chlorpromazine and nomifensine

chlorpromazine has been researched along with nomifensine in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19908 (38.10)18.7374
1990's0 (0.00)18.2507
2000's3 (14.29)29.6817
2010's10 (47.62)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Bøgesø, KP1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Hertting, G; Jackisch, R; Reimann, W; Starke, K; Zumstein, A1
Tuomisto, J; Tuomisto, L1
Baeyens, JM; Bolaños, J; García Morillas, M; Mundo, A; Puche, E1
Compton, DR; Johnson, KM1
Arbilla, S; Baud, P; Langer, SZ1
Spaan, SJ; Westerink, BH1

Reviews

1 review(s) available for chlorpromazine and nomifensine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

20 other study(ies) available for chlorpromazine and nomifensine

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Neuroleptic activity and dopamine-uptake inhibition in 1-piperazino-3-phenylindans.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:7

    Topics: Amphetamine; Animals; Antipsychotic Agents; Biological Assay; Biological Transport; Brain; Cell Membrane; Corpus Striatum; Dopamine; Haloperidol; Indans; Indenes; Male; Mice; Norepinephrine; Piperazines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Serotonin; Structure-Activity Relationship; Synaptosomes

1983
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Species independence in brain tissue binding using brain homogenates.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Effect of extracellular dopamine on the release of dopamine in the rabbit caudate nucleus: evidence for a dopaminergic feedback inhibition.
    Naunyn-Schmiedeberg's archives of pharmacology, 1979, Volume: 306, Issue:1

    Topics: Animals; Caudate Nucleus; Chlorpromazine; Dopamine; Drug Interactions; Electric Stimulation; Feedback; Female; Haloperidol; In Vitro Techniques; Male; Nomifensine; Rabbits

1979
The accumulation of dopamine into striatal synaptosomes, and its inhibition: comparison of crude, partially purified and purified synaptosomal preparations.
    Medical biology, 1979, Volume: 57, Issue:4

    Topics: Amphetamine; Animals; Benztropine; Chlorpromazine; Corpus Striatum; Dopamine; Imipramine; Kinetics; Nomifensine; Rats; Receptors, Dopamine; Reserpine; Subcellular Fractions; Synaptosomes

1979
[Nomifensine and body temperature of the rat: interaction with reserpine, chlorpromazine and amphetamine].
    Archivos de farmacologia y toxicologia, 1979, Volume: 5, Issue:2

    Topics: Amphetamine; Animals; Body Temperature; Chlorpromazine; Drug Interactions; Isoquinolines; Male; Nomifensine; Rats; Receptors, Dopamine; Reserpine

1979
Striatal synaptosomal dopamine synthesis: evidence against direct regulation by an autoreceptor mechanism.
    European journal of pharmacology, 1985, Apr-02, Volume: 110, Issue:2

    Topics: Animals; Chlorpromazine; Corpus Striatum; Dopamine; Dopamine Antagonists; Haloperidol; Hydroxylation; In Vitro Techniques; Male; Nomifensine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sulpiride; Synaptosomes; Tyrosine 3-Monooxygenase

1985
Inhibition of the electrically evoked release of [3H]acetylcholine in rat striatal slices: an experimental model for drugs that enhance dopaminergic neurotransmission.
    Journal of neurochemistry, 1985, Volume: 44, Issue:2

    Topics: Acetylcholine; Amphetamine; Animals; Chlorpromazine; Clozapine; Cocaine; Corpus Striatum; Dopamine; Electric Stimulation; Haloperidol; Male; Nomifensine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sulpiride; Synaptic Transmission

1985
On the significance of endogenous 3-methoxytyramine for the effects of centrally acting drugs on dopamine release in the rat brain.
    Journal of neurochemistry, 1982, Volume: 38, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; 4-Butyrolactone; Animals; Apomorphine; Benztropine; Brain; Chlorpromazine; Dextroamphetamine; Dopamine; Female; Haloperidol; Homovanillic Acid; Kinetics; Morphine; Nomifensine; Oxotremorine; Rats; Rats, Inbred Strains; Reserpine

1982