therapeutic research, clinical and experimental, 1974, Volume: 16, Issue:9

    Topics: Adolescent; Adult; Ambulatory Care; Chlorpromazine; Chronic Disease; Clinical Trials as Topic; Delayed-Action Preparations; Female; Humans; Male; Middle Aged; Pimozide; Psychiatric Status Rating Scales; Schizophrenia; Time Factors

1974
Post-partum mania, dopamine, and estrogens.
    Lancet (London, England), 1982, Sep-18, Volume: 2, Issue:8299

    Topics: Affective Disorders, Psychotic; Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Pimozide; Pregnancy; Puerperal Disorders; Receptors, Dopamine

1982
Pimozide in the treatment of newly admitted schizophrenic patients.
    Psychopharmacology, 1982, Volume: 76, Issue:1

    Topics: Acute Disease; Adult; Chlorpromazine; Double-Blind Method; Dyskinesia, Drug-Induced; Female; Humans; Male; Middle Aged; Parkinson Disease, Secondary; Pimozide; Prolactin; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology

1982
Pimozide versus chlorpromazine in chronic schizophrenia: a 52 week double-blind study of maintenance therapy.
    The Journal of clinical psychiatry, 1982, Volume: 43, Issue:2

    Topics: Adult; Chlorpromazine; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Pimozide; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Social Adjustment

1982
Comparison of pimozide and chlorpromazine in acute schizophrenia.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1982, Volume: 27, Issue:3

    Topics: Acute Disease; Adult; Chlorpromazine; Clinical Trials as Topic; Double-Blind Method; Dyskinesia, Drug-Induced; Female; Humans; Male; Middle Aged; Pimozide; Psychiatric Status Rating Scales; Random Allocation; Schizophrenia; Schizophrenic Psychology

1982
Double-blind comparative clinical trial of pimozide and chlorpromazine in mania. A test of the dopamine hypothesis.
    Acta psychiatrica Scandinavica, 1981, Volume: 64, Issue:5

    Topics: Adult; Affective Disorders, Psychotic; Aged; Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Pimozide; Psychiatric Status Rating Scales; Receptors, Dopamine

1981

Other Studies

130 other study(ies) available for chlorpromazine and pimozide

ArticleYear
Synthesis and biological evaluation of some 2-amino-4-aryl-3H-1,5-benzodiazepine analogues of clozapine.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:9

    Topics: Adenylyl Cyclase Inhibitors; Animals; Antipsychotic Agents; Avoidance Learning; Brain; Clozapine; Corpus Striatum; Dextroamphetamine; Dibenzazepines; Dopamine; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mice; Rats

1978
Pharmacology of human dopamine D3 receptor expressed in a mammalian cell line: comparison with D2 receptor.
    European journal of pharmacology, 1992, Apr-10, Volume: 225, Issue:4

    Topics: Animals; Chlorides; CHO Cells; Cricetinae; Dopamine; Dopamine Agents; Dopamine Antagonists; Guanylyl Imidodiphosphate; Humans; Lithium; Lithium Chloride; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D3; Sodium Chloride; Sulpiride; Transfection

1992
Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics.
    Nature, 1990, Sep-13, Volume: 347, Issue:6289

    Topics: Amino Acid Sequence; Animals; Antipsychotic Agents; Base Sequence; Brain Chemistry; Cell Line; Cloning, Molecular; Cricetinae; DNA; DNA Restriction Enzymes; Dopamine; Guanylyl Imidodiphosphate; Molecular Sequence Data; Nucleic Acid Hybridization; Polymerase Chain Reaction; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; RNA, Messenger; Sequence Homology, Nucleic Acid; Tissue Distribution

1990
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Cognition-activating properties of 3-(Aryloxy)pyridines.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:3

    Topics: Animals; Cognition; Dose-Response Relationship, Drug; Male; Mice; Psychotropic Drugs; Pyridines; Structure-Activity Relationship

1981
Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:3

    Topics: Animals; Antipsychotic Agents; Cell Line; Molecular Structure; Rats; Receptors, Serotonin

1994
Expression and pharmacological characterization of the human D3 dopamine receptor.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:1

    Topics: Animals; Binding, Competitive; Cells, Cultured; CHO Cells; Cricetinae; Dopamine; Dopamine Antagonists; GTP-Binding Proteins; Guanine Nucleotides; Humans; Potassium Channels; Rats; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D3; Recombinant Proteins; Second Messenger Systems; Sulpiride

1994
Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35S]GTPgammaS binding study.
    European journal of pharmacology, 1998, Aug-21, Volume: 355, Issue:2-3

    Topics: Animals; Antipsychotic Agents; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Sulfur Radioisotopes

1998
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers.
    Journal of medicinal chemistry, 2002, Aug-29, Volume: 45, Issue:18

    Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go-Go Potassium Channels; Long QT Syndrome; Models, Molecular; Molecular Conformation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2002
H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:3

    Topics: Animals; Antipsychotic Agents; Discriminant Analysis; Drug Evaluation, Preclinical; Forecasting; Humans; Protein Binding; Receptors, Histamine H1; Statistics, Nonparametric; Weight Gain

2003
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2003
A two-state homology model of the hERG K+ channel: application to ligand binding.
    Bioorganic & medicinal chemistry letters, 2005, Mar-15, Volume: 15, Issue:6

    Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Ligands; Models, Biological; Models, Molecular; Potassium Channels, Voltage-Gated; Protein Binding; Protein Conformation

2005
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Support vector machines classification of hERG liabilities based on atom types.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve

2008
GRIND-based 3D-QSAR and CoMFA to investigate topics dominated by hydrophobic interactions: the case of hERG K+ channel blockers.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:5

    Topics: Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Potassium Channel Blockers; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk.
    Cardiovascular research, 2011, Jul-01, Volume: 91, Issue:1

    Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
MICE models: superior to the HERG model in predicting Torsade de Pointes.
    Scientific reports, 2013, Volume: 3

    Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
The search for the dopamine receptor: tribulations.
    Psychopharmacology communications, 1975, Volume: 1, Issue:2

    Topics: Chlorpromazine; Dialysis; Dopamine; Fluphenazine; Haloperidol; Hydrogen-Ion Concentration; Membranes, Artificial; Pimozide; Promethazine; Receptors, Drug; Temperature; Time Factors

1975
Altered hypothermic responsivness to (+)-amphetamine.
    The Journal of pharmacy and pharmacology, 1976, Volume: 28, Issue:2

    Topics: Animals; Apomorphine; Body Temperature; Chlorpromazine; Depression, Chemical; Dextroamphetamine; Drug Tolerance; Guinea Pigs; Male; Pimozide

1976
Potentiation by alpha-methyltyrosine of the suppression of food-reinforced lever-pressing behaviour induced by antipsychotic drugs.
    Acta pharmacologica et toxicologica, 1977, Volume: 40, Issue:1

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Catecholamines; Chlorpromazine; Clozapine; Conditioning, Operant; Drug Synergism; Feeding Behavior; Haloperidol; Male; Methyltyrosines; Phenoxybenzamine; Pimozide; Rats; Receptors, Adrenergic; Thioridazine

1977
The different influence of predominantly antiadrenergic and antidopaminergic neuroleptics on the estrous cycle in rats.
    Pharmacology, 1977, Volume: 15, Issue:2

    Topics: Animals; Chlorpromazine; Diestrus; Dose-Response Relationship, Drug; Estrus; Female; Fluspirilene; Methotrimeprazine; Phenothiazines; Pimozide; Pregnancy; Pseudopregnancy; Rats; Receptors, Adrenergic; Thioridazine; Tranquilizing Agents

1977
Blockade of intracranial self-stimulation by antipsychotic drugs: failure to correlate with central alpha-noradrenergic blockade.
    Psychopharmacology, 1977, Aug-16, Volume: 53, Issue:3

    Topics: Animals; Antipsychotic Agents; Chlorpromazine; Clozapine; Depression, Chemical; Electric Stimulation; Male; Muscle Contraction; Phenoxybenzamine; Pimozide; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Reflex; Self Stimulation; Thioridazine; Time Factors

1977
Effect of monoamine receptor agonists and antagonists on cyclic AMP accumulation in human cerebral cortex slices.
    Canadian journal of physiology and pharmacology, 1977, Volume: 55, Issue:6

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adult; Cerebral Cortex; Child; Chlorpromazine; Cyclic AMP; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Kinetics; Male; Norepinephrine; Phentolamine; Pimozide; Propranolol; Receptors, Adrenergic

1977
[Hyperprolactinemic effect of anti-psychotic drugs].
    Bollettino della Societa italiana di biologia sperimentale, 1978, Jan-30, Volume: 54, Issue:2

    Topics: Antipsychotic Agents; Chlorpromazine; Female; Haloperidol; Humans; Male; Pimozide; Prolactin; Stimulation, Chemical

1978
The effect of neuroleptic drugs on drinking induced by central administration of angiotensin or carbachol.
    Psychopharmacology, 1979, Feb-28, Volume: 60, Issue:3

    Topics: Angiotensin II; Animals; Antipsychotic Agents; Carbachol; Chlorpromazine; Clozapine; Dopamine; Drinking Behavior; Flupenthixol; Fluphenazine; Haloperidol; Injections, Intraperitoneal; Injections, Intraventricular; Male; Pimozide; Rats; Sulpiride

1979
Phencyclidine-induced stereotyped behavior in rats: dose response effects and antagonism by neuroleptics.
    Life sciences, 1979, Jun-11, Volume: 24, Issue:24

    Topics: Animals; Antipsychotic Agents; Behavior; Chlorpromazine; Dose-Response Relationship, Drug; Haloperidol; Humans; Male; Motor Activity; Phencyclidine; Pimozide; Rats; Stereotyped Behavior; Time Factors

1979
Is a dopaminergic system involved in thyrotropin releasing hormone induced hyperthermia and in its potentiation by amphetamine?
    Progress in neuro-psychopharmacology, 1979, Volume: 3, Issue:4

    Topics: alpha-Methyltyrosine; Amphetamine; Animals; Apomorphine; Chlorpromazine; Dopamine; Dopamine Agents; Female; Fever; Haloperidol; Levodopa; Methyltyrosines; Mice; Neurotransmitter Agents; p-Chloroamphetamine; Pimozide; Thyrotropin-Releasing Hormone

1979
Beta-phenylethylamine and locomotor activity in mice. Interaction with catecholaminergic neurones and receptors.
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:4

    Topics: Animals; Apomorphine; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Catecholamines; Chlorpromazine; Ditiocarb; Drug Interactions; Haloperidol; Male; Methyltyrosines; Mice; Motor Activity; Neurons; Perphenazine; Phenethylamines; Phenoxybenzamine; Phentolamine; Pimozide; Propranolol; Receptors, Drug; Reserpine

1975
The effect of psychotropic drugs on the TSH-response to thyroliberin (TRH).
    Neuroendocrinology, 1977, Volume: 24, Issue:2

    Topics: Chlorpromazine; Fusaric Acid; Humans; Levodopa; Norepinephrine; Pimozide; Pituitary Gland, Anterior; Propranolol; Psychotropic Drugs; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Thioridazine; Thyrotropin; Thyrotropin-Releasing Hormone

1977
Effects of dopaminergic drugs and acute medial forebrain bundle lesions on striatal acetylcholine levels.
    Life sciences, 1975, Jan-01, Volume: 16, Issue:1

    Topics: Acetylcholine; Animals; Antipsychotic Agents; Brain; Chlorpromazine; Corpus Striatum; Haloperidol; Hippocampus; Pimozide; Rats

1975
Effects of dopaminergic receptor agonists and antagonists on the activity of the neo-striatal cholinergic system.
    Brain research, 1975, Feb-07, Volume: 84, Issue:2

    Topics: Acetylcholine; Animals; Apomorphine; Brain Chemistry; Chemistry Techniques, Analytical; Chlorpromazine; Corpus Striatum; Depression, Chemical; Haloperidol; Hippocampus; Hydroxydopamines; Male; Parietal Lobe; Phenothiazines; Pimozide; Rats; Stimulation, Chemical; Tranquilizing Agents

1975
[Cellular effect of neuroleptics].
    Deutsche medizinische Wochenschrift (1946), 1975, Jun-20, Volume: 100, Issue:25

    Topics: Adenylyl Cyclases; Basal Ganglia Diseases; Biological Transport, Active; Catecholamines; Chlorpromazine; Dopamine; Dopamine Antagonists; Histamine H1 Antagonists; Humans; Norepinephrine; Pimozide; Receptors, Drug; Reserpine; Schizophrenia; Serotonin Antagonists; Tranquilizing Agents

1975
Dopamine receptors and cholinergic neurons in the rat neostriatum.
    Advances in neurology, 1975, Volume: 9

    Topics: Acetylcholine; Animals; Apomorphine; Chlorpromazine; Corpus Striatum; Depression, Chemical; Dopamine; Drug Antagonism; Haloperidol; Male; Phenothiazines; Pimozide; Putamen; Rats; Receptors, Drug; Stimulation, Chemical; Substantia Nigra

1975
The effect of penfluridol and some psychotropic drugs on monoamine metabolism in central nervous system.
    European journal of pharmacology, 1975, Volume: 31, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Brain; Brain Chemistry; Chlordiazepoxide; Chlorpromazine; Diazepam; Dopamine; Haloperidol; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Mice; Norepinephrine; Penfluridol; Pimozide; Piperazines; Piperidines; Psychotropic Drugs; Rats; Serotonin

1975
Effect of thioridazine, clozapine and other antipsychotics on the kinetic state of tyrosine hydroxylase and on the turnover rate of dopamine in striatum and nucleus accumbens.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 194, Issue:1

    Topics: Adenylyl Cyclases; Animals; Antipsychotic Agents; Brain; Brain Chemistry; Catecholamines; Chlorpromazine; Clozapine; Corpus Striatum; Dibenzothiepins; Dopamine; Dose-Response Relationship, Drug; Haloperidol; Hypothalamus; Kinetics; Male; Norepinephrine; Pimozide; Promethazine; Rats; Thioridazine; Tyrosine 3-Monooxygenase

1975
On the significance of the increase in homovanillic acid (HVA) caused by antipsychotic drugs in corpus striatum and limbic forebrain.
    Psychopharmacologia, 1975, Aug-21, Volume: 43, Issue:2

    Topics: Animals; Antipsychotic Agents; Basal Ganglia Diseases; Chlorpromazine; Clozapine; Corpus Striatum; Dextroamphetamine; Dopamine; Dose-Response Relationship, Drug; Haloperidol; Homovanillic Acid; Humans; Limbic System; Male; Phenylacetates; Pimozide; Rats; Receptors, Drug; Rotation; Stereotyped Behavior; Substantia Nigra; Thioridazine

1975
Characteristics of beta-phenethylamine self-administration by dog.
    Pharmacology, biochemistry, and behavior, 1977, Volume: 6, Issue:6

    Topics: Animals; Chlorpromazine; Dextroamphetamine; Dogs; Female; Male; Monoamine Oxidase Inhibitors; Motor Activity; Phenethylamines; Phenoxybenzamine; Pimozide; Reinforcement, Psychology; Self Administration

1977
[In vivo binding of tritiated agents in mouse brain].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1977, Oct-17, Volume: 285, Issue:9

    Topics: Animals; Apomorphine; Brain; Cerebellum; Chlorpromazine; Corpus Striatum; Haloperidol; Male; Mice; Pimozide; Tissue Distribution

1977
Effects of apomorphine combined with chlorpromazine and pimozide on the estrous cycle in rats.
    Endokrinologie, 1977, Volume: 70, Issue:2

    Topics: Animals; Apomorphine; Chlorpromazine; Diestrus; Estrus; Female; Metestrus; Pimozide; Pregnancy; Rats

1977
Paramethoxyphenylethylamine (PMPEA): some behavioral observations in rats.
    Communications in psychopharmacology, 1977, Volume: 1, Issue:1

    Topics: Animals; Behavior, Animal; Chlorpromazine; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Humans; Male; Motor Activity; Pimozide; Rats; Reaction Time; Stereotyped Behavior; Tyramine

1977
Neuroleptics attentuate stereotyped behavior induced by beta-phenylethylamine in rats.
    Biological psychiatry, 1978, Volume: 13, Issue:2

    Topics: Animals; Behavior; Chlorpromazine; Clozapine; Diazepam; Dose-Response Relationship, Drug; Drug Antagonism; Drug Evaluation; Haloperidol; Humans; Male; Phenethylamines; Pimozide; Rats; Receptors, Dopamine; Stereotyped Behavior; Tranquilizing Agents

1978
[Effect of neuroleptics on acetylcholine metabolism in the basal ganglia of the brain].
    Biulleten' eksperimental'noi biologii i meditsiny, 1978, Volume: 85, Issue:4

    Topics: Acetylcholine; Acetylcholinesterase; Animals; Basal Ganglia; Chlorpromazine; Clozapine; Haloperidol; Male; Pimozide; Rats; Tranquilizing Agents

1978
Acute effects of adrenergic receptor blocking drugs and neuroleptic agents on pulsatile discharges of luteinizing hormone in the ovariectomized rat.
    Neuroendocrinology, 1978, Volume: 26, Issue:2

    Topics: Animals; Castration; Chlorpromazine; Female; Haloperidol; Luteinizing Hormone; Phenoxybenzamine; Phentolamine; Pimozide; Propranolol; Rats; Sympatholytics; Time Factors; Tranquilizing Agents

1978
Luteinizing hormone releasing action of N-methyl aspartate is blocked by GABA or taurine but not by dopamine antagonists.
    Brain research, 1978, Dec-15, Volume: 158, Issue:2

    Topics: Animals; Aspartic Acid; Chlorpromazine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Hypothalamus, Middle; Luteinizing Hormone; Male; Neurosecretion; Pimozide; Rats; Receptors, Dopamine; Taurine

1978
Comparison of the action of lysergic acid diethylamide and apomorphine on the copulatory response in the female rat.
    Psychopharmacology, 1976, Sep-29, Volume: 49, Issue:3

    Topics: Animals; Apomorphine; Chlorpromazine; Copulation; Dopamine; Female; Lysergic Acid Diethylamide; Motor Activity; Pimozide; Posture; Rats; Serotonin

1976
Analysis of the mechanism of the protective activity of some sympathomimetic amines in experimental ulcers.
    Pharmacology, 1977, Volume: 15, Issue:3

    Topics: Amitriptyline; Amphetamine; Animals; Apomorphine; Butyrophenones; Catecholamines; Chlorpromazine; Cocaine; Levodopa; Morphine; Pimozide; Rats; Receptors, Adrenergic; Reserpine; Restraint, Physical; Stomach Ulcer; Sympathomimetics; Trifluperidol

1977
Apparent lack of a dopaminergic-cholinergic link in the rat nucleus accumbens septi-tuberculum olfactorium.
    Brain research, 1977, Oct-28, Volume: 135, Issue:2

    Topics: Acetylcholine; Animals; Apomorphine; Bromocriptine; Chlorpromazine; Clozapine; Dextroamphetamine; Haloperidol; Nucleus Accumbens; Olfactory Bulb; Pimozide; Piribedil; Rats; Receptors, Cholinergic; Receptors, Dopamine; Septal Nuclei

1977
Comparison of the inhibitory effects of neuroleptic drugs on adenylate cyclase in rat tissues stimulated by dopamine, noradrenaline and glucagon.
    Biochemical pharmacology, 1976, Mar-01, Volume: 25, Issue:5

    Topics: Adenylyl Cyclase Inhibitors; Adipose Tissue; Animals; Chlorpromazine; Chlorprothixene; Corpus Striatum; Dopamine; Flupenthixol; Glucagon; Haloperidol; In Vitro Techniques; Liver; Membranes; Norepinephrine; Pimozide; Promazine; Rats; Receptors, Adrenergic; Tranquilizing Agents

1976
Evidence for adrenergic mediation of cholinergic inhibition of prolactin release.
    Endocrinology, 1976, Volume: 99, Issue:3

    Topics: Animals; Atropine; Atropine Derivatives; Chlorpromazine; Female; Haloperidol; Male; Pilocarpine; Pimozide; Prolactin; Rats; Reserpine; Sex Factors

1976
Effects of chronic treatment with neuroleptics on striatal acetylcholine concentration.
    Journal of neurochemistry, 1976, Volume: 27, Issue:1

    Topics: Acetylcholine; Animals; Chlorpromazine; Corpus Striatum; Haloperidol; Male; Pimozide; Rats; Time Factors; Tranquilizing Agents

1976
The inhibitory action of dopamine on the anterior tibialis muscle preparation antagonized by pimozide and chlorpromazine.
    Archives internationales de pharmacodynamie et de therapie, 1976, Volume: 221, Issue:1

    Topics: Animals; Blood Pressure; Cats; Chlorpromazine; Dopamine; Dopamine Antagonists; Drug Interactions; Edrophonium; In Vitro Techniques; Male; Muscle Contraction; Muscles; Phentolamine; Pimozide; Propranolol

1976
Comparative studies on the effects of metoclopramide and some known neuroleptics on the EEG of the conscious rat [proceedings].
    British journal of pharmacology, 1976, Volume: 58, Issue:2

    Topics: Animals; Chlorpromazine; Dextroamphetamine; Electroencephalography; Haloperidol; Male; Metoclopramide; Pimozide; Rats; Tranquilizing Agents

1976
Restoration of self-stimulation inhibited by neuroleptics.
    European journal of pharmacology, 1976, Volume: 40, Issue:1

    Topics: Amphetamine; Animals; Apomorphine; Chlorpromazine; Cocaine; Dexetimide; Dopamine Antagonists; Isoquinolines; Male; Pimozide; Rats; Receptors, Dopamine; Self Stimulation; Tranquilizing Agents

1976
Role of noradrenergic and dopaminergic processes in amphetamine self-administration.
    Pharmacology, biochemistry, and behavior, 1976, Volume: 5, Issue:4

    Topics: Animals; Chlorpromazine; Dextroamphetamine; Dogs; Dopamine; Female; Male; Methoxamine; Norepinephrine; Phenoxybenzamine; Pimozide; Self Administration

1976
Effect of neuroleptic drugs on mouse jumping induced by L-DOPA in amphetamine treated mice.
    Neuropharmacology, 1976, Volume: 15, Issue:11

    Topics: Amphetamine; Animals; Behavior; Chlorpromazine; Clozapine; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Humans; Levodopa; Male; Mice; Pimozide; Promethazine; Psychotropic Drugs; Stereotyped Behavior; Thioridazine; Tranquilizing Agents

1976
The interaction of neuroleptic and muscarinic agents with central dopaminergic systems.
    British journal of pharmacology, 1975, Volume: 54, Issue:1

    Topics: Adenylyl Cyclase Inhibitors; Animals; Apomorphine; Behavior, Animal; Chlorpromazine; Clopenthixol; Clozapine; Corpus Striatum; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Flupenthixol; Male; Methamphetamine; Models, Biological; Oxotremorine; Parasympathomimetics; Pimozide; Rats; Scopolamine; Substantia Nigra; Thioridazine; Tranquilizing Agents

1975
Inhibition of circling behavior by neuroleptic drugs in mice with unilateral 6-hydroxydopamine lesions of the striatum.
    Psychopharmacologia, 1975, Dec-31, Volume: 45, Issue:2

    Topics: Animals; Apomorphine; Basal Ganglia Diseases; Behavior; Biogenic Amines; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Chlorpromazine; Clozapine; Corpus Striatum; Dextroamphetamine; Diazepam; Dopamine; Haloperidol; Humans; Hydroxydopamines; Levodopa; Male; Metoclopramide; Mice; Motor Activity; Pentobarbital; Phenoxybenzamine; Pimozide; Promethazine; Stereotyped Behavior; Tranquilizing Agents

1975
Muscarinic cholinergic receptor binding: influence of pimozide and chlorpromazine metabolites.
    Life sciences, 1976, Apr-01, Volume: 18, Issue:7

    Topics: Animals; Binding, Competitive; Brain; Chlorpromazine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Pimozide; Rats; Receptors, Cholinergic; Structure-Activity Relationship

1976
Neuroleptic-induced changes in the anxiolytic and myorelaxant properties of diazepam in the rat.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 41, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Chlorpromazine; Diazepam; Drug Interactions; Haloperidol; Male; Muscle Relaxants, Central; Pimozide; Rats; Thioridazine

1992
Relation between protein kinase C and calmodulin systems in cerebrovascular contraction: investigation of the pathogenesis of vasospasm after subarachnoid hemorrhage.
    Neurosurgery, 1992, Volume: 31, Issue:4

    Topics: Animals; Basilar Artery; Brain; Calmodulin; Chlorpromazine; Dogs; Dose-Response Relationship, Drug; Ischemic Attack, Transient; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Pimozide; Potassium; Protein Kinase C; Signal Transduction; Subarachnoid Hemorrhage; Trifluoperazine; Vasoconstriction

1992
Conditioned drug effects of pimozide, haloperidol and chlorpromazine on methamphetamine-induced behavior.
    The Japanese journal of psychiatry and neurology, 1990, Volume: 44, Issue:3

    Topics: Animals; Arousal; Chlorpromazine; Conditioning, Classical; Disease Models, Animal; Dose-Response Relationship, Drug; Haloperidol; Male; Methamphetamine; Motor Activity; Neurocognitive Disorders; Orientation; Pimozide; Rats; Rats, Inbred Strains; Schizophrenic Psychology; Stereotyped Behavior

1990
The role of calmodulin in the responses to adrenocorticotropin of plasma membranes from adrenal cells.
    Endocrinology, 1990, Volume: 126, Issue:5

    Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Calmodulin; Cell Membrane; Chlorpromazine; Colforsin; Cyclic AMP; Immunoglobulin G; Mice; Pimozide; Sulfonamides; Trifluoperazine; Tumor Cells, Cultured

1990
Increased lethality of calmodulin antagonists and bleomycin to human bone marrow and bleomycin-resistant malignant cells.
    Cancer research, 1986, Volume: 46, Issue:5

    Topics: Bleomycin; Bone Marrow; Bone Marrow Cells; Calmodulin; Cell Survival; Chlorpromazine; Dose-Response Relationship, Drug; Drug Resistance; Drug Synergism; Hematopoietic Stem Cells; Humans; Melitten; Neoplasms, Experimental; Pimozide

1986
Enhanced bleomycin-induced DNA damage and cytotoxicity with calmodulin antagonists.
    Molecular pharmacology, 1985, Volume: 27, Issue:3

    Topics: Animals; Bleomycin; Calmodulin; Cell Survival; Chlorpromazine; DNA; Drug Synergism; Intercellular Signaling Peptides and Proteins; Leukemia L1210; Melitten; Mice; Peptides; Pimozide; Sulfonamides; Trifluoperazine; Wasp Venoms

1985
Neuroleptic drugs attenuate calcium influx and tension development in rabbit thoracic aorta: effects of pimozide, penfluridol, chlorpromazine, and haloperidol.
    Proceedings of the National Academy of Sciences of the United States of America, 1985, Volume: 82, Issue:4

    Topics: Animals; Antipsychotic Agents; Aorta, Thoracic; Calcium; Calcium Channel Blockers; Chlorpromazine; Haloperidol; In Vitro Techniques; Ion Channels; Male; Muscle Contraction; Penfluridol; Pimozide; Rabbits

1985
Effect of various catecholamine antagonists on prolactin secretion in conscious male rabbits.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1985, Volume: 180, Issue:1

    Topics: Animals; Antipsychotic Agents; Benzamides; Catecholamines; Chlorpromazine; Consciousness; Haloperidol; Male; Metoprolol; Pimozide; Prazosin; Prolactin; Propranolol; Rabbits; Radioimmunoassay; Yohimbine

1985
[Comparative study of the pharmacological properties of sultopride sulpiride and other antipsychotic drugs: influence of sultopride, sulpiride and other antipsychotic drugs on spontaneous locomotor activity and changes in locomotor activity induced by apo
    Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology, 1986, Volume: 6, Issue:3

    Topics: Amisulpride; Animals; Antipsychotic Agents; Apomorphine; Chlorpromazine; Clonidine; Drug Interactions; Haloperidol; Imipramine; Male; Mice; Motor Activity; Pimozide; Sulpiride; Yohimbine

1986
Inhibition of growth of C6 astrocytoma cells by inhibitors of calmodulin.
    Life sciences, 1985, Jan-28, Volume: 36, Issue:4

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Astrocytoma; Calmodulin; Cell Division; Cell Line; Chlorpromazine; Imidazoles; Melitten; Pimozide; Rats; Structure-Activity Relationship; Trifluoperazine

1985
The curve-shift paradigm in self-stimulation.
    Physiology & behavior, 1986, Volume: 37, Issue:1

    Topics: Animals; Brain; Chlorpromazine; Conditioning, Operant; Dose-Response Relationship, Drug; Electric Stimulation; Hypothalamic Area, Lateral; Male; Methocarbamol; Neurons; Pimozide; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Self Stimulation; Synapses

1986
Chlorpromazine and pimozide alter reinforcement efficacy and motor performance.
    Psychopharmacology, 1986, Volume: 88, Issue:3

    Topics: Animals; Chlorpromazine; Conditioning, Operant; Male; Pimozide; Psychomotor Performance; Rats; Rats, Inbred Strains; Reinforcement, Psychology

1986
Localization of 11C-radiopharmaceuticals in the Greene melanoma of hamsters.
    European journal of nuclear medicine, 1985, Volume: 10, Issue:9-10

    Topics: Animals; Benzodiazepinones; Carbon Radioisotopes; Chlorpromazine; Cricetinae; Flumazenil; Flunitrazepam; Gallium Radioisotopes; Isotope Labeling; Ketanserin; Melanoma; Mesocricetus; Methionine; Neoplasm Transplantation; Pimozide; Piperidines; Quinuclidinyl Benzilate; Radionuclide Imaging; Tissue Distribution

1985
Susceptibility to drug-induced hypotension in post-partum psychosis.
    International clinical psychopharmacology, 1986, Volume: 1, Issue:1

    Topics: Adult; Chlorpromazine; Female; Humans; Hypotension, Orthostatic; Pimozide; Pregnancy; Psychotic Disorders; Psychotropic Drugs; Puerperal Disorders; Thioridazine; Trifluoperazine

1986
Copulatory behavior in the male rat after impaired monoaminergic neurotransmission.
    Acta physiologica Scandinavica. Supplementum, 1973, Volume: 400

    Topics: Adrenalectomy; Adrenergic Agents; Amino Acids; Animals; Castration; Chlorpromazine; Copulation; Depression, Chemical; Disulfides; Dopamine beta-Hydroxylase; Ejaculation; Female; Fenclonine; Imidazoles; Male; Methyltyrosines; Motor Activity; Phenoxybenzamine; Pimozide; Propranolol; Rats; Reserpine; Sexual Behavior, Animal; Stimulation, Chemical; Sympatholytics; Testosterone; Tetrabenazine; Time Factors; Tranquilizing Agents

1973
Antipsychotic drugs stimulate prolactin release.
    Psychopharmacologia, 1974, Volume: 40, Issue:2

    Topics: Animals; Chlorpromazine; Dopamine; Female; Fluphenazine; Haloperidol; Male; Phenothiazines; Pimozide; Prolactin; Promethazine; Rats; Receptors, Drug; Sex Factors; Stimulation, Chemical; Sulpiride; Thiethylperazine; Thioridazine; Tranquilizing Agents

1974
Dopamine and the pharmacology of schizophrenia: the state of the evidence.
    Journal of psychiatric research, 1974, Volume: 11

    Topics: Amphetamine; Animals; Brain; Cats; Caudate Nucleus; Chlorpromazine; Dogs; Dopamine; Haloperidol; Haplorhini; Humans; Limbic System; Norepinephrine; Pimozide; Psychoses, Substance-Induced; Rats; Receptors, Drug; Schizophrenia; Species Specificity; Stereoisomerism; Stereotyped Behavior; Structure-Activity Relationship; Thiethylperazine; Thioridazine

1974
Inhibitory role of dopamine and 5-hydroxytryptamine in the sexual behaviour of female rats.
    European journal of pharmacology, 1974, Volume: 29, Issue:1

    Topics: Adrenal Glands; Adrenalectomy; Animals; Castration; Chlorpromazine; Depression, Chemical; Dioxoles; Disulfides; Dopamine Antagonists; Estradiol; Female; Fenclonine; Fenfluramine; Imidazoles; Male; Methyltyrosines; Norepinephrine; Ovary; Pimozide; Piperazines; Progesterone; Rats; Serotonin Antagonists; Sexual Behavior, Animal; Spiperone; Stimulation, Chemical; Time Factors

1974
Compulsive gnawing in rats after implantation of drugs into the ventral thalamus. A contribution to the mechanism of morphine action.
    British journal of pharmacology, 1974, Volume: 51, Issue:2

    Topics: Amphetamine; Animals; Apomorphine; Brain; Chlorpromazine; Compulsive Behavior; Corpus Striatum; Disulfiram; Dose-Response Relationship, Drug; Drug Synergism; Fenclonine; Haloperidol; Humans; Meperidine; Methadone; Methyldopa; Methyltyrosines; Morphine; Nalorphine; Phenoxybenzamine; Phentolamine; Pimozide; Rats; Thalamus

1974
Histological and molecular biochemistry.
    Modern problems of pharmacopsychiatry, 1970, Volume: 5

    Topics: Animals; Brain; Brain Chemistry; Chlorpromazine; Dopamine; Fluorescence; Haloperidol; Histocytochemistry; Humans; Neurons; Norepinephrine; Pimozide; Receptors, Adrenergic; Receptors, Drug; Reserpine; Serotonin; Synaptic Transmission; Tranquilizing Agents

1970
Dopamine-induced inhibition of synaptic transmission in lumbar paravertebral ganglia of the dog.
    Naunyn-Schmiedeberg's archives of pharmacology, 1973, Volume: 279, Issue:2

    Topics: Acetamides; Action Potentials; Animals; Antihypertensive Agents; Apomorphine; Blood Pressure; Butyrophenones; Catecholamines; Chlorpromazine; Dogs; Dopamine; Dose-Response Relationship, Drug; Ergonovine; Ganglia, Spinal; Haloperidol; Isoproterenol; Methane; Norepinephrine; Phenoxybenzamine; Phentolamine; Pimozide; Piperidines; Synapses; Synaptic Transmission; Vasodilator Agents

1973
Proceedings: The role of the presynaptic receptors in regulating noradrenaline overflow by nerve stimulation.
    Acta physiologica latino americana, 1973, Volume: 23, Issue:6

    Topics: Animals; Cats; Chlorpromazine; Nictitating Membrane; Norepinephrine; Phenoxybenzamine; Phentolamine; Pimozide; Receptors, Neurotransmitter; Synaptic Transmission

1973
The effect of L-dopa on neuroleptic-induced catalepsy.
    The Journal of pharmacy and pharmacology, 1972, Volume: 24, Issue:9

    Topics: Animals; Catalepsy; Chlorpromazine; Dihydroxyphenylalanine; Fenclonine; Fluphenazine; Humans; Male; Nialamide; Pimozide; Rats; Spiro Compounds; Time Factors; Tranquilizing Agents

1972
Regulation of striatal acetylcholine concentration by dopamine receptors.
    Nature, 1974, Oct-11, Volume: 251, Issue:5475

    Topics: Acetylcholine; Animals; Apomorphine; Brain Chemistry; Carbidopa; Chlorpromazine; Corpus Striatum; Dextroamphetamine; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Haloperidol; Male; Pimozide; Rats; Receptors, Adrenergic

1974
Ketamine catalepsy and anesthesia in dogs pretreated with antiserotonergic or antidopaminergic neuroleptics or with anticholinergic agents.
    Pharmacological research communications, 1974, Volume: 6, Issue:3

    Topics: Anesthesia; Animals; Atropine; Catalepsy; Chlorpromazine; Dibenzothiepins; Dihydroxyphenylalanine; Dogs; Drug Synergism; Female; Humans; Ketamine; Male; Mecamylamine; Muscle Tonus; Parasympatholytics; Pimozide; Piperazines; Reflex; Respiration; Serotonin Antagonists; Sulfides

1974
Self-stimulation of noradrenergic cell group (A6) in locus coeruleus of rats.
    Journal of comparative and physiological psychology, 1973, Volume: 85, Issue:3

    Topics: Animals; Cerebral Ventricles; Chlorpromazine; Conditioning, Operant; Dextroamphetamine; Dose-Response Relationship, Drug; Electrodes, Implanted; Exploratory Behavior; Hypothalamus; Male; Methyltyrosines; Neurons; Norepinephrine; Pimozide; Pons; Rats; Reward; Self Stimulation; Stereotaxic Techniques

1973
Diencephalic involvement in generalized lipodystrophy: rationale and treatment with the neuroleptic agent, pimozide.
    Acta endocrinologica, 1974, Volume: 77, Issue:2

    Topics: Animals; Child; Chlorpromazine; Cholesterol; Corticotropin-Releasing Hormone; Depression, Chemical; Diencephalon; Female; Gonadotropin-Releasing Hormone; Growth Hormone; Humans; Hydrocortisone; Insulin; Lipids; Lipodystrophy; Liver Function Tests; Male; Pimozide; Rats; Stimulation, Chemical; Time Factors; Triglycerides

1974
The effects of D-amphetamine and related drugs on colonic temperatures of rats kept at various ambient temperatures.
    Life sciences. Pt. 1: Physiology and pharmacology, 1972, Sep-15, Volume: 11, Issue:18

    Topics: Animals; Body Temperature; Chemical Precipitation; Chlorpromazine; Colon; Depression, Chemical; Dextroamphetamine; Dose-Response Relationship, Drug; Drug Interactions; Fenfluramine; Injections, Intraperitoneal; Male; Pimozide; Rats; Reserpine; Stimulation, Chemical; Temperature; Time Factors; Tyramine

1972
Comparison of the behavioral depressant effects of biogenic amine depleting and neuroleptic agents following various 6-hydroxydopamine treatments.
    Psychopharmacologia, 1973, Jul-17, Volume: 31, Issue:2

    Topics: Animals; Behavior, Animal; Brain; Brain Chemistry; Chlorpromazine; Depression, Chemical; Dopamine; Dopamine beta-Hydroxylase; Haloperidol; Hydroxydopamines; Male; Methyltyrosines; Norepinephrine; Pimozide; Rats; Reinforcement, Psychology; Reserpine; Thiazoles; Thiourea; Time Factors; Tranquilizing Agents

1973
Increase of 3-methoxy-4-hydroxyphenylethylene glycol in rat brain by neuroleptic drugs.
    European journal of pharmacology, 1973, Volume: 23, Issue:2

    Topics: Animals; Brain Chemistry; Chlorpromazine; Dibenzazepines; Dibenzothiepins; Dose-Response Relationship, Drug; Glycols; Haloperidol; Male; Methoxyhydroxyphenylglycol; Pimozide; Piperazines; Rats; Sulfides; Thioridazine; Tranquilizing Agents

1973
Amphetamine- and apomorphine-induced alteration of the behavior of rats submitted to a competitive situation in a straight runway.
    European journal of pharmacology, 1973, Volume: 24, Issue:3

    Topics: Animals; Apomorphine; Chlorpromazine; Competitive Behavior; Dextroamphetamine; Dose-Response Relationship, Drug; Male; Pimozide; Rats; Time Factors

1973
[Antagonism of the effect of dopamine and norepinephrine on some isolated organs].
    Bollettino della Societa italiana di biologia sperimentale, 1973, Jul-15, Volume: 49, Issue:11

    Topics: Animals; Chlorpromazine; Dopamine; Dopamine Antagonists; Drug Antagonism; Haloperidol; Male; Norepinephrine; Phentolamine; Pimozide; Rabbits; Rats; Spleen; Tranquilizing Agents; Vas Deferens

1973
Reversal of reserpine-induced bradykinesia by alpha-methyldopa--new light on its modus operandi.
    Brain research, 1974, May-10, Volume: 71, Issue:1

    Topics: Animals; Carbidopa; Chlorpromazine; Dihydroxyphenylalanine; Disease Models, Animal; Disulfiram; Dose-Response Relationship, Drug; Drug Synergism; Methyldopa; Mice; Movement Disorders; Parkinson Disease; Phenoxybenzamine; Pimozide; Reserpine

1974
[Effect of neuroleptics on the content of dopamine and DOPAC in the caudate nucleus of the rat].
    Experientia, 1974, May-15, Volume: 30, Issue:5

    Topics: Animals; Brain Chemistry; Catechols; Caudate Nucleus; Chlorpromazine; Dopamine; Female; Haloperidol; Male; Methotrimeprazine; Phenylacetates; Pimozide; Rats; Reserpine; Seasons; Tranquilizing Agents

1974
Effects of some psychoactive agents on prolactin secretion in rats of different endocrine states.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1974, Volume: 6, Issue:3

    Topics: Animals; Antidepressive Agents; Castration; Chlorpromazine; Dopamine; Estradiol; Female; Gonadal Steroid Hormones; Injections, Intraperitoneal; Male; Methyltyrosines; Pimozide; Progesterone; Prolactin; Rats; Reserpine; Stimulation, Chemical; Tranquilizing Agents

1974
The dopamine-releasing actions of neuroleptics and ethanol.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 190, Issue:1

    Topics: Animals; Benztropine; Calcium; Caudate Nucleus; Chlorpromazine; Dopamine; Drug Synergism; Ethanol; Haloperidol; In Vitro Techniques; Male; Pimozide; Rats; Reserpine; Synaptosomes; Tranquilizing Agents; Tritium

1974
Modification of striatal acetylcholine concentration by dopamine receptor agonists and antagonists.
    Research communications in chemical pathology and pharmacology, 1974, Volume: 8, Issue:1

    Topics: Acetylcholine; Amphetamine; Animals; Apomorphine; Aromatic Amino Acid Decarboxylase Inhibitors; Brain Chemistry; Brain Stem; Carbidopa; Cerebral Cortex; Chlorpromazine; Corpus Striatum; Dextroamphetamine; Dibenzazepines; Dihydroxyphenylalanine; Dioxoles; Dopamine; Drug Synergism; Haloperidol; Hippocampus; Hypothalamus; Male; Pimozide; Piperazines; Pyrimidines; Rats; Receptors, Drug; Thalamus; Time Factors

1974
Role of noradrenaline in levodopa reversal of reserpine akinesia.
    Brain research, 1974, Sep-13, Volume: 77, Issue:3

    Topics: Animals; Chlorpromazine; Dihydroxyphenylalanine; Haloperidol; Mice; Movement Disorders; Norepinephrine; Phenoxybenzamine; Pimozide; Reserpine

1974
Apomorphine induced biting and fighting behaviour in reserpinized rats and an approach to the mechanism of action.
    Life sciences, 1974, Feb-16, Volume: 14, Issue:4

    Topics: Aggression; Amphetamine; Animals; Apomorphine; Behavior, Animal; Benserazide; Chlorpromazine; Clonidine; Dihydroxyphenylalanine; Dopamine; Humans; Methyltyrosines; Norepinephrine; Phenoxybenzamine; Pimozide; Rats; Receptors, Drug; Reserpine; Thiocarbamates; Time Factors

1974
Inhibition of rat prolactin release by apomorphine in vivo and in vitro.
    Endocrinology, 1974, Volume: 95, Issue:1

    Topics: Animals; Apomorphine; Chlorpromazine; Estrus; Female; In Vitro Techniques; Lactation; Pimozide; Pituitary Gland; Pregnancy; Prolactin; Rats; Receptors, Drug

1974
Acute effects of neuroleptics on brain self-stimulation thresholds in rats.
    Psychopharmacology, 1980, Volume: 67, Issue:1

    Topics: Animals; Antipsychotic Agents; Brain; Chlorpromazine; Clozapine; Haloperidol; Loxapine; Male; Pimozide; Rats; Self Stimulation

1980
Cataleptogenic potency of the antipsychotic drugs is inversely correlated with neuronal activity in the amygdaloid complex of the rat.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:5

    Topics: Action Potentials; Amygdala; Animals; Antipsychotic Agents; Catalepsy; Chlorpromazine; Clozapine; Dose-Response Relationship, Drug; Haloperidol; Humans; Male; Neurons; Pimozide; Rats; Rats, Inbred Strains; Thioridazine

1983
Effects of neuroleptic drugs on brain somatostatin-like-immunoreactivity.
    Neuroscience letters, 1984, Jun-15, Volume: 47, Issue:2

    Topics: Animals; Antipsychotic Agents; Apomorphine; Brain Chemistry; Chlorpromazine; Fluphenazine; Haloperidol; Male; Peptides; Pimozide; Rats; Rats, Inbred Strains; Time Factors

1984
Stimulation of prolactin secretion by neuroleptics in rats with medial basal hypothalamic lesions.
    Neuroendocrinology, 1981, Volume: 32, Issue:6

    Topics: Animals; Antipsychotic Agents; Butaclamol; Chlorpromazine; Female; Hypothalamus; Hypothalamus, Middle; Phentolamine; Pimozide; Prolactin; Rats

1981
Neuroleptic-induced seizures. An in vitro technique for assessing relative risk.
    Archives of general psychiatry, 1982, Volume: 39, Issue:2

    Topics: Animals; Antipsychotic Agents; Butaclamol; Chlorpromazine; Culture Techniques; Dose-Response Relationship, Drug; Fluphenazine; Guinea Pigs; Haloperidol; Hippocampus; Male; Molindone; Pimozide; Seizures; Thioridazine

1982
Role of calmodulin antidiuretic hormone mediated water transport.
    Biochemical and biophysical research communications, 1981, Mar-31, Volume: 99, Issue:2

    Topics: Animals; Biological Transport, Active; Body Water; Bufo marinus; Calcium-Binding Proteins; Calmodulin; Chlorpromazine; Cyclic AMP; Pimozide; Sodium; Trifluoperazine; Urinary Bladder; Vasopressins

1981
The effects of neuroleptics on the GABA receptor of cat primary afferent neurons.
    Brain research, 1981, Oct-05, Volume: 222, Issue:1

    Topics: Afferent Pathways; Animals; Cats; Chlorpromazine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Ganglia, Spinal; Haloperidol; Kinetics; Membrane Potentials; Neurons; Pimozide; Receptors, Cell Surface; Receptors, GABA-A

1981
A calmodulin activated Ca2+-dependent K+ channel in human erythrocyte membrane inside-out vesicles.
    Biochimica et biophysica acta, 1984, Feb-29, Volume: 770, Issue:1

    Topics: Adenosine Triphosphate; Calcium; Calmodulin; Chlorpromazine; Erythrocyte Membrane; Humans; Ion Channels; Kinetics; Pimozide; Potassium; Rubidium

1984
Inhibition of growth and of thymidine incorporation into DNA in Tetrahymena by chlorpromazine, pimozide and penfluridol.
    The Journal of protozoology, 1983, Volume: 30, Issue:2

    Topics: Animals; Chlorpromazine; DNA; Dose-Response Relationship, Drug; Penfluridol; Pimozide; Piperidines; Tetrahymena pyriformis; Thymidine; Thymine Nucleotides

1983
Effects of calmodulin antagonists on immune mouse lymphocytes.
    Molecular pharmacology, 1984, Volume: 26, Issue:2

    Topics: Animals; Calmodulin; Cell Line; Chlorpromazine; Cytotoxicity, Immunologic; Enzyme Inhibitors; Imidazoles; Kinetics; Leukemia, Experimental; Lymphocytes; Mice; Pimozide; Structure-Activity Relationship; Sulfonamides; Trifluoperazine

1984
Ca2+ and calmodulin antagonists inhibit the proton gradients associated with non-cyclic and cyclic photophosphorylation in spinach chloroplasts.
    Biochemical and biophysical research communications, 1982, Dec-31, Volume: 109, Issue:4

    Topics: Calcimycin; Calcium Channel Blockers; Calcium-Binding Proteins; Calmodulin; Chloroplasts; Chlorpromazine; Diuron; Electron Transport; Hydrogen-Ion Concentration; Kinetics; Photophosphorylation; Pimozide; Plants; Trifluoperazine

1982
Acute cocaine intoxication in the conscious dog: studies on the mechanism of lethality.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 217, Issue:2

    Topics: Animals; Blood; Body Temperature; Chlorpromazine; Cocaine; Cold Temperature; Diazepam; Dogs; Female; Hemodynamics; Hydrogen-Ion Concentration; Male; Pancuronium; Pimozide; Propranolol

1981
Trifluoperazine inhibits spreading and migration of cells in culture.
    Journal of cellular physiology, 1981, Volume: 108, Issue:3

    Topics: Animals; Calcium; Calcium-Binding Proteins; Calmodulin; Cell Adhesion; Cell Movement; Cells, Cultured; Chlorpromazine; Fibronectins; Membrane Fluidity; Morphine; Pimozide; Rats; Trifluoperazine

1981
A double-blind controlled study of pimozide versus chlorpromazine in mania.
    Psychopharmacology bulletin, 1980, Volume: 16, Issue:3

    Topics: Bipolar Disorder; Chlorpromazine; Double-Blind Method; Drug Evaluation; Female; Humans; Pimozide

1980
Actions of chlorpromazine, haloperidol and pimozide on lipid metabolism in guinea pig brain slices.
    Biochemical pharmacology, 1980, Oct-01, Volume: 29, Issue:19

    Topics: Animals; Brain; Chlorpromazine; Dopamine; Guinea Pigs; Haloperidol; In Vitro Techniques; Lipid Metabolism; Norepinephrine; Phosphates; Phospholipids; Pimozide

1980
Reserpine abolishes movement-correlated atropine-resistant neocortical low voltage fast activity.
    Brain research, 1980, Nov-24, Volume: 202, Issue:1

    Topics: Animals; Atropine; Cerebral Cortex; Chlorpromazine; Evoked Potentials; Male; Motor Activity; Nialamide; Pimozide; Rats; Reserpine; Trifluoperazine

1980
Characterization of inhibition by haloperidol and chlorpromazine of a voltage-activated K+ current in rat phaeochromocytoma cells.
    British journal of pharmacology, 1995, Volume: 116, Issue:6

    Topics: Animals; Antipsychotic Agents; Barium; Calcium Channels; Calmodulin; Chlorpromazine; Dopamine D2 Receptor Antagonists; Fluspirilene; GTP-Binding Proteins; Haloperidol; Ion Channel Gating; Membrane Potentials; PC12 Cells; Pimozide; Potassium; Potassium Channels; Rats

1995
Effects of drugs on food- and cocaine-maintained responding, III: Dopaminergic antagonists.
    Psychopharmacology, 1996, Volume: 128, Issue:4

    Topics: Animals; Benzazepines; Chlorpromazine; Cocaine; Conditioning, Operant; Dopamine Antagonists; Dopamine Uptake Inhibitors; Food; Macaca mulatta; Male; Narcotics; Pimozide; Self Administration

1996
Pharmacological profile of neuroleptics at human monoamine transporters.
    European journal of pharmacology, 1999, Mar-05, Volume: 368, Issue:2-3

    Topics: Antipsychotic Agents; Carrier Proteins; Cell Line; Chlorpromazine; Cocaine; Dibenzazepines; Dibenzothiepins; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; Humans; Imipramine; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Pimozide; Piperazines; Protein Binding; Radioligand Assay; Recombinant Fusion Proteins; Serotonin Plasma Membrane Transport Proteins; Symporters; Thiazoles; Triflupromazine; Tritium

1999
Dopamine receptor antagonists modulate glucose uptake in rat pheochromocytoma (PC12) cells.
    Neuroscience letters, 1999, Oct-29, Volume: 274, Issue:3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antipsychotic Agents; Benzazepines; Biological Transport; Chlorpromazine; Clozapine; Dizocilpine Maleate; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Excitatory Amino Acid Antagonists; Fluphenazine; Glucose; Haloperidol; PC12 Cells; Pimozide; Rats; Receptors, Dopamine D2; Spiperone; Sulpiride; Tritium

1999
Inhibition of T-cell invasion across cultured fibroblast monolayers by phenothiazine-related calmodulin inhibitors: impairment of lymphocyte motility by trifluoperazine and chlorpromazine, and alteration of the monolayer by pimozide.
    Biochemical pharmacology, 2001, May-15, Volume: 61, Issue:10

    Topics: Animals; Calmodulin; Cell Movement; Cells, Cultured; Chlorpromazine; Dopamine Antagonists; Haloperidol; Humans; Mice; Pimozide; Sulfonamides; T-Lymphocytes; Trifluoperazine; Tumor Cells, Cultured; Vasodilator Agents

2001
Psychotropic drugs interfere with the tight coupling of polyphosphoinositide cycle metabolites in human platelets: a result of receptor-independent drug intercalation in the plasma membrane?
    Biochimica et biophysica acta, 2008, Volume: 1778, Issue:10

    Topics: Antipsychotic Agents; Blood Platelets; Cell Membrane; Chlorpromazine; Clozapine; Dibenzothiazepines; Haloperidol; Humans; Molecular Structure; Phosphatidylinositol Phosphates; Pimozide; Prochlorperazine; Psychotropic Drugs; Quetiapine Fumarate; Signal Transduction; Thrombin; Trifluoperazine

2008
Letter to the Editor: Rethinking The Cost Of Antipsychotic Treatment: The Average Cost Of The Drugs Used In Turkey In 2020.
    Turk psikiyatri dergisi = Turkish journal of psychiatry, 2022,Summer, Volume: 33, Issue:2

    Topics: Adenosine Monophosphate; Adult; Amisulpride; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Chlorpromazine; Clopenthixol; Clozapine; Flupenthixol; Fluphenazine; Haloperidol; Humans; Olanzapine; Paliperidone Palmitate; Pharmaceutical Preparations; Pimozide; Quetiapine Fumarate; Risperidone; Sulpiride; Trifluoperazine

2022