chlorpromazine has been researched along with pimozide in 151 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 111 (73.51) | 18.7374 |
1990's | 13 (8.61) | 18.2507 |
2000's | 16 (10.60) | 29.6817 |
2010's | 10 (6.62) | 24.3611 |
2020's | 1 (0.66) | 2.80 |
Authors | Studies |
---|---|
Ellefson, CR; Kehr, JR; Miller, A; Woo, CM | 1 |
Andrieux, M; Besançon, R; Giros, B; Martres, MP; Pilon, C; Schwartz, JC; Sokoloff, P | 1 |
Bouthenet, ML; Giros, B; Martres, MP; Schwartz, JC; Sokoloff, P | 1 |
Andrews, PR; Craik, DJ; Martin, JL | 1 |
Butler, DE; Marriott, JG; Poschel, BP | 1 |
Choudhary, MS; Craigo, SC; Meltzer, HY; Monsma, FJ; Roth, BL; Shen, Y; Sibley, DR; Uluer, A | 1 |
Emms, F; Freedman, SB; Knowles, MR; Marwood, R; McAllister, G; Patel, S; Seabrook, GR | 1 |
Audinot, V; Chaput, C; Conte, C; Gavaudan, S; Millan, MJ; Newman-Tancredi, A; Touzard, M; Verrièle, L | 1 |
Topliss, JG; Yoshida, F | 1 |
Cavalli, A; De Ponti, F; Poluzzi, E; Recanatini, M | 1 |
Ernsberger, P; Hufeisen, SJ; Jayathilake, K; Kroeze, WK; Meltzer, HY; Popadak, BA; Renock, SM; Roth, BL; Steinberg, S | 1 |
Glennon, RA | 1 |
Keserü, GM | 1 |
Li, J; Rajamani, R; Reynolds, CH; Tounge, BA | 1 |
Nagashima, R; Nishikawa, T; Tobita, M | 1 |
Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
Jia, L; Sun, H | 1 |
Caron, G; Ermondi, G; Visentin, S | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
Ekins, S; Williams, AJ; Xu, JJ | 1 |
Sen, S; Sinha, N | 1 |
Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A | 1 |
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS | 1 |
Bellman, K; Knegtel, RM; Settimo, L | 1 |
Bennis, K; Ducki, S; Lesage, F; Vivier, D | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Friedman, E; Gershon, S; Rotrosen, J | 1 |
Amico, DJ; Calne, DB; Klawans, HL | 1 |
Ahlenius, S; Engel, J | 1 |
Cuparencu, F; Feszt, G; Kun, I; Orbán, I | 1 |
Setler, P; Weidley, E; Zarevics, P | 1 |
Lal, S; Tsang, D | 1 |
Barreca, T; Gallamini, A; Masturzo, P; Murialdo, G; Rolandi, E | 1 |
Munday, KA; Poat, JA; Sumners, C; Woodruff, GN | 1 |
Horita, A; Murray, TF | 1 |
Desiles, M; Puech, AJ; Rips, R | 1 |
Dunlop, RA; Main, CJ; McCreadie, RG | 1 |
Jackson, DM | 1 |
Fogelholm, R; Kotilainen, P; Lamberg, BA; Linnoila, M; Olkinuora, M; Saarinen, P | 1 |
Kuhar, MJ; Rommelspacher, H | 1 |
Beaujouan, JC; Glowinski, J; Guyenet, PG; Javory, AF; Rossier, BJ | 1 |
Calne, DB; Claveria, LE; Haskayne, L; Lodge-Patch, IC; Pallis, CA; Petrie, A; Teychenne, PF | 1 |
Martin, IC | 1 |
Kuschinsky, K | 1 |
Agid, Y; Beaujouan, JC; Glowinski, J; Guyenet, PG; Javoy, F | 1 |
Nose, T; Takemoto, H | 1 |
Costa, E; Guidotti, A; Revuelta, A; Zivkovic, B | 1 |
Dingell, JV; Hill, H; Robinson, SE; Setler, P; Stawarz, RJ; Sulser, F | 1 |
Jones, BE; Risner, ME | 1 |
Cookson, JC; Silverstone, T; Wells, B | 2 |
Baudry, M; Guyon, A; le Sellin, M; Martres, MP; Morgat, JL; Schwartz, JC | 1 |
Cuparencu, B; Feszt, G; Kun, I; Orbán, I | 1 |
Cannon, HE; Gillin, JC; Staub, RA; Wyatt, RJ | 1 |
Gillin, JC; Moja, EA; Stoff, DM; Wyatt, RJ | 1 |
Balakleevskiĭ, AI; Maslova, IV | 1 |
Weick, RF | 1 |
Cicero, TJ; Fuller, T; Mitchell, MV; Olney, JW; Price, MT | 1 |
Anumonye, A; Marinho, AA; Onibuwe-Johnson, T | 1 |
Eliasson, M; Meyerson, BJ | 1 |
Cuparencu, B; Sandor, V | 1 |
Bianchi, S; Consolo, S; Ghezzi, D; Ladinsky, H | 1 |
Miller, RJ | 1 |
Grandison, L; Meites, J | 1 |
Sethy, VH | 1 |
Ferko, AP | 1 |
Baxter, MG; Miller, AA; Wheatley, PL | 1 |
Niemegeers, CJ; Wauquier, A | 1 |
Jones, BE; Risner, M | 1 |
Fielding, S; Lal, H; Marky, M | 1 |
Kelly, PH; Miller, RJ | 1 |
Marsden, CD; Pycock, C; Tarsy, D | 1 |
Manian, AA; Snyder, SH; Yamamura, HI | 1 |
Fillmore, MT; Ruggles, JL; Taukulis, HK | 1 |
Nishizawa, S; Peterson, JW; Shimoyama, I; Uemura, K | 1 |
Miyamoto, K | 1 |
Hall, PF; Papadopoulos, V; Widmaier, EP | 1 |
Chen, DL; Gallicchio, VS; Hait, WN; Lazo, JS | 1 |
Braun, ID; Hait, WN; Kennedy, KA; Lazo, JS; Meandzija, B | 1 |
Brannan, MD; Flaim, SF; Gleason, MM; Muschek, LD; Swigart, SC | 1 |
Chihara, K; Fujita, T; Kaji, H; Kita, T; Kodama, H; Minamitani, N | 1 |
Crow, TJ; Johnson, AL; Johnstone, EC; MacMillan, JF | 1 |
Fujita, M; Horikomi, K | 1 |
Hait, WN; Lee, GL | 1 |
Coulombe, D; Laviolette, P; Miliaressis, E; Philippe, L; Rompre, PP | 1 |
Heyman, GM; Kinzie, DL; Seiden, LS | 1 |
Comar, D; Maziere, M; Turner, JH | 1 |
Barnes, TR; Katona, CL | 1 |
Malmnäs, CO | 1 |
Costa, E; Guidotti, A; Zivkovic, B | 1 |
Clemens, JA; Sawyer, BD; Smalstig, EB | 2 |
Azim, H; Kingstone, E; Kolivakis, T | 1 |
Matthysse, S | 1 |
Everitt, BJ; Fuxe, K; Hökfelt, T | 1 |
Bergmann, F; Chaimovitz, M; Pasternak, V; Ramu, A | 1 |
Andén, NE; Bartholini, G; Corrodi, H; Csillik, B; De Robertis, E; Dresse, A; Fuxe, K; Gerebtzoff, MA; Glowinski, J; Hansson, E; Hökfelt, T; Renson, J; Roos, BE | 1 |
Willems, JL | 1 |
Enero, MA | 1 |
Kapturkiewicz, Z; Maj, J; Sarnek, J | 1 |
Sethy, VH; Van Woert, MH | 2 |
Hatch, RC | 1 |
Ritter, S; Stein, L | 1 |
Corbin, A; Hollingsworth, DR; Mabry, CC; Upton, GV | 1 |
Wurtman, RJ; Yehuda, S | 1 |
Breese, GR; Cooper, BR; Grant, LD | 1 |
Bartholini, G; Keller, HH; Pletscher, A | 1 |
Masur, J; Terada, CW | 1 |
Ferrini, R; Miragoli, G | 1 |
Duvoisin, RC; Marsden, CD | 1 |
Dresse, A; Gérardy, J | 1 |
Clemens, JA; Matsumoto, C; Shaar, CJ; Smalstig, EB | 1 |
Lee, T; Seeman, P | 1 |
Dolphin, A; Duvoisin, RC; Jenner, P; Marsden, CD; Tarsy, D | 1 |
Dandiya, PC; Patni, SK | 1 |
Michael, RP; Schaefer, GJ | 1 |
Cookson, JC | 1 |
Alloway, KD; Bashore, TR; Gelman, J; Rebec, GV | 1 |
Beal, MF; Martin, JB | 1 |
Cheung, CY; Neill, AC; Weiner, RI | 1 |
Luchins, DJ; Oliver, AP; Wyatt, RJ | 1 |
Beauwens, R; Rentmeesters, M | 1 |
Gallagher, JP; Higashi, H; Inanaga, K; Inokuchi, H; Nishi, S | 1 |
Johnson, C; Mitchell, J; Stuckey, M | 1 |
Kristensen, BI; Pape, L | 1 |
Feigenbaum, JJ; Yanai, J | 1 |
Blum, JJ; Keegan, FP | 1 |
Wolberg, G; Zimmerman, TP | 1 |
Annable, L; Chouinard, G | 1 |
Barr, R; Crane, FL | 1 |
Gerber, CJ; Johnson, MH; Roberts, RW; Wilson, LG | 1 |
Allan, T; McClure, DJ; Pecknold, JC; Wrzesinski, L | 1 |
Cookson, J; Silverstone, T; Wells, B | 1 |
Catravas, JD; Waters, IW | 1 |
Brady, RC; Brownstein, BL; Connor, CG | 1 |
Hokin-Neaverson, M | 1 |
Pappas, BA; Vanderwolf, CH | 1 |
Inoue, K; Ito, K; Koizumi, S; Nakazawa, K; Ohno, Y | 1 |
Glowa, JR; Wojnicki, FH | 1 |
Blakely, RD; Jansen, K; Richelson, E; Tatsumi, M | 1 |
Bradley, RJ; Dwyer, DS; Liu, Y | 1 |
De Baetselier, P; De Braekeleer, J; Dewit, J; Grabski, R; Malicka-Blaskiewicz, M; Verschueren, H | 1 |
Lawrie, S; McIntosh, A; Nadeem, Z | 1 |
Lawrie, S; McIntosh, A | 1 |
Balit, CR; Isbister, GK; Kilham, HA | 1 |
Hodneland, E; Holmsen, H; Oruch, R; Pryme, IF | 1 |
Osman, E; Yıldız, M | 1 |
9 review(s) available for chlorpromazine and pimozide
Article | Year |
---|---|
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists | 2003 |
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target?
Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Structure; Neuroprotective Agents; Pain; Potassium Channels, Tandem Pore Domain; Structure-Activity Relationship | 2016 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Short- and long-term regulation of tyrosine hydroxylase.
Topics: Animals; Binding Sites; Brain; Brain Stem; Chlorpromazine; Corpus Striatum; Dibenzothiepins; Dihydroxyphenylalanine; Dopamine; Haloperidol; Hypothalamus; Norepinephrine; Pimozide; Piperazines; Protein Binding; Rats; Reserpine; Sulfides; Time Factors; Tyrosine; Tyrosine 3-Monooxygenase | 1974 |
Psychopharmacological treatment of anorexia nervosa and bulimia. Review and synthesis.
Topics: Adrenocorticotropic Hormone; Anorexia Nervosa; Antidepressive Agents, Tricyclic; Chlorpromazine; Cyproheptadine; Dopamine; Feeding and Eating Disorders; Female; Humans; Hyperphagia; Levodopa; Lithium; Lithium Carbonate; Male; Naloxone; Phenytoin; Pimozide; Serotonin; Zinc | 1983 |
Evidence for the involvement of central dopaminergic receptors in the acute and chronic effects induced by barbiturates.
Topics: Adenylyl Cyclases; Animals; Barbiturates; Brain; Chlorpromazine; Dopamine; Drug Interactions; Drug Tolerance; Female; Haloperidol; Humans; Hydroxydopamines; Mice; Norepinephrine; Oxidopamine; Pimozide; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Receptors, Dopamine; Substance Withdrawal Syndrome | 1983 |
Schizophrenia.
Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clozapine; Cognitive Behavioral Therapy; Dibenzothiepins; Haloperidol; Humans; Olanzapine; Patient Compliance; Perazine; Pimozide; Risperidone; Schizophrenia; Sulpiride | 2003 |
Schizophrenia.
Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clozapine; Haloperidol; Humans; Olanzapine; Patient Compliance; Perazine; Pimozide; Risperidone; Schizophrenia; Sulpiride | 2004 |
Antipsychotic poisoning in young children: a systematic review.
Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Child; Child, Preschool; Chlorpromazine; Clozapine; Dibenzothiazepines; Haloperidol; Humans; Infant; Infant, Newborn; Olanzapine; Pimozide; Piperazines; Poisoning; Quetiapine Fumarate; Quinolones; Risperidone | 2005 |
12 trial(s) available for chlorpromazine and pimozide
Article | Year |
---|---|
Token economy, pimozide and chronic schizophrenia.
Topics: Behavior Therapy; Chlorpromazine; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Hospitals, Psychiatric; Humans; Long-Term Care; Male; Middle Aged; Pimozide; Reward; Schizophrenia; Token Economy | 1978 |
Tardive dyskinesia treated with pimozide.
Topics: Aged; Antipsychotic Agents; Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Consciousness Disorders; Drug Therapy, Combination; Female; Fluphenazine; Humans; Male; Middle Aged; Movement Disorders; Parkinson Disease, Secondary; Perphenazine; Phenothiazines; Pimozide; Prochlorperazine; Promazine; Promethazine; Schizophrenia; Thioridazine | 1975 |
Implications of phenothiazine side effects: a study of antiparkinsonian agents in an older population.
Topics: Adult; Aged; Antipsychotic Agents; Chlorpromazine; Clinical Trials as Topic; Delayed-Action Preparations; Female; Fluphenazine; Haloperidol; Humans; Long-Term Care; Male; Middle Aged; Parkinson Disease; Parkinson Disease, Secondary; Pimozide; Placebos; Schizophrenia; Thioridazine; Trifluoperazine; Trifluperidol | 1975 |
A double-blind controlled study of pimozide vs chlorpromazine in mania.
Topics: Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Double-Blind Method; Humans; Pimozide; Time Factors | 1979 |
Clinical trial of pimozide.
Topics: Adolescent; Adult; Behavior; Chlorpromazine; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Pimozide; Psychiatric Status Rating Scales; Schizophrenia; Time Factors | 1976 |
A randomised controlled trial of prophylactic neuroleptic treatment.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Chlorpromazine; Clinical Trials as Topic; Female; Flupenthixol; Follow-Up Studies; Haloperidol; Humans; Male; Middle Aged; Pimozide; Random Allocation; Recurrence; Schizophrenia; Time Factors; Trifluoperazine | 1986 |
A double-blind comparison of pimozide and chlorpromazine in the maintenance care of chronic schizophrenic outpatients.
Topics: Adolescent; Adult; Ambulatory Care; Chlorpromazine; Chronic Disease; Clinical Trials as Topic; Delayed-Action Preparations; Female; Humans; Male; Middle Aged; Pimozide; Psychiatric Status Rating Scales; Schizophrenia; Time Factors | 1974 |
Post-partum mania, dopamine, and estrogens.
Topics: Affective Disorders, Psychotic; Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Pimozide; Pregnancy; Puerperal Disorders; Receptors, Dopamine | 1982 |
Pimozide in the treatment of newly admitted schizophrenic patients.
Topics: Acute Disease; Adult; Chlorpromazine; Double-Blind Method; Dyskinesia, Drug-Induced; Female; Humans; Male; Middle Aged; Parkinson Disease, Secondary; Pimozide; Prolactin; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology | 1982 |
Pimozide versus chlorpromazine in chronic schizophrenia: a 52 week double-blind study of maintenance therapy.
Topics: Adult; Chlorpromazine; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Pimozide; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Social Adjustment | 1982 |
Comparison of pimozide and chlorpromazine in acute schizophrenia.
Topics: Acute Disease; Adult; Chlorpromazine; Clinical Trials as Topic; Double-Blind Method; Dyskinesia, Drug-Induced; Female; Humans; Male; Middle Aged; Pimozide; Psychiatric Status Rating Scales; Random Allocation; Schizophrenia; Schizophrenic Psychology | 1982 |
Double-blind comparative clinical trial of pimozide and chlorpromazine in mania. A test of the dopamine hypothesis.
Topics: Adult; Affective Disorders, Psychotic; Aged; Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Pimozide; Psychiatric Status Rating Scales; Receptors, Dopamine | 1981 |
130 other study(ies) available for chlorpromazine and pimozide
Article | Year |
---|---|
Synthesis and biological evaluation of some 2-amino-4-aryl-3H-1,5-benzodiazepine analogues of clozapine.
Topics: Adenylyl Cyclase Inhibitors; Animals; Antipsychotic Agents; Avoidance Learning; Brain; Clozapine; Corpus Striatum; Dextroamphetamine; Dibenzazepines; Dopamine; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mice; Rats | 1978 |
Pharmacology of human dopamine D3 receptor expressed in a mammalian cell line: comparison with D2 receptor.
Topics: Animals; Chlorides; CHO Cells; Cricetinae; Dopamine; Dopamine Agents; Dopamine Antagonists; Guanylyl Imidodiphosphate; Humans; Lithium; Lithium Chloride; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D3; Sodium Chloride; Sulpiride; Transfection | 1992 |
Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics.
Topics: Amino Acid Sequence; Animals; Antipsychotic Agents; Base Sequence; Brain Chemistry; Cell Line; Cloning, Molecular; Cricetinae; DNA; DNA Restriction Enzymes; Dopamine; Guanylyl Imidodiphosphate; Molecular Sequence Data; Nucleic Acid Hybridization; Polymerase Chain Reaction; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; RNA, Messenger; Sequence Homology, Nucleic Acid; Tissue Distribution | 1990 |
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Cognition-activating properties of 3-(Aryloxy)pyridines.
Topics: Animals; Cognition; Dose-Response Relationship, Drug; Male; Mice; Psychotropic Drugs; Pyridines; Structure-Activity Relationship | 1981 |
Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors.
Topics: Animals; Antipsychotic Agents; Cell Line; Molecular Structure; Rats; Receptors, Serotonin | 1994 |
Expression and pharmacological characterization of the human D3 dopamine receptor.
Topics: Animals; Binding, Competitive; Cells, Cultured; CHO Cells; Cricetinae; Dopamine; Dopamine Antagonists; GTP-Binding Proteins; Guanine Nucleotides; Humans; Potassium Channels; Rats; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D3; Recombinant Proteins; Second Messenger Systems; Sulpiride | 1994 |
Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35S]GTPgammaS binding study.
Topics: Animals; Antipsychotic Agents; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Sulfur Radioisotopes | 1998 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers.
Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go-Go Potassium Channels; Long QT Syndrome; Models, Molecular; Molecular Conformation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2002 |
H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs.
Topics: Animals; Antipsychotic Agents; Discriminant Analysis; Drug Evaluation, Preclinical; Forecasting; Humans; Protein Binding; Receptors, Histamine H1; Statistics, Nonparametric; Weight Gain | 2003 |
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2003 |
A two-state homology model of the hERG K+ channel: application to ligand binding.
Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Ligands; Models, Biological; Models, Molecular; Potassium Channels, Voltage-Gated; Protein Binding; Protein Conformation | 2005 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
GRIND-based 3D-QSAR and CoMFA to investigate topics dominated by hydrophobic interactions: the case of hERG K+ channel blockers.
Topics: Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Potassium Channel Blockers; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection | 2011 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
MICE models: superior to the HERG model in predicting Torsade de Pointes.
Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
The search for the dopamine receptor: tribulations.
Topics: Chlorpromazine; Dialysis; Dopamine; Fluphenazine; Haloperidol; Hydrogen-Ion Concentration; Membranes, Artificial; Pimozide; Promethazine; Receptors, Drug; Temperature; Time Factors | 1975 |
Altered hypothermic responsivness to (+)-amphetamine.
Topics: Animals; Apomorphine; Body Temperature; Chlorpromazine; Depression, Chemical; Dextroamphetamine; Drug Tolerance; Guinea Pigs; Male; Pimozide | 1976 |
Potentiation by alpha-methyltyrosine of the suppression of food-reinforced lever-pressing behaviour induced by antipsychotic drugs.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Catecholamines; Chlorpromazine; Clozapine; Conditioning, Operant; Drug Synergism; Feeding Behavior; Haloperidol; Male; Methyltyrosines; Phenoxybenzamine; Pimozide; Rats; Receptors, Adrenergic; Thioridazine | 1977 |
The different influence of predominantly antiadrenergic and antidopaminergic neuroleptics on the estrous cycle in rats.
Topics: Animals; Chlorpromazine; Diestrus; Dose-Response Relationship, Drug; Estrus; Female; Fluspirilene; Methotrimeprazine; Phenothiazines; Pimozide; Pregnancy; Pseudopregnancy; Rats; Receptors, Adrenergic; Thioridazine; Tranquilizing Agents | 1977 |
Blockade of intracranial self-stimulation by antipsychotic drugs: failure to correlate with central alpha-noradrenergic blockade.
Topics: Animals; Antipsychotic Agents; Chlorpromazine; Clozapine; Depression, Chemical; Electric Stimulation; Male; Muscle Contraction; Phenoxybenzamine; Pimozide; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Reflex; Self Stimulation; Thioridazine; Time Factors | 1977 |
Effect of monoamine receptor agonists and antagonists on cyclic AMP accumulation in human cerebral cortex slices.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adult; Cerebral Cortex; Child; Chlorpromazine; Cyclic AMP; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Kinetics; Male; Norepinephrine; Phentolamine; Pimozide; Propranolol; Receptors, Adrenergic | 1977 |
[Hyperprolactinemic effect of anti-psychotic drugs].
Topics: Antipsychotic Agents; Chlorpromazine; Female; Haloperidol; Humans; Male; Pimozide; Prolactin; Stimulation, Chemical | 1978 |
The effect of neuroleptic drugs on drinking induced by central administration of angiotensin or carbachol.
Topics: Angiotensin II; Animals; Antipsychotic Agents; Carbachol; Chlorpromazine; Clozapine; Dopamine; Drinking Behavior; Flupenthixol; Fluphenazine; Haloperidol; Injections, Intraperitoneal; Injections, Intraventricular; Male; Pimozide; Rats; Sulpiride | 1979 |
Phencyclidine-induced stereotyped behavior in rats: dose response effects and antagonism by neuroleptics.
Topics: Animals; Antipsychotic Agents; Behavior; Chlorpromazine; Dose-Response Relationship, Drug; Haloperidol; Humans; Male; Motor Activity; Phencyclidine; Pimozide; Rats; Stereotyped Behavior; Time Factors | 1979 |
Is a dopaminergic system involved in thyrotropin releasing hormone induced hyperthermia and in its potentiation by amphetamine?
Topics: alpha-Methyltyrosine; Amphetamine; Animals; Apomorphine; Chlorpromazine; Dopamine; Dopamine Agents; Female; Fever; Haloperidol; Levodopa; Methyltyrosines; Mice; Neurotransmitter Agents; p-Chloroamphetamine; Pimozide; Thyrotropin-Releasing Hormone | 1979 |
Beta-phenylethylamine and locomotor activity in mice. Interaction with catecholaminergic neurones and receptors.
Topics: Animals; Apomorphine; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Catecholamines; Chlorpromazine; Ditiocarb; Drug Interactions; Haloperidol; Male; Methyltyrosines; Mice; Motor Activity; Neurons; Perphenazine; Phenethylamines; Phenoxybenzamine; Phentolamine; Pimozide; Propranolol; Receptors, Drug; Reserpine | 1975 |
The effect of psychotropic drugs on the TSH-response to thyroliberin (TRH).
Topics: Chlorpromazine; Fusaric Acid; Humans; Levodopa; Norepinephrine; Pimozide; Pituitary Gland, Anterior; Propranolol; Psychotropic Drugs; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Thioridazine; Thyrotropin; Thyrotropin-Releasing Hormone | 1977 |
Effects of dopaminergic drugs and acute medial forebrain bundle lesions on striatal acetylcholine levels.
Topics: Acetylcholine; Animals; Antipsychotic Agents; Brain; Chlorpromazine; Corpus Striatum; Haloperidol; Hippocampus; Pimozide; Rats | 1975 |
Effects of dopaminergic receptor agonists and antagonists on the activity of the neo-striatal cholinergic system.
Topics: Acetylcholine; Animals; Apomorphine; Brain Chemistry; Chemistry Techniques, Analytical; Chlorpromazine; Corpus Striatum; Depression, Chemical; Haloperidol; Hippocampus; Hydroxydopamines; Male; Parietal Lobe; Phenothiazines; Pimozide; Rats; Stimulation, Chemical; Tranquilizing Agents | 1975 |
[Cellular effect of neuroleptics].
Topics: Adenylyl Cyclases; Basal Ganglia Diseases; Biological Transport, Active; Catecholamines; Chlorpromazine; Dopamine; Dopamine Antagonists; Histamine H1 Antagonists; Humans; Norepinephrine; Pimozide; Receptors, Drug; Reserpine; Schizophrenia; Serotonin Antagonists; Tranquilizing Agents | 1975 |
Dopamine receptors and cholinergic neurons in the rat neostriatum.
Topics: Acetylcholine; Animals; Apomorphine; Chlorpromazine; Corpus Striatum; Depression, Chemical; Dopamine; Drug Antagonism; Haloperidol; Male; Phenothiazines; Pimozide; Putamen; Rats; Receptors, Drug; Stimulation, Chemical; Substantia Nigra | 1975 |
The effect of penfluridol and some psychotropic drugs on monoamine metabolism in central nervous system.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Brain; Brain Chemistry; Chlordiazepoxide; Chlorpromazine; Diazepam; Dopamine; Haloperidol; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Mice; Norepinephrine; Penfluridol; Pimozide; Piperazines; Piperidines; Psychotropic Drugs; Rats; Serotonin | 1975 |
Effect of thioridazine, clozapine and other antipsychotics on the kinetic state of tyrosine hydroxylase and on the turnover rate of dopamine in striatum and nucleus accumbens.
Topics: Adenylyl Cyclases; Animals; Antipsychotic Agents; Brain; Brain Chemistry; Catecholamines; Chlorpromazine; Clozapine; Corpus Striatum; Dibenzothiepins; Dopamine; Dose-Response Relationship, Drug; Haloperidol; Hypothalamus; Kinetics; Male; Norepinephrine; Pimozide; Promethazine; Rats; Thioridazine; Tyrosine 3-Monooxygenase | 1975 |
On the significance of the increase in homovanillic acid (HVA) caused by antipsychotic drugs in corpus striatum and limbic forebrain.
Topics: Animals; Antipsychotic Agents; Basal Ganglia Diseases; Chlorpromazine; Clozapine; Corpus Striatum; Dextroamphetamine; Dopamine; Dose-Response Relationship, Drug; Haloperidol; Homovanillic Acid; Humans; Limbic System; Male; Phenylacetates; Pimozide; Rats; Receptors, Drug; Rotation; Stereotyped Behavior; Substantia Nigra; Thioridazine | 1975 |
Characteristics of beta-phenethylamine self-administration by dog.
Topics: Animals; Chlorpromazine; Dextroamphetamine; Dogs; Female; Male; Monoamine Oxidase Inhibitors; Motor Activity; Phenethylamines; Phenoxybenzamine; Pimozide; Reinforcement, Psychology; Self Administration | 1977 |
[In vivo binding of tritiated agents in mouse brain].
Topics: Animals; Apomorphine; Brain; Cerebellum; Chlorpromazine; Corpus Striatum; Haloperidol; Male; Mice; Pimozide; Tissue Distribution | 1977 |
Effects of apomorphine combined with chlorpromazine and pimozide on the estrous cycle in rats.
Topics: Animals; Apomorphine; Chlorpromazine; Diestrus; Estrus; Female; Metestrus; Pimozide; Pregnancy; Rats | 1977 |
Paramethoxyphenylethylamine (PMPEA): some behavioral observations in rats.
Topics: Animals; Behavior, Animal; Chlorpromazine; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Humans; Male; Motor Activity; Pimozide; Rats; Reaction Time; Stereotyped Behavior; Tyramine | 1977 |
Neuroleptics attentuate stereotyped behavior induced by beta-phenylethylamine in rats.
Topics: Animals; Behavior; Chlorpromazine; Clozapine; Diazepam; Dose-Response Relationship, Drug; Drug Antagonism; Drug Evaluation; Haloperidol; Humans; Male; Phenethylamines; Pimozide; Rats; Receptors, Dopamine; Stereotyped Behavior; Tranquilizing Agents | 1978 |
[Effect of neuroleptics on acetylcholine metabolism in the basal ganglia of the brain].
Topics: Acetylcholine; Acetylcholinesterase; Animals; Basal Ganglia; Chlorpromazine; Clozapine; Haloperidol; Male; Pimozide; Rats; Tranquilizing Agents | 1978 |
Acute effects of adrenergic receptor blocking drugs and neuroleptic agents on pulsatile discharges of luteinizing hormone in the ovariectomized rat.
Topics: Animals; Castration; Chlorpromazine; Female; Haloperidol; Luteinizing Hormone; Phenoxybenzamine; Phentolamine; Pimozide; Propranolol; Rats; Sympatholytics; Time Factors; Tranquilizing Agents | 1978 |
Luteinizing hormone releasing action of N-methyl aspartate is blocked by GABA or taurine but not by dopamine antagonists.
Topics: Animals; Aspartic Acid; Chlorpromazine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Hypothalamus, Middle; Luteinizing Hormone; Male; Neurosecretion; Pimozide; Rats; Receptors, Dopamine; Taurine | 1978 |
Comparison of the action of lysergic acid diethylamide and apomorphine on the copulatory response in the female rat.
Topics: Animals; Apomorphine; Chlorpromazine; Copulation; Dopamine; Female; Lysergic Acid Diethylamide; Motor Activity; Pimozide; Posture; Rats; Serotonin | 1976 |
Analysis of the mechanism of the protective activity of some sympathomimetic amines in experimental ulcers.
Topics: Amitriptyline; Amphetamine; Animals; Apomorphine; Butyrophenones; Catecholamines; Chlorpromazine; Cocaine; Levodopa; Morphine; Pimozide; Rats; Receptors, Adrenergic; Reserpine; Restraint, Physical; Stomach Ulcer; Sympathomimetics; Trifluperidol | 1977 |
Apparent lack of a dopaminergic-cholinergic link in the rat nucleus accumbens septi-tuberculum olfactorium.
Topics: Acetylcholine; Animals; Apomorphine; Bromocriptine; Chlorpromazine; Clozapine; Dextroamphetamine; Haloperidol; Nucleus Accumbens; Olfactory Bulb; Pimozide; Piribedil; Rats; Receptors, Cholinergic; Receptors, Dopamine; Septal Nuclei | 1977 |
Comparison of the inhibitory effects of neuroleptic drugs on adenylate cyclase in rat tissues stimulated by dopamine, noradrenaline and glucagon.
Topics: Adenylyl Cyclase Inhibitors; Adipose Tissue; Animals; Chlorpromazine; Chlorprothixene; Corpus Striatum; Dopamine; Flupenthixol; Glucagon; Haloperidol; In Vitro Techniques; Liver; Membranes; Norepinephrine; Pimozide; Promazine; Rats; Receptors, Adrenergic; Tranquilizing Agents | 1976 |
Evidence for adrenergic mediation of cholinergic inhibition of prolactin release.
Topics: Animals; Atropine; Atropine Derivatives; Chlorpromazine; Female; Haloperidol; Male; Pilocarpine; Pimozide; Prolactin; Rats; Reserpine; Sex Factors | 1976 |
Effects of chronic treatment with neuroleptics on striatal acetylcholine concentration.
Topics: Acetylcholine; Animals; Chlorpromazine; Corpus Striatum; Haloperidol; Male; Pimozide; Rats; Time Factors; Tranquilizing Agents | 1976 |
The inhibitory action of dopamine on the anterior tibialis muscle preparation antagonized by pimozide and chlorpromazine.
Topics: Animals; Blood Pressure; Cats; Chlorpromazine; Dopamine; Dopamine Antagonists; Drug Interactions; Edrophonium; In Vitro Techniques; Male; Muscle Contraction; Muscles; Phentolamine; Pimozide; Propranolol | 1976 |
Comparative studies on the effects of metoclopramide and some known neuroleptics on the EEG of the conscious rat [proceedings].
Topics: Animals; Chlorpromazine; Dextroamphetamine; Electroencephalography; Haloperidol; Male; Metoclopramide; Pimozide; Rats; Tranquilizing Agents | 1976 |
Restoration of self-stimulation inhibited by neuroleptics.
Topics: Amphetamine; Animals; Apomorphine; Chlorpromazine; Cocaine; Dexetimide; Dopamine Antagonists; Isoquinolines; Male; Pimozide; Rats; Receptors, Dopamine; Self Stimulation; Tranquilizing Agents | 1976 |
Role of noradrenergic and dopaminergic processes in amphetamine self-administration.
Topics: Animals; Chlorpromazine; Dextroamphetamine; Dogs; Dopamine; Female; Male; Methoxamine; Norepinephrine; Phenoxybenzamine; Pimozide; Self Administration | 1976 |
Effect of neuroleptic drugs on mouse jumping induced by L-DOPA in amphetamine treated mice.
Topics: Amphetamine; Animals; Behavior; Chlorpromazine; Clozapine; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Humans; Levodopa; Male; Mice; Pimozide; Promethazine; Psychotropic Drugs; Stereotyped Behavior; Thioridazine; Tranquilizing Agents | 1976 |
The interaction of neuroleptic and muscarinic agents with central dopaminergic systems.
Topics: Adenylyl Cyclase Inhibitors; Animals; Apomorphine; Behavior, Animal; Chlorpromazine; Clopenthixol; Clozapine; Corpus Striatum; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Flupenthixol; Male; Methamphetamine; Models, Biological; Oxotremorine; Parasympathomimetics; Pimozide; Rats; Scopolamine; Substantia Nigra; Thioridazine; Tranquilizing Agents | 1975 |
Inhibition of circling behavior by neuroleptic drugs in mice with unilateral 6-hydroxydopamine lesions of the striatum.
Topics: Animals; Apomorphine; Basal Ganglia Diseases; Behavior; Biogenic Amines; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Chlorpromazine; Clozapine; Corpus Striatum; Dextroamphetamine; Diazepam; Dopamine; Haloperidol; Humans; Hydroxydopamines; Levodopa; Male; Metoclopramide; Mice; Motor Activity; Pentobarbital; Phenoxybenzamine; Pimozide; Promethazine; Stereotyped Behavior; Tranquilizing Agents | 1975 |
Muscarinic cholinergic receptor binding: influence of pimozide and chlorpromazine metabolites.
Topics: Animals; Binding, Competitive; Brain; Chlorpromazine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Pimozide; Rats; Receptors, Cholinergic; Structure-Activity Relationship | 1976 |
Neuroleptic-induced changes in the anxiolytic and myorelaxant properties of diazepam in the rat.
Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Chlorpromazine; Diazepam; Drug Interactions; Haloperidol; Male; Muscle Relaxants, Central; Pimozide; Rats; Thioridazine | 1992 |
Relation between protein kinase C and calmodulin systems in cerebrovascular contraction: investigation of the pathogenesis of vasospasm after subarachnoid hemorrhage.
Topics: Animals; Basilar Artery; Brain; Calmodulin; Chlorpromazine; Dogs; Dose-Response Relationship, Drug; Ischemic Attack, Transient; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Pimozide; Potassium; Protein Kinase C; Signal Transduction; Subarachnoid Hemorrhage; Trifluoperazine; Vasoconstriction | 1992 |
Conditioned drug effects of pimozide, haloperidol and chlorpromazine on methamphetamine-induced behavior.
Topics: Animals; Arousal; Chlorpromazine; Conditioning, Classical; Disease Models, Animal; Dose-Response Relationship, Drug; Haloperidol; Male; Methamphetamine; Motor Activity; Neurocognitive Disorders; Orientation; Pimozide; Rats; Rats, Inbred Strains; Schizophrenic Psychology; Stereotyped Behavior | 1990 |
The role of calmodulin in the responses to adrenocorticotropin of plasma membranes from adrenal cells.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Calmodulin; Cell Membrane; Chlorpromazine; Colforsin; Cyclic AMP; Immunoglobulin G; Mice; Pimozide; Sulfonamides; Trifluoperazine; Tumor Cells, Cultured | 1990 |
Increased lethality of calmodulin antagonists and bleomycin to human bone marrow and bleomycin-resistant malignant cells.
Topics: Bleomycin; Bone Marrow; Bone Marrow Cells; Calmodulin; Cell Survival; Chlorpromazine; Dose-Response Relationship, Drug; Drug Resistance; Drug Synergism; Hematopoietic Stem Cells; Humans; Melitten; Neoplasms, Experimental; Pimozide | 1986 |
Enhanced bleomycin-induced DNA damage and cytotoxicity with calmodulin antagonists.
Topics: Animals; Bleomycin; Calmodulin; Cell Survival; Chlorpromazine; DNA; Drug Synergism; Intercellular Signaling Peptides and Proteins; Leukemia L1210; Melitten; Mice; Peptides; Pimozide; Sulfonamides; Trifluoperazine; Wasp Venoms | 1985 |
Neuroleptic drugs attenuate calcium influx and tension development in rabbit thoracic aorta: effects of pimozide, penfluridol, chlorpromazine, and haloperidol.
Topics: Animals; Antipsychotic Agents; Aorta, Thoracic; Calcium; Calcium Channel Blockers; Chlorpromazine; Haloperidol; In Vitro Techniques; Ion Channels; Male; Muscle Contraction; Penfluridol; Pimozide; Rabbits | 1985 |
Effect of various catecholamine antagonists on prolactin secretion in conscious male rabbits.
Topics: Animals; Antipsychotic Agents; Benzamides; Catecholamines; Chlorpromazine; Consciousness; Haloperidol; Male; Metoprolol; Pimozide; Prazosin; Prolactin; Propranolol; Rabbits; Radioimmunoassay; Yohimbine | 1985 |
[Comparative study of the pharmacological properties of sultopride sulpiride and other antipsychotic drugs: influence of sultopride, sulpiride and other antipsychotic drugs on spontaneous locomotor activity and changes in locomotor activity induced by apo
Topics: Amisulpride; Animals; Antipsychotic Agents; Apomorphine; Chlorpromazine; Clonidine; Drug Interactions; Haloperidol; Imipramine; Male; Mice; Motor Activity; Pimozide; Sulpiride; Yohimbine | 1986 |
Inhibition of growth of C6 astrocytoma cells by inhibitors of calmodulin.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Astrocytoma; Calmodulin; Cell Division; Cell Line; Chlorpromazine; Imidazoles; Melitten; Pimozide; Rats; Structure-Activity Relationship; Trifluoperazine | 1985 |
The curve-shift paradigm in self-stimulation.
Topics: Animals; Brain; Chlorpromazine; Conditioning, Operant; Dose-Response Relationship, Drug; Electric Stimulation; Hypothalamic Area, Lateral; Male; Methocarbamol; Neurons; Pimozide; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Self Stimulation; Synapses | 1986 |
Chlorpromazine and pimozide alter reinforcement efficacy and motor performance.
Topics: Animals; Chlorpromazine; Conditioning, Operant; Male; Pimozide; Psychomotor Performance; Rats; Rats, Inbred Strains; Reinforcement, Psychology | 1986 |
Localization of 11C-radiopharmaceuticals in the Greene melanoma of hamsters.
Topics: Animals; Benzodiazepinones; Carbon Radioisotopes; Chlorpromazine; Cricetinae; Flumazenil; Flunitrazepam; Gallium Radioisotopes; Isotope Labeling; Ketanserin; Melanoma; Mesocricetus; Methionine; Neoplasm Transplantation; Pimozide; Piperidines; Quinuclidinyl Benzilate; Radionuclide Imaging; Tissue Distribution | 1985 |
Susceptibility to drug-induced hypotension in post-partum psychosis.
Topics: Adult; Chlorpromazine; Female; Humans; Hypotension, Orthostatic; Pimozide; Pregnancy; Psychotic Disorders; Psychotropic Drugs; Puerperal Disorders; Thioridazine; Trifluoperazine | 1986 |
Copulatory behavior in the male rat after impaired monoaminergic neurotransmission.
Topics: Adrenalectomy; Adrenergic Agents; Amino Acids; Animals; Castration; Chlorpromazine; Copulation; Depression, Chemical; Disulfides; Dopamine beta-Hydroxylase; Ejaculation; Female; Fenclonine; Imidazoles; Male; Methyltyrosines; Motor Activity; Phenoxybenzamine; Pimozide; Propranolol; Rats; Reserpine; Sexual Behavior, Animal; Stimulation, Chemical; Sympatholytics; Testosterone; Tetrabenazine; Time Factors; Tranquilizing Agents | 1973 |
Antipsychotic drugs stimulate prolactin release.
Topics: Animals; Chlorpromazine; Dopamine; Female; Fluphenazine; Haloperidol; Male; Phenothiazines; Pimozide; Prolactin; Promethazine; Rats; Receptors, Drug; Sex Factors; Stimulation, Chemical; Sulpiride; Thiethylperazine; Thioridazine; Tranquilizing Agents | 1974 |
Dopamine and the pharmacology of schizophrenia: the state of the evidence.
Topics: Amphetamine; Animals; Brain; Cats; Caudate Nucleus; Chlorpromazine; Dogs; Dopamine; Haloperidol; Haplorhini; Humans; Limbic System; Norepinephrine; Pimozide; Psychoses, Substance-Induced; Rats; Receptors, Drug; Schizophrenia; Species Specificity; Stereoisomerism; Stereotyped Behavior; Structure-Activity Relationship; Thiethylperazine; Thioridazine | 1974 |
Inhibitory role of dopamine and 5-hydroxytryptamine in the sexual behaviour of female rats.
Topics: Adrenal Glands; Adrenalectomy; Animals; Castration; Chlorpromazine; Depression, Chemical; Dioxoles; Disulfides; Dopamine Antagonists; Estradiol; Female; Fenclonine; Fenfluramine; Imidazoles; Male; Methyltyrosines; Norepinephrine; Ovary; Pimozide; Piperazines; Progesterone; Rats; Serotonin Antagonists; Sexual Behavior, Animal; Spiperone; Stimulation, Chemical; Time Factors | 1974 |
Compulsive gnawing in rats after implantation of drugs into the ventral thalamus. A contribution to the mechanism of morphine action.
Topics: Amphetamine; Animals; Apomorphine; Brain; Chlorpromazine; Compulsive Behavior; Corpus Striatum; Disulfiram; Dose-Response Relationship, Drug; Drug Synergism; Fenclonine; Haloperidol; Humans; Meperidine; Methadone; Methyldopa; Methyltyrosines; Morphine; Nalorphine; Phenoxybenzamine; Phentolamine; Pimozide; Rats; Thalamus | 1974 |
Histological and molecular biochemistry.
Topics: Animals; Brain; Brain Chemistry; Chlorpromazine; Dopamine; Fluorescence; Haloperidol; Histocytochemistry; Humans; Neurons; Norepinephrine; Pimozide; Receptors, Adrenergic; Receptors, Drug; Reserpine; Serotonin; Synaptic Transmission; Tranquilizing Agents | 1970 |
Dopamine-induced inhibition of synaptic transmission in lumbar paravertebral ganglia of the dog.
Topics: Acetamides; Action Potentials; Animals; Antihypertensive Agents; Apomorphine; Blood Pressure; Butyrophenones; Catecholamines; Chlorpromazine; Dogs; Dopamine; Dose-Response Relationship, Drug; Ergonovine; Ganglia, Spinal; Haloperidol; Isoproterenol; Methane; Norepinephrine; Phenoxybenzamine; Phentolamine; Pimozide; Piperidines; Synapses; Synaptic Transmission; Vasodilator Agents | 1973 |
Proceedings: The role of the presynaptic receptors in regulating noradrenaline overflow by nerve stimulation.
Topics: Animals; Cats; Chlorpromazine; Nictitating Membrane; Norepinephrine; Phenoxybenzamine; Phentolamine; Pimozide; Receptors, Neurotransmitter; Synaptic Transmission | 1973 |
The effect of L-dopa on neuroleptic-induced catalepsy.
Topics: Animals; Catalepsy; Chlorpromazine; Dihydroxyphenylalanine; Fenclonine; Fluphenazine; Humans; Male; Nialamide; Pimozide; Rats; Spiro Compounds; Time Factors; Tranquilizing Agents | 1972 |
Regulation of striatal acetylcholine concentration by dopamine receptors.
Topics: Acetylcholine; Animals; Apomorphine; Brain Chemistry; Carbidopa; Chlorpromazine; Corpus Striatum; Dextroamphetamine; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Haloperidol; Male; Pimozide; Rats; Receptors, Adrenergic | 1974 |
Ketamine catalepsy and anesthesia in dogs pretreated with antiserotonergic or antidopaminergic neuroleptics or with anticholinergic agents.
Topics: Anesthesia; Animals; Atropine; Catalepsy; Chlorpromazine; Dibenzothiepins; Dihydroxyphenylalanine; Dogs; Drug Synergism; Female; Humans; Ketamine; Male; Mecamylamine; Muscle Tonus; Parasympatholytics; Pimozide; Piperazines; Reflex; Respiration; Serotonin Antagonists; Sulfides | 1974 |
Self-stimulation of noradrenergic cell group (A6) in locus coeruleus of rats.
Topics: Animals; Cerebral Ventricles; Chlorpromazine; Conditioning, Operant; Dextroamphetamine; Dose-Response Relationship, Drug; Electrodes, Implanted; Exploratory Behavior; Hypothalamus; Male; Methyltyrosines; Neurons; Norepinephrine; Pimozide; Pons; Rats; Reward; Self Stimulation; Stereotaxic Techniques | 1973 |
Diencephalic involvement in generalized lipodystrophy: rationale and treatment with the neuroleptic agent, pimozide.
Topics: Animals; Child; Chlorpromazine; Cholesterol; Corticotropin-Releasing Hormone; Depression, Chemical; Diencephalon; Female; Gonadotropin-Releasing Hormone; Growth Hormone; Humans; Hydrocortisone; Insulin; Lipids; Lipodystrophy; Liver Function Tests; Male; Pimozide; Rats; Stimulation, Chemical; Time Factors; Triglycerides | 1974 |
The effects of D-amphetamine and related drugs on colonic temperatures of rats kept at various ambient temperatures.
Topics: Animals; Body Temperature; Chemical Precipitation; Chlorpromazine; Colon; Depression, Chemical; Dextroamphetamine; Dose-Response Relationship, Drug; Drug Interactions; Fenfluramine; Injections, Intraperitoneal; Male; Pimozide; Rats; Reserpine; Stimulation, Chemical; Temperature; Time Factors; Tyramine | 1972 |
Comparison of the behavioral depressant effects of biogenic amine depleting and neuroleptic agents following various 6-hydroxydopamine treatments.
Topics: Animals; Behavior, Animal; Brain; Brain Chemistry; Chlorpromazine; Depression, Chemical; Dopamine; Dopamine beta-Hydroxylase; Haloperidol; Hydroxydopamines; Male; Methyltyrosines; Norepinephrine; Pimozide; Rats; Reinforcement, Psychology; Reserpine; Thiazoles; Thiourea; Time Factors; Tranquilizing Agents | 1973 |
Increase of 3-methoxy-4-hydroxyphenylethylene glycol in rat brain by neuroleptic drugs.
Topics: Animals; Brain Chemistry; Chlorpromazine; Dibenzazepines; Dibenzothiepins; Dose-Response Relationship, Drug; Glycols; Haloperidol; Male; Methoxyhydroxyphenylglycol; Pimozide; Piperazines; Rats; Sulfides; Thioridazine; Tranquilizing Agents | 1973 |
Amphetamine- and apomorphine-induced alteration of the behavior of rats submitted to a competitive situation in a straight runway.
Topics: Animals; Apomorphine; Chlorpromazine; Competitive Behavior; Dextroamphetamine; Dose-Response Relationship, Drug; Male; Pimozide; Rats; Time Factors | 1973 |
[Antagonism of the effect of dopamine and norepinephrine on some isolated organs].
Topics: Animals; Chlorpromazine; Dopamine; Dopamine Antagonists; Drug Antagonism; Haloperidol; Male; Norepinephrine; Phentolamine; Pimozide; Rabbits; Rats; Spleen; Tranquilizing Agents; Vas Deferens | 1973 |
Reversal of reserpine-induced bradykinesia by alpha-methyldopa--new light on its modus operandi.
Topics: Animals; Carbidopa; Chlorpromazine; Dihydroxyphenylalanine; Disease Models, Animal; Disulfiram; Dose-Response Relationship, Drug; Drug Synergism; Methyldopa; Mice; Movement Disorders; Parkinson Disease; Phenoxybenzamine; Pimozide; Reserpine | 1974 |
[Effect of neuroleptics on the content of dopamine and DOPAC in the caudate nucleus of the rat].
Topics: Animals; Brain Chemistry; Catechols; Caudate Nucleus; Chlorpromazine; Dopamine; Female; Haloperidol; Male; Methotrimeprazine; Phenylacetates; Pimozide; Rats; Reserpine; Seasons; Tranquilizing Agents | 1974 |
Effects of some psychoactive agents on prolactin secretion in rats of different endocrine states.
Topics: Animals; Antidepressive Agents; Castration; Chlorpromazine; Dopamine; Estradiol; Female; Gonadal Steroid Hormones; Injections, Intraperitoneal; Male; Methyltyrosines; Pimozide; Progesterone; Prolactin; Rats; Reserpine; Stimulation, Chemical; Tranquilizing Agents | 1974 |
The dopamine-releasing actions of neuroleptics and ethanol.
Topics: Animals; Benztropine; Calcium; Caudate Nucleus; Chlorpromazine; Dopamine; Drug Synergism; Ethanol; Haloperidol; In Vitro Techniques; Male; Pimozide; Rats; Reserpine; Synaptosomes; Tranquilizing Agents; Tritium | 1974 |
Modification of striatal acetylcholine concentration by dopamine receptor agonists and antagonists.
Topics: Acetylcholine; Amphetamine; Animals; Apomorphine; Aromatic Amino Acid Decarboxylase Inhibitors; Brain Chemistry; Brain Stem; Carbidopa; Cerebral Cortex; Chlorpromazine; Corpus Striatum; Dextroamphetamine; Dibenzazepines; Dihydroxyphenylalanine; Dioxoles; Dopamine; Drug Synergism; Haloperidol; Hippocampus; Hypothalamus; Male; Pimozide; Piperazines; Pyrimidines; Rats; Receptors, Drug; Thalamus; Time Factors | 1974 |
Role of noradrenaline in levodopa reversal of reserpine akinesia.
Topics: Animals; Chlorpromazine; Dihydroxyphenylalanine; Haloperidol; Mice; Movement Disorders; Norepinephrine; Phenoxybenzamine; Pimozide; Reserpine | 1974 |
Apomorphine induced biting and fighting behaviour in reserpinized rats and an approach to the mechanism of action.
Topics: Aggression; Amphetamine; Animals; Apomorphine; Behavior, Animal; Benserazide; Chlorpromazine; Clonidine; Dihydroxyphenylalanine; Dopamine; Humans; Methyltyrosines; Norepinephrine; Phenoxybenzamine; Pimozide; Rats; Receptors, Drug; Reserpine; Thiocarbamates; Time Factors | 1974 |
Inhibition of rat prolactin release by apomorphine in vivo and in vitro.
Topics: Animals; Apomorphine; Chlorpromazine; Estrus; Female; In Vitro Techniques; Lactation; Pimozide; Pituitary Gland; Pregnancy; Prolactin; Rats; Receptors, Drug | 1974 |
Acute effects of neuroleptics on brain self-stimulation thresholds in rats.
Topics: Animals; Antipsychotic Agents; Brain; Chlorpromazine; Clozapine; Haloperidol; Loxapine; Male; Pimozide; Rats; Self Stimulation | 1980 |
Cataleptogenic potency of the antipsychotic drugs is inversely correlated with neuronal activity in the amygdaloid complex of the rat.
Topics: Action Potentials; Amygdala; Animals; Antipsychotic Agents; Catalepsy; Chlorpromazine; Clozapine; Dose-Response Relationship, Drug; Haloperidol; Humans; Male; Neurons; Pimozide; Rats; Rats, Inbred Strains; Thioridazine | 1983 |
Effects of neuroleptic drugs on brain somatostatin-like-immunoreactivity.
Topics: Animals; Antipsychotic Agents; Apomorphine; Brain Chemistry; Chlorpromazine; Fluphenazine; Haloperidol; Male; Peptides; Pimozide; Rats; Rats, Inbred Strains; Time Factors | 1984 |
Stimulation of prolactin secretion by neuroleptics in rats with medial basal hypothalamic lesions.
Topics: Animals; Antipsychotic Agents; Butaclamol; Chlorpromazine; Female; Hypothalamus; Hypothalamus, Middle; Phentolamine; Pimozide; Prolactin; Rats | 1981 |
Neuroleptic-induced seizures. An in vitro technique for assessing relative risk.
Topics: Animals; Antipsychotic Agents; Butaclamol; Chlorpromazine; Culture Techniques; Dose-Response Relationship, Drug; Fluphenazine; Guinea Pigs; Haloperidol; Hippocampus; Male; Molindone; Pimozide; Seizures; Thioridazine | 1982 |
Role of calmodulin antidiuretic hormone mediated water transport.
Topics: Animals; Biological Transport, Active; Body Water; Bufo marinus; Calcium-Binding Proteins; Calmodulin; Chlorpromazine; Cyclic AMP; Pimozide; Sodium; Trifluoperazine; Urinary Bladder; Vasopressins | 1981 |
The effects of neuroleptics on the GABA receptor of cat primary afferent neurons.
Topics: Afferent Pathways; Animals; Cats; Chlorpromazine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Ganglia, Spinal; Haloperidol; Kinetics; Membrane Potentials; Neurons; Pimozide; Receptors, Cell Surface; Receptors, GABA-A | 1981 |
A calmodulin activated Ca2+-dependent K+ channel in human erythrocyte membrane inside-out vesicles.
Topics: Adenosine Triphosphate; Calcium; Calmodulin; Chlorpromazine; Erythrocyte Membrane; Humans; Ion Channels; Kinetics; Pimozide; Potassium; Rubidium | 1984 |
Inhibition of growth and of thymidine incorporation into DNA in Tetrahymena by chlorpromazine, pimozide and penfluridol.
Topics: Animals; Chlorpromazine; DNA; Dose-Response Relationship, Drug; Penfluridol; Pimozide; Piperidines; Tetrahymena pyriformis; Thymidine; Thymine Nucleotides | 1983 |
Effects of calmodulin antagonists on immune mouse lymphocytes.
Topics: Animals; Calmodulin; Cell Line; Chlorpromazine; Cytotoxicity, Immunologic; Enzyme Inhibitors; Imidazoles; Kinetics; Leukemia, Experimental; Lymphocytes; Mice; Pimozide; Structure-Activity Relationship; Sulfonamides; Trifluoperazine | 1984 |
Ca2+ and calmodulin antagonists inhibit the proton gradients associated with non-cyclic and cyclic photophosphorylation in spinach chloroplasts.
Topics: Calcimycin; Calcium Channel Blockers; Calcium-Binding Proteins; Calmodulin; Chloroplasts; Chlorpromazine; Diuron; Electron Transport; Hydrogen-Ion Concentration; Kinetics; Photophosphorylation; Pimozide; Plants; Trifluoperazine | 1982 |
Acute cocaine intoxication in the conscious dog: studies on the mechanism of lethality.
Topics: Animals; Blood; Body Temperature; Chlorpromazine; Cocaine; Cold Temperature; Diazepam; Dogs; Female; Hemodynamics; Hydrogen-Ion Concentration; Male; Pancuronium; Pimozide; Propranolol | 1981 |
Trifluoperazine inhibits spreading and migration of cells in culture.
Topics: Animals; Calcium; Calcium-Binding Proteins; Calmodulin; Cell Adhesion; Cell Movement; Cells, Cultured; Chlorpromazine; Fibronectins; Membrane Fluidity; Morphine; Pimozide; Rats; Trifluoperazine | 1981 |
A double-blind controlled study of pimozide versus chlorpromazine in mania.
Topics: Bipolar Disorder; Chlorpromazine; Double-Blind Method; Drug Evaluation; Female; Humans; Pimozide | 1980 |
Actions of chlorpromazine, haloperidol and pimozide on lipid metabolism in guinea pig brain slices.
Topics: Animals; Brain; Chlorpromazine; Dopamine; Guinea Pigs; Haloperidol; In Vitro Techniques; Lipid Metabolism; Norepinephrine; Phosphates; Phospholipids; Pimozide | 1980 |
Reserpine abolishes movement-correlated atropine-resistant neocortical low voltage fast activity.
Topics: Animals; Atropine; Cerebral Cortex; Chlorpromazine; Evoked Potentials; Male; Motor Activity; Nialamide; Pimozide; Rats; Reserpine; Trifluoperazine | 1980 |
Characterization of inhibition by haloperidol and chlorpromazine of a voltage-activated K+ current in rat phaeochromocytoma cells.
Topics: Animals; Antipsychotic Agents; Barium; Calcium Channels; Calmodulin; Chlorpromazine; Dopamine D2 Receptor Antagonists; Fluspirilene; GTP-Binding Proteins; Haloperidol; Ion Channel Gating; Membrane Potentials; PC12 Cells; Pimozide; Potassium; Potassium Channels; Rats | 1995 |
Effects of drugs on food- and cocaine-maintained responding, III: Dopaminergic antagonists.
Topics: Animals; Benzazepines; Chlorpromazine; Cocaine; Conditioning, Operant; Dopamine Antagonists; Dopamine Uptake Inhibitors; Food; Macaca mulatta; Male; Narcotics; Pimozide; Self Administration | 1996 |
Pharmacological profile of neuroleptics at human monoamine transporters.
Topics: Antipsychotic Agents; Carrier Proteins; Cell Line; Chlorpromazine; Cocaine; Dibenzazepines; Dibenzothiepins; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; Humans; Imipramine; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Pimozide; Piperazines; Protein Binding; Radioligand Assay; Recombinant Fusion Proteins; Serotonin Plasma Membrane Transport Proteins; Symporters; Thiazoles; Triflupromazine; Tritium | 1999 |
Dopamine receptor antagonists modulate glucose uptake in rat pheochromocytoma (PC12) cells.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antipsychotic Agents; Benzazepines; Biological Transport; Chlorpromazine; Clozapine; Dizocilpine Maleate; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Excitatory Amino Acid Antagonists; Fluphenazine; Glucose; Haloperidol; PC12 Cells; Pimozide; Rats; Receptors, Dopamine D2; Spiperone; Sulpiride; Tritium | 1999 |
Inhibition of T-cell invasion across cultured fibroblast monolayers by phenothiazine-related calmodulin inhibitors: impairment of lymphocyte motility by trifluoperazine and chlorpromazine, and alteration of the monolayer by pimozide.
Topics: Animals; Calmodulin; Cell Movement; Cells, Cultured; Chlorpromazine; Dopamine Antagonists; Haloperidol; Humans; Mice; Pimozide; Sulfonamides; T-Lymphocytes; Trifluoperazine; Tumor Cells, Cultured; Vasodilator Agents | 2001 |
Psychotropic drugs interfere with the tight coupling of polyphosphoinositide cycle metabolites in human platelets: a result of receptor-independent drug intercalation in the plasma membrane?
Topics: Antipsychotic Agents; Blood Platelets; Cell Membrane; Chlorpromazine; Clozapine; Dibenzothiazepines; Haloperidol; Humans; Molecular Structure; Phosphatidylinositol Phosphates; Pimozide; Prochlorperazine; Psychotropic Drugs; Quetiapine Fumarate; Signal Transduction; Thrombin; Trifluoperazine | 2008 |
Letter to the Editor: Rethinking The Cost Of Antipsychotic Treatment: The Average Cost Of The Drugs Used In Turkey In 2020.
Topics: Adenosine Monophosphate; Adult; Amisulpride; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Chlorpromazine; Clopenthixol; Clozapine; Flupenthixol; Fluphenazine; Haloperidol; Humans; Olanzapine; Paliperidone Palmitate; Pharmaceutical Preparations; Pimozide; Quetiapine Fumarate; Risperidone; Sulpiride; Trifluoperazine | 2022 |