chlorpromazine and oxazepam

chlorpromazine has been researched along with oxazepam in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199018 (48.65)18.7374
1990's0 (0.00)18.2507
2000's11 (29.73)29.6817
2010's8 (21.62)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B1
Duffy, EM; Jorgensen, WL1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Caron, G; Ermondi, G1
Briand, X; Faller, B; Lázaro, E; Lowe, PJ1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Ganeshpurkar, A; Gupta, SK; Gutti, G; Krishnamurthy, S; Kumar, D; Modi, G; Singh, SK1
Rai, SN; Shankar, S; Sharma, P; Shrivastava, SK; Singh, SP; Srivastava, P; Srivastava, RK; Tripathi, PN1
Sharma, P; Shrivastava, SK; Srivastava, P; Tripathi, PN1
Bockisch, A; Terhaag, B1
Schenker, S1
Carter, CS; Daily, RF; Leaf, R1
Carney, MW1
Stewart, JT; Wilkin, RE1
Greenblatt, DJ; Shader, RI1
Akinlaja, A; Opitz, K1
Dlabac, A; Podvalová, I1
Danneberg, P; Knappen, F; Minck, K1
Boissier, JR; Schoonhoed, L; Simon, P; Soubrie, P; Wlodaver, C1
McMillan, DE1
Boissier, JR; Simon, P; Soubrié, P; Thiébot, MH1
Harcup, M; Jain, VK; Magowan, S; Tewfik, GI1
Malick, JB1
Bauen, A; Possanza, GJ1
Katz, MH; Krop, S; Yen, HC1
Lamon, S; Leaf, RC; Wnek, DJ1
Davis, JM; Dysken, MW; Hicks, R; Lazarus, L; Lesser, J; Ripeckyj, A1

Reviews

4 review(s) available for chlorpromazine and oxazepam

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
The clinical choice of sedative-hypnotics.
    Annals of internal medicine, 1972, Volume: 77, Issue:1

    Topics: Animals; Anticoagulants; Barbiturates; Chloral Hydrate; Chlordiazepoxide; Chlorpromazine; Diazepam; Drug Interactions; Enzyme Induction; Ethchlorvynol; Glutethimide; Guinea Pigs; Humans; Hypnotics and Sedatives; Meprobamate; Methaqualone; Oxazepam; Phenindione; Rats; Sleep, REM; Tranquilizing Agents

1972
The pharmacokinetics of psychotropic medication in the elderly: a review.
    The Journal of clinical psychiatry, 1981, Volume: 42, Issue:10

    Topics: Aged; Alcoholism; Analgesics; Antidepressive Agents, Tricyclic; Barbiturates; Biological Availability; Biotransformation; Chlorpromazine; Drug Interactions; Flurazepam; Humans; Intestinal Absorption; Kidney; Kinetics; Lithium; Monoamine Oxidase Inhibitors; Nitrazepam; Oxazepam; Parasympatholytics; Physostigmine; Propranolol; Psychotropic Drugs; Tobacco Use Disorder

1981

Trials

1 trial(s) available for chlorpromazine and oxazepam

ArticleYear
Effectiveness of various tranquilisers in the management of senile restlessness.
    Gerontologia clinica, 1970, Volume: 12, Issue:6

    Topics: Aged; Carbamates; Chlorpromazine; Clinical Trials as Topic; Dementia; Female; Haloperidol; Humans; Hyperkinesis; Male; Middle Aged; Oxazepam; Placebos; Thioridazine; Tranquilizing Agents

1970

Other Studies

32 other study(ies) available for chlorpromazine and oxazepam

ArticleYear
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
    Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11

    Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
New approach to measure protein binding based on a parallel artificial membrane assay and human serum albumin.
    Journal of medicinal chemistry, 2008, Apr-10, Volume: 51, Issue:7

    Topics: Humans; Kinetics; Membranes, Artificial; Permeability; Protein Binding; Serum Albumin

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Development of Piperazinediones as dual inhibitor for treatment of Alzheimer's disease.
    European journal of medicinal chemistry, 2018, Apr-25, Volume: 150

    Topics: Acetylcholinesterase; Alzheimer Disease; Butyrylcholinesterase; Diketopiperazines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Matrix Metalloproteinase 2; Molecular Structure; Neuroprotective Agents; Structure-Activity Relationship

2018
Design and development of some phenyl benzoxazole derivatives as a potent acetylcholinesterase inhibitor with antioxidant property to enhance learning and memory.
    European journal of medicinal chemistry, 2019, Feb-01, Volume: 163

    Topics: Antioxidants; Benzoxazoles; Cholinesterase Inhibitors; Drug Design; Humans; Learning; Memory; Pharmacokinetics; Quantitative Structure-Activity Relationship

2019
Design, synthesis, and evaluation of novel N-(4-phenoxybenzyl)aniline derivatives targeting acetylcholinesterase, β-amyloid aggregation and oxidative stress to treat Alzheimer's disease.
    Bioorganic & medicinal chemistry, 2019, 08-15, Volume: 27, Issue:16

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Drug Design; Humans; Oxidative Stress

2019
[Antihemolytic effect of various benzodiazepines on human erythrocytes].
    Acta biologica et medica Germanica, 1976, Volume: 35, Issue:10

    Topics: Anti-Anxiety Agents; Chlordiazepoxide; Chlorpromazine; Erythrocytes; Hemolysis; Humans; Medazepam; Oxazepam

1976
Effects of liver disease and of aging on the disposition and elimination of sedatives.
    Transactions of the American Clinical and Climatological Association, 1978, Volume: 89

    Topics: Aging; Anti-Anxiety Agents; Chlordiazepoxide; Chlorpromazine; Diazepam; Half-Life; Hepatitis, Viral, Human; Humans; Liver Cirrhosis; Liver Diseases; Lorazepam; Meprobamate; Oxazepam

1978
Effects of chlordiazepoxide, oxazepam, chlorpromazine, and d-amphetamine on sexual responses in male and female hamsters.
    Psychopharmacology, 1977, Dec-19, Volume: 55, Issue:2

    Topics: Animals; Chlordiazepoxide; Chlorpromazine; Cricetinae; Depression, Chemical; Dextroamphetamine; Dose-Response Relationship, Drug; Female; Injections, Intraperitoneal; Male; Oxazepam; Sexual Behavior, Animal

1977
Hepatic porphyria with mental symptoms. Four missed cases.
    Lancet (London, England), 1972, Jul-15, Volume: 2, Issue:7768

    Topics: Adult; Chlorpromazine; Diagnostic Errors; Female; Follow-Up Studies; Humans; Liver Diseases; Male; Mental Disorders; Middle Aged; Oxazepam; Paraldehyde; Porphyrias; Prognosis; Promazine; Reserpine

1972
Determination of sulfonamides and local anesthetics with 9=chloroacridine by quenching fluorometry.
    Journal of pharmaceutical sciences, 1972, Volume: 61, Issue:3

    Topics: 4-Aminobenzoic Acid; Acridines; Aminobenzoates; Anesthetics, Local; Aspirin; Benzocaine; Chlorine; Chlorpromazine; Ephedrine; Fluorescence; Methods; Oxazepam; Phenobarbital; Spectrometry, Fluorescence; Sulfamethizole; Sulfamethoxypyridazine; Sulfanilamides; Sulfathiazoles; Sulfisoxazole; Sulfonamides; Tetracycline

1972
[On the influencing of food intake by psychotropic drugs].
    Psychopharmacologia, 1966, Volume: 9, Issue:4

    Topics: Amitriptyline; Animals; Behavior, Animal; Body Weight; Central Nervous System; Central Nervous System Stimulants; Chlordiazepoxide; Chlorpromazine; Chlorprothixene; Eating; Feeding and Eating Disorders; Female; Haloperidol; Humans; Imipramine; Nutritional Physiological Phenomena; Oxazepam; Oxazoles; Pemoline; Phenobarbital; Piperidines; Promethazine; Psychopharmacology; Rats; Reserpine; Thiazines

1966
Aggressive behavior of rats induced by mesorgydine (Lysenyl Spofa).
    Activitas nervosa superior, 1970, Jan-12, Volume: 12, Issue:1

    Topics: Aggression; Animals; Chlordiazepoxide; Chlorpromazine; Dibenzothiepins; Drug Antagonism; Histamine H1 Antagonists; Humans; Oxazepam; Rats; Serotonin Antagonists

1970
[Effects of psychotropic drugs on exploratory behavior of mice (author's transl)].
    Psychopharmacologia, 1974, Volume: 39, Issue:3

    Topics: Amphetamine; Animals; Behavior, Animal; Chlordiazepoxide; Chlorpromazine; Diazepam; Dose-Response Relationship, Drug; Exploratory Behavior; Female; Haloperidol; Imipramine; Locomotion; Mescaline; Mice; Motor Activity; Oxazepam; Phenobarbital; Psychotropic Drugs; Reserpine; Statistics as Topic

1974
Preselection of animals in studies of anti-anxiety drugs.
    Neuropharmacology, 1974, Volume: 13, Issue:8

    Topics: Analysis of Variance; Animals; Behavior, Animal; Chlorpromazine; Dextroamphetamine; Diazepam; Emotions; Hot Temperature; Imipramine; Male; Oxazepam; Rats; Stomach Ulcer; Tranquilizing Agents

1974
Drugs and punished responding. I. Rate-dependent effects under multiple schedules.
    Journal of the experimental analysis of behavior, 1973, Volume: 19, Issue:1

    Topics: Animals; Chlordiazepoxide; Chlorpromazine; Columbidae; Conditioning, Operant; Dextroamphetamine; Diazepam; Dronabinol; Feeding Behavior; Imipramine; Male; Meprobamate; Mescaline; Morphine; Oxazepam; Pentobarbital; Psychopharmacology; Punishment; Reinforcement Schedule; Tetrabenazine

1973
[Dissociation of two components of rat behaviour by psychotropic drugs. Utilization for studying anxiolytic drugs].
    Psychopharmacologia, 1973, Jul-04, Volume: 31, Issue:1

    Topics: Amobarbital; Animals; Benzoxazoles; Chlormezanone; Chlorpromazine; Dextroamphetamine; Diazepam; Ethanol; Exploratory Behavior; Haloperidol; Locomotion; Male; Mephenesin; Meprobamate; Oxazepam; Prazepam; Rats; Tranquilizing Agents

1973
Effects of selected drugs on stimulus-bound emotional behavior elicited by hypothalamic stimulation in the cat.
    Archives internationales de pharmacodynamie et de therapie, 1970, Volume: 186, Issue:1

    Topics: Animals; Behavior, Animal; Benzazepines; Cats; Chlordiazepoxide; Chlorpromazine; Diazepam; Electric Stimulation; Emotions; Hypothalamus; Imipramine; Oxazepam; Phenobarbital; Tranquilizing Agents; Tranylcypromine

1970
The mink as a psychopharmacological model.
    Archives internationales de pharmacodynamie et de therapie, 1970, Volume: 186, Issue:1

    Topics: Aggression; Animals; Chlordiazepoxide; Chlorpromazine; Diazepam; Humans; Male; Meprobamate; Mink; Models, Biological; Oxazepam; Pentobarbital; Tranquilizing Agents

1970
Effects of various drugs on 3,4-dihydroxyphenylalanine (DL-DOPA)-induced excitation (agressive behavior) in mice.
    Toxicology and applied pharmacology, 1970, Volume: 17, Issue:3

    Topics: Aggression; Animals; Antidepressive Agents; Autonomic Agents; Behavior, Animal; Bretylium Compounds; Chlordiazepoxide; Chlorpromazine; Diazepam; Dihydroxyphenylalanine; Drug Antagonism; Haloperidol; Hexobarbital; Humans; Imipramine; Iproniazid; Male; Mice; Morphine; Oxazepam; Reserpine; Tranquilizing Agents; Tranylcypromine; Trifluoperazine

1970
Oxazepam induced mouse killing by rats.
    Pharmacology, biochemistry, and behavior, 1984, Volume: 20, Issue:2

    Topics: Aggression; Animals; Chlordiazepoxide; Chlorpromazine; Dose-Response Relationship, Drug; Humans; Male; Meprobamate; Mice; Oxazepam; Pilocarpine; Rats; Time Factors

1984