chlorpromazine and midazolam

chlorpromazine has been researched along with midazolam in 43 studies

Research

Studies (43)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (4.65)	18.7374
1990's	6 (13.95)	18.2507
2000's	22 (51.16)	29.6817
2010's	11 (25.58)	24.3611
2020's	2 (4.65)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	1
Evans, CA; Jolivette, LJ; Nagilla, R; Ward, KW	1
Abraham, MH; Acree, WE; Ibrahim, A	1
Bergström, F; Giordanetto, F; Rehngren, M; Tunek, A; Wan, H	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z	1
Faller, B; Trunzer, M; Zimmerlin, A	1
Ahman, M; Holmén, AG; Wan, H	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Dalvie, D; Loi, CM; Smith, DA	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Dodge, WF; Snodgrass, WR	1
Evans, S; Johanson, C	1
Elderbrook, MK; Hollman, GA; VanDenLangenberg, B	1
Bates, BA; Fleisher, GR; Schutzman, SA	1
Green, CJ	1
Balster, RL; Evans, EB	1
Berns, SD; Boenning, DA; Hart, LS; Houck, CS	1
Croffie, JM; Ellett, ML; Fitzgerald, JF; Lou, Q	1
Auden, SM; Goldsmith, LJ; Sobczyk, WL; Solinger, RE	1
Abuhandan, M; Caksen, H; Celebi, V; Cesur, Y; Sar, S; Uner, A	1
Alp, H; Altinkaynak, S; Güler, I; Orbak, Z	1
Cassu, RN; Castro, GB; Lopes, MD; Luna, SP; Silva Júnior, JR; Teixeira Neto, FJ	1
Baguley, IJ; Cameron, ID; Green, AM; Gurka, JA; Marosszeky, JE; Slewa-Younan, S	1
Bhoopathy, S; Karnes, HT; Unger, SE; Xin, B	1
Boohene, J; Bruera, E; Calderon, B; Curry Iii, E; Elsayem, A; Hung, F; Munsell, MF	1
Graudins, A; Green, D; Morris, E	1
Chin, K; Doi, H; Handa, T; Ikeda, T; Mishima, M; Murata, M; Nakahata, T; Oga, T; Sakata, R; Takahashi, K; Tsuboi, T; Watanabe, K	1
Chen, Y; Subramanian, R; Zhu, X	1
Clark, RD; Fraczkiewicz, R; Waldman, M	1
Iba, Y; Kimura, T; Murai, H; Suzuki, H; Tanji, H	1
Hatachi, T; Inata, Y; Kyogoku, M; Sofue, T; Takeuchi, M	1

Reviews

2 review(s) available for chlorpromazine and midazolam

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Lytic/"DPT" cocktail: time for rational and safe alternatives. Pediatric clinics of North America, 1989, Volume: 36, Issue:5 Topics: Child; Child, Preschool; Chlorpromazine; Diazepam; Drug Combinations; Humans; Infant; Meperidine; Midazolam; Morphine; Preanesthetic Medication; Promethazine	1989

Trials

3 trial(s) available for chlorpromazine and midazolam

Article	Year
A comparison of intranasal sufentanil and midazolam to intramuscular meperidine, promethazine, and chlorpromazine for conscious sedation in children. Annals of emergency medicine, 1994, Volume: 24, Issue:4 Topics: Administration, Intranasal; Anxiety; Child Behavior; Child, Preschool; Chlorpromazine; Conscious Sedation; Drug Combinations; Female; Humans; Infant; Injections, Intramuscular; Male; Meperidine; Midazolam; Pain Measurement; Promethazine; Single-Blind Method; Sufentanil; Sutures; Wounds, Penetrating	1994
The value of end-tidal CO2 monitoring when comparing three methods of conscious sedation for children undergoing painful procedures in the emergency department. Pediatric emergency care, 1997, Volume: 13, Issue:3 Topics: Capnography; Carbon Dioxide; Child; Chlorpromazine; Conscious Sedation; Drug Combinations; Emergency Service, Hospital; Female; Fentanyl; Humans; Hypnotics and Sedatives; Infant; Male; Meperidine; Midazolam; Narcotics; Pain; Promethazine; Respiration Disorders	1997
Oral ketamine/midazolam is superior to intramuscular meperidine, promethazine, and chlorpromazine for pediatric cardiac catheterization. Anesthesia and analgesia, 2000, Volume: 90, Issue:2 Topics: Adjuvants, Anesthesia; Administration, Oral; Cardiac Catheterization; Child; Child, Preschool; Chlorpromazine; Double-Blind Method; Hemodynamics; Humans; Hypnotics and Sedatives; Infant; Injections, Intramuscular; Ketamine; Meperidine; Midazolam; Promethazine	2000

Other Studies

38 other study(ies) available for chlorpromazine and midazolam

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Rational use of in vitro P-glycoprotein assays in drug discovery. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2 Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera	2001
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Extrapolation of preclinical pharmacokinetics and molecular feature analysis of "discovery-like" molecules to predict human pharmacokinetics. Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:7 Topics: Animals; Biometry; Dogs; Drug Evaluation, Preclinical; Haloperidol; Haplorhini; Humans; Injections, Intravenous; Liver; Liver Circulation; Metabolic Clearance Rate; Mifepristone; Molecular Structure; Molecular Weight; Rats; Reproducibility of Results	2006
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs. European journal of medicinal chemistry, 2008, Volume: 43, Issue:3 Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization	2008
High-throughput screening of drug-brain tissue binding and in silico prediction for assessment of central nervous system drug delivery. Journal of medicinal chemistry, 2007, Sep-20, Volume: 50, Issue:19 Topics: Animals; Brain; Central Nervous System Agents; Dialysis; Hydrophobic and Hydrophilic Interactions; In Vitro Techniques; Mice; Models, Statistical; Protein Binding; Quantitative Structure-Activity Relationship; Rats	2007
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human. European journal of medicinal chemistry, 2009, Volume: 44, Issue:4 Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software	2009
Metabolic soft spot identification and compound optimization in early discovery phases using MetaSite and LC-MS/MS validation. Journal of medicinal chemistry, 2009, Jan-22, Volume: 52, Issue:2 Topics: Chromatography, Liquid; Drug Design; Humans; Likelihood Functions; Microsomes, Liver; Pharmacokinetics; Tandem Mass Spectrometry	2009
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs. Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6 Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2 Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Which metabolites circulate? Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:5 Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations	2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
The discriminative stimulus properties of midazolam in pigeons. NIDA research monograph, 1988, Volume: 81 Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Buspirone; Chlorpromazine; Columbidae; Discrimination Learning; Mazindol; Midazolam; Morphine; Pyridazines	1988
Results of a pediatric sedation program on head MRI scan success rates and procedure duration times. Clinical pediatrics, 1995, Volume: 34, Issue:6 Topics: Ambulatory Care; Child; Chloral Hydrate; Chlorpromazine; Conscious Sedation; Contrast Media; Female; Head; Humans; Magnetic Resonance Imaging; Male; Meperidine; Midazolam; Pentobarbital; Program Evaluation; Promethazine; Retrospective Studies; Safety; Time Factors	1995
Options for sedating children. The Western journal of medicine, 1993, Volume: 159, Issue:5 Topics: Barbiturates; Child; Chloral Hydrate; Chlorpromazine; Conscious Sedation; Drug Combinations; Emergency Service, Hospital; Humans; Meperidine; Midazolam; Promethazine	1993
Inhaled 1,1,1-trichloroethane-produced physical dependence in mice: effects of drugs and vapors on withdrawal. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:2 Topics: Administration, Inhalation; Animals; Chlorpromazine; Ethanol; Male; Mice; Midazolam; Pentobarbital; Phenytoin; Substance Withdrawal Syndrome; Substance-Related Disorders; Toluene; Trichloroethanes; Volatilization	1993
A comparison of the effect of three sedatives on esophageal sphincters in cats. Digestive diseases (Basel, Switzerland), 1999, Volume: 17, Issue:2 Topics: Analgesics, Opioid; Animals; Antipsychotic Agents; Cats; Central Nervous System Agents; Chloral Hydrate; Chlorpromazine; Cross-Over Studies; Drug Combinations; Esophageal Diseases; Esophagogastric Junction; Evaluation Studies as Topic; Hypnotics and Sedatives; Meperidine; Midazolam; Promethazine; Random Allocation	1999
Comparison of lytic cocktail, chloral hydrate and midazolam for pediatric sedation. Journal of tropical pediatrics, 2001, Volume: 47, Issue:5 Topics: Adjuvants, Anesthesia; Child; Chloral Hydrate; Chlorpromazine; Conscious Sedation; Dopamine Antagonists; Drug Combinations; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; Meperidine; Midazolam; Pheniramine	2001
Efficacy and safety of rectal thiopental, intramuscular cocktail and rectal midazolam for sedation in children undergoing neuroimaging. Pediatrics international : official journal of the Japan Pediatric Society, 2002, Volume: 44, Issue:6 Topics: Administration, Rectal; Analysis of Variance; Anesthesia; Anesthetics, Combined; Brain; Child; Child, Preschool; Chlorpromazine; Female; Humans; Hypnotics and Sedatives; Infant; Injections, Intramuscular; Magnetic Resonance Imaging; Male; Meperidine; Midazolam; Pheniramine; Thiopental; Tomography, X-Ray Computed; Turkey	2002
Effects of four anaesthetic protocols on the neurological and cardiorespiratory variables of puppies born by caesarean section. The Veterinary record, 2004, Mar-27, Volume: 154, Issue:13 Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Combined; Animals; Bupivacaine; Cesarean Section; Chlorpromazine; Dogs; Enflurane; Epinephrine; Female; Heart Rate; Ketamine; Lidocaine; Midazolam; Pregnancy; Propofol; Random Allocation; Reflex; Respiration; Thiopental	2004
Pharmacological management of Dysautonomia following traumatic brain injury. Brain injury, 2004, Volume: 18, Issue:5 Topics: Adult; Autonomic Nervous System Diseases; Brain Injuries; Case-Control Studies; Chlorpromazine; Female; Humans; Male; Midazolam; Morphine; Neurotransmitter Agents; Retrospective Studies; Time Factors	2004
A novel incubation direct injection LC/MS/MS technique for in vitro drug metabolism screening studies involving the CYP 2D6 and the CYP 3A4 isozymes. Journal of pharmaceutical and biomedical analysis, 2005, Apr-01, Volume: 37, Issue:4 Topics: Algorithms; Animals; Antitussive Agents; Chlorpromazine; Chromatography, Liquid; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dextromethorphan; Enzyme Inhibitors; Half-Life; Humans; Hypnotics and Sedatives; In Vitro Techniques; Indicators and Reagents; Isoenzymes; Microsomes, Liver; Midazolam; Pharmaceutical Preparations; Primaquine; Quinidine; Rats; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization	2005
Use of palliative sedation for intractable symptoms in the palliative care unit of a comprehensive cancer center. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2009, Volume: 17, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Cancer Care Facilities; Chlorpromazine; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Midazolam; Middle Aged; Neoplasms; Palliative Care; Practice Patterns, Physicians'; Retrospective Studies; Young Adult	2009
Neuroleptic malignant syndrome developing after acute overdose with olanzapine and chlorpromazine. Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2009, Volume: 5, Issue:1 Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bromocriptine; Chlorpromazine; Citalopram; Combined Modality Therapy; Dopamine Agonists; Drug Overdose; Female; Humans; Hypnotics and Sedatives; Hypothermia, Induced; Infusions, Intravenous; Midazolam; Neuroleptic Malignant Syndrome; Olanzapine; Respiration, Artificial; Treatment Outcome	2009
Avoidance of reintubation by using sedation during noninvasive positive pressure ventilation in a 3-month-old infant with postoperative respiratory failure. Internal medicine (Tokyo, Japan), 2010, Volume: 49, Issue:12 Topics: Chlorpromazine; Deep Sedation; Humans; Infant; Intubation, Intratracheal; Male; Midazolam; Positive-Pressure Respiration; Postoperative Complications; Respiratory Insufficiency	2010
Comparison of information-dependent acquisition, SWATH, and MS(All) techniques in metabolite identification study employing ultrahigh-performance liquid chromatography-quadrupole time-of-flight mass spectrometry. Analytical chemistry, 2014, Jan-21, Volume: 86, Issue:2 Topics: Algorithms; Animals; Biotransformation; Chlorpromazine; Chromatography, High Pressure Liquid; Ethanolamines; Microsomes, Liver; Midazolam; Oxidation-Reduction; Quinidine; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	2014
Tales from the war on error: the art and science of curating QSAR data. Journal of computer-aided molecular design, 2015, Volume: 29, Issue:9 Topics: Chlorpromazine; Cytochrome P-450 Enzyme System; Data Accuracy; Data Curation; Isomerism; Methylergonovine; Midazolam; Molecular Structure; Quantitative Structure-Activity Relationship; Terminology as Topic; Thermodynamics; Transition Temperature	2015
A simple method using anesthetics to test effects of sleep-inducing substances in mice. Journal of pharmacological sciences, 2020, Volume: 142, Issue:2 Topics: Anesthesia; Anesthetics; Animals; Azepines; Butorphanol; Chlorpromazine; Drug Combinations; Imidazoles; Indenes; Isoflurane; Male; Medetomidine; Mice; Mice, Inbred ICR; Midazolam; Orexin Receptor Antagonists; Sleep Aids, Pharmaceutical; Triazoles	2020
Prone positioning without neuromuscular blockade during extracorporeal membrane oxygenation in children. Pediatrics international : official journal of the Japan Pediatric Society, 2020, Volume: 62, Issue:5 Topics: Adolescent; Child; Child, Preschool; Chlorpromazine; Dexmedetomidine; Extracorporeal Membrane Oxygenation; Fentanyl; Humans; Hypnotics and Sedatives; Infant; Japan; Midazolam; Morphine; Neuromuscular Blockade; Prone Position; Respiratory Insufficiency; Retrospective Studies	2020