chlorpromazine and melatonin

chlorpromazine has been researched along with melatonin in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199013 (50.00)18.7374
1990's3 (11.54)18.2507
2000's4 (15.38)29.6817
2010's6 (23.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Arce, MP; Conde, S; del Barrio, L; Egea, J; García, AG; González-Muñoz, GC; León, R; López, B; López, MG; Martín-de-Saavedra, MD; Pérez, C; Rodríguez-Franco, MI; Romero, A; Villarroya, M1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Arce, MP; Conde, S; Egea, J; Gil, C; León, R; López, MG; Monjas, L; Pérez, C; Rodríguez-Franco, MI; Villarroya, M1
Chan, ASC; Feng, X; Hu, J; Huang, L; Li, X; Wang, Z; Yang, X1
Barnes, JL; Mee, TJ; Smith, JA2
Black, JJ; Erskine, D; Hutchison, VH1
Lynch, HJ; Ozaki, Y; Wurtman, RJ1
Kay, SR; Sandyk, R1
Durst, R; Ghinea, C; Nir, I; Robinson, S; Rosca, P; Schmidt, U; Shai, U1
Weiss, B1
Van der Hoeven, T; Woolley, DW1
Kostellow, AB; Morrill, GA1
Anton-Tay, F; Axelrod, J; Wurtman, RJ1
Axelrod, J; Wurtman, RJ1
Hart, N; Hutchison, VH1
Hirschmann, N; Nir, I1
Cremer-Bartels, G; Kaufmann, F; Küchle, HJ1
Erskine, DJ; Hutchison, VH1
García-Pergañeda, A; Guerrero, JM; Osuna, C; Romero, MP1
Adjou, KT; Auvré, F; Barret, A; Bate, C; Colombo, L; De Luigi, A; Deslys, JP; Forloni, G; Lasmézas, C; Limido, L; Rossi, G; Salès, N; Salmona, M; Suardi, S; Tagliavini, F; Williams, A1
Al-Shawi, NN; Hussain, SA; Jwaied, AH; Mahmood, DM; Sulaiman, AA1
Cabello, C; de Menezes, ML; Fernandes, JR; Rodrigues, AP; Ximenes, VF1
Ximenes, VF1

Reviews

1 review(s) available for chlorpromazine and melatonin

ArticleYear
On the regulation of adenyl cyclase activity in the rat pineal gland.
    Annals of the New York Academy of Sciences, 1971, Dec-30, Volume: 185

    Topics: Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Castration; Cerebellum; Chlorpromazine; Cyclic AMP; Darkness; Firefly Luciferin; Light; Luciferases; Melatonin; Methyltransferases; Models, Biological; Norepinephrine; Phosphoric Monoester Hydrolases; Pineal Gland; Radiation Effects; Rats; Serotonin; Sulfoxides; Trifluoperazine

1971

Other Studies

25 other study(ies) available for chlorpromazine and melatonin

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:6

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Antineoplastic Agents; Butyrylcholinesterase; Calcium; Cell Death; Cell Survival; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Okadaic Acid; Peptide Fragments; Phenothiazines; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Enzymatic and solid-phase synthesis of new donepezil-based L- and d-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer's disease and cerebral ischemia.
    European journal of medicinal chemistry, 2017, Apr-21, Volume: 130

    Topics: Alzheimer Disease; Animals; Brain Ischemia; Calcium Channel Blockers; Cholinesterase Inhibitors; Donepezil; Glutamates; Hippocampus; Humans; Indans; Neuroprotective Agents; Piperidines; Rats; Solid-Phase Synthesis Techniques

2017
Design, Synthesis, and Evaluation of Orally Bioavailable Quinoline-Indole Derivatives as Innovative Multitarget-Directed Ligands: Promotion of Cell Proliferation in the Adult Murine Hippocampus for the Treatment of Alzheimer's Disease.
    Journal of medicinal chemistry, 2018, 03-08, Volume: 61, Issue:5

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Cell Proliferation; Drug Design; Hippocampus; Humans; Indoles; Ligands; Memory Disorders; Mice; Quinolines

2018
Elevated melatonin serum concentrations in psychiatric patients treated with chlorpromazine [proceedings].
    The Journal of pharmacy and pharmacology, 1977, Volume: 29 Suppl

    Topics: Adolescent; Adult; Chlorpromazine; Humans; Male; Melatonin; Mental Disorders; Middle Aged; Stimulation, Chemical

1977
The effect of neuroleptic drugs on serum and cerebrospinal fluid melatonin concentrations in psychiatric subjects.
    The Journal of pharmacy and pharmacology, 1979, Volume: 31, Issue:4

    Topics: Adolescent; Adult; Age Factors; Aged; Antipsychotic Agents; Chlorpromazine; Female; Flupenthixol; Fluphenazine; Humans; Male; Melatonin; Mental Disorders; Middle Aged

1979
Melatonin and chlorpromazine: thermal selection in the mudpuppy, Necturus maculosus.
    Life sciences, 1979, Aug-06, Volume: 25, Issue:6

    Topics: Animals; Behavior, Animal; Body Temperature Regulation; Chlorpromazine; Circadian Rhythm; Melatonin; Temperature; Urodela

1979
Melatonin in rat pineal, plasma, and urine: 24-hour rhythmicity and effect of chlorpromazine.
    Endocrinology, 1976, Volume: 98, Issue:6

    Topics: Animals; Biological Assay; Chlorpromazine; Chromatography, Thin Layer; Circadian Rhythm; Male; Melatonin; Pineal Gland; Radioimmunoassay; Rana pipiens; Rats

1976
Abnormal EEG and calcification of the pineal gland in schizophrenia.
    The International journal of neuroscience, 1992, Volume: 62, Issue:1-2

    Topics: Adult; Aged; Calcinosis; Chlorpromazine; Electroencephalography; Female; Humans; Male; Melatonin; Middle Aged; Pineal Gland; Schizophrenia; Tomography, X-Ray Computed

1992
Serum melatonin levels in schizophrenic and schizoaffective hospitalized patients.
    Acta psychiatrica Scandinavica, 1991, Volume: 84, Issue:3

    Topics: Adult; Chlorpromazine; Circadian Rhythm; Depressive Disorder; Drug Therapy, Combination; Female; Fluphenazine; Haloperidol; Humans; Male; Melatonin; Middle Aged; Psychiatric Status Rating Scales; Psychotic Disorders; Schizophrenia; Schizophrenic Psychology

1991
Serotonin deficiency in infancy as a cause of a mental defect in experimental phenylketonuria.
    International journal of neuropsychiatry, 1965, Volume: 1, Issue:6

    Topics: 5-Hydroxytryptophan; Animals; Animals, Newborn; Chlorpromazine; Electroshock; Female; Humans; In Vitro Techniques; Intellectual Disability; Learning; Male; Melatonin; Mice; Neurosecretion; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Reserpine; Serotonin; Tryptamines; Tyrosine; Urine

1965
Tryptophan induction of the serotonin and kynurenine pathways in the early amphibian embryo.
    Nature: New biology, 1971, May-26, Volume: 231, Issue:21

    Topics: 5-Hydroxytryptophan; Animals; Anura; Carbon Isotopes; Chloramphenicol; Chlorpromazine; Chromatography, Thin Layer; Culture Techniques; Depression, Chemical; Embryo, Nonmammalian; Enzyme Induction; Ethanol; Indoles; Iproniazid; Kynurenine; Melatonin; Mixed Function Oxygenases; Protein Biosynthesis; RNA; Serotonin; Tryptophan; Tryptophan Oxygenase

1971
Inhibition of the metabolism of H3-melatonin by phenothiazines.
    The Journal of pharmacology and experimental therapeutics, 1968, Volume: 161, Issue:2

    Topics: Amphetamine; Animals; Antimetabolites; Body Temperature; Brain; Chlorpromazine; Depression, Chemical; Desipramine; Female; Imipramine; Liver; Melatonin; Phenobarbital; Phenothiazines; Promazine; Promethazine; Rats; Tritium

1968
Effect of chlorpromazine and other drugs on the disposition of circulating melatonin.
    Nature, 1966, Oct-15, Volume: 212, Issue:5059

    Topics: Animals; Brain Chemistry; Chlorpromazine; Eye; Female; Melatonin; Myocardium; Neurosecretion; Ovary; Pineal Gland; Rats; Reserpine; Serotonin; Skin; Tritium; Tryptamines

1966
Decreased thermal tolerance in Mus musculus with melatonin and chlorpromazine.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1984, Volume: 78, Issue:2

    Topics: Adaptation, Physiological; Animals; Body Temperature Regulation; Chlorpromazine; Female; Hot Temperature; Male; Melatonin; Mice; Sex Factors; Time Factors

1984
Effect of psychotrophic drugs on [14C]tryptophan metabolism in cultured rat pineal gland.
    Biochemical pharmacology, 1983, Jul-15, Volume: 32, Issue:14

    Topics: Animals; Cells, Cultured; Chlorpromazine; Desipramine; Haloperidol; Male; Melatonin; Norepinephrine; Phenothiazines; Pineal Gland; Psychotropic Drugs; Rats; Serotonin; Tryptophan

1983
[Effect of chlorpromazine on biosynthesis of melatonin in the retina].
    Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1983, Volume: 79, Issue:5

    Topics: Acetylserotonin O-Methyltransferase; Animals; Chlorpromazine; Male; Melatonin; Pineal Gland; Quail; Retina

1983
Melatonin and behavioral thermoregulation in the turtle, Terrapene carolina triunguis.
    Physiology & behavior, 1981, Volume: 26, Issue:6

    Topics: Animals; Behavior, Animal; Body Temperature Regulation; Chlorpromazine; Circadian Rhythm; Melatonin; Time Factors; Turtles

1981
Membrane-bound calmodulin in Xenopus laevis oocytes as a novel binding site for melatonin.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1998, Volume: 12, Issue:13

    Topics: Animals; Binding Sites; Binding, Competitive; Calcium; Calcium Signaling; Calmodulin; Chlorpromazine; Egg Proteins; Female; Indoles; Kinetics; Melatonin; Membrane Proteins; Oocytes; Protein Binding; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Temperature; Xenopus laevis

1998
Evaluation of quinacrine treatment for prion diseases.
    Journal of virology, 2003, Volume: 77, Issue:15

    Topics: Animals; Chlorpromazine; Cricetinae; Drug Resistance; Endopeptidase K; Humans; Melatonin; Mice; Mice, Inbred C57BL; Peptides; Prion Diseases; Prions; PrPC Proteins; PrPSc Proteins; Quinacrine; Tumor Cells, Cultured

2003
Protective effect of melatonin against chlorpromazine-induced liver disease in rats.
    Saudi medical journal, 2006, Volume: 27, Issue:10

    Topics: Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Chlorpromazine; Disease Models, Animal; Dopamine Antagonists; Female; Liver; Liver Diseases; Male; Melatonin; Oxidative Stress; Rats

2006
The co-catalytic effect of chlorpromazine on peroxidase-mediated oxidation of melatonin: enhanced production of N1-acetyl-N2-formyl-5-methoxykynuramine.
    Journal of pineal research, 2008, Volume: 44, Issue:2

    Topics: Animals; Antioxidants; Antipsychotic Agents; Chlorpromazine; Humans; Kynuramine; Melatonin; Oxidants; Oxidation-Reduction; Peroxidase; Rats; Spectrophotometry, Ultraviolet

2008
Optimized synthesis of the melatonin metabolite N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK).
    Journal of pineal research, 2008, Volume: 45, Issue:3

    Topics: Chlorpromazine; Chromatography, High Pressure Liquid; Horseradish Peroxidase; Hydrogen-Ion Concentration; Kynuramine; Melatonin; Osmolar Concentration; Oxidation-Reduction; Oxygen

2008