chlorpromazine and loxapine

chlorpromazine has been researched along with loxapine in 42 studies

Research

Studies (42)

Timeframe	Studies, this research(%)	All Research%
pre-1990	23 (54.76)	18.7374
1990's	2 (4.76)	18.2507
2000's	12 (28.57)	29.6817
2010's	5 (11.90)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Choudhary, MS; Craigo, SC; Meltzer, HY; Monsma, FJ; Roth, BL; Shen, Y; Sibley, DR; Uluer, A	1
Druck, T; Hamblin, MW; Huebner, K; Khan, N; Kohen, R; Lachowicz, JE; Meltzer, HY; Metcalf, MA; Roth, BL; Sibley, DR	1
Strassburg, CP; Tukey, RH	1
Grinde, E; Herrick-Davis, K; Teitler, M	1
Ernsberger, P; Hufeisen, SJ; Jayathilake, K; Kroeze, WK; Meltzer, HY; Popadak, BA; Renock, SM; Roth, BL; Steinberg, S	1
McKinnon, RA; Miners, JO; Smith, PA; Sorich, MJ	1
Glennon, RA	1
Andaluz, B; Buschmann, H; Codony, X; Cubí, R; Díaz, JL; Dordal, A; Guitart, X; Hernández, E; Hernández, S; Holenz, J; Mas, J; Mercè, R; Monroy, X; Pérez, R; Romero, G; Sánchez, E; Sanfeliu, O; Torrens, A	1
Herrick-Davis, K; Purohit, A; Smith, C; Teitler, M	1
Ahman, M; Holmén, AG; Wan, H	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Dalvie, D; Loi, CM; Smith, DA	1
Bellman, K; Knegtel, RM; Settimo, L	1
Bennis, K; Ducki, S; Lesage, F; Vivier, D	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bishop, MP; Dunnett, CW; Kiltie, H; Simpson, GM	1
Avery, GS; Brogden, RN; Heel, RC; Speight, TM	1
Coupet, J; Rauh, CE	1
Davis, JM	1
Moore, DF	1
Dube, KC; Kumar, N	1
Davis, CM; Fenimore, DC; Meyer, CJ	1
Haher, J; Simpson, GM; Varga, E	1
Schiele, BC	1
Asper, H; Bürki, HR; Ruch, W; Sayers, AC	1
Matsubara, S; Meltzer, HY	1
Andree, TH; Koenig, JI; Meltzer, HY; Mikuni, M; Tong, CY	1
Ricketts, JE; Zisook, S	1
Escobar, JI; Tuason, VB	1
Michael, RP; Schaefer, GJ	1
Dahl, SG	1
Davis, KL; Kendler, KS	1
Escobar, JI; Garvey, M; Schiele, B; Tuason, VB	1
Kane, J; Rieder, E; Rifkin, A; Saraf, K; Sarantakos, S	1
Leone, NF	1
Einarson, TR; Ewing, DG	1
Goudie, AJ; Smith, JA	1
Gabryel, B; Herman, ZS; Kowalski, J; Labuzek, K	1
Burdock, EI; Gershon, S; Hardesty, AS; Linden, KJ	1
Chaaban, R; Collet, F; Lemyze, M	1
Eichelman, BS; Hutchins, LG; Kornguth, ML	1
Lam, D; Patten, SB; Pringsheim, T; Tano, DS	1

Reviews

6 review(s) available for chlorpromazine and loxapine

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7). Journal of medicinal chemistry, 2003, Jul-03, Volume: 46, Issue:14 Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists	2003
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target? Journal of medicinal chemistry, 2016, 06-09, Volume: 59, Issue:11 Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Structure; Neuroprotective Agents; Pain; Potassium Channels, Tandem Pore Domain; Structure-Activity Relationship	2016
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Loxapine: a review of its pharmacological properties and therapeutic efficacy as an antipsychotic agent. Drugs, 1978, Volume: 15, Issue:3 Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Chlorpromazine; Dibenzoxazepines; Drug Interactions; Haloperidol; Humans; Intestinal Absorption; Kinetics; Loxapine; Receptors, Dopamine; Schizophrenia; Thiothixene; Trifluoperazine	1978
Active metabolites of neuroleptic drugs: possible contribution to therapeutic and toxic effects. Therapeutic drug monitoring, 1982, Volume: 4, Issue:1 Topics: Antipsychotic Agents; Biotransformation; Brain; Chlorpromazine; Erythrocytes; Humans; Loxapine; Methotrimeprazine; Thioridazine	1982

Trials

8 trial(s) available for chlorpromazine and loxapine

Article	Year
Efficacy of loxapine in the treatment of paranoid schizophrenia. Psychopharmacology, 1977, Jan-31, Volume: 51, Issue:2 Topics: Adult; Brief Psychiatric Rating Scale; Chlorpromazine; Clinical Trials as Topic; Dibenzoxazepines; Drug Administration Schedule; Drug Evaluation; Female; Humans; Loxapine; Male; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenia, Paranoid; Trifluoperazine	1977
Recent developments in the drug treatment of schizophrenia. The American journal of psychiatry, 1976, Volume: 133, Issue:2 Topics: Chlorpromazine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Evaluation; Drug Resistance; Fluphenazine; Humans; Loxapine; Molindone; Phenothiazines; Placebos; Promazine; Research Design; Schizophrenia; Structure-Activity Relationship; Tranquilizing Agents; Trifluoperazine	1976
Treatment of acute schizophrenia with loxapine succinate (Loxitane) in a controlled study with chlorpromazine. Current therapeutic research, clinical and experimental, 1975, Volume: 18, Issue:1 pt 2 Topics: Acute Disease; Adult; Chlorpromazine; Clinical Trials as Topic; Dibenzoxazepines; Female; Humans; Loxapine; Male; Psychiatric Status Rating Scales; Schizophrenia	1975
Loxapine succinate: a comparative study with chlorpromazine. Current therapeutic research, clinical and experimental, 1976, Volume: 19, Issue:6 Topics: Adolescent; Adult; Chlorpromazine; Clinical Trials as Topic; Dibenzoxazepines; Humans; Loxapine; Male; Mental Status Schedule; Middle Aged; Psychotic Disorders; Time Factors	1976
Loxapine succinate: a controlled double-blind study in chronic schizophrenia. Diseases of the nervous system, 1975, Volume: 36, Issue:7 Topics: Adult; Aged; Amobarbital; Analysis of Variance; Chemical Phenomena; Chemistry; Chlorpromazine; Clinical Trials as Topic; Dibenzoxazepines; Drug Evaluation; Humans; Loxapine; Male; Middle Aged; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenia, Paranoid	1975
Loxapine versus chlorpromazine in paranoid schizophrenia: a double-blind study. The Journal of clinical psychiatry, 1984, Volume: 45, Issue:4 Topics: Adult; Basal Ganglia Diseases; Chlorpromazine; Clinical Trials as Topic; Dibenzoxazepines; Dizziness; Double-Blind Method; Dyskinesia, Drug-Induced; Female; Hospitalization; Humans; Hypotension, Orthostatic; Loxapine; Male; Middle Aged; Psychiatric Status Rating Scales; Schizophrenia, Paranoid	1984
Is loxapine more effective than chlorpromazine in paranoid schizophrenia? The American journal of psychiatry, 1984, Volume: 141, Issue:11 Topics: Adolescent; Adult; Chlorpromazine; Clinical Trials as Topic; Dibenzoxazepines; Double-Blind Method; Female; Hospitalization; Humans; Loxapine; Male; Prospective Studies; Psychiatric Status Rating Scales; Schizophrenia, Paranoid	1984
Response of borderline patients to loxapine and chlorpromazine. The Journal of clinical psychiatry, 1982, Volume: 43, Issue:4 Topics: Adolescent; Adult; Borderline Personality Disorder; Chlorpromazine; Clinical Trials as Topic; Dibenzoxazepines; Double-Blind Method; Female; Humans; Loxapine; Male; Middle Aged; Personality Disorders; Psychiatric Status Rating Scales	1982

Other Studies

28 other study(ies) available for chlorpromazine and loxapine

Article	Year
Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:3 Topics: Animals; Antipsychotic Agents; Cell Line; Molecular Structure; Rats; Receptors, Serotonin	1994
Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor. Journal of neurochemistry, 1996, Volume: 66, Issue:1 Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Antipsychotic Agents; Base Sequence; Brain Chemistry; Cell Line, Transformed; Chlorocebus aethiops; Chromosome Mapping; Chromosomes, Human, Pair 1; Cloning, Molecular; Clozapine; DNA, Complementary; Genes; Humans; Kinetics; Molecular Sequence Data; Open Reading Frames; Protein Conformation; Rats; Receptors, Serotonin; Recombinant Proteins; Sequence Alignment; Sequence Homology, Nucleic Acid; Serotonin Agents; Signal Transduction; Species Specificity	1996
Inverse agonist activity of atypical antipsychotic drugs at human 5-hydroxytryptamine2C receptors. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 295, Issue:1 Topics: Animals; Antipsychotic Agents; COS Cells; Dose-Response Relationship, Drug; Humans; Inositol Phosphates; Radioligand Assay; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Receptor Agonists	2000
H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:3 Topics: Animals; Antipsychotic Agents; Discriminant Analysis; Drug Evaluation, Preclinical; Forecasting; Humans; Protein Binding; Receptors, Histamine H1; Statistics, Nonparametric; Weight Gain	2003
Pharmacophore and quantitative structure-activity relationship modeling: complementary approaches for the rationalization and prediction of UDP-glucuronosyltransferase 1A4 substrate selectivity. Journal of medicinal chemistry, 2003, Apr-24, Volume: 46, Issue:9 Topics: Catalysis; Glucuronides; Glucuronosyltransferase; Humans; Isoenzymes; Models, Molecular; Protein Binding; Quantitative Structure-Activity Relationship; Substrate Specificity	2003
Medicinal chemistry driven approaches toward novel and selective serotonin 5-HT6 receptor ligands. Journal of medicinal chemistry, 2005, Mar-24, Volume: 48, Issue:6 Topics: Adenylyl Cyclases; Benzoxazines; Cell Line; Humans; Indoles; Ligands; Piperidines; Radioligand Assay; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Sulfonamides	2005
Stable expression of constitutively activated mutant h5HT6 and h5HT7 serotonin receptors: inverse agonist activity of antipsychotic drugs. Psychopharmacology, 2005, Volume: 179, Issue:2 Topics: Amino Acid Substitution; Antipsychotic Agents; Cell Line; Cyclic AMP; Humans; Mutagenesis, Site-Directed; Mutation; Radioligand Assay; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection	2005
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs. Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6 Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry	2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Which metabolites circulate? Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:5 Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
3H-Spiroperidol binding to dopamine receptors in rat striatal membranes: influence of loxapine and its hydroxylated metabolites. European journal of pharmacology, 1979, Apr-15, Volume: 55, Issue:2 Topics: Animals; Butyrophenones; Chlorpromazine; Clozapine; Corpus Striatum; Dibenzoxazepines; Haloperidol; Hydroxylation; In Vitro Techniques; Loxapine; Membranes; Rats; Receptors, Dopamine; Spiperone	1979
Improved gas chromatographic analysis of chlorpromazine in blood serum. Clinica chimica acta; international journal of clinical chemistry, 1977, Jul-01, Volume: 78, Issue:1 Topics: Chlorpromazine; Chromatography, Gas; Drug Interactions; Drug Stability; Humans; Loxapine; Promazine; Tranquilizing Agents	1977
Psychotic exacerbations produced by neuroleptics. Diseases of the nervous system, 1976, Volume: 37, Issue:7 Topics: Acute Disease; Antiparkinson Agents; Chlorpromazine; Humans; Loxapine; Psychoses, Substance-Induced; Tranquilizing Agents	1976
Neuroleptic-induced hypersensitivity of striatal dopamine receptors in the rat as a model of tardive dyskinesias. Effects of clozapine, haloperidol, loxapine and chlorpromazine. Psychopharmacologia, 1975, Volume: 41, Issue:2 Topics: Animals; Apomorphine; Chlorpromazine; Clozapine; Corpus Striatum; Dibenzazepines; Dibenzoxazepines; Disease Models, Animal; Dopamine; Drug Tolerance; Female; Haloperidol; Homovanillic Acid; Humans; Loxapine; Male; Movement Disorders; Rats; Receptors, Drug; Stereotyped Behavior; Substance Withdrawal Syndrome	1975
Effect of typical and atypical antipsychotic drugs on 5-HT2 receptor density in rat cerebral cortex. Life sciences, 1989, Volume: 45, Issue:15 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antipsychotic Agents; Butyrophenones; Cerebral Cortex; Chlorpromazine; Clozapine; Dibenzazepines; Dibenzothiazepines; Down-Regulation; Flupenthixol; Kinetics; Loxapine; Male; Pyrimidinones; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiro Compounds; Time Factors	1989
Differential effect of subchronic treatment with various neuroleptic agents on serotonin2 receptors in rat cerebral cortex. Journal of neurochemistry, 1986, Volume: 46, Issue:1 Topics: 5,7-Dihydroxytryptamine; Animals; Antipsychotic Agents; Cerebral Cortex; Chlorpromazine; Clozapine; Female; Haloperidol; Imipramine; Ketanserin; Loxapine; Male; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Spiperone; Sulpiride	1986
Psychopharmacologic approaches to the borderline patient. The Hillside journal of clinical psychiatry, 1988, Volume: 10, Issue:1 Topics: Adult; Amphetamines; Antipsychotic Agents; Borderline Personality Disorder; Chlorpromazine; Female; Humans; Lithium; Loxapine; Monoamine Oxidase Inhibitors; Personality Disorders; Psychotropic Drugs	1988
How effective is loxapine? The American journal of psychiatry, 1986, Volume: 143, Issue:1 Topics: Chlorpromazine; Depression; Dibenzoxazepines; Humans; Loxapine; Psychiatric Status Rating Scales; Schizophrenia, Paranoid	1986
Acute effects of neuroleptics on brain self-stimulation thresholds in rats. Psychopharmacology, 1980, Volume: 67, Issue:1 Topics: Animals; Antipsychotic Agents; Brain; Chlorpromazine; Clozapine; Haloperidol; Loxapine; Male; Pimozide; Rats; Self Stimulation	1980
Acute and chronic effects of neuroleptic drugs on plasma and brain homovanillic acid in the rat. Psychiatry research, 1984, Volume: 13, Issue:1 Topics: Animals; Antipsychotic Agents; Brain Chemistry; Chlorpromazine; Fluphenazine; Haloperidol; Homovanillic Acid; Loxapine; Male; Metoclopramide; Molindone; Phenylacetates; Rats; Rats, Inbred Strains; Sulpiride	1984
Loxapine as an alternative to phenothiazines in a case of oculocutaneous skin pigmentation. The American journal of psychiatry, 1981, Volume: 138, Issue:12 Topics: Chlorpromazine; Chronic Disease; Dibenzoxazepines; Eye Color; Humans; Loxapine; Male; Middle Aged; Photosensitivity Disorders; Schizophrenia; Skin Pigmentation	1981
Discriminative stimulus properties in rats of the novel antipsychotic quetiapine. Experimental and clinical psychopharmacology, 2002, Volume: 10, Issue:4 Topics: Amisulpride; Analysis of Variance; Animals; Antipsychotic Agents; Chlorpromazine; Clozapine; Dibenzothiazepines; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Female; Generalization, Psychological; Haloperidol; Loxapine; Quetiapine Fumarate; Quinoxalines; Rats; Rats, Wistar; Risperidone; Sulpiride	2002
Chlorpromazine and loxapine reduce interleukin-1beta and interleukin-2 release by rat mixed glial and microglial cell cultures. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2005, Volume: 15, Issue:1 Topics: Analysis of Variance; Animals; Animals, Newborn; Antipsychotic Agents; Cells, Cultured; Cerebral Cortex; Chlorpromazine; Dopamine Agonists; Dose-Response Relationship, Drug; Interleukin-1; Interleukin-2; Loxapine; Neuroglia; Quinpirole; Rats; Rats, Wistar; Time Factors	2005
Problems and profits of cross-national collaborative studies. Diseases of the nervous system, 1974, Volume: 35, Issue:7 Pt. 2 Topics: Acute Disease; Antipsychotic Agents; Chlorpromazine; Controlled Clinical Trials as Topic; Feasibility Studies; Germany, West; Humans; Internationality; Loxapine; Multicenter Studies as Topic; Pilot Projects; Research Design; Schizophrenia; Switzerland; United States	1974
Psychotic woman with painful abdominal distension. Life-threatening psychotropic drug-induced gastrointestinal hypomotility. Annals of emergency medicine, 2009, Volume: 54, Issue:5 Topics: Abdomen, Acute; Antipsychotic Agents; Chlorpromazine; Cholinergic Antagonists; Critical Illness; Digestive System Surgical Procedures; Drug Therapy, Combination; Emergency Service, Hospital; Female; Gastrointestinal Diseases; Gastrointestinal Motility; Humans; Intestinal Pseudo-Obstruction; Loxapine; Magnetic Resonance Imaging; Middle Aged; Psychotic Disorders; Risk Assessment; Tomography, X-Ray Computed; Treatment Outcome	2009
Binding of psychotropic drugs to isolated alpha-acid glycoprotein. Biochemical pharmacology, 1981, Sep-01, Volume: 30, Issue:17 Topics: Binding, Competitive; Chlorpromazine; Fluphenazine; Humans; Imipramine; Kinetics; Loxapine; Molindone; Orosomucoid; Protein Binding; Psychotropic Drugs; Thioridazine; Thiothixene; Trihexyphenidyl	1981
The pharmacoepidemiology of antipsychotics for adults with schizophrenia in Canada, 2005 to 2009. Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2011, Volume: 56, Issue:10 Topics: Adult; Antipsychotic Agents; Benzodiazepines; Canada; Chlorpromazine; Clopenthixol; Clozapine; Female; Flupenthixol; Humans; Loxapine; Male; Olanzapine; Pharmacoepidemiology; Schizophrenia	2011