chlorpromazine and metronidazole

chlorpromazine has been researched along with metronidazole in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19906 (23.08)18.7374
1990's2 (7.69)18.2507
2000's7 (26.92)29.6817
2010's11 (42.31)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Uma Devi, P; Veena, K1
Hegenscheid, B; Presber, HW1
Johri, MB; Saxena, PN; Singhal, KC1
Farkas, G1
Chaftez, ME1
Rohte, O2
Eisenberg, NH; Hauser, GJ; Reisner, SH; Stahl, B1
Fathinia, M; Joo, SW; Khataee, AR1

Reviews

3 review(s) available for chlorpromazine and metronidazole

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Drugs in the treatment of alcoholism.
    The Medical clinics of North America, 1967, Volume: 51, Issue:5

    Topics: Alcohol Deterrents; Alcoholic Intoxication; Alcoholism; Amitriptyline; Antidepressive Agents; Chlordiazepoxide; Chlorpromazine; Disulfiram; Humans; Imipramine; Metronidazole; Tranquilizing Agents

1967
Maternal medications and breast-feeding.
    Developmental pharmacology and therapeutics, 1983, Volume: 6, Issue:5

    Topics: Anti-Anxiety Agents; Aspirin; Benzodiazepines; Breast Feeding; Chlorpromazine; Contraceptives, Oral; Ergot Alkaloids; Female; Humans; Metronidazole; Milk, Human; Pharmaceutical Preparations; Pregnancy; Thiouracil

1983

Other Studies

23 other study(ies) available for chlorpromazine and metronidazole

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
MICE models: superior to the HERG model in predicting Torsade de Pointes.
    Scientific reports, 2013, Volume: 3

    Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the toxic and radiosensitizing effects of five therapeutic drugs on the mouse jejunum.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1990, Volume: 166, Issue:8

    Topics: Animals; Bleomycin; Chlorpromazine; Cisplatin; Cobalt Radioisotopes; Jejunum; Metronidazole; Mice; Misonidazole; Radiation Dosage; Radiation-Sensitizing Agents; Whole-Body Irradiation

1990
[Antiprotozoal effects of benzodiazepine derivatives].
    Angewandte Parasitologie, 1990, Volume: 31, Issue:4

    Topics: Animals; Benzodiazepines; Chlorpromazine; Clomipramine; Crithidia; Desipramine; Eukaryota; Imipramine; Leishmania mexicana; Metronidazole; Trichomonas vaginalis; Trypanosoma cruzi

1990
Studies on the use of Setaria cervi for in vitro antifilarial screening.
    Japanese journal of pharmacology, 1973, Volume: 23, Issue:6

    Topics: Animals; Anthelmintics; Arsenicals; Chlorpromazine; Coal Tar; Diethylcarbamazine; Drug Evaluation, Preclinical; Filaricides; Filarioidea; Fluoresceins; Gentian Violet; Glucose; Magnesium; Mercury; Metronidazole; Penicillins; Phosphates; Piperazines; Promethazine; Streptomycin; Sulfathiazoles; Thiabendazole; Time Factors

1973
[Proceedings: Is hemorrhage in early pregnancy and its drug therapy an increased risk of teratogenesis?].
    Archiv fur Gynakologie, 1973, Sep-28, Volume: 214, Issue:1

    Topics: Abnormalities, Drug-Induced; Abortion, Threatened; Allyl Compounds; Aminopyrine; Chlordiazepoxide; Chlorpromazine; Estranes; Female; Humans; Hydroxysteroids; Metronidazole; Pregnancy; Pregnancy Complications, Cardiovascular; Progesterone; Progestins; Romania; Stilbenes; Uterine Hemorrhage

1973
Studies of the influence of some psychotropic substances on the grooming behaviour of white mice.
    Psychopharmacologia, 1969, Volume: 14, Issue:1

    Topics: Amitriptyline; Animals; Aspirin; Charcoal; Chlordiazepoxide; Chlorpromazine; Desipramine; Dextroamphetamine; Female; Grooming; Haloperidol; Imipramine; Iproniazid; Metronidazole; Mice; Nortriptyline; Psychopharmacology

1969
Studies of the influence of some psychotropic substances on the grooming behaviour of white mice.
    British journal of pharmacology, 1968, Volume: 34, Issue:1

    Topics: Amitriptyline; Animals; Aspirin; Charcoal; Chlordiazepoxide; Chlorpromazine; Desipramine; Dextroamphetamine; Grooming; Haloperidol; Imipramine; Iproniazid; Metronidazole; Mice; Nortriptyline; Sodium Chloride; Solvents; Tranquilizing Agents

1968
Simultaneous monitoring of photocatalysis of three pharmaceuticals by immobilized TiO2 nanoparticles: chemometric assessment, intermediates identification and ecotoxicological evaluation.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2013, Volume: 112

    Topics: Araceae; Atenolol; Catalysis; Chlorpromazine; Metronidazole; Nanoparticles; Photolysis; Titanium; Ultraviolet Rays; Water Pollutants, Chemical

2013