chlorpromazine and norchlorpromazine

chlorpromazine has been researched along with norchlorpromazine in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19909 (60.00)18.7374
1990's4 (26.67)18.2507
2000's0 (0.00)29.6817
2010's1 (6.67)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Chan, C; Croft, SL; Douglas, KT; Fairlamb, AH; Garforth, J; Jaouhari, R; McKie, JH; Rock, PJ; Speers, P; Yardley, V; Yin, H1
Pajeva, I; Wiese, M1
Chibale, K; Kigondu, EM; Warner, DF; Wasuna, A1
Chetty, M; Miller, R1
Klee, CB; Newton, DL1
Della Corte, L; Giovannini, MG; Ninci, R; Sgaragli, G1
Young, RC1
Borowitz, JL; Hadley, R; Stebbins, G1
Andreoli, V; Borghesi, R; Della Corte, L; Moneti, G; Nardini, M; Ninci, R; Sgaragli, GP; Valoti, M1
Alfredsson, G; Bjerkenstedt, L; Edman, G; Härnryd, C; Oxenstierna, G; Sedvall, G; Wiesel, FA1
Battistini, N; Borghesi, R; Della Corte, L; Nardini, M; Ninci, R; Sgaragli, GP1
Della Corte, L; Franco, C; Giovannini, MG; Nardini, M; Ninci, R; Sgaragli, GP1
Alfredsson, G; Wode-Helgodt, B1
Minami, H; Miyahara, A; Nakahara, T; Nakane, Y1
Fu, T; Guo, Y; Huang, S; Wang, X; Yao, B; Zhang, Y1

Reviews

1 review(s) available for chlorpromazine and norchlorpromazine

ArticleYear
Pharmacologically active metabolites, combination screening and target identification-driven drug repositioning in antituberculosis drug discovery.
    Bioorganic & medicinal chemistry, 2014, Aug-15, Volume: 22, Issue:16

    Topics: Animals; Anti-Bacterial Agents; Antitubercular Agents; Drug Discovery; Fusidic Acid; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Tuberculosis

2014

Trials

2 trial(s) available for chlorpromazine and norchlorpromazine

ArticleYear
Relationships between drug concentrations in serum and CSF, clinical effects and monoaminergic variables in schizophrenic patients treated with sulpiride or chlorpromazine.
    Acta psychiatrica Scandinavica. Supplementum, 1984, Volume: 311

    Topics: Adolescent; Adult; Chlorpromazine; Clinical Trials as Topic; Double-Blind Method; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Patient Compliance; Prolactin; Schizophrenia; Sulpiride

1984
Concentrations of chlorpromazine and two of its active metabolites in plasma and cerebrospinal fluid of psychotic patients treated with fixed drug doses.
    Psychopharmacology, 1981, Volume: 73, Issue:1

    Topics: Adult; Aging; Chlorpromazine; Female; Humans; Male; Middle Aged; Psychotic Disorders; Sex Factors; Time Factors

1981

Other Studies

12 other study(ies) available for chlorpromazine and norchlorpromazine

ArticleYear
Phenothiazine inhibitors of trypanothione reductase as potential antitrypanosomal and antileishmanial drugs.
    Journal of medicinal chemistry, 1998, Jan-15, Volume: 41, Issue:2

    Topics: Animals; Antiprotozoal Agents; Binding Sites; Crithidia fasciculata; Enzyme Inhibitors; Glutathione Disulfide; Glutathione Reductase; Kinetics; Leishmania donovani; Models, Chemical; NADH, NADPH Oxidoreductases; NADP; Phenothiazines; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma cruzi

1998
Molecular modeling of phenothiazines and related drugs as multidrug resistance modifiers: a comparative molecular field analysis study.
    Journal of medicinal chemistry, 1998, May-21, Volume: 41, Issue:11

    Topics: Antineoplastic Agents; Cell Survival; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Molecular Conformation; Phenothiazines; Thioxanthenes; Tumor Cells, Cultured

1998
Effect of storage on the plasma concentration of chlorpromazine and six of its metabolites.
    Therapeutic drug monitoring, 1991, Volume: 13, Issue:4

    Topics: Chlorpromazine; Chromatography, High Pressure Liquid; Drug Stability; Drug Storage; Humans; Schizophrenia

1991
Phenothiazine-binding and attachment sites of CAPP1-calmodulin.
    Biochemistry, 1989, May-02, Volume: 28, Issue:9

    Topics: Animals; Antipsychotic Agents; Calcium; Calmodulin; Chlorpromazine; Male; Peptide Fragments; Photolysis; Sheep; Spectrophotometry, Ultraviolet; Testis; Trypsin

1989
Isothermal gas chromatographic determination of nanogram amounts of chlorimipramine, chlorpromazine and their N-desmethyl metabolites in plasma using nitrogen-selective detection.
    Journal of chromatography, 1986, Sep-05, Volume: 381, Issue:2

    Topics: Chlorpromazine; Chromatography, Gas; Clomipramine; Desipramine; Humans; Indicators and Reagents

1986
Plasma nor1-chlorpromazine concentrations: effects of age, race, and sex.
    Therapeutic drug monitoring, 1986, Volume: 8, Issue:1

    Topics: Adult; Age Factors; Chlorpromazine; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Racial Groups; Sex Factors

1986
Effects of calcium and verapamil on normal and tumor murine leukocytes.
    Research communications in chemical pathology and pharmacology, 1985, Volume: 48, Issue:2

    Topics: Animals; Calcium; Chlorpromazine; Ethanol; Leukemia P388; Leukemia, Experimental; Leukocytes; Mice; Verapamil

1985
[Dehalogenation and N-dealkylation of chlorpromazine in patients undergoing chronic treatment].
    Bollettino della Societa italiana di biologia sperimentale, 1985, Aug-30, Volume: 61, Issue:8

    Topics: Adult; Chlorpromazine; Dealkylation; Female; Humans; Male; Middle Aged; Promazine; Psychotic Disorders

1985
[N-dealkylation of chlorimipramine and chlorpromazine in patients undergoing chronic treatment with both drugs: preliminary results].
    Bollettino della Societa italiana di biologia sperimentale, 1984, Sep-30, Volume: 60, Issue:9

    Topics: Chlorpromazine; Clomipramine; Depression; Dissociative Disorders; Humans; Imipramine

1984
[A microanalytical gas liquid chromatography method with a nitrogen-phosphorus detector in the assay of various psychotropic drugs of tricyclic structure and of their N-demethylated metabolites].
    Bollettino della Societa italiana di biologia sperimentale, 1984, Sep-30, Volume: 60, Issue:9

    Topics: Chlorpromazine; Chromatography, Gas; Clomipramine; Humans; Imipramine; Microchemistry; Nitrogen; Phosphorus

1984
Prediction of drug responses in schizophrenia: a method using a test dose of chlorpromazine.
    Psychiatry and clinical neurosciences, 1997, Volume: 51, Issue:4

    Topics: Adult; Algorithms; Antipsychotic Agents; Chlorpromazine; Dose-Response Relationship, Drug; Female; Haloperidol; Humans; Male; Middle Aged; Pilot Projects; Prognosis; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Treatment Outcome

1997
Establishment of LC-MS/MS method for quantifying chlorpromazine metabolites with application to its metabolism in liver and placenta microsomes.
    Journal of pharmaceutical and biomedical analysis, 2023, Sep-05, Volume: 233

    Topics: Animals; Chlorpromazine; Chromatography, Liquid; Humans; Liver; Microsomes, Liver; Rats; Tandem Mass Spectrometry

2023