Compounds > chlorpromazine

chlorpromazine and olanzapine

chlorpromazine has been researched along with olanzapine in 103 studies

Research

Studies (103)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (5.83)18.2507
2000's61 (59.22)29.6817
2010's32 (31.07)24.3611
2020's4 (3.88)2.80

Authors

AuthorsStudies
Choudhary, MS; Craigo, SC; Meltzer, HY; Monsma, FJ; Roth, BL; Shen, Y; Sibley, DR; Uluer, A1
Druck, T; Hamblin, MW; Huebner, K; Khan, N; Kohen, R; Lachowicz, JE; Meltzer, HY; Metcalf, MA; Roth, BL; Sibley, DR1
Audinot, V; Chaput, C; Conte, C; Gavaudan, S; Millan, MJ; Newman-Tancredi, A; Touzard, M; Verrièle, L1
Topliss, JG; Yoshida, F1
Grinde, E; Herrick-Davis, K; Teitler, M1
Boulton, DW; DeVane, CL; Liston, HL; Markowitz, JS1
Ernsberger, P; Hufeisen, SJ; Jayathilake, K; Kroeze, WK; Meltzer, HY; Popadak, BA; Renock, SM; Roth, BL; Steinberg, S1
Keserü, GM1
Andaluz, B; Buschmann, H; Codony, X; Cubí, R; Díaz, JL; Dordal, A; Guitart, X; Hernández, E; Hernández, S; Holenz, J; Mas, J; Mercè, R; Monroy, X; Pérez, R; Romero, G; Sánchez, E; Sanfeliu, O; Torrens, A1
Herrick-Davis, K; Purohit, A; Smith, C; Teitler, M1
Nagashima, R; Nishikawa, T; Tobita, M1
Abraham, MH; Acree, WE; Ibrahim, A1
Coolen, HK; Glennon, JC; Kruse, CG; Lange, JH; Reinders, JH; Tolboom, JT1
Farasati, NA; Huang, Y; Randhawa, P1
Jia, L; Sun, H1
Ahman, M; Holmén, AG; Wan, H1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Sen, S; Sinha, N1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Bienkowski, P; Bucki, A; Jaśkowska, J; Kazek, G; Kowalski, P; Kołaczkowski, M; Marcinkowska, M; Mierzejewski, P; Mitka, K; Pawłowski, M; Siwek, A; Wasik, A; Wesołowska, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bączek, T; Belka, M; Bojarski, A; Herold, F; Kleps, J; Kozioł, AE; Król, M; Nowak, G; Siwek, A; Ślifirski, G; Stachowicz, K; Szewczyk, B; Turło, J; Ulenberg, S1
Bączek, T; Belka, M; Bojarski, A; Herold, F; Kleps, J; Kozioł, AE; Król, M; Nowak, G; Podsadni, P; Siwek, A; Ślifirski, G; Stachowicz, K; Szewczyk, B; Turło, J1
Meyer, JM; Simpson, GM1
Bartko, JJ; Conley, RR; Gounaris, C; Hegerty, J; Lingle, J; Love, R; Peszke, M; Richardson, C; Tamminga, CA; Zaremba, S1
De Bittencourt, PR; Hanel, RA; Kranich, M; Sandmann, MC1
Farver, D; Khan, M1
McCallum, SE; Porter, JH; Vann, RE; Varvel, SA1
Kameda, K; Koyama, T; Kusumi, I; Suzuki, K; Takahashi, Y1
Mueser, KT; Noordsy, DL; O'Keefe, C; Xie, H1
Copolov, DL; Dean, B; Hussain, T; Pavey, G; Scarr, E1
Nomikos, GG; Rodriguez, DE; Shirazi-Southall, S1
Dean, B; Parkin, FM; Pavey, G; Scarr, E1
Hägg, S; Hedenmalm, K; Mortimer, O; Spigset, O; Ståhl, M1
Kalkman, HO; Loetscher, E1
Woods, SW1
Koponen, H; Larmo, I1
Andersen, J; Duncan, E; Dunlop, BW; Phillips, LS; Sternberg, M1
Bowers, L; Callaghan, P; Clark, N; Evers, C1
Burnet, PW; Harrison, PJ; Hutchinson, LJ; Law, AJ1
Arndt, S; Conley, RR; McMahon, RP1
Lawrie, S; McIntosh, A; Nadeem, Z1
Appelberg, B; Joffe, G; Tuisku, K1
Beumont, P; Birmingham, CL; Chapman, L; Mondraty, N; Sundakov, V; Touyz, S1
Lawrie, S; McIntosh, A1
Koga, M; Nakayama, K1
Adams, AS; Kanavos, P; Park, S; Ross-Degnan, D; Sabin, J; Soumerai, SB1
Dwyer, DS; Lu, XH1
Geddes, J1
Balit, CR; Isbister, GK; Kilham, HA1
Mahadik, SP; Pillai, A; Terry, AV1
Bareggi, S; Bonomi, A; Cavicchini, L; Croera, C; Guizzardi, F; Pessina, A; Turlizzi, E1
Mahadik, SP; Parikh, V; Pillai, A; Terry, AV1
Awad, AG1
Bianchi, MG; Bussolati, O; Dall'Asta, V; Gazzola, GC; Maggini, C; Marchesi, C; Rotoli, BM1
Iwata, S; Miyata, A; Morioka, H1
DeVane, CL; Donovan, JL; Markowitz, JS; Wang, JS; Zhu, HJ1
Goghari, VM; Honer, WG; Khorram, B; Kopala, LC; Lang, DJ; Rui, Q; Smith, GN; Vandorpe, RA1
Boshoven, W; Duncan, E; Dunlop, BW; Hamer, RM; Phillips, LS; Woolson, SL1
Dierks, T; Irisawa, S; Isotani, T; Kikuchi, M; Kinoshita, T; Koenig, T; Okugawa, G; Strik, W; Yagyu, T; Yamada, K; Yoshimura, M1
Dominguez, S; Dossenbach, M; Huang, X; Kryzhanovskaya, L; Saylan, M; Treuer, T1
Brodaty, H; Cumming, R; Forrester, L; Grayson, D; Hollis, J; Touyz, S2
Arranz, MJ; Correa, JC; de Leon, J; Diaz, FJ; Ruaño, G; Windemuth, A1
de Castella, A; Fitzgerald, P; Gilbert, H; Gurvich, C; Kulkarni, J; Marston, N; McCauley-Elsom, K1
Agius, M; Campbell, M; Ramkisson, R1
Coffey, BJ; Kimmel, S; Rais, AR; Rais, TB; Shrestha, N1
Athey, R; Forlano, R; Singh, D1
Bartlett, MG; Mahadik, SP; Pillai, A; Terry, AV; Vandenhuerk, L; Warner, SE; Zhang, G1
Graudins, A; Green, D; Morris, E1
Gillman, K1
Buyukoglan, H; Kaya, MG; Ulusoy, HB; Yagmur, F1
Bustad, HJ; Gjerde, AU; Holmsen, H; Ngo, TH; Simeunović, A; Steinkopf, S; Sveaass, H1
Siman, E; Stewart, SL; Swart, GT1
Aw, CC; Browne, ER; Hirano, K; Nasir, S; Rutter, AR; Searle, KL1
Lam, D; Patten, SB; Pringsheim, T; Tano, DS1
Umeda, K1
Miller, CL1
Berk, M; Conus, P; Cotton, SM; Daglas, R; Gentle, E; Hasty, MK; Henry, L; Macneil, CA; McGorry, PD; Shelton, CL; Smith, LT1
Berk, M; Conus, P; Cotton, SM; Daglas, R; Hallam, KT; Hasty, MK; Kader, L; Macneil, CA1
Choi, NK; Lee, J; Lee, SH; Park, BJ; Park, MJ; Seong, JM; Shin, JY1
Pałasz, A; Rojczyk, E; Wiaderkiewicz, R2
Babigumira, JB; Lubinga, SJ; Mutamba, BB; Nganizi, A1
Andrews, JL; Engel, M; Fernandez-Enright, F; Huang, XF; Lum, JS; Matosin, N; Newell, KA1
Pałasz, A; Rojczyk, E1
Berk, M; Conus, P; Cotton, SM; Hallam, K; Hasty, MK; Kader, L; Lambert, M; Macneil, C; McGorry, PD; Murphy, BP1
Flanagan, RJ; Handley, S; Patel, MX1
Bo, L; Saha, KB; Sampson, S; Xia, J; Zaman, RU; Zhao, S1
Choy, BNK; Fan, MCY; Lai, JSM; Ng, ALK; Shum, JWH1
Adams, E; Broeckhoven, K; Cabooter, D; Hendrickx, S; Şener, E; Uğur, DY; Van Schepdael, A; Yilmaz, IT1
Arasappa, R; Chand, PK; Kulkarni, K; Muralidharan, K; Murthy, P; Philip, M; Prasad M, K; Zutshi, A1
Beloti, LGM; Miranda, LFC; Queiroz, MEC1
Basu, B; John Jayakumar, JAK; Panicker, MM1
Abe, Y; Hamamatsu, S; Hattori, Y; Ikegami, Y; Iwata, N; Matsuo, K; Matsuoka, Y; Obara, K; Shioda, N; Tanaka, Y; Yamaki, F; Yoshio, T; Yoshioka, K1
Osman, E; Yıldız, M1
Hashimoto, N; Ishikawa, S; Ito, YM; Kusumi, I; Miyakoshi, T; Okubo, R; Sato, N1

Reviews

10 review(s) available for chlorpromazine and olanzapine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Rapid resolution of antipsychotic-induced tardive dyskinesia with olanzapine.
    South Dakota journal of medicine, 2000, Volume: 53, Issue:2

    Topics: Aged; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Chlorpromazine; Chronic Disease; Dyskinesia, Drug-Induced; Humans; Male; Olanzapine; Pirenzepine; Selective Serotonin Reuptake Inhibitors

2000
Chlorpromazine equivalent doses for the newer atypical antipsychotics.
    The Journal of clinical psychiatry, 2003, Volume: 64, Issue:6

    Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Chlorpromazine; Dibenzothiazepines; Dose-Response Relationship, Drug; Drug Administration Schedule; Haloperidol; Humans; Olanzapine; Piperazines; Pirenzepine; Quetiapine Fumarate; Quinolones; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia; Therapeutic Equivalency; Thiazoles

2003
Schizophrenia.
    Clinical evidence, 2003, Issue:10

    Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clozapine; Cognitive Behavioral Therapy; Dibenzothiepins; Haloperidol; Humans; Olanzapine; Patient Compliance; Perazine; Pimozide; Risperidone; Schizophrenia; Sulpiride

2003
Schizophrenia.
    Clinical evidence, 2004, Issue:12

    Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clozapine; Haloperidol; Humans; Olanzapine; Patient Compliance; Perazine; Pimozide; Risperidone; Schizophrenia; Sulpiride

2004
Bipolar disorder.
    Clinical evidence, 2005, Issue:13

    Topics: Antidepressive Agents; Antimanic Agents; Benzodiazepines; Bipolar Disorder; Chlorpromazine; Cognitive Behavioral Therapy; Humans; Lithium Carbonate; Olanzapine; Piperazines; Thiazoles; Valproic Acid

2005
Antipsychotic poisoning in young children: a systematic review.
    Drug safety, 2005, Volume: 28, Issue:11

    Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Child; Child, Preschool; Chlorpromazine; Clozapine; Dibenzothiazepines; Haloperidol; Humans; Infant; Infant, Newborn; Olanzapine; Pimozide; Piperazines; Poisoning; Quetiapine Fumarate; Quinolones; Risperidone

2005
[Antipsychotics].
    Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology, 2011, Volume: 24, Issue:4

    Topics: Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clozapine; Drug Discovery; Drug Interactions; Haloperidol; History, 20th Century; History, 21st Century; Humans; Olanzapine

2011
Antipsychotic-related fatal poisoning, England and Wales, 1993-2013: impact of the withdrawal of thioridazine.
    Clinical toxicology (Philadelphia, Pa.), 2016, Volume: 54, Issue:6

    Topics: Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clozapine; Drug Recalls; England; Heroin; Humans; Methadone; Morphine; Olanzapine; Poisoning; Quetiapine Fumarate; Thioridazine; Wales

2016
Chlorpromazine versus atypical antipsychotic drugs for schizophrenia.
    The Cochrane database of systematic reviews, 2016, Apr-05, Volume: 4

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Humans; Olanzapine; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia

2016

Trials

9 trial(s) available for chlorpromazine and olanzapine

ArticleYear
Olanzapine compared with chlorpromazine in treatment-resistant schizophrenia.
    The American journal of psychiatry, 1998, Volume: 155, Issue:7

    Topics: Adult; Akathisia, Drug-Induced; Analysis of Variance; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Brief Psychiatric Rating Scale; Chlorpromazine; Double-Blind Method; Drug Administration Schedule; Female; Haloperidol; Headache; Humans; Male; Olanzapine; Pirenzepine; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Sleep Stages; Treatment Outcome; Xerostomia

1998
Six-month outcomes for patients who switched to olanzapine treatment.
    Psychiatric services (Washington, D.C.), 2001, Volume: 52, Issue:4

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Brief Psychiatric Rating Scale; Chlorpromazine; Dose-Response Relationship, Drug; Female; Humans; Male; Mental Disorders; Middle Aged; Olanzapine; Pirenzepine; Prospective Studies; Severity of Illness Index; Time Factors; Treatment Outcome

2001
Is it worth while changing clinically stable schizophrenic out-patients with mild to moderate residual symptoms and/or side effects from conventional to atypical antipsychotics? A prospective, randomised study with olanzapine.
    European psychiatry : the journal of the Association of European Psychiatrists, 2004, Volume: 19, Issue:8

    Topics: Adult; Ambulatory Care; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Female; Humans; Male; Middle Aged; Olanzapine; Prospective Studies; Schizophrenia

2004
Randomized controlled trial of olanzapine in the treatment of cognitions in anorexia nervosa.
    Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists, 2005, Volume: 13, Issue:1

    Topics: Adult; Anorexia Nervosa; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Cognition Disorders; Drug Administration Schedule; Female; Humans; Male; Olanzapine

2005
A pharmaco-EEG study on antipsychotic drugs in healthy volunteers.
    Psychopharmacology, 2007, Volume: 191, Issue:4

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Cross-Over Studies; Dibenzothiazepines; Electroencephalography; Fourier Analysis; Haloperidol; Humans; Indoles; Isoindoles; Male; Olanzapine; Quetiapine Fumarate; Reference Values; Risperidone; Single-Blind Method; Thiazoles; Time Factors

2007
Olanzapine versus chlorpromazine in the treatment of schizophrenia: a pooled analysis of four 6-week, randomized, open-label studies in the Middle East and North Africa.
    Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:4

    Topics: Adolescent; Adult; Africa, Northern; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Dyskinesia, Drug-Induced; Electrocardiography; Endpoint Determination; Female; Humans; Male; Middle Aged; Middle East; Olanzapine; Psychiatric Status Rating Scales; Schizophrenia

2007
The impact of insight in a first-episode mania with psychosis population on outcome at 18 months.
    Journal of affective disorders, 2014, Volume: 167

    Topics: Adult; Antipsychotic Agents; Awareness; Benzodiazepines; Bipolar Disorder; Chi-Square Distribution; Chlorpromazine; Depression; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Judgment; Linear Models; Lithium Compounds; Male; Middle Aged; Olanzapine; Predictive Value of Tests; Prognosis; Psychotic Disorders; Severity of Illness Index; Social Adjustment

2014
The impact of past direct-personal traumatic events on 12-month outcome in first episode psychotic mania: trauma and early psychotic mania.
    The Australian and New Zealand journal of psychiatry, 2014, Volume: 48, Issue:11

    Topics: Adolescent; Adult; Analysis of Variance; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Chlorpromazine; Employment; Female; Follow-Up Studies; Humans; Male; Olanzapine; Patient Outcome Assessment; Prospective Studies; Psychiatric Status Rating Scales; Retrospective Studies; Social Behavior; Stress, Psychological; Surveys and Questionnaires; Treatment Outcome; Violence; Young Adult

2014
Olanzapine or chlorpromazine plus lithium in first episode psychotic mania: An 8-week randomised controlled trial.
    European psychiatry : the journal of the Association of European Psychiatrists, 2015, Volume: 30, Issue:8

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Chlorpromazine; Diagnostic and Statistical Manual of Mental Disorders; Drug Monitoring; Female; Humans; Lithium; Male; Olanzapine; Psychotic Disorders; Treatment Outcome

2015

Other Studies

84 other study(ies) available for chlorpromazine and olanzapine

ArticleYear
Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:3

    Topics: Animals; Antipsychotic Agents; Cell Line; Molecular Structure; Rats; Receptors, Serotonin

1994
Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor.
    Journal of neurochemistry, 1996, Volume: 66, Issue:1

    Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Antipsychotic Agents; Base Sequence; Brain Chemistry; Cell Line, Transformed; Chlorocebus aethiops; Chromosome Mapping; Chromosomes, Human, Pair 1; Cloning, Molecular; Clozapine; DNA, Complementary; Genes; Humans; Kinetics; Molecular Sequence Data; Open Reading Frames; Protein Conformation; Rats; Receptors, Serotonin; Recombinant Proteins; Sequence Alignment; Sequence Homology, Nucleic Acid; Serotonin Agents; Signal Transduction; Species Specificity

1996
Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35S]GTPgammaS binding study.
    European journal of pharmacology, 1998, Aug-21, Volume: 355, Issue:2-3

    Topics: Animals; Antipsychotic Agents; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Sulfur Radioisotopes

1998
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Inverse agonist activity of atypical antipsychotic drugs at human 5-hydroxytryptamine2C receptors.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 295, Issue:1

    Topics: Animals; Antipsychotic Agents; COS Cells; Dose-Response Relationship, Drug; Humans; Inositol Phosphates; Radioligand Assay; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Receptor Agonists

2000
In vitro P-glycoprotein affinity for atypical and conventional antipsychotics.
    Life sciences, 2002, May-31, Volume: 71, Issue:2

    Topics: Antipsychotic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzodiazepines; Binding, Competitive; Clozapine; Dibenzothiazepines; Dose-Response Relationship, Drug; Humans; Kinetics; Olanzapine; Pirenzepine; Quetiapine Fumarate; Recombinant Proteins; Risperidone

2002
H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:3

    Topics: Animals; Antipsychotic Agents; Discriminant Analysis; Drug Evaluation, Preclinical; Forecasting; Humans; Protein Binding; Receptors, Histamine H1; Statistics, Nonparametric; Weight Gain

2003
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2003
Medicinal chemistry driven approaches toward novel and selective serotonin 5-HT6 receptor ligands.
    Journal of medicinal chemistry, 2005, Mar-24, Volume: 48, Issue:6

    Topics: Adenylyl Cyclases; Benzoxazines; Cell Line; Humans; Indoles; Ligands; Piperidines; Radioligand Assay; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Sulfonamides

2005
Stable expression of constitutively activated mutant h5HT6 and h5HT7 serotonin receptors: inverse agonist activity of antipsychotic drugs.
    Psychopharmacology, 2005, Volume: 179, Issue:2

    Topics: Amino Acid Substitution; Antipsychotic Agents; Cell Line; Cyclic AMP; Humans; Mutagenesis, Site-Directed; Mutation; Radioligand Assay; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection

2005
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:3

    Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization

2008
Principal component analysis differentiates the receptor binding profiles of three antipsychotic drug candidates from current antipsychotic drugs.
    Journal of medicinal chemistry, 2007, Oct-18, Volume: 50, Issue:21

    Topics: Antipsychotic Agents; Basal Ganglia Diseases; Benzoxazines; Biogenic Monoamines; Humans; Hyperprolactinemia; Indoles; Metabolic Diseases; Phthalimides; Piperazines; Principal Component Analysis; Pyridines; Radioligand Assay; Receptors, Biogenic Amine; Weight Gain

2007
BK Virus replication in vitro: limited effect of drugs interfering with viral uptake and intracellular transport.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12

    Topics: Antiviral Agents; BK Virus; Cell Line; Chloroquine; Humans; Microbial Sensitivity Tests; Molecular Structure; Nystatin; Virus Replication

2007
Support vector machines classification of hERG liabilities based on atom types.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Novel arylsulfonamide derivatives with 5-HT₆/5-HT₇ receptor antagonism targeting behavioral and psychological symptoms of dementia.
    Journal of medicinal chemistry, 2014, Jun-12, Volume: 57, Issue:11

    Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Avoidance Learning; Benzoxazoles; Catalepsy; CHO Cells; Cricetulus; Dementia; Dopamine D2 Receptor Antagonists; HEK293 Cells; Humans; Male; Models, Molecular; Motor Activity; Radioligand Assay; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Sulfonamides

2014
Synthesis of novel pyrido[1,2-c]pyrimidine derivatives with rigidized tryptamine moiety as potential SSRI and 5-HT
    European journal of medicinal chemistry, 2019, Mar-15, Volume: 166

    Topics: Animals; Chemistry Techniques, Synthetic; Drug Design; Ligands; Mice; Pyrimidines; Receptor, Serotonin, 5-HT1A; Selective Serotonin Reuptake Inhibitors; Structure-Activity Relationship; Tryptamines

2019
Synthesis of new 5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine derivatives with rigidized tryptamine moiety as potential SSRI and 5-HT
    European journal of medicinal chemistry, 2019, Oct-15, Volume: 180

    Topics: Animals; Cells, Cultured; Crystallography, X-Ray; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Ligands; Male; Mice; Models, Molecular; Molecular Structure; Pyrimidines; Rats; Receptor, Serotonin, 5-HT1A; RNA-Binding Proteins; Structure-Activity Relationship; Tryptamines

2019
From chlorpromazine to olanzapine: a brief history of antipsychotics.
    Psychiatric services (Washington, D.C.), 1997, Volume: 48, Issue:9

    Topics: Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clozapine; History, 20th Century; Humans; Olanzapine; Pirenzepine; Psychotic Disorders

1997
[Neuroleptic malignant syndrome: case report with recurrence associated with the use of olanzapine].
    Arquivos de neuro-psiquiatria, 1998, Volume: 56, Issue:4

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Haloperidol; Humans; Male; Neuroleptic Malignant Syndrome; Olanzapine; Pirenzepine; Recurrence

1998
Olanzapine. Keep an eye on this neuroleptic.
    Canadian family physician Medecin de famille canadien, 2000, Volume: 46

    Topics: Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clinical Trials as Topic; Dopamine Antagonists; Double-Blind Method; Haloperidol; Humans; Olanzapine; Pirenzepine; Risperidone; Schizophrenia; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists

2000
The discriminative stimulus properties of the atypical antipsychotic olanzapine in rats.
    Psychopharmacology, 2000, Volume: 148, Issue:3

    Topics: Animals; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clozapine; Discrimination Learning; Generalization, Psychological; Haloperidol; Male; Olanzapine; Pirenzepine; Raclopride; Rats; Rats, Sprague-Dawley; Risperidone; Ritanserin; Scopolamine

2000
Differential effects of subchronic treatments with atypical antipsychotic drugs on dopamine D2 and serotonin 5-HT2A receptors in the rat brain.
    Journal of neural transmission (Vienna, Austria : 1996), 2000, Volume: 107, Issue:3

    Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain Chemistry; Chlorpromazine; Dopamine Antagonists; Dose-Response Relationship, Drug; Humans; Indoles; Isoindoles; Male; Olanzapine; Pirenzepine; Protein Binding; Quinolines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Selective Serotonin Reuptake Inhibitors; Thiazoles

2000
Atypical antipsychotic drugs: how much better are they?
    The Harvard mental health letter, 2001, Volume: 17, Issue:10

    Topics: Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clozapine; Haloperidol; Humans; Olanzapine; Pirenzepine

2001
Extended treatment with typical and atypical antipsychotic drugs differential effects on the densities of dopamine D2-like and GABAA receptors in rat striatum.
    Life sciences, 2001, Aug-03, Volume: 69, Issue:11

    Topics: Animals; Antipsychotic Agents; Benzamides; Benzazepines; Benzodiazepines; Chlorpromazine; Clozapine; Corpus Striatum; Dose-Response Relationship, Drug; Haloperidol; Male; Muscimol; Olanzapine; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, GABA-A

2001
Effects of typical and atypical antipsychotics and receptor selective compounds on acetylcholine efflux in the hippocampus of the rat.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2002, Volume: 26, Issue:5

    Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clozapine; Dialysis Solutions; Dopamine Antagonists; Extracellular Space; Haloperidol; Hippocampus; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Microdialysis; Olanzapine; Piperazines; Pirenzepine; Rats; Rats, Wistar; Risperidone; Serotonin Antagonists; Thiazoles; Thioridazine

2002
Decreased density of [3H]TCP binding following antipsychotic drug withdrawal in rats.
    Life sciences, 2002, Apr-19, Volume: 70, Issue:22

    Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain; Chlorpromazine; Clozapine; Haloperidol; Ion Channels; Male; Olanzapine; Phencyclidine; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome

2002
Glucose intolerance with atypical antipsychotics.
    Drug safety, 2002, Volume: 25, Issue:15

    Topics: Adverse Drug Reaction Reporting Systems; Antipsychotic Agents; Bayes Theorem; Benzodiazepines; Chlorpromazine; Clozapine; Diabetes Mellitus; Glucose Intolerance; Haloperidol; Humans; Hyperglycemia; Olanzapine; Pirenzepine; Risk Factors; Risperidone; World Health Organization

2002
alpha2C-Adrenoceptor blockade by clozapine and other antipsychotic drugs.
    European journal of pharmacology, 2003, Feb-21, Volume: 462, Issue:1-3

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Brimonidine Tartrate; Chlorpromazine; CHO Cells; Clozapine; Cricetinae; Cyclic AMP; Dibenzothiazepines; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Gene Expression; Haloperidol; Humans; Isoxazoles; Norepinephrine; Olanzapine; Piperazines; Piperidines; Pirenzepine; Quetiapine Fumarate; Quinolones; Quinoxalines; Receptors, Adrenergic, alpha-2; Receptors, Dopamine D2; Risperidone; Thiazoles; Transfection; Yohimbine

2003
Reversal of antipsychotic-induced weight gain during quetiapine treatment.
    International clinical psychopharmacology, 2003, Volume: 18, Issue:6

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Brain Injuries; Chlorpromazine; Dibenzothiazepines; Humans; Male; Obesity; Olanzapine; Quetiapine Fumarate; Schizophrenia, Paranoid; Weight Gain; Weight Loss

2003
Disturbed glucose metabolism among patients taking olanzapine and typical antipsychotics.
    Psychopharmacology bulletin, 2003,Summer, Volume: 37, Issue:3

    Topics: Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Cohort Studies; Depressive Disorder; Diabetes Mellitus; Female; Fluphenazine; Glucose; Haloperidol; Humans; Male; Middle Aged; Olanzapine; Perphenazine; Retrospective Studies

2003
Comparisons of psychotropic drug prescribing patterns in acute psychiatric wards across Europe.
    European journal of clinical pharmacology, 2004, Volume: 60, Issue:1

    Topics: Adult; Benzodiazepines; Biperiden; Chlorpromazine; Clozapine; Cyclohexanols; Diazepam; Drug Administration Schedule; Drug Prescriptions; Drug Therapy, Combination; Drug Utilization Review; Europe; Female; Humans; Male; Mood Disorders; Olanzapine; Pharmacoepidemiology; Practice Patterns, Physicians'; Psychiatric Department, Hospital; Psychotropic Drugs; Schizophrenia; Time Factors; Venlafaxine Hydrochloride

2004
Antipsychotics increase microtubule-associated protein 2 mRNA but not spinophilin mRNA in rat hippocampus and cortex.
    Journal of neuroscience research, 2004, May-01, Volume: 76, Issue:3

    Topics: Animals; Antipsychotic Agents; Benzodiazepines; Cerebral Cortex; Chlorpromazine; Clozapine; Gene Expression Regulation; Haloperidol; Hippocampus; In Situ Hybridization; Male; Microfilament Proteins; Microtubule-Associated Proteins; Nerve Tissue Proteins; Neurites; Olanzapine; Rats; Rats, Sprague-Dawley; Risperidone; RNA, Messenger; Tissue Distribution

2004
More powerful two-sample tests for differences in repeated measures of adverse effects in psychiatric trials when only some patients may be at risk.
    Statistics in medicine, 2005, Jan-15, Volume: 24, Issue:1

    Topics: Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Chlorpromazine; Computer Simulation; Data Interpretation, Statistical; Double-Blind Method; Humans; Olanzapine; Psychiatry; Randomized Controlled Trials as Topic; Schizophrenia

2005
Body weight gain induced by a newer antipsychotic agent reversed as negative symptoms improved.
    Acta psychiatrica Scandinavica, 2005, Volume: 112, Issue:1

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Diet; Exercise; Female; Haloperidol; Humans; Olanzapine; Schizophrenia; Weight Gain

2005
Effect of switching antipsychotics on antiparkinsonian medication use in schizophrenia: population-based study.
    The British journal of psychiatry : the journal of mental science, 2005, Volume: 187

    Topics: Adult; Age Factors; Aged; Antiparkinson Agents; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Chlorpromazine; Dopamine Antagonists; Drug Administration Schedule; Family Practice; Female; Haloperidol; Humans; Male; Middle Aged; Olanzapine; Risperidone; Schizophrenia; Sex Factors

2005
Second-generation antipsychotic drugs, olanzapine, quetiapine, and clozapine enhance neurite outgrowth in PC12 cells via PI3K/AKT, ERK, and pertussis toxin-sensitive pathways.
    Journal of molecular neuroscience : MN, 2005, Volume: 27, Issue:1

    Topics: Animals; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Chromones; Clozapine; Dibenzothiazepines; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Fluphenazine; Haloperidol; Humans; Morpholines; Nerve Growth Factor; Neurites; Olanzapine; PC12 Cells; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Quetiapine Fumarate; Rats

2005
Differential effects of long-term treatment with typical and atypical antipsychotics on NGF and BDNF levels in rat striatum and hippocampus.
    Schizophrenia research, 2006, Feb-15, Volume: 82, Issue:1

    Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain-Derived Neurotrophic Factor; Chlorpromazine; Corpus Striatum; Haloperidol; Hippocampus; Male; Nerve Growth Factor; Olanzapine; Rats; Rats, Wistar; Risperidone; Time

2006
In vitro toxicity of clozapine, olanzapine, and quetiapine on granulocyte-macrophage progenitors (GM-CFU).
    Pharmacopsychiatry, 2006, Volume: 39, Issue:1

    Topics: Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clozapine; Colony-Forming Units Assay; Dibenzothiazepines; Dose-Response Relationship, Drug; Granulocytes; Hematopoietic Stem Cells; Humans; Macrophages; Olanzapine; Quetiapine Fumarate

2006
Long-term antipsychotic treatments and crossover studies in rats: differential effects of typical and atypical agents on the expression of antioxidant enzymes and membrane lipid peroxidation in rat brain.
    Journal of psychiatric research, 2007, Volume: 41, Issue:5

    Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain; Chlorpromazine; Clozapine; Cross-Over Studies; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Haloperidol; Lipid Peroxidation; Male; Membrane Lipids; Olanzapine; Rats; Rats, Wistar; Risperidone; Schizophrenia; Superoxide Dismutase

2007
The rational use of medications in acute psychotic presentations -- the case for less is more.
    Journal of psychiatry & neuroscience : JPN, 2006, Volume: 31, Issue:3

    Topics: Adult; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clopenthixol; Humans; Male; Olanzapine; Psychotic Disorders; Valproic Acid

2006
Chlorpromazine, clozapine and olanzapine inhibit anionic amino acid transport in cultured human fibroblasts.
    Amino acids, 2006, Volume: 31, Issue:2

    Topics: Amino Acid Transport Systems, Acidic; Amino Acids; Antipsychotic Agents; Benzodiazepines; Biological Transport; Cells, Cultured; Chlorpromazine; Clozapine; Fibroblasts; Humans; Olanzapine

2006
Classification of antipsychotic drugs by gene expression in the frontal cortex of mice.
    Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 2006, Volume: 26, Issue:2

    Topics: Animals; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Cluster Analysis; Dibenzothiazepines; Frontal Lobe; Gene Expression; Male; Mice; Olanzapine; Quetiapine Fumarate; Thioridazine

2006
Evaluation of antipsychotic drugs as inhibitors of multidrug resistance transporter P-glycoprotein.
    Psychopharmacology, 2006, Volume: 187, Issue:4

    Topics: Animals; Antipsychotic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzodiazepines; Chlorpromazine; Clozapine; Cyclosporins; Dibenzothiazepines; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Flow Cytometry; Fluorescent Dyes; Haloperidol; Isoxazoles; Kidney; Liver; LLC-PK1 Cells; Olanzapine; Paliperidone Palmitate; Pyrimidines; Quetiapine Fumarate; Rhodamine 123; Risperidone; Swine; Transfection

2006
Reduced thalamic volume in patients with chronic schizophrenia after switching from typical antipsychotic medications to olanzapine.
    The American journal of psychiatry, 2006, Volume: 163, Issue:11

    Topics: Adult; Antipsychotic Agents; Atrophy; Benzodiazepines; Chlorpromazine; Chronic Disease; Female; Follow-Up Studies; Humans; Hypertrophy; Longitudinal Studies; Magnetic Resonance Imaging; Male; Olanzapine; Schizophrenia; Thalamus; Therapeutic Equivalency

2006
Relative risk of glucose elevation during antipsychotic exposure in a Veterans Administration population.
    International clinical psychopharmacology, 2007, Volume: 22, Issue:1

    Topics: Antipsychotic Agents; Benzodiazepines; Blood Glucose; Chlorpromazine; Cohort Studies; Female; Fluphenazine; Haloperidol; Hospitals, Veterans; Humans; Hyperglycemia; Incidence; Male; Middle Aged; Olanzapine; Perphenazine; Retrospective Studies; Risk Assessment; Risk Factors; Risperidone; Southeastern United States; Time Factors; Veterans

2007
Risk of death associated with antipsychotic drug dispensing in residential aged care facilities.
    The Australian and New Zealand journal of psychiatry, 2007, Volume: 41, Issue:9

    Topics: Aged; Anticonvulsants; Antipsychotic Agents; Australia; Benzodiazepines; Carbamazepine; Cause of Death; Chlorpromazine; Comorbidity; Cross-Sectional Studies; Death, Sudden; Female; Haloperidol; Homes for the Aged; Humans; Male; Nursing Homes; Olanzapine; Risk; Valproic Acid; Veterans

2007
Antipsychotic medication dispensing and risk of death in veterans and war widows 65 years and older.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2007, Volume: 15, Issue:11

    Topics: Age Factors; Aged; Aged, 80 and over; Anticonvulsants; Antipsychotic Agents; Australia; Benzodiazepines; Carbamazepine; Cause of Death; Chlorpromazine; Cohort Studies; Dementia; Female; Haloperidol; Humans; Male; Mortality; Olanzapine; Proportional Hazards Models; Retrospective Studies; Risk; Risk Factors; Survival Rate; Valproic Acid; Veterans; Widowhood

2007
Exploring genetic variations that may be associated with the direct effects of some antipsychotics on lipid levels.
    Schizophrenia research, 2008, Volume: 98, Issue:1-3

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Cross-Sectional Studies; Dibenzothiazepines; Female; Gene Frequency; Genetic Variation; Genotype; Humans; Hypercholesterolemia; Hyperlipidemias; Hypertriglyceridemia; Lipids; Male; Olanzapine; Oligonucleotide Array Sequence Analysis; Pharmacogenetics; Polymorphism, Single Nucleotide; Psychotic Disorders; Quetiapine Fumarate; Randomized Controlled Trials as Topic

2008
Preliminary findings from the National Register of Antipsychotic Medication in Pregnancy.
    The Australian and New Zealand journal of psychiatry, 2008, Volume: 42, Issue:1

    Topics: Adult; Antipsychotic Agents; Australia; Benzodiazepines; Chlorpromazine; Cross-Sectional Studies; Data Collection; Female; Humans; Infant, Newborn; Olanzapine; Phenytoin; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications; Psychotic Disorders; Registries; Risk Factors; Substance Withdrawal Syndrome; Suicide

2008
The clinical dilemma--prescribing in pregnancy.
    Psychiatria Danubina, 2008, Volume: 20, Issue:1

    Topics: Abnormalities, Drug-Induced; Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Chlorpromazine; Female; Hand Deformities, Congenital; Humans; Infant, Newborn; Lithium Carbonate; Olanzapine; Pregnancy; Pregnancy Complications; Risk Assessment; Schizophrenia, Disorganized

2008
Atypical neuroleptic malignant syndrome in an adolescent.
    Journal of child and adolescent psychopharmacology, 2008, Volume: 18, Issue:2

    Topics: Administration, Oral; Adolescent; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Diagnosis, Differential; Dibenzothiazepines; Drug Therapy, Combination; Humans; Injections, Intramuscular; Male; Neuroleptic Malignant Syndrome; Olanzapine; Paranoid Disorders; Quetiapine Fumarate

2008
Neuroleptic malignant syndrome and catatonia in a patient with dementia.
    The Australian and New Zealand journal of psychiatry, 2008, Volume: 42, Issue:6

    Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Catatonia; Chlorpromazine; Cholinesterase Inhibitors; Cognition Disorders; Creatine Kinase; Dementia; Disease Progression; Donepezil; Female; Humans; Indans; Lorazepam; Muscle Rigidity; Neuroleptic Malignant Syndrome; Olanzapine; Piperidines; Recurrence; Risperidone

2008
Negative effects of chronic oral chlorpromazine and olanzapine treatment on the performance of tasks designed to assess spatial learning and working memory in rats.
    Neuroscience, 2008, Oct-28, Volume: 156, Issue:4

    Topics: Administration, Oral; Analysis of Variance; Animals; Antipsychotic Agents; Area Under Curve; Behavior, Animal; Benzodiazepines; Chlorpromazine; Dose-Response Relationship, Drug; Drug Administration Schedule; Exploratory Behavior; Hand Strength; Male; Maze Learning; Memory, Short-Term; Motor Activity; Olanzapine; Rats; Rats, Wistar; Reaction Time; Space Perception

2008
Neuroleptic malignant syndrome developing after acute overdose with olanzapine and chlorpromazine.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2009, Volume: 5, Issue:1

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bromocriptine; Chlorpromazine; Citalopram; Combined Modality Therapy; Dopamine Agonists; Drug Overdose; Female; Humans; Hypnotics and Sedatives; Hypothermia, Induced; Infusions, Intravenous; Midazolam; Neuroleptic Malignant Syndrome; Olanzapine; Respiration, Artificial; Treatment Outcome

2009
In response to Morris et al.'s "Neuroleptic malignant syndrome developing after acute overdose with olanzapine and chlorpromazine".
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2009, Volume: 5, Issue:4

    Topics: Antipsychotic Agents; Benzodiazepines; Bromocriptine; Chlorpromazine; Disease Progression; Dopamine Agonists; Drug Overdose; Humans; Neuroleptic Malignant Syndrome; Olanzapine; Serotonin Receptor Agonists; Treatment Outcome

2009
Acute respiratory distress due to antipsychotic drugs.
    Pharmacopsychiatry, 2010, Volume: 43, Issue:3

    Topics: Adult; Antiparkinson Agents; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Drug Therapy, Combination; Dystonia; Fatal Outcome; Haloperidol; Humans; Larynx; Male; Olanzapine; Respiratory Distress Syndrome; Respiratory Insufficiency; Risperidone; Schizophrenia

2010
pH-dependent interaction of psychotropic drug with glycerophospholipid monolayers studied by the Langmuir technique.
    Biophysical chemistry, 2010, Volume: 152, Issue:1-3

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Benzodiazepines; Chlorpromazine; Glycerophospholipids; Hydrogen-Ion Concentration; Olanzapine; Phosphatidylcholines; Phosphatidylserines; Psychotropic Drugs; Temperature

2010
The use of Pro Re Nata or Statim medications for behavioral control: a summary of experience at a tertiary care children's mental health center.
    Journal of child and adolescent psychopharmacology, 2011, Volume: 21, Issue:1

    Topics: Adolescent; Age Factors; Aggression; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Child; Chlorpromazine; Diagnosis, Dual (Psychiatry); Drug Administration Schedule; Female; Humans; Intellectual Disability; Length of Stay; Lorazepam; Male; Mental Disorders; Mental Health Services; Olanzapine; Practice Patterns, Physicians'; Prospective Studies; Sex Factors

2011
In vivo 5-HT(6) receptor occupancy by antipsychotic drugs in the rat brain.
    Neuroscience letters, 2011, Oct-10, Volume: 503, Issue:3

    Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain; Chlorpromazine; Clozapine; Dose-Response Relationship, Drug; Male; Olanzapine; Piperazines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Sulfonamides

2011
The pharmacoepidemiology of antipsychotics for adults with schizophrenia in Canada, 2005 to 2009.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2011, Volume: 56, Issue:10

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Canada; Chlorpromazine; Clopenthixol; Clozapine; Female; Flupenthixol; Humans; Loxapine; Male; Olanzapine; Pharmacoepidemiology; Schizophrenia

2011
On the mechanism of action of antipsychotic drugs: a chemical reaction not receptor blockade.
    Current drug discovery technologies, 2013, Volume: 10, Issue:3

    Topics: Adrenochrome; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Hydrogen-Ion Concentration; Iodine; Minocycline; Olanzapine; Polymerization; Sodium Chloride; Temperature

2013
Risk of ischemic stroke associated with the use of antipsychotic drugs in elderly patients: a retrospective cohort study in Korea.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Aged; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Cohort Studies; Dose-Response Relationship, Drug; Female; Haloperidol; Humans; Male; Olanzapine; Proportional Hazards Models; Quetiapine Fumarate; Republic of Korea; Retrospective Studies; Risk; Stroke; Time Factors

2015
Effect of short and long-term treatment with antipsychotics on orexigenic/anorexigenic neuropeptides expression in the rat hypothalamus.
    Neuropeptides, 2015, Volume: 51

    Topics: alpha-MSH; Animals; Antipsychotic Agents; Benzodiazepines; Calcium-Binding Proteins; Chlorpromazine; DNA-Binding Proteins; Drug Administration Schedule; Haloperidol; Hypothalamus; Male; Nerve Tissue Proteins; Neuropeptide Y; Nucleobindins; Olanzapine; Orexin Receptors; Orexins; Pro-Opiomelanocortin; Rats; Rats, Sprague-Dawley; Receptor, Melanocortin, Type 4; Receptors, G-Protein-Coupled; Receptors, Neuropeptide

2015
A Cost-effectiveness Analysis of Antipsychotics for Treatment of Schizophrenia in Uganda.
    Applied health economics and health policy, 2015, Volume: 13, Issue:5

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Cost-Benefit Analysis; Drug Costs; Haloperidol; Health Care Costs; Humans; Middle Aged; Olanzapine; Quality-Adjusted Life Years; Risperidone; Schizophrenia; Uganda

2015
Metabotropic glutamate receptor 5, and its trafficking molecules Norbin and Tamalin, are increased in the CA1 hippocampal region of subjects with schizophrenia.
    Schizophrenia research, 2015, Volume: 166, Issue:1-3

    Topics: Animals; Antipsychotic Agents; Benzodiazepines; CA1 Region, Hippocampal; Carrier Proteins; Chlorpromazine; Dimerization; Female; Haloperidol; Humans; Immunoblotting; Male; Membrane Proteins; Middle Aged; Nerve Tissue Proteins; Neuropeptides; Olanzapine; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Schizophrenia

2015
Neuroleptics Affect Neuropeptide S and NPSR mRNA Levels in the Rat Brain.
    Journal of molecular neuroscience : MN, 2015, Volume: 57, Issue:3

    Topics: Animals; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Corpus Striatum; Dopamine; Gene Expression Regulation; Hippocampus; Hypothalamus; Male; Neuropeptides; Olanzapine; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptors, Dopamine; Receptors, Neuropeptide; RNA, Messenger

2015
Effects of neuroleptics administration on adult neurogenesis in the rat hypothalamus.
    Pharmacological reports : PR, 2015, Volume: 67, Issue:6

    Topics: Animals; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Doublecortin Protein; Haloperidol; Hypothalamus; Male; Neurogenesis; Neurons; Olanzapine; Rats

2015
A Case Report: Anti-Psychotic Agents Related Ocular Toxicity.
    Medicine, 2016, Volume: 95, Issue:15

    Topics: Aged; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Eye Diseases; Female; Humans; Olanzapine; Schizophrenia

2016
A sensitive capillary LC-UV method for the simultaneous analysis of olanzapine, chlorpromazine and their FMO-mediated N-oxidation products in brain microdialysates.
    Talanta, 2017, Jan-01, Volume: 162

    Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain; Chlorpromazine; Chromatography, High Pressure Liquid; Dialysis Solutions; Male; Microdialysis; Olanzapine; Oxidation-Reduction; Oxides; Oxygenases; Rats, Wistar; Reproducibility of Results

2017
Risperidone versus olanzapine in the acute treatment of Persistent Delusional Disorder: A retrospective analysis.
    Psychiatry research, 2017, Volume: 253

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Female; Humans; Logistic Models; Male; Middle Aged; Olanzapine; Prospective Studies; Retrospective Studies; Risperidone; Schizophrenia, Paranoid; Treatment Outcome

2017
Butyl Methacrylate-Co-Ethylene Glycol Dimethacrylate Monolith for Online in-Tube SPME-UHPLC-MS/MS to Determine Chlopromazine, Clozapine, Quetiapine, Olanzapine, and Their Metabolites in Plasma Samples.
    Molecules (Basel, Switzerland), 2019, Jan-16, Volume: 24, Issue:2

    Topics: Antipsychotic Agents; Chlorpromazine; Chromatography, High Pressure Liquid; Clozapine; Humans; Metabolomics; Olanzapine; Quetiapine Fumarate; Schizophrenia; Solid Phase Microextraction; Tandem Mass Spectrometry

2019
Serotonin 2A (5-HT
    Scientific reports, 2020, 12-10, Volume: 10, Issue:1

    Topics: Amphetamines; Animals; Antipsychotic Agents; Cell-Matrix Junctions; Chlorpromazine; HEK293 Cells; Humans; Mental Disorders; Olanzapine; Rats; Receptor, Serotonin, 5-HT2A; Risperidone; Serotonin; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Stress Fibers

2020
Inhibitory Effects of Antipsychotics on the Contractile Response to Acetylcholine in Rat Urinary Bladder Smooth Muscles.
    Biological & pharmaceutical bulletin, 2021, Volume: 44, Issue:8

    Topics: Acetylcholine; Aging; Animals; Antipsychotic Agents; Chlorpromazine; Cholinergic Antagonists; Clozapine; Dibenzothiepins; Male; Mental Disorders; Methotrimeprazine; Muscle Contraction; Muscle, Smooth; Olanzapine; Quetiapine Fumarate; Rats, Wistar; Urinary Bladder; Urologic Diseases

2021
Letter to the Editor: Rethinking The Cost Of Antipsychotic Treatment: The Average Cost Of The Drugs Used In Turkey In 2020.
    Turk psikiyatri dergisi = Turkish journal of psychiatry, 2022,Summer, Volume: 33, Issue:2

    Topics: Adenosine Monophosphate; Adult; Amisulpride; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Chlorpromazine; Clopenthixol; Clozapine; Flupenthixol; Fluphenazine; Haloperidol; Humans; Olanzapine; Paliperidone Palmitate; Pharmaceutical Preparations; Pimozide; Quetiapine Fumarate; Risperidone; Sulpiride; Trifluoperazine

2022
Risk factors for abnormal glucose metabolism during antipsychotic treatment: A prospective cohort study.
    Journal of psychiatric research, 2023, Volume: 168

    Topics: Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clozapine; Cohort Studies; Glucose; Humans; Hypertriglyceridemia; Obesity; Olanzapine; Prospective Studies; Risk Factors

2023