chlorpromazine and nortriptyline

chlorpromazine has been researched along with nortriptyline in 84 studies

Research

Studies (84)

TimeframeStudies, this research(%)All Research%
pre-199059 (70.24)18.7374
1990's2 (2.38)18.2507
2000's9 (10.71)29.6817
2010's14 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Chiang, GH; Unger, SH1
Horvath, D1
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Bergström, F; Giordanetto, F; Rehngren, M; Tunek, A; Wan, H1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Lombardo, F; Obach, RS; Waters, NJ1
Ahman, M; Holmén, AG; Wan, H1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Glen, RC; Lowe, R; Mitchell, JB1
Gozalbes, R; Pineda-Lucena, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F1
Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Dalvie, D; Loi, CM; Smith, DA1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Modestin, J; Petrin, A1
Houghton, GW; Richens, A1
Davis, CM; Fenimore, DC; Meyer, CJ1
Stewart, MJ; Watson, ID1
Davis, CM; Fenimore, DC; Hsu, F; Meyer, CJ; Zlatkis, A1
Henry, BW; Overall, JE; Woodward, JA1
Oksenkrug, GF1
Chestnut, EC; Cooper, TB; Farooki, ZQ; Geller, B1
Frisk-Holmberg, M; van der Kleijn, E1
Tuomisto, J1
Zingales, I1
Roberts, E; Simonsen, DG1
König, J; Mlejnkovà, M; Rysànek, K; Spànkovà, H1
Tuck, JR1
Gaut, ZN2
Mlejnkova, M; Rysánek, K; Spánkova, H; Synek, P1
Brittain, RT1
Garattini, S; Jori, A; Paglialunga, S1
Bevegård, S; Thorstrand, C1
Karobath, M1
Horn, AS; Trace, RC1
Christiansen, J; Gram, LF; Overo, KF1
Gripenberg, J1
König, J; Mlejnková, M; Rysánek, K; Spánková, H; Synek, P1
Connor, JD; Crawford, IL; Pardridge, WM1
Boulu, R; Dupeyron, JP; Rossignol, P1
Schumacher, GE; Weiner, J1
Mattila, MJ; Saarnivaara, L1
Furlong, FW; Luby, ED1
Gram, LF; Overo, KF1
Oates, JA; Shand, DG1
Hrbek, J; Navrátil, J1
Ahonen, A; Pentilä, A1
Rohte, O2
Gross, R; Linker, H; Reuter, H1
Núnek, K1
Jones, BJ; Roberts, DJ; Tolman, BD1
Horioka, T; Kaneko, H; Masuda, Y; Murai, K; Nakamura, H1
Lorenz, D1
Hammar, CG1
Kaeser, HE1
Dingell, JV; Miller, KW1
Kraft, IA1
Ashford, A; Ross, JW1
Ahtee, L; Paasonen, MK1
Milner, G1
Henderson, JK; Redman, CE; Stark, P; Turk, JA1
Hollister, LE; Kimbell, I; Overall, JE; Shelton, J1
Capitanucci, P; Fioretti, MC1
Carter, CH1
Angel, C; Roberts, AJ1
Schechter, MD1
Coyle, JT; Tune, L1
Bianchetti, G; Dugas, M; Morselli, PL1
Adamczyk, M; Fishpaugh, J; Harrington, C; Hartter, D; Johnson, D; Vanderbilt, A1
METYS, J; METYSOVA, J; VOTAVA, Z1

Reviews

3 review(s) available for chlorpromazine and nortriptyline

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Correlation between plasma concentration and clinical effect of neuroleptics and antidepressants].
    International journal of clinical pharmacology and biopharmacy, 1976, Volume: 13, Issue:1

    Topics: Amitriptyline; Antidepressive Agents; Antipsychotic Agents; Chlorpromazine; Clozapine; Desipramine; Dibenzazepines; Dose-Response Relationship, Drug; Fluphenazine; Humans; Imipramine; Nortriptyline; Perazine; Phenelzine; Thioridazine

1976

Trials

1 trial(s) available for chlorpromazine and nortriptyline

ArticleYear
Lithium in the control of mania.
    International journal of neuropsychiatry, 1967, Volume: 3, Issue:4

    Topics: Adult; Amitriptyline; Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Desipramine; Female; Humans; Imipramine; Lithium; Male; Middle Aged; Nortriptyline; Thioridazine; Tranylcypromine; Trifluoperazine

1967

Other Studies

80 other study(ies) available for chlorpromazine and nortriptyline

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:3

    Topics: Amines; Animals; Buffers; Chromatography, High Pressure Liquid; Histamine Release; Lipid Metabolism; Octanols; Protein Binding; Rats; Serum Albumin, Bovine; Sodium-Potassium-Exchanging ATPase; Solubility; Structure-Activity Relationship

1981
A virtual screening approach applied to the search for trypanothione reductase inhibitors.
    Journal of medicinal chemistry, 1997, Jul-18, Volume: 40, Issue:15

    Topics: Algorithms; Databases, Factual; Enzyme Inhibitors; Models, Chemical; Molecular Conformation; NADH, NADPH Oxidoreductases; Thermodynamics

1997
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
High-throughput screening of drug-brain tissue binding and in silico prediction for assessment of central nervous system drug delivery.
    Journal of medicinal chemistry, 2007, Sep-20, Volume: 50, Issue:19

    Topics: Animals; Brain; Central Nervous System Agents; Dialysis; Hydrophobic and Hydrophilic Interactions; In Vitro Techniques; Mice; Models, Statistical; Protein Binding; Quantitative Structure-Activity Relationship; Rats

2007
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution

2011
Species independence in brain tissue binding using brain homogenates.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Which metabolites circulate?
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:5

    Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Inhibition of phenytoin metabolism by other drugs used in epilepsy.
    International journal of clinical pharmacology and biopharmacy, 1975, Volume: 12, Issue:1-2

    Topics: Adult; Aged; Chloramphenicol; Chlorpromazine; Depression, Chemical; Drug Interactions; Epilepsy; Half-Life; Humans; Kinetics; Male; Nortriptyline; Phenylbutyrates; Phenytoin; Thiazines; Urea

1975
Determination of drugs in plasma by high-performance thin-layer chromatography.
    Clinical chemistry, 1978, Volume: 24, Issue:8

    Topics: Amitriptyline; Chlorpromazine; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Desipramine; Humans; Imipramine; Nortriptyline; Phenobarbital; Phenytoin; Psychotropic Drugs; Spectrophotometry, Ultraviolet

1978
Assay of tricyclic structured drugs and their metabolites in urine by high-performance liquid chromatography.
    Journal of chromatography, 1977, Apr-01, Volume: 134, Issue:1

    Topics: Amitriptyline; Chlorpromazine; Chromatography, High Pressure Liquid; Dibenzocycloheptenes; Humans; Imipramine; Nortriptyline; Protriptyline

1977
High-performance thin-layer chromatographic determination of psychopharmacologic agents in blood serum.
    Journal of chromatography, 1977, Nov-11, Volume: 142

    Topics: Amitriptyline; Chlorpromazine; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Desipramine; Humans; Imipramine; Methods; Nortriptyline; Psychotropic Drugs; Spectrophotometry, Ultraviolet

1977
Patterns of symptom change in anxious depressed outpatients treated with different drugs.
    Diseases of the nervous system, 1975, Volume: 36, Issue:3

    Topics: Amitriptyline; Antidepressive Agents; Anxiety; Chlordiazepoxide; Chlorpromazine; Depression; Desipramine; Diazepam; Drug Combinations; Fluphenazine; Humans; Imipramine; Mental Disorders; Nortriptyline; Perphenazine; Thioridazine; Thiothixene; Tranquilizing Agents; Trifluoperazine

1975
[Effect of prothixen and related compounds on serotonin absorption by human thrombocytes].
    Biulleten' eksperimental'noi biologii i meditsiny, 1975, Volume: 80, Issue:8

    Topics: Absorption; Amitriptyline; Biological Transport; Blood Platelets; Cell Membrane Permeability; Chlorpromazine; Clomipramine; Depression, Chemical; Desipramine; Humans; Imipramine; In Vitro Techniques; Nortriptyline; Serotonin; Structure-Activity Relationship; Thioxanthenes; Triazines

1975
Dose and plasma levels of nortriptyline and chlorpromazine in delusionally depressed adolescents and of nortriptyline in nondelusionally depressed adolescents.
    The American journal of psychiatry, 1985, Volume: 142, Issue:3

    Topics: Adolescent; Child; Chlorpromazine; Delusions; Depressive Disorder; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Nortriptyline; Psychiatric Status Rating Scales

1985
The relationship between the lipophilic nature of tricyclic neuroleptics and antidepressants, and histamine release.
    European journal of pharmacology, 1972, Volume: 18, Issue:2

    Topics: Amitriptyline; Animals; Antidepressive Agents; Cell Membrane Permeability; Chemical Phenomena; Chemistry; Chlorpromazine; Chlorprothixene; Clopenthixol; Desipramine; Fluphenazine; Histamine Release; Imipramine; Kinetics; Male; Mast Cells; Methotrimeprazine; Nortriptyline; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Rats; Solvents; Structure-Activity Relationship; Thioridazine; Tranquilizing Agents; Trifluoperazine

1972
A new modification for studying 5-HT uptake by blood platelets: a re-evaluation of tricyclic antidepressants as uptake inhibitors.
    The Journal of pharmacy and pharmacology, 1974, Volume: 26, Issue:2

    Topics: Amitriptyline; Animals; Blood Platelets; Carbon Radioisotopes; Chlorpromazine; Desipramine; Dibenzazepines; Doxepin; Imipramine; In Vitro Techniques; Kinetics; Models, Biological; Nortriptyline; Promazine; Rabbits; Serotonin; Synaptosomes; Temperature; Trifluoperazine; Triflupromazine

1974
Systematic identification of psychotropic drugs by thin layer chromatography. II.
    Journal of chromatography, 1968, Mar-26, Volume: 34, Issue:1

    Topics: Amitriptyline; Chlorpromazine; Chlorprothixene; Chromatography, Thin Layer; Desipramine; Female; Humans; Imipramine; Male; Meprobamate; Nortriptyline; Phenothiazines; Schizophrenia; Silicon Dioxide; Thioridazine; Tranquilizing Agents

1968
Some properties of cyclic 3',5'-nucleotide phosphodiesterase of mouse brain: effects of imidazole-4-acetic acid, chlorpromazine, cyclic 3',5'-GMP, and other substances.
    Brain research, 1970, Nov-11, Volume: 24, Issue:1

    Topics: Acetates; Animals; Brain; Chlorpromazine; Cyclic AMP; Guanine Nucleotides; Imidazoles; Magnesium; Mice; Nortriptyline; Nucleosides; Phosphates; Phosphoric Monoester Hydrolases; Purines; Pyrimidines; Theophylline

1970
Effect of tricyclic antidepressants on phosphodiesterase. Correlation between aggregability and thrombocyte metabolism.
    Activitas nervosa superior, 1973, Volume: 15, Issue:2

    Topics: Antidepressive Agents; Blood Platelets; Chlorpromazine; Dibenzothiepins; Imipramine; Nortriptyline; Phosphoric Diester Hydrolases; Platelet Adhesiveness; Serotonin

1973
Effects of chlorpromazine, thioridazine and haloperidol on adrenergic transmitter mechanisms in man.
    European journal of clinical pharmacology, 1973, Volume: 6, Issue:2

    Topics: Animals; Biological Transport, Active; Blood Pressure; Cell Membrane; Chlorpromazine; Drug Interactions; Haloperidol; Humans; In Vitro Techniques; Iris; Norepinephrine; Nortriptyline; Phentolamine; Rats; Receptors, Adrenergic; Sympathetic Nervous System; Synaptic Transmission; Thioridazine; Tritium; Tyramine

1973
Influence of various substances which induce and inhibit aggregation on the uptake of deoxyglucose by human blood platelets.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 190, Issue:1

    Topics: Adenosine Diphosphate; Amitriptyline; Antidepressive Agents; Blood Glucose; Blood Platelets; Bucladesine; Carbon Radioisotopes; Chlorpromazine; Cyproheptadine; Desipramine; Epinephrine; Glucose; Humans; In Vitro Techniques; Norepinephrine; Nortriptyline; Platelet Adhesiveness; Promethazine; Serotonin; Thrombin

1974
Effect of drugs on the activity of thrombocytes 3,5-cyclic AMP phosphodiesterase.
    International journal of clinical pharmacology, therapy and toxicology, 1974, Volume: 10, Issue:1

    Topics: 1-Propanol; Adenosine Diphosphate; Adenosine Monophosphate; Aminophylline; Blood Platelets; Caffeine; Chlorpromazine; Cyclic AMP; Desipramine; Dibenzothiepins; Epinephrine; Imipramine; Nortriptyline; Phosphoric Diester Hydrolases; Piperazines; Platelet Adhesiveness

1974
The intracerebral effects of noradrenaline and its modification by drugs in the mouse.
    The Journal of pharmacy and pharmacology, 1966, Volume: 18, Issue:9

    Topics: Amitriptyline; Animals; Antidepressive Agents; Ataxia; Atropine; Body Temperature; Brain; Central Nervous System; Chlordiazepoxide; Chlorpheniramine; Chlorpromazine; Diazepam; Drug Antagonism; Haloperidol; Histamine H1 Antagonists; Imipramine; Male; Mice; Norepinephrine; Nortriptyline; Pentobarbital; Phenytoin; Piperazines; Trihexyphenidyl

1966
Effect of antidepressant and adrenergic blocking drugs on hyperthermia induced by reserpine.
    Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 165, Issue:2

    Topics: Amitriptyline; Animals; Antidepressive Agents; Atropine; Body Temperature; Chlorisondamine; Chlorpromazine; Desipramine; Ethanolamines; Female; Fever; Hydrazines; Imipramine; Monoamine Oxidase Inhibitors; Norepinephrine; Nortriptyline; Phenoxybenzamine; Phentolamine; Propranolol; Rats; Reserpine; Sympatholytics; Tetrabenazine

1967
Central hemodynamics in severe poisoning by hypnotic drugs. Coma depth and body temperature.
    Acta medica Scandinavica, 1972, Volume: 191, Issue:4

    Topics: Adult; Aged; Amitriptyline; Blood Pressure; Body Temperature; Cardiac Output; Central Venous Pressure; Chlorpromazine; Chlorprothixene; Coma; Dibenzazepines; Female; Glutethimide; Heart Rate; Hemodynamics; Humans; Hypnotics and Sedatives; Male; Middle Aged; Nortriptyline; Oxygen Consumption; Pentobarbital; Phenothiazines; Tranquilizing Agents; Vascular Resistance

1972
[Tricyclic anti-depressant drugs and dopamine sensitive adenylcyclase from rat caudate nuclei].
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:7

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Amitriptyline; Animals; Antidepressive Agents; Basal Metabolism; Caudate Nucleus; Chlorpromazine; Desipramine; Dopamine; Imipramine; Nortriptyline; Rats; Stimulation, Chemical

1974
Structure-activity relations for the inhibition of 5-hydroxytryptamine uptake by tricyclic antidepressants into synaptosomes from serotoninergic neurones in rat brain homogenates.
    British journal of pharmacology, 1974, Volume: 51, Issue:3

    Topics: Amitriptyline; Animals; Antidepressive Agents; Brain Chemistry; Chlorpromazine; Hypothalamus; Imipramine; In Vitro Techniques; Iprindole; Methylation; Neurons; Nortriptyline; Promazine; Rats; Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Synaptosomes

1974
Pharmacokinetic interaction between neuroleptics and tricyclic antidepressants in the rat.
    Acta pharmacologica et toxicologica, 1974, Volume: 35, Issue:3

    Topics: Animals; Brain; Carbon Radioisotopes; Chlorpromazine; Chromatography, Thin Layer; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Erythrocytes; Feces; Glucuronates; Heart; Imipramine; Injections, Intraperitoneal; Male; Nortriptyline; Perphenazine; Rats

1974
Incorporation of imipramine into isolated rat peritoneal mast cells in vitro.
    Acta physiologica Scandinavica, 1974, Volume: 92, Issue:1

    Topics: 5-Hydroxytryptophan; Amitriptyline; Animals; Binding Sites; Calcium; Cell Membrane Permeability; Chlorpromazine; Cocaine; Depression, Chemical; Desipramine; Dibenzazepines; Female; Guanethidine; Hydrogen-Ion Concentration; Imipramine; Leukocytes; Male; Mast Cells; Nortriptyline; Rats; Receptors, Drug; Reserpine; Serotonin; Temperature

1974
Relationship between substances strengthening of the thrombocyte cell membrane on the aggregation of thrombocytes and on the uptake and release of serotonin.
    Acta Universitatis Carolinae. Medica. Monographia, 1972, Volume: 53

    Topics: Adenosine Diphosphate; Amitriptyline; Benzothiepins; Blood Platelets; Cell Membrane; Cell Membrane Permeability; Chlorpromazine; Colorimetry; Desipramine; Epinephrine; Humans; Imipramine; In Vitro Techniques; Nortriptyline; Phentolamine; Piperazines; Platelet Adhesiveness; Propranolol; Receptors, Adrenergic; Serotonin; Serotonin Antagonists; Spectrometry, Fluorescence; Tranquilizing Agents

1972
Binding of cyproheptadine-(N-methyl- 14 C) by human blood platelets: inhibition by phenothiazines and tricyclic antidepressants.
    The Journal of pharmacology and experimental therapeutics, 1973, Volume: 185, Issue:1

    Topics: Amitriptyline; Blood Platelets; Carbon Isotopes; Centrifugation; Chlorpromazine; Cyproheptadine; Desipramine; Humans; Imipramine; In Vitro Techniques; Nortriptyline; Phenothiazines; Platelet Adhesiveness; Promethazine

1973
Permeability changes in the blood-brain barrier induced by nortriptyline and chlorpromazine.
    Toxicology and applied pharmacology, 1973, Volume: 26, Issue:1

    Topics: Amitriptyline; Animals; Autoradiography; Blood-Brain Barrier; Brain; Capillaries; Carbon Radioisotopes; Cell Membrane Permeability; Cerebral Cortex; Chlorpromazine; Desipramine; Diphenhydramine; Dopamine; Imipramine; In Vitro Techniques; Inulin; Male; Mannitol; Molecular Weight; Nortriptyline; Rats; Tritium

1973
[Evaluation of central antireserpine effect by the use of light blink reflex (author's transl)].
    Psychopharmacologia, 1973, Oct-23, Volume: 33, Issue:1

    Topics: Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Chlorpromazine; Chlorprothixene; Desipramine; Dibenzazepines; Dibenzocycloheptenes; Diethylamines; Dimethylamines; Ethylenediamines; Glycolates; Imipramine; Light; Nortriptyline; Propylamines; Rabbits; Reflex; Reserpine

1973
Practical pharmacokinetic techniques for drug consultation and evaluation. 3. Psychotherapeutic drugs as prototypes for illustrating some considerations in pharmacist-generated dosage regimens.
    American journal of hospital pharmacy, 1974, Volume: 31, Issue:1

    Topics: Body Weight; Chlorpromazine; Diazepam; Dose-Response Relationship, Drug; Drug Evaluation; Half-Life; Humans; Kinetics; Lithium; Mathematics; Mental Disorders; Methods; Nortriptyline; Pharmaceutical Preparations; Time Factors

1974
Comparison of tricyclic antidepressants in rabbits: antinociception and potentiation of the noradrenaline pressor responses.
    Psychopharmacologia, 1974, Feb-27, Volume: 35, Issue:3

    Topics: Amitriptyline; Analgesics; Animals; Antidepressive Agents; Aorta; Blood Pressure; Chlorpromazine; Desipramine; Dibenzazepines; Dose-Response Relationship, Drug; Doxepin; Drug Synergism; Imipramine; In Vitro Techniques; Iprindole; Lithium; Morphine; Norepinephrine; Nortriptyline; Opipramol; Rabbits; Succinimides; Time Factors

1974
Drug interaction: inhibitory effect of neuroleptics on metabolism of tricyclic antidepressants in man.
    British medical journal, 1972, Feb-19, Volume: 1, Issue:5798

    Topics: Adult; Carbon Isotopes; Chlorpromazine; Drug Interactions; Ethanol; Female; Haloperidol; Humans; Imipramine; Male; Middle Aged; Nortriptyline; Perphenazine; Piperazines; Tranquilizing Agents

1972
Metabolism of propranolol by rat liver microsomes and its inhibition by phenothiazine and tricyclic antidepressant drugs.
    Biochemical pharmacology, 1971, Volume: 20, Issue:7

    Topics: Amitriptyline; Animals; Antidepressive Agents; Chlorpromazine; Desipramine; Imipramine; Kinetics; Liver; Male; Metabolism; Microsomes, Liver; NAD; NADP; Nitrogen; Nortriptyline; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Propranolol; Rats; Subcellular Fractions; Trifluoperazine; Triflupromazine

1971
Pharmacotherapy in the premenstrual tension.
    Activitas nervosa superior, 1971, Volume: 13, Issue:3

    Topics: Adolescent; Adult; Bipolar Disorder; Chlorpromazine; Depression; Female; Humans; Imipramine; Neurotic Disorders; Nortriptyline; Premenstrual Syndrome; Social Adjustment

1971
Effect of some drugs on the uptake of monoamines and their precursors in the mouse Paneth cells.
    Acta physiologica Scandinavica, 1971, Volume: 82, Issue:1

    Topics: 5-Hydroxytryptophan; Amines; Amitriptyline; Amphetamine; Animals; Binding Sites; Catecholamines; Chlorpromazine; Cocaine; Colon; Cytoplasmic Granules; Decarboxylation; Dihydroxyphenylalanine; Dopamine; Duodenum; Female; Guanethidine; Ileum; Imipramine; Jejunum; Male; Methyltyrosines; Mice; Microscopy, Fluorescence; Nortriptyline; Pargyline; Peptide Biosynthesis; Promazine; Reserpine; Serotonin; Tyrosine

1971
Studies of the influence of some psychotropic substances on the grooming behaviour of white mice.
    Psychopharmacologia, 1969, Volume: 14, Issue:1

    Topics: Amitriptyline; Animals; Aspirin; Charcoal; Chlordiazepoxide; Chlorpromazine; Desipramine; Dextroamphetamine; Female; Grooming; Haloperidol; Imipramine; Iproniazid; Metronidazole; Mice; Nortriptyline; Psychopharmacology

1969
[A possible mechanism of disaggregation of ADP-induced aggregates by imipramin and structurally related compouds].
    Thrombosis et diathesis haemorrhagica, 1969, Nov-15, Volume: 22, Issue:2

    Topics: Adenine Nucleotides; Amitriptyline; Blood Platelets; Chlorpromazine; Desipramine; Diphenhydramine; Humans; Imipramine; Nortriptyline; Optical Rotatory Dispersion; Platelet Adhesiveness; Promazine; Promethazine

1969
[Current problems of endogenous depression].
    Activitas nervosa superior, 1970, Jan-12, Volume: 12, Issue:1

    Topics: Amitriptyline; Antidepressive Agents; Chlorpromazine; Convulsive Therapy; Depression; Desipramine; Fluphenazine; Humans; Imipramine; Methotrimeprazine; Nortriptyline; Perphenazine; Thioridazine

1970
Studies on interactions involving antidepressive and other drugs with tetrabenazine and noradnamine on locomotor activity in mice, including details of the experimental design and statistical analysis.
    Psychopharmacologia, 1970, Volume: 18, Issue:3

    Topics: Amitriptyline; Analysis of Variance; Animals; Atropine; Bretylium Compounds; Chlorpromazine; Cycloheptanes; Depression, Chemical; Dextroamphetamine; Dibenzocycloheptenes; Drug Antagonism; Ketones; Male; Mice; Motor Activity; Nialamide; Nortriptyline; Phentolamine; Tetrabenazine

1970
[Pharmacological studies of a new antidepressant nortriptyline (Noritren)].
    Igaku kenkyu. Acta medica, 1970, Volume: 40, Issue:3

    Topics: Amitriptyline; Animals; Behavior, Animal; Body Temperature; Brain Chemistry; Cats; Chlorpromazine; Conditioning, Classical; Electroencephalography; Haloperidol; Imipramine; Mice; Norepinephrine; Nortriptyline; Perphenazine; Rats; Reserpine; Serotonin; Sleep

1970
[Tests on the analgetic effect of dextropropoxyphene combined with psychotropic drugs in the mouse].
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:7

    Topics: Amitriptyline; Analgesia; Analgesics; Animals; Antidepressive Agents; Chlorpromazine; Chlorprothixene; Clopenthixol; Dextropropoxyphene; Drug Synergism; Methods; Mice; Nortriptyline; Reflex; Stimulation, Chemical; Tranquilizing Agents

1970
Mass fragmentography and elemental analysis by means of a new and combined multiple ion detector--peak matcher device. Developments of new techniques in gas chromatography-mass spectrometry.
    Acta pharmaceutica Suecica, 1971, Volume: 8, Issue:3

    Topics: Acetylcholine; Animals; Brain Chemistry; Chlorpromazine; Chromatography, Gas; Humans; Methods; Microchemistry; Nortriptyline; Rats; Spectrum Analysis

1971
[Therapy of polyneuritides].
    Deutsche medizinische Wochenschrift (1946), 1971, Sep-03, Volume: 96, Issue:36

    Topics: Butyrophenones; Chlorpromazine; Glucocorticoids; Humans; Hypoxia; Imipramine; Methotrimeprazine; Nortriptyline; Pain; Polyneuropathies; Tranquilizing Agents; Vitamin B Complex

1971
The interaction of drugs with the conjugation of tetrahydrocortisone and a method for the measurement of the formation of its glucuronide, in vitro.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 178, Issue:3

    Topics: Amphetamine; Animals; Biotransformation; Chlorpromazine; Depression, Chemical; Drug Antagonism; Drug Synergism; Glucuronates; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Nortriptyline; Pregnanes; Proadifen; Rats; Stimulation, Chemical; Surface-Active Agents; Transferases; Tritium; Uracil Nucleotides

1971
The use of psychoactive drugs in the outpatient treatment of psychiatric disorders of children.
    The American journal of psychiatry, 1968, Volume: 124, Issue:10

    Topics: Adolescent; Amitriptyline; Child; Child Behavior Disorders; Child, Preschool; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Female; Humans; Male; Nortriptyline; Outpatient Clinics, Hospital; Parent-Child Relations; Phenothiazines; Physician-Patient Relations; Psychopharmacology; Psychotherapy

1968
Toxicity of depressant and antidepressant drugs in hyperthyroid mice.
    British medical journal, 1968, Apr-27, Volume: 2, Issue:5599

    Topics: Animals; Antidepressive Agents; Chlordiazepoxide; Chlorpromazine; Female; Hyperthyroidism; Imipramine; Meprobamate; Mice; Nortriptyline; Oxygen Consumption; Perphenazine; Phenothiazines; Reserpine; Sympathomimetics; Tranquilizing Agents

1968
Studies of the influence of some psychotropic substances on the grooming behaviour of white mice.
    British journal of pharmacology, 1968, Volume: 34, Issue:1

    Topics: Amitriptyline; Animals; Aspirin; Charcoal; Chlordiazepoxide; Chlorpromazine; Desipramine; Dextroamphetamine; Grooming; Haloperidol; Imipramine; Iproniazid; Metronidazole; Mice; Nortriptyline; Sodium Chloride; Solvents; Tranquilizing Agents

1968
Potentiation of 5-hydroxytryptamine release from platelets by desmethylation of chlorpromazine and related agents.
    Acta pharmacologica et toxicologica, 1968, Volume: 26, Issue:3

    Topics: Amitriptyline; Animals; Blood Platelets; Chlorpromazine; Drug Synergism; Imipramine; Methylation; Nortriptyline; Rabbits; Serotonin

1968
The effect of antidepressants and "tranquilizers" on the response of mice to ethanol.
    British journal of pharmacology, 1968, Volume: 34, Issue:2

    Topics: Accidents, Traffic; Amitriptyline; Animals; Antidepressive Agents; Chlorpromazine; Coma; Desipramine; Diazepam; Dibenzazepines; Drug Synergism; Ethanol; Humans; Imipramine; Methylphenidate; Mice; Nortriptyline; Phenelzine; Phenobarbital; Reflex; Substance-Related Disorders; Thioridazine; Tranquilizing Agents; Trifluoperazine

1968
Sensitivity and specificity of positive reinforcing areas to neurosedatives, antidepressants and stimulants.
    The Journal of pharmacology and experimental therapeutics, 1969, Volume: 166, Issue:1

    Topics: Animals; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Electric Stimulation; Electrodes; Hypothalamus; Imipramine; Male; Mesencephalon; Nortriptyline; Rats; Self Stimulation; Spinal Cord

1969
Extrinsic factors influencing responses to psychotherapeutic drugs.
    Archives of general psychiatry, 1969, Volume: 21, Issue:1

    Topics: Adult; Amitriptyline; Analysis of Variance; Black or African American; Chlorpromazine; Depression; Diazepam; Hospitalization; Humans; Nortriptyline; Perphenazine; Phenothiazines; Prognosis; Psychiatric Status Rating Scales; Schizophrenia; Socioeconomic Factors; Sulfonamides

1969
[Research on the mechanisms of the protective activity against gastric ulcer of psychoactive drugs: effects of nortriptyline, imipramine and chlorpromazine on gastric secretion].
    Bollettino della Societa italiana di biologia sperimentale, 1965, Sep-15, Volume: 41, Issue:17

    Topics: Animals; Atropine; Chlorpromazine; Gastric Juice; Imipramine; Nortriptyline; Rats; Stomach Ulcer

1965
Nortriptyline HCl as a tranquilizer for disturbed mentally retarded patients: a controlled study.
    The American journal of the medical sciences, 1966, Volume: 251, Issue:4

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Child; Child, Preschool; Chlorpromazine; Female; Humans; Intellectual Disability; Male; Mental Disorders; Middle Aged; Nortriptyline; Pentobarbital

1966
Effect of electroshock and antidepressant drugs on cerebrovascular permeability to cocaine in the rat.
    The Journal of nervous and mental disease, 1966, Volume: 142, Issue:4

    Topics: Amitriptyline; Animals; Antidepressive Agents; Blood-Brain Barrier; Chlorpromazine; Cocaine; Electric Stimulation; Electroshock; Female; Imipramine; Injections, Intravenous; Nortriptyline; Rats

1966
Effect of neuroleptics and tricyclic antidepressants upon d-amphetamine discrimination.
    Pharmacology, biochemistry, and behavior, 1980, Volume: 12, Issue:1

    Topics: Animals; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Chlorpromazine; Clozapine; Desipramine; Dextroamphetamine; Discrimination, Psychological; Dose-Response Relationship, Drug; Fluphenazine; Haloperidol; Imipramine; Male; Nortriptyline; Promethazine; Rats; Sodium Chloride; Thioridazine; Trifluoperazine

1980
Acute extrapyramidal side effects: serum levels of neuroleptics and anticholinergics.
    Psychopharmacology, 1981, Volume: 75, Issue:1

    Topics: Acute Disease; Animals; Antipsychotic Agents; Basal Ganglia Diseases; Bipolar Disorder; Chlorpromazine; Humans; Nortriptyline; Parasympatholytics; Radioligand Assay; Rats; Receptors, Muscarinic; Schizophrenia

1981
Therapeutic drug monitoring of psychotropic drugs in children.
    Pediatric pharmacology (New York, N.Y.), 1983, Volume: 3, Issue:3-4

    Topics: Adolescent; Adult; Age Factors; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Child; Child, Preschool; Chlorpromazine; Clomipramine; Dose-Response Relationship, Drug; Half-Life; Haloperidol; Humans; Imipramine; Kinetics; Mental Disorders; Nortriptyline

1983
Immunoassay reagents for psychoactive drugs. I. The method for the development of antibodies specific to amitriptyline and nortriptyline.
    Journal of immunological methods, 1993, Jun-04, Volume: 162, Issue:1

    Topics: Amitriptyline; Animals; Antibodies; Antibody Specificity; Chlorpromazine; Cross Reactions; Fluorescence Polarization; Immunologic Techniques; Indicators and Reagents; Models, Molecular; Nortriptyline; Rabbits; Sensitivity and Specificity

1993
ATTEMPT TO DIFFERENTIATE THYMOLEPTICS AND NEUROLEPTICS BY MEANS OF THEIR INFLUENCE ON THE EFFECTS OF RESERPINE.
    International journal of neuropharmacology, 1964, Volume: 3

    Topics: Amitriptyline; Antidepressive Agents; Antipsychotic Agents; Behavior, Animal; Body Temperature; Chlorpromazine; Chlorprothixene; Desipramine; Eyelids; Imipramine; Mice; Nortriptyline; Peptic Ulcer; Pharmacology; Rats; Research; Reserpine; Toxicology; Tranquilizing Agents

1964