chlorpromazine has been researched along with maprotiline in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (12.90) | 18.7374 |
| 1990's | 3 (9.68) | 18.2507 |
| 2000's | 10 (32.26) | 29.6817 |
| 2010's | 14 (45.16) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Kottke, T; Ligneau, X; Stark, H; von Coburg, Y; Weizel, L | 1 |
| Faller, B; Trunzer, M; Zimmerlin, A | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Atzpodien, EA; Csato, M; Doessegger, L; Fischer, H; Lenz, B; Schmitt, G; Singer, T | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Berger, ML; Rebernik, P | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Lee, RL; Spencer, PS | 1 |
| Chen, PO; Endo, T; Matsuda, H; Nishimori, T; Sato, K; Shibuya, T | 1 |
| Kawasaki, H; Ueki, S; Watanabe, S | 1 |
| Hoffman, BF; Wachsmuth, R | 1 |
| Abdelmalik, OM; Airaudo, CB; Gayte-Sorbier, A; Guerri, J; Tchiakpé, L; Verdier, M | 1 |
| Graf, U; van Schaik, N | 1 |
| Airaudo, CB; Bianchi, C; Gayte-Sorbier, A; Verdier, M | 1 |
| Kanba, S; Miyaoka, H; Nakaki, T; Shintani, F; Suzuki, E | 1 |
1 review(s) available for chlorpromazine and maprotiline
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
30 other study(ies) available for chlorpromazine and maprotiline
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Potential utility of histamine H3 receptor antagonist pharmacophore in antipsychotics.
Topics: Animals; Antipsychotic Agents; Cell Line; CHO Cells; Cricetinae; Cricetulus; Histamine Antagonists; Humans; Radioligand Assay; Receptors, Histamine H3 | 2009 |
Metabolic soft spot identification and compound optimization in early discovery phases using MetaSite and LC-MS/MS validation.
Topics: Chromatography, Liquid; Drug Design; Humans; Likelihood Functions; Microsomes, Liver; Pharmacokinetics; Tandem Mass Spectrometry | 2009 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets.
Topics: Animals; Cattle; Cells, Cultured; Computer Simulation; Cornea; Drug-Related Side Effects and Adverse Reactions; Fibroblasts; Lipidoses; Lysosomal Storage Diseases; Models, Molecular; Pharmaceutical Preparations; Phospholipids; Structure-Activity Relationship; Thermodynamics | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Differential influence of 7 cations on 16 non-competitive NMDA receptor blockers.
Topics: Animals; Brain; Cations; Diamines; Dizocilpine Maleate; Dose-Response Relationship, Drug; Molecular Structure; Rats; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship | 2015 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
The effect of clomipramine and other amine-uptake inhibitors on morphine analgesia in laboratory animals.
Topics: Analgesia; Animals; Chlorpromazine; Clomipramine; Dibenzazepines; Dibenzocycloheptenes; Drug Synergism; Drug Tolerance; Male; Maprotiline; Mice; Morphine; Pentazocine; Phenyl Ethers; Proadifen; Propylamines; Quipazine; Rats | 1977 |
Pharmacological studies of drug action on CNS, with special reference to effects of maprotiline.
Topics: Action Potentials; Amitriptyline; Animals; Anthracenes; Antiemetics; Apomorphine; Body Weight; Cats; Chlorpromazine; Crowding; Dogs; Humans; Imipramine; Male; Maprotiline; Methamphetamine; Mice; Mice, Inbred Strains; Motor Activity; Rats; Reflex; Reflex, Monosynaptic; Spatial Behavior; Spinal Cord; Stereotyped Behavior | 1975 |
[Electroencephalographic study of maprotiline, a new antidepressive agent].
Topics: Acoustic Stimulation; Amitriptyline; Amygdala; Animals; Anthracenes; Antidepressive Agents; Cerebral Cortex; Chlorpromazine; Electric Stimulation; Electrodes, Implanted; Electroencephalography; Hippocampus; Imipramine; Male; Maprotiline; Mesencephalon; Physostigmine; Rabbits; Reticular Formation; Thalamic Nuclei; Theta Rhythm | 1974 |
Maprotiline and seizures.
Topics: Adult; Anthracenes; Chlorpromazine; Depressive Disorder; Drug Therapy, Combination; Epilepsy, Tonic-Clonic; Humans; Male; Maprotiline | 1982 |
Stedim 6 and Clearflex, two new multilayer materials for infusion containers. Comparative study of their compatibility with five drugs versus glass flasks and polyvinyl chloride bags.
Topics: Adsorption; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Chlorpromazine; Clodronic Acid; Clorazepate Dipotassium; Diazepam; Glass; Infusion Pumps; Maprotiline; Polyethylenes; Polyvinyl Chloride; Silicates; Structure-Activity Relationship | 1995 |
Structure-activity relationships of tricyclic antidepressants and related compounds in the wing somatic mutation and recombination test of Drosophila melanogaster.
Topics: Animals; Antidepressive Agents, Tricyclic; Chlorpromazine; CHO Cells; Clomipramine; Cricetinae; Drosophila melanogaster; Female; Lofepramine; Male; Maprotiline; Mianserin; Mutagenicity Tests; Mutagens; Recombination, Genetic; Structure-Activity Relationship | 1993 |
Interactions between six psychotherapeutic drugs and plastic containers. Influence of plastic material and infusion solutions.
Topics: Chlorpromazine; Clomipramine; Clorazepate Dipotassium; Diazepam; Humans; Infusions, Parenteral; Maprotiline; Polyethylenes; Polyvinyl Chloride; Psychotropic Drugs; Viloxazine | 1993 |
Antipsychotic, antidepressant, anxiolytic, and anticonvulsant drugs induce type II nitric oxide synthase mRNA in rat brain.
Topics: Animals; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Brain; Carbamazepine; Chlorpromazine; Diazepam; Fluvoxamine; Gene Expression; Haloperidol; Isoxazoles; Lithium; Male; Maprotiline; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Zonisamide | 2002 |