chlorpromazine and phenytoin

chlorpromazine has been researched along with phenytoin in 168 studies

Research

Studies (168)

TimeframeStudies, this research(%)All Research%
pre-1990133 (79.17)18.7374
1990's5 (2.98)18.2507
2000's12 (7.14)29.6817
2010's17 (10.12)24.3611
2020's1 (0.60)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Hino, K; Karasawa, T; Masuda, Y; Nagai, Y; Oka, M; Uno, H1
Andrews, PR; Craik, DJ; Martin, JL1
Duffy, EM; Jorgensen, WL1
Topliss, JG; Yoshida, F1
Faller, B; Wohnsland, F1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Caron, G; Ermondi, G1
Abraham, MH; Acree, WE; Ibrahim, A1
Andricopulo, AD; Moda, TL; Montanari, CA1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Gozalbes, R; Pineda-Lucena, A1
Ekins, S; Williams, AJ; Xu, JJ1
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F1
Sen, S; Sinha, N1
Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Steele, DE1
Asboe-Hansen, G2
Hanson, HM; Ivester, CA; Morton, BR1
Anderson, RJ; Raines, A1
Fukuda, H; Kontani, H; Kudo, Y1
Casara, D; Erle, G; Federspil, G; Scandellari, C; Sicolo, N; Zaccaria, M1
Gralla, EJ; Hayden, DW; Mattsson, JL; Sabo, JP; Yochmowitz, MG1
Houghton, GW; Richens, A1
Oettinger, L1
Wada, JA1
Desoize, B; Leger, C; Nahas, GG1
Geary, CG1
Anderson, RJ; Carp, JS2
Kaneyuki, T; Kohsaka, M; Shohmori, T2
Davis, CM; Fenimore, DC; Meyer, CJ1
Diukov, VA1
Hertz, L1
Monroe, RR1
Banna, NR; Kurkjian, R1
Bamonti, F; Dini, M; Jezequel, AM; Koch, M; Orlandi, F1
Gross, MA; Yunis, AA1
Franco, S; Schlosser, W; Sigg, EB; Zavatsky, E1
Anisimov, VN1
McIlwain, H; Pull, I1
Hempel, E; Klinger, G1
Fujii, T; Sato, T; Sugimoto, K; Tamura, A1
Diamond, BI; Hitri, A; Sethi, KD1
Akaike, N; Kaneda, M; Oyama, Y; Wakamori, M1
Fujii, T; Kawase, F; Sato, T; Tamura, A1
Samanin, R; Tullii, M; Vezzani, A; Wu, HQ1
Wickramasinghe, SN1
Abe, K; Kogure, K1
Hanano, M; Iga, T; Sawada, Y; Sugiyama, Y1
Andrews, PR; Lloyd, EJ1
Cardinal, JA; Verbeeck, RK1
Delwiche, F1
Bravo, C; Dávila, L; Espósito Avella, M1
Kutt, H; Penry, JK1
Harpey, JP1
Calcet, J; Corriol, J; Dimov, S; Joanny, P1
Bronaugh, RL; Erwin, VG1
Gogerty, JH; Iorio, LC; Ryan, EA1
Bounameaux, Y1
Afifi, AK; Van Allen, MW1
Levine, RR; Walsh, CT1
Goode, DJ; Meltzer, HY1
Hahn, I; Krieglstein, G; Krieglstein, J; Tschentscher, K1
Bader, H; Wagner, P1
Greengard, P; Quinn, GP; Reid, MB1
Dauby, J; Evraerd, A; Giurgea, C; Moyersoons, F1
Baba, A; Ishii, K; Iwata, H; Matsuda, T; Terashita, Z1
Barron, DI; Hall, GH; Natoff, IL; Vallance, DK1
Mennear, JH; Rudzik, AD1
Amon-Quandt, I; Hüller, H1
Brittain, RT1
Baxter, BL1
Millichap, JG1
Kutt, H; Verebely, K1
Mandel, HG; Riis, M1
Robins, AH1
Izquierdo, I1
Mellor, CS1
Goebel, RW1
Masland, RL; Pippenger, CE; Siris, JH; Werner, WL1
Kamei, C; Shimomura, K; Ueki, S1
Grinberg, KN; Shapiro, IuL; Vaĭntrub, MIa; Zhurkov, VS1
Greene, NM1
Andersen, PR; Gibbs, P; Kubinski, H1
Henry, KR; Willott, J1
Barnett, MP; Blask, DE; Reiter, RJ; Talbot, JA1
Frost, JB1
Nuss, GW; Risley, EA; Van Arman, CG1
Lalla, M; Virolainen, M1
Macri, FJ1
Epstein, JH; Sams, WM1
Viukari, NM1
Krsiak, M; Steinberg, H1
Olds, ME1
Hatch, RC1
Howell, MC; Rever, GW; Rutledge, A; Scholl, ML; Trowbridge, F1
Trautmann, A1
Craddock, G; Fahn, S; Kumin, G1
Girvin, JP; Thurlow, HJ1
Eastham, RD; Jancar, J1
Koe, BK; Weissman, A1
Bhalla, TN; Bhargava, KP; Kohli, RP; Sinha, JN1
Jacobsen, CD1
Andreasen, PB; Heshe, J1
Hata, T; Kita, T; Murakami, T1
von Albert, HH1
Hoshi, A; Kanzawa, F; Kuretani, K1
Calhoun, FJ; Schrogie, JJ; Tolson, WW1
Karler, R; Weinreich, D1
Daughaday, WH; Kipnis, DM; Takahashi, Y1
Jenny, E; Solberg, R1
Zlotlow, M1
Banfi, S; Consonni, P; Diena, A; Pifferi, G1
Dameshek, W1
Goulding, R; Kramer, MD; Monroe, RR; Wise, S1
Hinz, JE; Pisciotta, AV; Ziebert, AP1
Everitt, BJ; Hall, GH; Taylor, EM1
Bartels, E; Rosenberg, P1
Olesen, OV1
Sanders, HD1
Snyder, S1
Benedetti, MS; Dostert, P1
Hiramori, T; Nakao, K; Tagashira, E; Urano, T; Yanaura, S1
Armitage, P; Cohan, SL; Panagakos, J; Raines, A1
Ciofalo, FR1
Johnson, C; Mitchell, J; Stuckey, M1
Herzog, DB1
Cardinal, JA; Verbeeck, RK; Wallace, SM1
Greim, H1
Aihara, H; Araki, H; Ohzeki, M1
Chaput de Saintonge, DM; Hong, CY; Turner, P1
Auchus, AP; Freeman, A; Green, RC1
Balster, RL; Evans, EB1
Chatterjee, A; Mukheree, J1
BERTRAND, I; GAYET-HALLION, T; QUIVY, D1
BOHNER, B; BRATTON, AC; CHEN, G1
HABOVICK, JA; MCCABE, WS1
VANLIERE, EJ1
SIGG, EB; WARNER, CL; YEN, HC1
CHAO, D; DAVIS, SD1
DOAN, CA1
AYCRIGG, JB1
MEYER, HJ; MEYER-BURG, J1
KUEHN, A; SCHALLEK, W; ZABRANSKY, F1
BHARGAVA, KP; BHATTACHARYA, SS; KISHOR, K; SAXENA, PN1
BARSA, JA; SAUNDERS, JC1
ANDERSON, B; BAILEY, G; ROSENBAUM, JM1
WILHOIT, WM1
Duley, L; Henderson-Smart, D1
de Castella, A; Fitzgerald, P; Gilbert, H; Gurvich, C; Kulkarni, J; Marston, N; McCauley-Elsom, K1
Lubszky, S; Reinhart, WH; Schulzki, T; Thöny, S1

Reviews

18 review(s) available for chlorpromazine and phenytoin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Pediatric psychopharmacology. A review with special reference to deanol.
    Diseases of the nervous system, 1977, Volume: 38, Issue:12 Pt 2

    Topics: Adolescent; Adult; Amphetamines; Animals; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity; Carbamazepine; Child; Child, Preschool; Chlorpromazine; Deanol; Epilepsy; Ethanolamines; Heart Rate; Humans; Learning; Methylphenidate; Pemoline; Phenytoin; Rats; Syndrome; Thioridazine

1977
Pharmacological prophylaxis in the kindling model of epilepsy.
    Archives of neurology, 1977, Volume: 34, Issue:7

    Topics: Amygdala; Anesthetics, Local; Animals; Antidepressive Agents, Tricyclic; Atropine; Aziridines; Carbamazepine; Catecholamines; Cats; Cerebral Cortex; Chlorpromazine; Clorazepate Dipotassium; Diazepam; Disease Models, Animal; Drug Evaluation, Preclinical; Epilepsy; Haplorhini; Hydroxydopamines; Phenobarbital; Phenytoin; Rats; Reserpine; Seizures; Valproic Acid

1977
[Pharmacogenetic research in clinical psychiatry].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1976, Volume: 76, Issue:4

    Topics: Antidepressive Agents, Tricyclic; Biotransformation; Bipolar Disorder; Chlorpromazine; Cholinesterases; Drug Hypersensitivity; Enzyme Induction; Glucosephosphate Dehydrogenase Deficiency; Humans; Isoniazid; Liver; Mental Disorders; Microsomes, Liver; Monoamine Oxidase Inhibitors; Pharmacogenetics; Phenytoin; Polymorphism, Genetic; Porphyrias; Psychotropic Drugs

1976
Prediction of the disposition of nine weakly acidic and six weakly basic drugs in humans from pharmacokinetic parameters in rats.
    Journal of pharmacokinetics and biopharmaceutics, 1985, Volume: 13, Issue:5

    Topics: Animals; Antipyrine; Barbiturates; Biological Availability; Chlorpromazine; Diazepam; Drug Evaluation; Female; Half-Life; Humans; Kinetics; Male; Metabolic Clearance Rate; Pentazocine; Pharmaceutical Preparations; Phenylbutazone; Phenytoin; Propranolol; Quinidine; Rats; Species Specificity; Tissue Distribution; Tolbutamide; Valproic Acid; Warfarin

1985
Usefulness of blood levels of antiepileptic drugs.
    Archives of neurology, 1974, Volume: 31, Issue:5

    Topics: Anticonvulsants; Carbamazepine; Chloramphenicol; Chlordiazepoxide; Chlorpromazine; Chromatography, Gas; Dextropropoxyphene; Diazepam; Dicumarol; Disulfiram; Drug Interactions; Epilepsy; Ethosuximide; Humans; Isoniazid; Methylphenidate; Phenethylamines; Phenobarbital; Phenylbutazone; Phenytoin; Primidone; Prochlorperazine; Sulfamethizole; Sulfaphenazole; Thiazines

1974
Lupus-like syndromes induced by drugs.
    Annals of allergy, 1974, Volume: 33, Issue:5

    Topics: Antibodies, Antinuclear; Antibody Formation; Arthritis, Rheumatoid; Chlorpromazine; DNA, Single-Stranded; Drug-Related Side Effects and Adverse Reactions; False Positive Reactions; Female; Fluorescent Antibody Technique; Glucocorticoids; Humans; Hydralazine; Isoantigens; Isoniazid; Lupus Erythematosus, Systemic; Lymphocyte Activation; Male; Neutrophils; Nucleoproteins; Penicillamine; Phenytoin; Procainamide; Remission, Spontaneous; Syphilis Serodiagnosis

1974
[Teratogenic and mutagenic effects of anticonvulsive and psychotropic drugs (review of the literature)].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1972, Volume: 72, Issue:6

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Anticonvulsants; Antidepressive Agents; Arm; Barbiturates; Chlorpromazine; Chromosome Aberrations; Chromosome Disorders; Cricetinae; Drosophila; Female; Heart Defects, Congenital; Humans; Imipramine; Infant, Newborn; Jaundice, Neonatal; Mutagens; Perphenazine; Phenothiazines; Phenytoin; Pregnancy; Primidone; Rabbits; Thalidomide; Tranquilizing Agents; Trifluoperazine

1972
Halothane anesthesia and hepatitis in a high-risk population.
    The New England journal of medicine, 1973, Aug-09, Volume: 289, Issue:6

    Topics: Chemical and Drug Induced Liver Injury; Chlorpromazine; Diazepam; Enzyme Induction; Halothane; Humans; Liver; Microsomes, Liver; Phenobarbital; Phenytoin; Postoperative Complications; Reserpine; Thioridazine; Time Factors

1973
Pharmacology and toxicology of ophthalmic drugs.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1969, Volume: 82, Issue:5

    Topics: Adrenal Cortex Hormones; Animals; Anti-Bacterial Agents; Cats; Chlorpromazine; Ciliary Body; Cornea; Diuretics; Eye; Humans; Interferons; Intraocular Pressure; Iris; Keratoconjunctivitis; Lens, Crystalline; Miotics; Mydriatics; Parasympatholytics; Parasympathomimetics; Pharmacology; Phenytoin; Pupil; Rabbits; Retina; RNA; Sympathomimetics; Toxicology; Wound Healing

1969
Psychopharmacological aspects of aggression: a review of the literature and some new experiments.
    Journal of psychosomatic research, 1969, Volume: 13, Issue:3

    Topics: Aggression; Amobarbital; Animals; Barbiturates; Bees; Behavior, Animal; Cats; Chlordiazepoxide; Chlorpromazine; Escape Reaction; Ethanol; Haplorhini; Humans; Lysergic Acid Diethylamide; Male; Mescaline; Mice; Morphine; Parasympatholytics; Peptides; Phenytoin; Territoriality; Venoms

1969
The interaction of psychopharmacology and psychoanalysis in the borderline patient.
    The Psychiatric quarterly, 1980,Winter, Volume: 52, Issue:4

    Topics: Affect; Anger; Antipsychotic Agents; Borderline Personality Disorder; Chlorpromazine; Clinical Trials as Topic; Depression; Double-Blind Method; Ego; Female; Humans; Imipramine; Lithium; Male; Methods; Personality Disorders; Phenytoin; Procyclidine; Psychoanalytic Interpretation; Tranylcypromine; Trifluoperazine

1980
[Biochemical mechanisms of the hepatotoxicity of psychotropic drugs].
    L'Encephale, 1984, Volume: 10, Issue:5

    Topics: Acute Disease; Anti-Anxiety Agents; Anticonvulsants; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Bilirubin; Butyrophenones; Chemical and Drug Induced Liver Injury; Chlorpromazine; Chronic Disease; Drug Hypersensitivity; Humans; Liver; Monoamine Oxidase Inhibitors; Phenytoin; Psychotropic Drugs; Thioxanthenes

1984
Psychopharmacological treatment of anorexia nervosa and bulimia. Review and synthesis.
    The Journal of nervous and mental disease, 1983, Volume: 171, Issue:9

    Topics: Adrenocorticotropic Hormone; Anorexia Nervosa; Antidepressive Agents, Tricyclic; Chlorpromazine; Cyproheptadine; Dopamine; Feeding and Eating Disorders; Female; Humans; Hyperphagia; Levodopa; Lithium; Lithium Carbonate; Male; Naloxone; Phenytoin; Pimozide; Serotonin; Zinc

1983
Pharmacotherapy of anorexia nervosa and bulimia.
    Pediatric annals, 1984, Volume: 13, Issue:12

    Topics: Amitriptyline; Anorexia Nervosa; Antidepressive Agents, Tricyclic; Chlorpromazine; Clinical Trials as Topic; Clomipramine; Cyproheptadine; Double-Blind Method; Feeding and Eating Disorders; Feeding Behavior; Humans; Hyperphagia; Monoamine Oxidase Inhibitors; Phenytoin; Psychotropic Drugs

1984
[Enzyme induction in the liver changes drug activity].
    Medizinische Klinik, 1980, Sep-26, Volume: 75, Issue:20

    Topics: Animals; Barbiturates; Carbamazepine; Chlorpromazine; Drug Interactions; Enzyme Induction; Glutethimide; Humans; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Pharmaceutical Preparations; Phenylbutazone; Phenytoin; Rifampin; Time Factors

1980
RESISTANCE TO HYPOXIA.
    Archives of internal medicine, 1964, Volume: 113

    Topics: Acclimatization; Blood Transfusion; Chlorpromazine; Dietary Carbohydrates; Endocrine Glands; Enzymes; Humans; Humidity; Hydrogen-Ion Concentration; Hypothermia; Hypoxia; Methylene Blue; Phenytoin; Physical Fitness; Polycythemia; Research; Vitamins

1964
Magnesium sulphate versus phenytoin for eclampsia.
    The Cochrane database of systematic reviews, 2003, Issue:4

    Topics: Anticonvulsants; Chlorpromazine; Drug Combinations; Eclampsia; Female; Humans; Magnesium Sulfate; Meperidine; Phenytoin; Pregnancy; Promethazine; Randomized Controlled Trials as Topic

2003

Trials

4 trial(s) available for chlorpromazine and phenytoin

ArticleYear
Anticonvulsants in the treatment of aggression.
    The Journal of nervous and mental disease, 1975, Volume: 160, Issue:2-1

    Topics: Adult; Aggression; Anticonvulsants; Chlordiazepoxide; Chlorpromazine; Drug Therapy, Combination; Epilepsy; Humans; Impulsive Behavior; Male; Mental Disorders; Neurocognitive Disorders; Phenytoin; Primidone; Schizophrenia; Trifluoperazine; Violence

1975
Diphenylhydantoin as an anticonvulsant: evaluation of treatment in forty mentally subnormal epileptics.
    Journal of mental deficiency research, 1969, Volume: 13, Issue:3

    Topics: Adolescent; Adult; Chlorpromazine; Clinical Trials as Topic; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Humans; Intellectual Disability; Male; Phenytoin; Statistics as Topic

1969
The interaction of psychopharmacology and psychoanalysis in the borderline patient.
    The Psychiatric quarterly, 1980,Winter, Volume: 52, Issue:4

    Topics: Affect; Anger; Antipsychotic Agents; Borderline Personality Disorder; Chlorpromazine; Clinical Trials as Topic; Depression; Double-Blind Method; Ego; Female; Humans; Imipramine; Lithium; Male; Methods; Personality Disorders; Phenytoin; Procyclidine; Psychoanalytic Interpretation; Tranylcypromine; Trifluoperazine

1980
Pharmacotherapy of anorexia nervosa and bulimia.
    Pediatric annals, 1984, Volume: 13, Issue:12

    Topics: Amitriptyline; Anorexia Nervosa; Antidepressive Agents, Tricyclic; Chlorpromazine; Clinical Trials as Topic; Clomipramine; Cyproheptadine; Double-Blind Method; Feeding and Eating Disorders; Feeding Behavior; Humans; Hyperphagia; Monoamine Oxidase Inhibitors; Phenytoin; Psychotropic Drugs

1984

Other Studies

148 other study(ies) available for chlorpromazine and phenytoin

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
A novel class of potential central nervous system agents. 3-Phenyl-2-(1-piperazinyl)-5H-1-benzazepines.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:1

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Benzazepines; Body Temperature Regulation; Brain; Electroshock; Exploratory Behavior; Homovanillic Acid; Hypothermia; Indicators and Reagents; Male; Mice; Mice, Inbred Strains; Piperazines; Rats; Rats, Inbred Strains; Reserpine; Seizures; Structure-Activity Relationship

1988
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
    Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6

    Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water

2001
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:3

    Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization

2008
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution

2011
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk.
    Cardiovascular research, 2011, Jul-01, Volume: 91, Issue:1

    Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Species independence in brain tissue binding using brain homogenates.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
MICE models: superior to the HERG model in predicting Torsade de Pointes.
    Scientific reports, 2013, Volume: 3

    Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes

2013
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Tic doloureux.
    Lancet (London, England), 1975, Aug-30, Volume: 2, Issue:7931

    Topics: Carbamazepine; Chlorpromazine; Humans; Male; Phenytoin; Trigeminal Neuralgia

1975
Treatment of generalized scleroderma: updated results.
    Acta dermato-venereologica, 1979, Volume: 59, Issue:5

    Topics: Chlorpromazine; Collagen; Drug Evaluation; Glutamine; Glycosaminoglycans; Humans; Hydralazine; Levodopa; Penicillamine; Penicillin G; Phenytoin; Prednisone; Scleroderma, Systemic

1979
Nicotine self-administration in rats.
    NIDA research monograph, 1979, Issue:23

    Topics: Amphetamine; Animals; Caffeine; Chlordiazepoxide; Chlorpromazine; Drug Interactions; Drug Tolerance; Ethanol; Humans; Male; Mecamylamine; Nicotine; Pentolinium Tartrate; Phenobarbital; Phenytoin; Rats; Reinforcement, Psychology; Self Administration; Substance-Related Disorders

1979
Suppression of decerebrate rigidity by phenytoin and chlorpromazine.
    Neurology, 1976, Volume: 26, Issue:9

    Topics: Animals; Cats; Chlorpromazine; Decerebrate State; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Muscle Rigidity; Muscle Spindles; Neurons, Afferent; Phenytoin

1976
[Effect of drugs affecting sodium permeability on the muscle spindle of frogs].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1976, Volume: 72, Issue:3

    Topics: Aconitine; Animals; Cell Membrane Permeability; Chlorpromazine; In Vitro Techniques; Muscle Spindles; Neural Conduction; Phenytoin; Polycyclic Compounds; Procaine; Rana catesbeiana; Sodium; Tetrodotoxin; Toxins, Biological; Veratridine

1976
Medical treatment of endogenous organic hyperinsulinism.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1976, Volume: Suppl 6

    Topics: Adenoma, Islet Cell; Adult; Blood Glucose; Child; Chlorpromazine; Diazoxide; Female; Humans; Hyperinsulinism; Male; Pancreatic Diseases; Phenytoin; Propranolol; Streptozocin

1976
The effect of selected drugs on first-stage radioemesis in beagle dogs.
    Radiation research, 1979, Volume: 78, Issue:2

    Topics: Amifostine; Amphetamine; Animals; Antiemetics; Body Weight; Chlorpromazine; Dimenhydrinate; Diphenhydramine; Dogs; Drug Combinations; Perphenazine; Phenytoin; Radiation Injuries, Experimental; Scopolamine; Vomiting; X-Rays

1979
Inhibition of phenytoin metabolism by other drugs used in epilepsy.
    International journal of clinical pharmacology and biopharmacy, 1975, Volume: 12, Issue:1-2

    Topics: Adult; Aged; Chloramphenicol; Chlorpromazine; Depression, Chemical; Drug Interactions; Epilepsy; Half-Life; Humans; Kinetics; Male; Nortriptyline; Phenylbutyrates; Phenytoin; Thiazines; Urea

1975
Effects of psychotropic drugs on DNA synthesis in cultured lymphocytes.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1979, Volume: 160, Issue:3

    Topics: Animals; Cell Membrane Permeability; Chlorpromazine; DNA Replication; Humans; Lymphocytes; Male; Membrane Lipids; Mice; Phenytoin; Psychotropic Drugs; Thymidine

1979
The pathogenesis of aplastic anaemia.
    British journal of hospital medicine, 1979, Volume: 21, Issue:4

    Topics: Adolescent; Anemia, Aplastic; Autoimmune Diseases; Benzene; Child; Chloramphenicol; Chlorpromazine; Female; Gold; Hepatitis, Viral, Human; Humans; Male; Phenytoin

1979
Sensorimotor deficits produced by phenytoin and chlorpromazine in unanesthetized cats.
    Pharmacology, biochemistry, and behavior, 1979, Volume: 10, Issue:4

    Topics: Animals; Behavior, Animal; Cats; Chlorpromazine; Drug Interactions; Female; Male; Motor Skills; Muscles; Phenytoin; Postural Balance; Reflex; Sensory Thresholds

1979
Influences of central acting drugs on delta4-3-ketosteroid 5alpha-oxidoreductase activity in rat diencephalon.
    Folia psychiatrica et neurologica japonica, 1977, Volume: 31, Issue:4

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Animals; Chlorpromazine; Chromatography, Thin Layer; Diencephalon; Imipramine; Male; Oxidoreductases; Phenytoin; Rats

1977
Determination of drugs in plasma by high-performance thin-layer chromatography.
    Clinical chemistry, 1978, Volume: 24, Issue:8

    Topics: Amitriptyline; Chlorpromazine; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Desipramine; Humans; Imipramine; Nortriptyline; Phenobarbital; Phenytoin; Psychotropic Drugs; Spectrophotometry, Ultraviolet

1978
Drug-induced alterations of ion distribution at the cellular level of the central nervous system.
    Pharmacological reviews, 1977, Volume: 29, Issue:1

    Topics: Acetazolamide; Anesthetics, Local; Animals; Barbiturates; Central Nervous System; Chlorpromazine; Ethanol; Extracellular Space; Humans; Ions; Lithium; Magnesium; Neuroglia; Neurons; Ouabain; Phenytoin; Protoveratrines; Pyridines; Tetrodotoxin

1977
The metabolism of testosterone in the brain: the occurrence of delta4-3-ketosteroid 5 alpha-oxidoreductase and 3alpha-hydroxysteroid dehydrogenase and the effects of central acting drugs on these enzyme activities.
    Nihon Naibunpi Gakkai zasshi, 1976, Nov-20, Volume: 52, Issue:11

    Topics: 3-Hydroxysteroid Dehydrogenases; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Animals; Brain; Chlorpromazine; Diencephalon; Imipramine; Male; Microsomes; Oxidoreductases; Phenytoin; Progesterone; Rats

1976
A novel tremorigen antagonized by D-amphetamine.
    Brain research, 1975, Apr-04, Volume: 87, Issue:1

    Topics: Acetates; Aldehydes; Amines; Animals; Atropine; Calcium; Chlorpromazine; Dextroamphetamine; Diazepam; Diphenhydramine; Ganglionic Stimulants; Histidine; Male; Mice; Oximes; Phenoxybenzamine; Phenytoin; Propranolol; Scopolamine; Thiophenes; Tremor; Trimethadione

1975
Hepatic cholesterol synthesis in man: effect of diazepam and other drugs.
    European journal of clinical investigation, 1975, Volume: 5, Issue:2

    Topics: Acetates; Adolescent; Adult; Aged; Animals; Biopsy, Needle; Chlorpromazine; Cholesterol; Diazepam; Female; Humans; Liver; Male; Middle Aged; Phenobarbital; Phenytoin; Rats

1975
Drug-induced inhibition of myeloid colony growth: protective effect of colony-stimulating factor.
    The Journal of laboratory and clinical medicine, 1975, Volume: 86, Issue:3

    Topics: Animals; Bone Marrow; Bone Marrow Cells; Cell Division; Chloramphenicol; Chlorpromazine; Clone Cells; Dose-Response Relationship, Drug; In Vitro Techniques; Leukopenia; Mice; Phenylbutazone; Phenytoin; Tetracycline; Thiamphenicol

1975
Analysis of the action of CNS depressant drugs on somato-somatic reflexes in the cat.
    Neuropharmacology, 1975, Volume: 14, Issue:7

    Topics: Action Potentials; Anesthesia; Animals; Cats; Cerebellum; Chlorpromazine; Diazepam; Female; Male; Neurons, Afferent; Phenobarbital; Phenytoin; Reflex; Synapses

1975
[Pharmacologic study of adrenergic mechanisms of compensatory hypertrophy of the ovary].
    Biulleten' eksperimental'noi biologii i meditsiny, 1975, Volume: 80, Issue:12

    Topics: Animals; Castration; Chlorpromazine; Diethylstilbestrol; Disulfiram; Female; Follicle Stimulating Hormone; Levodopa; Methyldopa; Ovary; Phenytoin; Rats; Sympathetic Nervous System

1975
Centrally-acting drugs and related compounds examined for action on output of adenine derivatives from superfused tissues of the brain.
    Biochemical pharmacology, 1976, Feb-01, Volume: 25, Issue:3

    Topics: Adenine; Adenine Nucleotides; Amobarbital; Animals; Brain; Chlorpromazine; Desipramine; Guinea Pigs; Imipramine; In Vitro Techniques; Lactates; Phenytoin; Psychotropic Drugs

1976
[Influence of neuropharmaca on hormonal contraception].
    Das Deutsche Gesundheitswesen, 1976, Mar-01, Volume: 31, Issue:10

    Topics: Adolescent; Adult; Anticonvulsants; Chlorpromazine; Contraceptives, Oral; Contraceptives, Oral, Hormonal; Drug Synergism; Female; Humans; Menstruation; Menstruation Disturbances; Middle Aged; Phenobarbital; Phenytoin; Pregnancy; Promethazine; Psychotropic Drugs

1976
The effects of haematocrit, plasma protein concentration and temperature of drug-containing blood in-vitro on the concentrations of the drug in the plasma.
    The Journal of pharmacy and pharmacology, 1990, Volume: 42, Issue:8

    Topics: Adult; Blood Preservation; Blood Proteins; Chlorpromazine; Hematocrit; Humans; Phenytoin; Temperature

1990
Phenytoin potentiation of neuroleptic-induced dyskinesias.
    Movement disorders : official journal of the Movement Disorder Society, 1990, Volume: 5, Issue:4

    Topics: Animals; Chlorpromazine; Corpus Striatum; Drug Synergism; Dyskinesia, Drug-Induced; Male; Phenytoin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Stereotyped Behavior

1990
Effects of chlordiazepoxide, chlorpromazine, diazepam, diphenylhydantoin, flunitrazepam and haloperidol on the voltage-dependent sodium current of isolated mammalian brain neurons.
    Brain research, 1989, Aug-14, Volume: 494, Issue:2

    Topics: Animals; Chlordiazepoxide; Chlorpromazine; Diazepam; Flunitrazepam; Haloperidol; Hippocampus; In Vitro Techniques; Membrane Potentials; Phenytoin; Psychotropic Drugs; Rats; Sodium

1989
Binding of chlorpromazine, phenytoin and aspirin to the erythrocytes and lipoproteins in whole human blood.
    The Journal of pharmacy and pharmacology, 1987, Volume: 39, Issue:9

    Topics: Aspirin; Chlorpromazine; Erythrocytes; Humans; Lipoproteins; Phenytoin; Protein Binding; Solubility; Ultracentrifugation

1987
Anticonvulsant drugs effective against human temporal lobe epilepsy prevent seizures but not neurotoxicity induced in rats by quinolinic acid: electroencephalographic, behavioral and histological assessments.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:1

    Topics: Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Chlorpromazine; Diazepam; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Male; Phenobarbital; Phenytoin; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Seizures; Valproic Acid

1986
Evidence of drug metabolism by macrophages: possible role of macrophages in the pathogenesis of drug-induced tissue damage and in the activation of environmental procarcinogens.
    Clinical and laboratory haematology, 1987, Volume: 9, Issue:3

    Topics: Cells; Cells, Cultured; Chlorpromazine; Cytochrome P-450 Enzyme System; Furans; Humans; Inactivation, Metabolic; Macrophages; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Thymidine

1987
Prevention of an increase in susceptibility to calcium in a neuroblastoma cell line.
    Neuroscience letters, 1987, Oct-05, Volume: 80, Issue:3

    Topics: Calcium; Cell Membrane Permeability; Cell Survival; Chlorpromazine; Cold Temperature; Flunarizine; Humans; Neuroblastoma; Pentobarbital; Phenytoin; Tumor Cells, Cultured

1987
A common structural model for central nervous system drugs and their receptors.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:4

    Topics: Amphetamine; Central Nervous System Agents; Chlorpromazine; Imipramine; Models, Molecular; Molecular Conformation; Phenytoin; Procyclidine; Receptors, Drug; Structure-Activity Relationship

1986
Plasma protein binding of salicylic acid, phenytoin, chlorpromazine, propranolol and pethidine using equilibrium dialysis and ultracentrifugation.
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:6

    Topics: Adolescent; Adult; Aged; Blood Proteins; Chlorpromazine; Dialysis; Humans; Lipoproteins; Meperidine; Middle Aged; Phenytoin; Propranolol; Protein Binding; Salicylates; Salicylic Acid; Temperature; Time Factors; Ultracentrifugation

1985
[Iatrogenic coagulopathies].
    Revue medicale de Bruxelles, 1985, Volume: 6, Issue:6

    Topics: Anti-Inflammatory Agents; Asparaginase; Blood Coagulation Disorders; Cephalosporins; Chlorpromazine; Hemophilia A; Humans; Isoniazid; Phenytoin; Sulfonamides

1985
[Interaction of cadmium, diphenylhydantoin and chlorpromazine: their effect in the metabolism of carbohydrates in mice].
    Revista medica de Panama, 1985, Volume: 10, Issue:3

    Topics: Animals; Cadmium; Carbohydrate Metabolism; Chlorpromazine; Drug Interactions; Glucose Tolerance Test; Hyperglycemia; Male; Mice; Phenytoin

1985
The protection against the cerebral and pulmonary effects of hyperbaric oxygen by pharmacological agents and lithium salts in mice.
    Resuscitation, 1973, Volume: 2, Issue:1

    Topics: Acetates; Aminobutyrates; Animals; Anticonvulsants; Antipsychotic Agents; Brain; Chlorpromazine; Female; Hydroxybutyrates; Hyperbaric Oxygenation; Lithium; Lung; Mice; Oxazoles; Phenobarbital; Phenytoin; Prochlorperazine; Promazine; Pulmonary Edema; Seizures; Water

1973
Partial purification and characterization of NADPH-linked aldehyde reductase from monkey brain.
    Journal of neurochemistry, 1973, Volume: 21, Issue:4

    Topics: Acetaldehyde; Alcohol Oxidoreductases; Aldehyde Oxidoreductases; Aldehydes; Ammonium Sulfate; Animals; Barbiturates; Brain; Brain Stem; Calcium Phosphates; Catechols; Centrifugation, Density Gradient; Chemistry Techniques, Analytical; Chlorpromazine; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Gel; Glycols; Haplorhini; Hydroxyindoleacetic Acid; Kinetics; Medulla Oblongata; Mesencephalon; Molecular Weight; NADP; Phenytoin; Pons; Pyrazoles

1973
Anticonvulsant testing with a new analeptic convulsant: N-sulfamoyl-hexahydro-azepine (Sah 41-178).
    Archives internationales de pharmacodynamie et de therapie, 1973, Volume: 206, Issue:2

    Topics: Acetamides; Animals; Anticonvulsants; Azepines; Central Nervous System Stimulants; Chlordiazepoxide; Chlorpromazine; Diazepam; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electroshock; Glutethimide; Haloperidol; Male; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Strychnine; Sulfonamides; Trimethadione

1973
[Studies on the effect of various substances on platelet function with several methods].
    Die Medizinische Welt, 1973, Feb-02, Volume: 24, Issue:5

    Topics: Amphetamine; Anti-Anxiety Agents; Blood Platelets; Caffeine; Chlorpromazine; Debrisoquin; Dibenzazepines; Flurazepam; Guanethidine; Humans; Oxazoles; Papaverine; Phenytoin; Platelet Aggregation; Pyridines; Theophylline

1973
Cerebellar atrophy in epilepsy. Pneumographic and histological documentation of a case with psychosis.
    Journal of neurology, neurosurgery, and psychiatry, 1968, Volume: 31, Issue:2

    Topics: Adult; Brain; Cerebellar Ataxia; Cerebral Ventriculography; Chlorpromazine; Diplopia; Electroconvulsive Therapy; Electroencephalography; Epilepsy, Tonic-Clonic; Facial Muscles; Female; Gait; Humans; Hydantoins; Intellectual Disability; Neurocognitive Disorders; Nystagmus, Pathologic; Phenytoin; Primidone; Psychological Tests; Purkinje Cells; Schizophrenia; Staining and Labeling

1968
Drug absorption in rats pretreated with antibiotics.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 188, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Benzilates; Chlorpromazine; Ileum; Intestinal Absorption; Intestines; Lincomycin; Male; Neomycin; Parasympatholytics; Penicillin V; Phenytoin; Quaternary Ammonium Compounds; Rats; Tetracycline; Time Factors

1974
Cytotoxic effects of imipramine on platelets.
    Biochemical pharmacology, 1974, Sep-15, Volume: 23, Issue:18

    Topics: Animals; Blood Cell Count; Blood Platelets; Calcium Chloride; Chlorpromazine; Creatine Kinase; Edetic Acid; Humans; Imipramine; L-Lactate Dehydrogenase; Magnesium; Male; Ouabain; Phencyclidine; Phenytoin; Rats; Temperature; Thrombin

1974
Distribution of chlorpromazine in a simplified blood influenced by various drugs.
    Naunyn-Schmiedeberg's archives of pharmacology, 1973, Volume: 278, Issue:1

    Topics: Acetazolamide; Animals; Antidepressive Agents; Benzoates; Binding Sites; Binding, Competitive; Cattle; Chlorothiazide; Chlorpromazine; Coumarins; Deoxycholic Acid; Erythrocytes; Fatty Acids; Indomethacin; Phenylbutazone; Phenytoin; Probenecid; Protein Binding; Quinine; Salicylates; Serum Albumin, Bovine; Solubility; Sulfonamides; Suramin; Tetracycline; Thiopental

1973
Proceedings: Effect of alcohols, chlorpromazine and diphenylhydantoin on (Ca2+)-ATPase of human red blood cells.
    Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 282, Issue:Suppl

    Topics: 1-Propanol; Adenosine Triphosphatases; Alcohols; Calcium; Chlorpromazine; Dose-Response Relationship, Drug; Enzyme Activation; Erythrocytes; Ethanol; Humans; In Vitro Techniques; Methanol; Phenytoin

1974
Prevention by antidepressant drugs of reserpine effect on pyridine nucleotide metabolism.
    Molecular pharmacology, 1966, Volume: 2, Issue:4

    Topics: Aminopyrine; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Atropine; Benactyzine; Caffeine; Chlorpheniramine; Chlorpromazine; Female; Hexobarbital; Hydralazine; Hypothalamus; Imipramine; Iproniazid; Isoniazid; Liver; Meprobamate; Methacholine Compounds; Morphine; NAD; Niacinamide; Pargyline; Pentobarbital; Phenylbutazone; Phenytoin; Quinacrine; Rats; Reserpine; Tranylcypromine; Tripelennamine; Zoxazolamine

1966
A particular pharmacological effect on the propagation of experimental strychnine and penicillin epilepsy.
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 179, Issue:2

    Topics: Acetates; Animals; Anticonvulsants; Cerebral Cortex; Chlorpromazine; Electroencephalography; Electroshock; Female; Male; Penicillins; Pentobarbital; Phenobarbital; Phenytoin; Rabbits; Seizures; Sound; Strychnine; Synaptic Transmission

1969
Role of thiamine metabolism in the central nervous system. II. Effects of various agents on thiamine triphosphatase activity in rat brain.
    Japanese journal of pharmacology, 1974, Volume: 24, Issue:6

    Topics: Acetylcholine; Animals; Brain; Chlorpromazine; Colchicine; Fasting; In Vitro Techniques; Insulin; Liver; Male; Methamphetamine; Microsomes; Norepinephrine; Phenytoin; Phosphoric Acids; Phosphoric Monoester Hydrolases; Rats; Reserpine; Thiamine; Thiamine Deficiency; Tyramine

1974
Pharmacological properties of 3-dimethylamino-2-methyl-1-phenyl-1-o-tolylpropanol (SK&F 70463-A).
    The Journal of pharmacy and pharmacology, 1965, Volume: 17, Issue:8

    Topics: Amphetamine; Animals; Anticonvulsants; Cats; Chlorpromazine; Diuretics; Dogs; Haplorhini; Imipramine; Phenytoin; Rats

1965
Antagonism of anticonvulsants by adrenergic blocking agents.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1966, Volume: 122, Issue:1

    Topics: Acetazolamide; Animals; Anticonvulsants; Chlordiazepoxide; Chlorpromazine; Isoproterenol; Mice; Phenoxybenzamine; Phenytoin; Sympatholytics; Tolazoline

1966
[Animal experiment studies on the susceptibility of AH 3 intoxication].
    Das Deutsche Gesundheitswesen, 1966, Jun-23, Volume: 21, Issue:25

    Topics: Animals; Barbiturates; Child; Chlorpromazine; Dogs; Edetic Acid; Female; Guinea Pigs; Histamine H1 Antagonists; Humans; Male; Mice; Phenytoin; Rats; Urethane

1966
The intracerebral effects of noradrenaline and its modification by drugs in the mouse.
    The Journal of pharmacy and pharmacology, 1966, Volume: 18, Issue:9

    Topics: Amitriptyline; Animals; Antidepressive Agents; Ataxia; Atropine; Body Temperature; Brain; Central Nervous System; Chlordiazepoxide; Chlorpheniramine; Chlorpromazine; Diazepam; Drug Antagonism; Haloperidol; Histamine H1 Antagonists; Imipramine; Male; Mice; Norepinephrine; Nortriptyline; Pentobarbital; Phenytoin; Piperazines; Trihexyphenidyl

1966
The effect of selected drugs on the "emotional" behavior elicited via hypothalamic stimulation.
    International journal of neuropharmacology, 1968, Volume: 7, Issue:1

    Topics: Amphetamine; Animals; Atropine; Behavior, Animal; Cats; Chlorpromazine; Depression, Chemical; Electric Stimulation; Emotions; Hypothalamus; Imipramine; Meprobamate; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Pregnanediones; Reserpine; Scopolamine; Stimulation, Chemical; Strychnine; Tremorine

1968
Drugs in management of hyperkinetic and perceptually handicapped children.
    JAMA, 1968, Nov-11, Volume: 206, Issue:7

    Topics: Anticonvulsants; Central Nervous System Stimulants; Child; Child, Preschool; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Epilepsy; Humans; Hyperkinesis; Methylphenidate; Perceptual Disorders; Phenytoin; Primidone; Psychological Tests; Seizures; Tranquilizing Agents

1968
Metabolism of diphenylhydantoin by rat liver microsomes. I. characteristics of the reaction.
    Biochemical pharmacology, 1970, Volume: 19, Issue:3

    Topics: Adenosine Triphosphate; Animals; Azides; Biotransformation; Chlordiazepoxide; Chlorpromazine; Dextropropoxyphene; Diazepam; Diethylstilbestrol; Dimenhydrinate; Disulfiram; Hydantoins; Hydrogen-Ion Concentration; In Vitro Techniques; Isoniazid; Kinetics; Male; Methylene Blue; Microsomes, Liver; NAD; NADP; Oxygen; Phenobarbital; Phenytoin; Proadifen; Prochlorperazine; Rats; Sodium; Temperature

1970
Interference of barbiturates with pyrimidine incorporation. II. Structural specificity of the inhibition of orotate uptake in Bacillus cereus.
    Biochemical pharmacology, 1970, Volume: 19, Issue:6

    Topics: Amobarbital; Bacillus cereus; Barbiturates; Bemegride; Biological Transport; Carbon Isotopes; Carboxylic Acids; Central Nervous System Stimulants; Chemical Phenomena; Chemistry; Chemistry, Physical; Chlorine; Chlorpromazine; Glutethimide; Hexobarbital; Hydantoins; Hydrocarbons, Halogenated; Hydrogen-Ion Concentration; Orotic Acid; Pentobarbital; Phenobarbital; Phenytoin; Primidone; Solubility; Succinimides; Thiopental; Thymine; Trimethadione; Tromethamine; Uracil; Urea

1970
Skin melanin concentrations in schizophrenia.
    The British journal of psychiatry : the journal of mental science, 1972, Volume: 121, Issue:565

    Topics: Adult; Antipsychotic Agents; Chlorpromazine; Chronic Disease; Female; Humans; Male; Melanins; Phenytoin; Schizophrenia; Skin; Spectrophotometry

1972
Effect on pseudoconditioning of drugs with known central nervous activity.
    Psychopharmacologia, 1974, Volume: 38, Issue:3

    Topics: Amobarbital; Animals; Avoidance Learning; Behavior, Animal; Caffeine; Cannabis; Chlorpromazine; Conditioning, Psychological; Depression, Chemical; Diazepam; Dibenzylchlorethamine; Female; Meprobamate; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Rats; Stimulation, Chemical; Strychnine; Trimethadione

1974
Sedation threshold and sedation recovery time in alcoholics.
    Biological psychiatry, 1974, Volume: 9, Issue:2

    Topics: Adult; Alcoholism; Amobarbital; Attention; Chloral Hydrate; Chlorpromazine; Differential Threshold; Drug Tolerance; Humans; Male; Middle Aged; Milieu Therapy; Phenytoin; Problem Solving; Substance Withdrawal Syndrome; Time Factors

1974
Sodium diphenylhydantoin association with oral healing.
    Journal of oral surgery (American Dental Association : 1965), 1972, Volume: 30, Issue:3

    Topics: Alveolectomy; Chlorpromazine; Humans; Phenytoin; Tooth Extraction; Wound Healing

1972
Anticonvulsant drug-serum levels in psychiatric patients with seizure disorders. Effects of certain psychotropic drugs.
    New York state journal of medicine, 1974, Volume: 74, Issue:9

    Topics: Chlorpromazine; Chromatography, Gas; Diazepam; Drug Interactions; Epilepsy; Humans; Mental Disorders; Phenobarbital; Phenytoin; Thioridazine

1974
Significance of withdrawal jumping response in predicting physical dependence in mice.
    Japanese journal of pharmacology, 1973, Volume: 23, Issue:3

    Topics: Amitriptyline; Animals; Atropine; Cannabis; Chlordiazepoxide; Chlorpromazine; Diazepam; Humans; Imipramine; Male; Mephenesin; Methamphetamine; Mice; Morphine Dependence; Naloxone; Pentobarbital; Perphenazine; Phenytoin; Reserpine; Substance Withdrawal Syndrome

1973
Effects of neuropharmacological agents on in vitro formation of complexes between nucleic acids and proteins.
    Neuropharmacology, 1974, Volume: 13, Issue:2

    Topics: Animals; Benztropine; Cattle; Chlorpromazine; Codeine; Desipramine; DNA, Bacterial; Escherichia coli; Histones; Lysergic Acid Diethylamide; Morphine; Neostigmine; Nucleic Acids; Orphenadrine; Phenytoin; Protein Binding; Proteins; RNA, Bacterial; RNA, Ribosomal; Serum Albumin, Bovine; Sodium Dodecyl Sulfate; Trihexyphenidyl

1974
Effects of pharmacological agents on acoustic priming of audiogenic seizures.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1972, Volume: 141, Issue:2

    Topics: Acetates; Aminobutyrates; Animals; Brain Chemistry; Chlorpromazine; Hearing Loss, Noise-Induced; Mice; Mice, Inbred C57BL; Pentobarbital; Phenytoin; Seizures

1972
Nature and the time course of seizures associated with surgical removal of the pineal gland from parathyroidectomized rats.
    Experimental neurology, 1973, Volume: 38, Issue:3

    Topics: Animals; Chlordiazepoxide; Chlorpromazine; Diazepam; Haloperidol; Male; Parathyroid Glands; Phenytoin; Pineal Gland; Rats; Seizures; Time Factors

1973
Mesoridazine and chlorpromazine in the treatment of alcohol withdrawal syndrome.
    Canadian Psychiatric Association journal, 1973, Volume: 18, Issue:5

    Topics: Administration, Oral; Alcoholism; Chlorpromazine; Female; Humans; Injections, Intramuscular; Male; Mesoridazine; Phenytoin; Psychiatric Status Rating Scales; Substance Withdrawal Syndrome; Vitamins

1973
Interactions of aspirin, indomethacin and other drugs in adjuvant-induced arthritis in the rat.
    The Journal of pharmacology and experimental therapeutics, 1973, Volume: 187, Issue:2

    Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Body Weight; Chlorpromazine; Cyclophosphamide; Dexamethasone; Dose-Response Relationship, Drug; Drug Interactions; Hydrocortisone; Indomethacin; Male; Mycobacterium; Phenytoin; Prednisolone; Rats; Salicylates; Spironolactone; Time Factors

1973
Blood lymphoblast proliferation in vivo in cutaneous drug hypersensitivity reactions.
    International archives of allergy and applied immunology, 1974, Volume: 46, Issue:2

    Topics: Blood Cell Count; Carbamazepine; Chlorpromazine; Drug Hypersensitivity; Exanthema; Humans; Lymphocytes; Nitrofurantoin; Phenytoin; Prednisone; Stevens-Johnson Syndrome; Sulfonamides; Thymidine; Trimethoprim; Tritium; Urticaria

1974
The experimental production of drug phototoxicity in guinea pigs. I. Using sunlight.
    The Journal of investigative dermatology, 1967, Volume: 48, Issue:1

    Topics: Animals; Chlorothiazide; Chlorpromazine; Demeclocycline; Diphenhydramine; Guinea Pigs; Phenytoin; Photosensitivity Disorders; Plastics; Skin; Sunlight; Tetracycline

1967
Comparative effects of amphetamine, scopolamine and chlordiazepoxide on self-stimulation behavior.
    Revue canadienne de biologie, 1972, Volume: 31

    Topics: Amphetamine; Animals; Brain; Chlordiazepoxide; Chlorpromazine; Conditioning, Operant; Depression, Chemical; Drug Interactions; Electric Stimulation; Extinction, Psychological; Hypothalamus; Male; Phenytoin; Physostigmine; Rats; Reinforcement Schedule; Reward; Scopolamine; Self Stimulation; Stimulation, Chemical; Tetrabenazine

1972
Effect of drugs on catnip (Nepeta cataria)-induced pleasure behavior in cats.
    American journal of veterinary research, 1972, Volume: 33, Issue:1

    Topics: Amphetamine; Animals; Atropine; Behavior, Animal; Cats; Chlorpheniramine; Chlorpromazine; Drug Synergism; Female; Hexamethonium Compounds; Histidine; Lactones; Magnoliopsida; Male; Mecamylamine; Methysergide; Morphine; Neostigmine; Phenytoin; Physostigmine; Pilocarpine; Plant Extracts; Propranolol; Pyrans; Salivation; Serotonin; Sexual Behavior, Animal

1972
Hyperactivity in children: types, diagosis, drug therapy, approaches to management.
    Clinical pediatrics, 1972, Volume: 11, Issue:1

    Topics: Amphetamine; Anxiety; Attention; Attention Deficit Disorder with Hyperactivity; Brain Damage, Chronic; Child; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Diazepam; Environment; Family; Female; Humans; Hyperkinesis; Methylphenidate; Motor Skills; Phenytoin; Thioridazine

1972
[Dialysis of drugs and poisons. 2].
    Medizinische Klinik, 1972, Nov-03, Volume: 67, Issue:44

    Topics: Acetaminophen; Aminopyrine; Amitriptyline; Aspirin; Carbamazepine; Chlordiazepoxide; Chlorpromazine; Dextropropoxyphene; Diazepam; Heroin; Humans; Imipramine; Lithium; Pargyline; Pentazocine; Phenacetin; Phenelzine; Phenytoin; Poisoning; Primidone; Promazine; Renal Dialysis; Salicylates; Tranylcypromine; Trifluoperazine

1972
Acute toxic psychosis from suicidal overdosage of amantadine.
    Archives of neurology, 1971, Volume: 25, Issue:1

    Topics: Acute Disease; Amantadine; Blood-Brain Barrier; Chlorpromazine; Humans; Male; Middle Aged; Parkinson Disease, Postencephalitic; Phenytoin; Psychoses, Substance-Induced; Suicide; Sympathetic Nervous System

1971
Use of anti-epileptic medication in treating "flashbacks" from hallucinogenic drugs.
    Canadian Medical Association journal, 1971, Volume: 105, Issue:9

    Topics: Adult; Chlorpromazine; Female; Hallucinations; Humans; Lysergic Acid Diethylamide; Phenytoin

1971
Macrocytosis associated with anticonvulsant therapy.
    Epilepsia, 1970, Volume: 11, Issue:3

    Topics: Adult; Aged; Amobarbital; Anticonvulsants; Chlorpromazine; Humans; Phenytoin

1970
m-Fluorotyrosine convulsions and mortality: relationship to catecholamine and citrate metabolism.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 155, Issue:1

    Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Anticonvulsants; Atropine; Azoles; Brain; Chlordiazepoxide; Chlorpromazine; Citrates; Dihydroxyphenylalanine; Disulfiram; Drug Antagonism; Drug Synergism; Kidney; Lysergic Acid Diethylamide; Male; Methyldopa; Mice; Morphine; Nialamide; Norepinephrine; Pargyline; Phenobarbital; Phenytoin; Reserpine; Seizures; Serotonin; Strychnine; Tetrabenazine; Trimethadione; Tyrosine; Urea

1967
Aconitine-induced writhing: a method for assessment of analgesic activity.
    Japanese journal of pharmacology, 1969, Volume: 19, Issue:1

    Topics: Aconitum; Analgesics; Animals; Aspirin; Behavior, Animal; Chlorpromazine; Imipramine; Mephenesin; Methaqualone; Methods; Mice; Morphine; Phenoxybenzamine; Phenylbutazone; Phenytoin; Sodium Salicylate

1969
[Drug-induced anemias].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1970, Dec-15, Volume: 90, Issue:24

    Topics: Adrenal Cortex Hormones; Anemia; Barbiturates; Bone Marrow; Chloramphenicol; Chlorpromazine; Dihydroxyphenylalanine; Gastrointestinal Hemorrhage; Gold; Humans; Hypoglycemic Agents; Indomethacin; Isoniazid; Nitrofurantoin; Phenacetin; Phenylbutazone; Phenytoin; Quinidine; Quinine; Salicylates; Sulfonamides

1970
[Neuropsychiatric manifestations of systemic lupus erythematosus].
    Nordisk psykiatrisk tidsskrift. Nordic journal of psychiatry, 1969, Volume: 23, Issue:5

    Topics: Adult; Chlorpromazine; Chlorprothixene; Female; Humans; Lupus Erythematosus, Systemic; Neurologic Manifestations; Phenytoin; Psychoses, Substance-Induced; Psychotic Disorders; Time Factors

1969
[Introduction of mass psychology of animals to pharmacology. 2. New screening method of drugs acting on the central nervous system].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1969, Jul-20, Volume: 65, Issue:4

    Topics: Aminobutyrates; Amphetamine; Animals; Anticonvulsants; Behavior, Animal; Carbamates; Chlordiazepoxide; Chlorpromazine; Diphenhydramine; Imidazoles; Imipramine; Male; Mice; Phenobarbital; Phenytoin; Reserpine; Tranquilizing Agents

1969
[Detection of sedative effect by electronystagmography].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:9

    Topics: Amphetamine; Antihypertensive Agents; Caffeine; Chlorpromazine; Dibenzazepines; Electric Stimulation; Humans; Hypnotics and Sedatives; Imidazoles; Methods; Pentobarbital; Phenmetrazine; Phenothiazines; Phenytoin; Promethazine; Thiethylperazine; Vestibular Function Tests

1969
Relationship between antitumor activity and chemical structure in psychotropic agents.
    Gan, 1970, Volume: 61, Issue:6

    Topics: Amitriptyline; Animals; Antidepressive Agents; Antineoplastic Agents; Benactyzine; Biperiden; Chemical Phenomena; Chemistry; Chlordiazepoxide; Chlorpromazine; Chlorprothixene; Cyclophosphamide; Diazepam; Phenytoin

1970
Effects of various drugs on the uterotropic response to mestranol and norethynodrel in the rat.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1971, Volume: 136, Issue:1

    Topics: Aminosalicylic Acids; Animals; Chlorpromazine; Drug Synergism; Female; Imipramine; Mestranol; Norethynodrel; Organ Size; Phenobarbital; Phenylbutazone; Phenytoin; Proadifen; Rats; Scopolamine; Tolbutamide; Uterus

1971
Interaction of ouabain and diphenylhydantoin on oxygen consumption in rats.
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 190, Issue:2

    Topics: Animals; Chlorpromazine; Depression, Chemical; Drug Antagonism; Ouabain; Oxygen Consumption; Phenytoin; Puromycin; Rats; Time Factors

1971
Growth hormone secretion during sleep.
    The Journal of clinical investigation, 1968, Volume: 47, Issue:9

    Topics: Adult; Blood Glucose; Chlordiazepoxide; Chlorpromazine; Electroencephalography; Eye Movements; Female; Growth Hormone; Humans; Hydrocortisone; Imipramine; Insulin; Isocarboxazid; Male; Phenobarbital; Phenytoin; Secretory Rate; Sleep

1968
[Pharmacologic properties of partially purified glutamic acid decarboxylase (L-glutamate-1-carboxylyase, E.C. 4.1.1.15) from calf cerebral cortex].
    Helvetica physiologica et pharmacologica acta, 1968, Volume: 26, Issue:3

    Topics: Animals; Antidepressive Agents; Barbiturates; Carboxy-Lyases; Cattle; Cerebral Cortex; Chemical Phenomena; Chemistry; Chlorpromazine; Codeine; Glutamates; Hydantoins; Imipramine; Lysergic Acid Diethylamide; Phenethylamines; Phenytoin; Primidone; Psilocybin; Pyrrolidines; Spectrophotometry

1968
Temporal lobe "spike focus" associated with confusion, complete amnesia and fugues in a paranoid schizophrenic.
    The Psychiatric quarterly, 1968, Volume: 42, Issue:4

    Topics: Adult; Amnesia; Chlorpromazine; Cognition Disorders; Dissociative Disorders; Electroencephalography; Epilepsy, Temporal Lobe; Humans; Male; Paranoid Disorders; Phenobarbital; Phenytoin; Schizophrenia; Time Factors; Trifluoperazine

1968
2,3-benzoxazines. IX. Synthesis and central nervous system depressant activity of some 3,6- and 3,7-disubstituted 1H-3,4-dihydro-2,3-benzoxazines.
    Journal of medicinal chemistry, 1969, Volume: 12, Issue:2

    Topics: Analgesia; Animals; Aspirin; Ataxia; Barbiturates; Central Nervous System; Chlordiazepoxide; Chlorpromazine; Exploratory Behavior; Male; Meprobamate; Mice; Morphine; Motor Activity; Muscles; Oxazines; Phenytoin; Pyridones; Rats; Reflex; Seizures

1969
Chloramphenicol aplastic anemia in identical twins--a clue to pathogenesis.
    The New England journal of medicine, 1969, Jul-03, Volume: 281, Issue:1

    Topics: Anemia, Aplastic; Bone Marrow; Bone Marrow Cells; Chloramphenicol; Chlorpromazine; Diseases in Twins; DNA; Glucosephosphate Dehydrogenase Deficiency; Humans; Pharmacogenetics; Phenytoin

1969
EFG activation of patients receiving phenothiazines and chlordiazepoxide.
    The Journal of nervous and mental disease, 1965, Volume: 141, Issue:1

    Topics: Adult; Anxiety; Cerebral Cortex; Chloralose; Chlordiazepoxide; Chlorpromazine; Depression; Electroencephalography; Epilepsy; Female; Humans; Male; Middle Aged; Phenothiazines; Phenytoin; Schizophrenia; Trifluoperazine

1965
Effect of chlorpromazine on DNA synthesis in a cell free system.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1965, Volume: 120, Issue:2

    Topics: Aminopyrine; Animals; Aspirin; Chlorpromazine; Diphenhydramine; DNA; In Vitro Techniques; Liver; Liver Regeneration; Phenytoin; Rats; Subcellular Fractions; Thioridazine; Thymidine

1965
The sedative and anticonvulsant activity of some substituted pyrrolidones and piperidones.
    British journal of pharmacology and chemotherapy, 1965, Volume: 25, Issue:3

    Topics: Animals; Behavior, Animal; Cats; Chlorpromazine; Dogs; Female; Glutethimide; Guinea Pigs; Male; Meprobamate; Mice; Phenobarbital; Phenytoin; Piperidines; Pyrrolidinones; Rabbits; Rats

1965
Drug effects on the spontaneous electrical activity of the squid giant axon.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 155, Issue:3

    Topics: Acetylcholine; Action Potentials; Animals; Anticonvulsants; Atropine; Axons; Barbiturates; Bromides; Chloroform; Chlorpheniramine; Chlorpromazine; Curare; Dopamine; Electrophysiology; Ethanol; Ethers; Evoked Potentials; Hydantoins; Mollusca; Muscles; Nortropanes; Parasympatholytics; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Procaine; Serotonin; Strychnine; Tetracaine; Tremorine; Trihexyphenidyl; Trimethadione

1967
The influence of disulfiram and calcium carbimide on the serum diphenylhydantoin. Excretion of HPPH in the urine.
    Archives of neurology, 1967, Volume: 16, Issue:6

    Topics: Acetazolamide; Adult; Aged; Alcoholism; Amitriptyline; Chlordiazepoxide; Chlorpromazine; Chromatography, Thin Layer; Cyanates; Disulfiram; Drug Synergism; Epilepsy; Humans; Hydroflumethiazide; Imipramine; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone

1967
A comparison of the convulsant activity of procaine and pentylenetetrazol.
    Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 170, Issue:1

    Topics: Animals; Anticonvulsants; Chlorpromazine; Dibenzylchlorethamine; Female; Hydroxybutyrates; Mice; Pentobarbital; Pentylenetetrazole; Phenobarbital; Phenytoin; Procaine; Reflex; Reserpine; Seizures

1967
Participant of serotonin turnover rate in the brain on barbital withdrawal convulsion.
    Japanese journal of pharmacology, 1982, Volume: 32, Issue:1

    Topics: Animals; Barbital; Barbiturates; Brain; Chlorpromazine; Humans; Hydroxyindoleacetic Acid; Male; Nitrazepam; Phenytoin; Rats; Rats, Inbred Strains; Seizures; Serotonin; Substance Withdrawal Syndrome

1982
Phenytoin and chlorpromazine in the treatment of spasticity.
    Archives of neurology, 1980, Volume: 37, Issue:6

    Topics: Adult; Aged; Chlorpromazine; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Motor Neurons; Muscle Spasticity; Muscle Tonus; Phenytoin; Synaptic Transmission

1980
Modification of spinal cord transmission by an interaction of chlorpromazine and phenytoin.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 216, Issue:2

    Topics: Animals; Cats; Chlorpromazine; Cordotomy; Drug Interactions; Female; Male; Phenytoin; Spinal Cord; Synaptic Transmission

1981
Effects of some membrane perturbers on alpha 1-adrenergic receptor binding.
    Neuroscience letters, 1981, Feb-06, Volume: 21, Issue:3

    Topics: Animals; Cattle; Cerebral Cortex; Chlorpromazine; Dibucaine; Dioxanes; Lidocaine; Membranes; Mepivacaine; Phenytoin; Procainamide; Procaine; Propranolol; Quinidine; Receptors, Adrenergic; Receptors, Adrenergic, alpha

1981
Effect of age and sex on the plasma binding of acidic and basic drugs.
    European journal of clinical pharmacology, 1984, Volume: 27, Issue:1

    Topics: Adolescent; Adult; Age Factors; Aged; Blood Proteins; Chlorpromazine; Desipramine; Female; Humans; Male; Meperidine; Middle Aged; Pharmaceutical Preparations; Phenytoin; Propranolol; Protein Binding; Salicylates; Salicylic Acid; Serum Albumin; Sex Factors

1984
Treatment of generalized scleroderma with inhibitors of collagen synthesis.
    International journal of dermatology, 1982, Volume: 21, Issue:3

    Topics: Catechin; Chlorpromazine; Collagen; Dextrothyroxine; Glutamine; Humans; Hydralazine; Levodopa; Penicillamine; Penicillin G; Phenytoin; Prednisone; Scleroderma, Systemic

1982
Hippocampal kindling and effects of antiepileptic drugs.
    Japanese journal of pharmacology, 1982, Volume: 32, Issue:1

    Topics: Amitriptyline; Amygdala; Animals; Anticonvulsants; Chlorpromazine; Diazepam; Electric Stimulation; Electroencephalography; Hippocampus; Kindling, Neurologic; Male; Phenytoin; Rats; Rats, Inbred Strains; Seizures

1982
Effects of chlorpromazine and other drugs acting on the central nervous system on human sperm motility.
    European journal of clinical pharmacology, 1982, Volume: 22, Issue:5

    Topics: Caffeine; Central Nervous System; Chlorpromazine; Diazepam; Humans; In Vitro Techniques; Male; Phenobarbital; Phenytoin; Sperm Motility

1982
Agitated behavior relieved following treatment of cervical dystonia in dementia.
    Neurology, 1995, Volume: 45, Issue:2

    Topics: Alzheimer Disease; Botulinum Toxins; Chlorpromazine; Dystonia; Female; Humans; Isoxazoles; Middle Aged; Neck Muscles; Phenytoin; Piperidines; Risperidone; Valproic Acid

1995
Inhaled 1,1,1-trichloroethane-produced physical dependence in mice: effects of drugs and vapors on withdrawal.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:2

    Topics: Administration, Inhalation; Animals; Chlorpromazine; Ethanol; Male; Mice; Midazolam; Pentobarbital; Phenytoin; Substance Withdrawal Syndrome; Substance-Related Disorders; Toluene; Trichloroethanes; Volatilization

1993
Comparative study of different anticonvulsants in eclampsia.
    The journal of obstetrics and gynaecology research, 1997, Volume: 23, Issue:3

    Topics: Adult; Anticonvulsants; Chlorpromazine; Diazepam; Eclampsia; Female; Humans; Magnesium Sulfate; Meperidine; Phenytoin; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Promethazine

1997
[Chlorpromazine potentiation of the anticonvulsant effect of diphenylhydantoin].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1954, Volume: 148, Issue:13-14

    Topics: Anticonvulsants; Chlorpromazine; Hydantoins; Phenytoin

1954
The influence of certain central depressants on fighting behavior of mice.
    Archives internationales de pharmacodynamie et de therapie, 1963, Mar-01, Volume: 142

    Topics: Animals; Behavior; Central Nervous System Agents; Chloral Hydrate; Chlorpromazine; Hypnotics and Sedatives; Meprobamate; Mice; Pentobarbital; Phenobarbital; Phenytoin; Reserpine

1963
THORAZINE AS AN EPILEPTOGENIC AGENT.
    The American journal of psychiatry, 1963, Volume: 120

    Topics: Chlorpromazine; Epilepsy; Humans; Pharmacology; Phenytoin; Primidone; Schizophrenia

1963
STIMULANT ACTION OF PYRIDYL DERIVATIVES OF BENZODIOXANS AND BENZODIOXEPANS.
    International journal of neuropharmacology, 1963, Volume: 2

    Topics: Animals; Anticonvulsants; Atropine; Bemegride; Central Nervous System Agents; Central Nervous System Stimulants; Chlorisondamine; Chlorpromazine; Diazepam; Mephenesin; Meprobamate; Mice; Pentylenetetrazole; Pharmacology; Phenobarbital; Phenytoin; Picrotoxin; Research; Seizures; Strychnine; Tranquilizing Agents

1963
CONVULSIVE EQUIVALENT SYNDROME OF CHILDHOOD.
    The Journal of pediatrics, 1964, Volume: 64

    Topics: Acetazolamide; Adolescent; Anticonvulsants; Autonomic Nervous System Diseases; Child; Chlorpromazine; Dextroamphetamine; Electroencephalography; Epilepsy; Humans; Infant; Meprobamate; Phenobarbital; Phenytoin; Statistics as Topic; Syndrome

1964
APLASTIC VERSUS HYPERPLASTIC BLOOD DYSCRASIAS.
    Postgraduate medicine, 1964, Volume: 35

    Topics: Anemia; Anemia, Aplastic; Anti-Bacterial Agents; Benzene; Bone Marrow Diseases; Chlorpromazine; Cobalt; DDT; Folic Acid Antagonists; Hematology; Humans; Iatrogenic Disease; Leukemia; Nitrogen Mustard Compounds; Nitrous Oxide; Phenylbutazone; Phenytoin; Promazine; Quinacrine; Sulfonamides; Thiouracil; Toxicology; Trinitrotoluene; Vitamins

1964
TWO CASES OF WITHDRAWAL FROM ETHCHLORVYNOL.
    The American journal of psychiatry, 1964, Volume: 120

    Topics: Chlorpromazine; Delirium; Epilepsy, Tonic-Clonic; Ethchlorvynol; Hallucinations; Hypnotics and Sedatives; Phenytoin; Schizophrenia; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders; Toxicology

1964
[INHIBITION OF ELECTROCONVULSION BY THE KAVA-PYRONES DIHYDROMETHYSTICIN AND DIHYDROKAVAIN].
    Archives internationales de pharmacodynamie et de therapie, 1964, Mar-01, Volume: 148

    Topics: Anticonvulsants; Chlorpromazine; Kava; Mice; Pharmacology; Phenobarbital; Phenytoin; Primidone; Pyrones; Rats; Research; Seizures

1964
EFFECTS OF BENZODIAZEPINES ON CENTRAL NERVOUS SYSTEM OF CAT.
    Archives internationales de pharmacodynamie et de therapie, 1964, Jun-01, Volume: 149

    Topics: Anticonvulsants; Benzodiazepines; Brain; Carbamates; Carisoprodol; Cats; Cerebral Cortex; Chlordiazepoxide; Chlorpromazine; Decerebrate State; Hypothalamus; Limbic System; Pentobarbital; Pharmacology; Phenobarbital; Phenytoin; Research; Thalamus; Tranquilizing Agents

1964
A NEUROPHARMACOLOGICAL STUDY OF GAMMA-AMINOBUTYRIC ACID (GABA).
    Archives internationales de pharmacodynamie et de therapie, 1964, Aug-01, Volume: 150

    Topics: Aminobutyrates; Anesthesia; Anesthesia, Intravenous; Behavior, Animal; Brain Chemistry; Cats; Chlorpromazine; Electroencephalography; Electroshock; gamma-Aminobutyric Acid; Hydroxylamines; Metabolism; Neuropharmacology; Pentobarbital; Pentylenetetrazole; Pharmacology; Phenytoin; Research; Reserpine; Seizures; Strychnine; Toxicology

1964
BENZQUINAMIDE IN THE TREATMENT OF PSYCHOTIC PATIENTS.
    Diseases of the nervous system, 1964, Volume: 25

    Topics: Chlorpromazine; Chlorprothixene; Drug Therapy; Humans; Mental Disorders; Phenytoin; Psychotic Disorders; Quinolizines; Thioridazine; Tranquilizing Agents; Trifluoperazine; Trimeprazine

1964
TOXIC EPIDERMAL NECROLYSIS.
    JAMA, 1965, Mar-22, Volume: 191

    Topics: Alcoholism; Anti-Bacterial Agents; Chloramphenicol; Chlorpromazine; Drug Eruptions; Drug Therapy; Humans; Hydrocortisone; Mannitol; Methicillin; Paraldehyde; Pathology; Phenytoin; Stevens-Johnson Syndrome; Tetracycline; Thiamine; Toxicology

1965
THE BROADER TREATMENT OF ACUTE ALCOHOLISM AND DELIRIUM TREMENS.
    The Journal of the Florida Medical Association. Florida Medical Association, 1965, Volume: 52

    Topics: Alcohol Withdrawal Delirium; Alcoholism; Chlorpromazine; Drug Therapy; Humans; Phenytoin; Psychoses, Alcoholic; Psychotic Disorders; Reserpine; Vitamin A; Vitamin K; Vitamins

1965
Preliminary findings from the National Register of Antipsychotic Medication in Pregnancy.
    The Australian and New Zealand journal of psychiatry, 2008, Volume: 42, Issue:1

    Topics: Adult; Antipsychotic Agents; Australia; Benzodiazepines; Chlorpromazine; Cross-Sectional Studies; Data Collection; Female; Humans; Infant, Newborn; Olanzapine; Phenytoin; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications; Psychotic Disorders; Registries; Risk Factors; Substance Withdrawal Syndrome; Suicide

2008
Interaction of injectable neurotropic drugs with the red cell membrane.
    Toxicology in vitro : an international journal published in association with BIBRA, 2014, Volume: 28, Issue:7

    Topics: Central Nervous System Agents; Chlorpromazine; Citalopram; Clomipramine; Clonazepam; Diazepam; Erythrocytes; Humans; Injections; Levetiracetam; Microscopy, Electron, Scanning; Neurotransmitter Agents; Phenobarbital; Phenytoin; Piracetam; Valproic Acid

2014