chlorpromazine and mercaptopurine

chlorpromazine has been researched along with mercaptopurine in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19905 (26.32)18.7374
1990's0 (0.00)18.2507
2000's4 (21.05)29.6817
2010's9 (47.37)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Aquino, TM; Araújo-Júnior, JX; da Silva-Júnior, EF; Leoncini, GO; Rodrigues, ÉES1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Brodinova, NS; Moroz, AF1
Brodinova, NS; Moroz, AF; Podboronov, VM1
Mukhtar, H; Murti, CR1
Chinea, G; Colombo, C; Graeme, ML; Piliero, SJ; Sigg, EB1
BUTLER, WT; COONS, AH1

Reviews

2 review(s) available for chlorpromazine and mercaptopurine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
The medicinal chemistry of Chikungunya virus.
    Bioorganic & medicinal chemistry, 2017, 08-15, Volume: 25, Issue:16

    Topics: Animals; Antiviral Agents; Biological Products; Chemistry, Pharmaceutical; Chikungunya Fever; Chikungunya virus; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship

2017

Other Studies

17 other study(ies) available for chlorpromazine and mercaptopurine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
[The increase of resistance of Staphylococcus and Escherichia coli to some antibiotics and their combinations with DNA-tropic substances].
    Antibiotiki, 1970, Volume: 15, Issue:9

    Topics: Acridines; Ampicillin; Anti-Bacterial Agents; Antimetabolites; Azaguanine; Chlorpromazine; Escherichia coli; Flavonoids; Mercaptopurine; Neomycin; Novobiocin; Penicillin Resistance; Penicillins; Phenothiazines; Protamines; Quinacrine; Ristocetin; Staphylococcus; Streptomycin; Vasodilator Agents

1970
[Prevention of the development of drug resistant forms of staphylococci by a combination of antibiotics with DNA-tropic compounds].
    Antibiotiki, 1971, Volume: 16, Issue:5

    Topics: Acridines; Anti-Bacterial Agents; Azaguanine; Chlorpromazine; Culture Media; Depression, Chemical; DNA, Bacterial; Flavonoids; Mercaptopurine; Mutation; Novobiocin; Penicillin Resistance; Penicillins; Phenothiazines; Quinacrine; Staphylococcus; Time Factors; Vasodilator Agents

1971
Induction of rat liver tyrosine aminotransferase by pharmacologically unrelated drugs.
    Indian journal of biochemistry, 1971, Volume: 8, Issue:2

    Topics: Animals; Azaguanine; Chloroquine; Chlorpromazine; Enzyme Induction; Liver; Mercaptopurine; Phenacetin; Rats; Tetracycline; Tyrosine Transaminase

1971
Action of anti-inflammatory agents upon blood and histopathologic changes induced by periarthritis in rats.
    Life sciences, 1966, Volume: 5, Issue:12

    Topics: Adrenal Glands; Animals; Blood Cell Count; Blood Protein Electrophoresis; Blood Sedimentation; Chlorpromazine; Fibrinogen; Indomethacin; Male; Mercaptopurine; Methotrexate; Organ Size; Oxyphenbutazone; Paramethasone; Phenylbutazone; Rats; Spleen; Streptomycin; Thymus Gland

1966
STUDIES ON ANTIBODY PRODUCTION. XII. INHIBITION OF PRIMING BY DRUGS.
    The Journal of experimental medicine, 1964, Dec-01, Volume: 120

    Topics: Animals; Antibody Formation; Antineoplastic Agents; Antiprotozoal Agents; Azaguanine; Chloramphenicol; Chlorpromazine; Colchicine; Dactinomycin; Edetic Acid; Hydrocortisone; Immunization; Mercaptopurine; Methotrexate; Mice; Pharmacology; Quinolines; Research; Thiotepa; Vaccination

1964