chlorpromazine and ketamine

chlorpromazine has been researched along with ketamine in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199015 (42.86)18.7374
1990's4 (11.43)18.2507
2000's7 (20.00)29.6817
2010's9 (25.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
Faller, B; Trunzer, M; Zimmerlin, A1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Buckle, P; Jameson, D1
Friedman, SJ; Skehan, P1
Hiller, HH; Merkenschlager, M1
Methfessel, G; Methfessel, HD1
Gillis, MF; Ragan, HA1
Clift, PS; Scavio, MJ; Wills, JC1
Johnson, KM; Snell, LD1
Byrd, LD; Howell, LL; Standish, LJ1
Roy, RK; Uppal, RP1
Davis, H1
Browne, R; Carrell, T; Fixler, DE; Miller, WW; Willis, K1
Henriksson, BG; Järbe, TU1
Hatch, RC1
Laird, SM; Sage, M1
Deppe, R; Mercado, P; Thibaut, J1
Nigam, JM; Pathak, SC; Peshin, PK; Singh, AP1
Marx, CM; Petrack, EM; Wright, MS1
Gupta, MC; Singh, J1
Bakshi, V; Geyer, MA; Swerdlow, NR; Taaid, N; Waikar, M1
Auden, SM; Goldsmith, LJ; Sobczyk, WL; Solinger, RE1
Fatemi, SH; Patterson, PH; Shi, L; Sidwell, RW1
Cassu, RN; Castro, GB; Lopes, MD; Luna, SP; Silva Júnior, JR; Teixeira Neto, FJ1
Ates, N; Ilbay, G; Sahin, D; Ubeyli, ED1
Cheng, W; Li, LK; Liu, DH; Qiao, CH; Zhang, J; Zhang, YB; Zhu, YB1
Barbosa, TM; Borges, LTN; Gularte, VN; Lima, RF; Macêdo, D; Matos, NCB; Oliveira, MN; Patrocínio, MCA; Sampaio, LRL; Vale, OCD; Vasconcelos, SMM1
Cysne Filho, FMS; de Almeida, JC; de Sousa, CNS; Diniz, DDS; Macêdo, D; Patrocínio, CFV; Patrocínio, MCA; Sampaio, LRL; Vasconcelos, SMM1

Reviews

3 review(s) available for chlorpromazine and ketamine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Elimination of pain in laboratory animals].
    Berliner und Munchener tierarztliche Wochenschrift, 1975, Aug-01, Volume: 88, Issue:15

    Topics: Acepromazine; Anesthesia, General; Anesthetics; Animals; Animals, Laboratory; Azaperone; Chloroform; Chlorpromazine; Cricetinae; Dose-Response Relationship, Drug; Droperidol; Ethers; Gerbillinae; Guinea Pigs; Halothane; Hexobarbital; Imidazoles; Ketamine; Lethal Dose 50; Methoxyflurane; Mice; Pentobarbital; Rabbits; Rats; Swine; Urethane

1975
Restraint, venipuncture, endotracheal intubation, and anesthesia of miniature swine.
    Laboratory animal science, 1975, Volume: 25, Issue:4

    Topics: Anesthesia; Anesthesia, Epidural; Anesthesia, Inhalation; Animals; Animals, Laboratory; Bloodletting; Chlordiazepoxide; Chlorpromazine; Diazepam; Droperidol; Electronarcosis; Fentanyl; Immobilization; Intubation, Intratracheal; Ketamine; Meperidine; Pentobarbital; Phencyclidine; Preanesthetic Medication; Punctures; Swine; Swine Diseases; Thiopental; Vena Cava, Superior

1975

Trials

2 trial(s) available for chlorpromazine and ketamine

ArticleYear
Intramuscular ketamine is superior to meperidine, promethazine, and chlorpromazine for pediatric emergency department sedation.
    Archives of pediatrics & adolescent medicine, 1996, Volume: 150, Issue:7

    Topics: Child; Child, Preschool; Chlorpromazine; Conscious Sedation; Double-Blind Method; Drug Therapy, Combination; Emergency Service, Hospital; Female; Hemodynamics; Humans; Infant; Injections, Intramuscular; Ketamine; Male; Meperidine; Patient Satisfaction; Promethazine; Prospective Studies

1996
Oral ketamine/midazolam is superior to intramuscular meperidine, promethazine, and chlorpromazine for pediatric cardiac catheterization.
    Anesthesia and analgesia, 2000, Volume: 90, Issue:2

    Topics: Adjuvants, Anesthesia; Administration, Oral; Cardiac Catheterization; Child; Child, Preschool; Chlorpromazine; Double-Blind Method; Hemodynamics; Humans; Hypnotics and Sedatives; Infant; Injections, Intramuscular; Ketamine; Meperidine; Midazolam; Promethazine

2000

Other Studies

30 other study(ies) available for chlorpromazine and ketamine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Metabolic soft spot identification and compound optimization in early discovery phases using MetaSite and LC-MS/MS validation.
    Journal of medicinal chemistry, 2009, Jan-22, Volume: 52, Issue:2

    Topics: Chromatography, Liquid; Drug Design; Humans; Likelihood Functions; Microsomes, Liver; Pharmacokinetics; Tandem Mass Spectrometry

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
A comparison of anti-inflammatory and other compounds on the spontaneously contracting pregnant rat uterus.
    The Journal of pharmacy and pharmacology, 1977, Volume: 29, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Chlorpromazine; Desipramine; Diazepam; Female; In Vitro Techniques; Ketamine; Muscle, Smooth; Papaverine; Pregnancy; Pregnancy, Animal; Rats; Uterine Contraction

1977
The inhibition of sterol synthesis by anesthetics.
    FEBS letters, 1979, Jun-15, Volume: 102, Issue:2

    Topics: Acetates; Anesthetics, Local; Animals; Cell Line; Chlorpromazine; Diphenylacetic Acids; Glioma; Haloperidol; Ketamine; Lidocaine; Lipids; Pentobarbital; Rats; Sterols; Tetracaine

1979
[Action of some drugs on pressure profile of female urethra (author's transl)].
    Zentralblatt fur Gynakologie, 1979, Volume: 101, Issue:22

    Topics: Adolescent; Adult; Butylscopolammonium Bromide; Chlorpromazine; Diazepam; Drug Synergism; Female; Humans; Ketamine; Male; Parasympatholytics; Phentolamine; Pressure; Succinylcholine; Urethra

1979
Posttraining effects of amphetamine, chlorpromazine, ketamine, and scopolamine on the acquisition and extinction of the rabbit's conditioned nictitating membrane response.
    Behavioral neuroscience, 1992, Volume: 106, Issue:6

    Topics: Animals; Arousal; Association Learning; Brain; Chlorpromazine; Conditioning, Classical; Conditioning, Eyelid; Dextroamphetamine; Dose-Response Relationship, Drug; Extinction, Psychological; Female; Ketamine; Male; Mental Recall; Pitch Perception; Rabbits; Reaction Time; Retention, Psychology; Scopolamine

1992
Antagonism of N-methyl-D-aspartate-induced transmitter release in the rat striatum by phencyclidine-like drugs and its relationship to turning behavior.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:1

    Topics: Acetylcholine; Amphetamine; Animals; Apomorphine; Aspartic Acid; Benzomorphans; Chlorpromazine; Clozapine; Corpus Striatum; Cyclazocine; Dioxolanes; Dopamine; Haloperidol; Ketamine; Male; Mathematics; Motor Activity; N-Methylaspartate; Phencyclidine; Posture; Rats; Rats, Inbred Strains; Substantia Nigra

1985
Behavioral effects of phencyclidine and ketamine alone and in combination with other drugs.
    European journal of pharmacology, 1987, Dec-15, Volume: 144, Issue:3

    Topics: Animals; Atropine; Atropine Derivatives; Behavior, Animal; Chlorpromazine; Dextroamphetamine; Drug Interactions; Ketamine; Male; Naloxone; Phencyclidine; Saimiri

1987
Neurobehavioural effects of ketamine.
    Indian journal of experimental biology, 1986, Volume: 24, Issue:5

    Topics: Animals; Apomorphine; Behavior, Animal; Chlorpromazine; Hypnotics and Sedatives; Ketamine; Mice; Motor Activity; Rats; Rats, Inbred Strains; Sleep

1986
Sedation of young children for electric response audiometry (ERA). Summary of a symposium.
    Audiology : official organ of the International Society of Audiology, 1973, Volume: 12, Issue:1

    Topics: Age Factors; Anesthesia, Inhalation; Audiometry; Barbiturates; Cerebral Cortex; Child; Child, Preschool; Chloral Hydrate; Chlorpromazine; Congresses as Topic; Diazepam; Diphenhydramine; Evoked Potentials; Haloperidol; Halothane; Humans; Hydroxybutyrates; Hydroxyzine; Hypnotics and Sedatives; Infant; Ketamine; Methaqualone; Nitrous Oxide; Promazine; Promethazine; Sleep

1973
Oxygen consumption in infants and children during cardiac catheterization under different sedation regimens.
    Circulation, 1974, Volume: 50, Issue:4

    Topics: Age Factors; Anesthesia; Anesthesia, Intravenous; Anesthetics; Atropine; Body Surface Area; Body Temperature; Body Weight; Cardiac Catheterization; Child; Child, Preschool; Chlorpromazine; Humans; Infant; Infusions, Parenteral; Ketamine; Mathematics; Meperidine; Methods; Morphine; Nitrogen; Oxygen Consumption; Pentobarbital; Preanesthetic Medication; Promethazine; Regression Analysis

1974
Discriminative response control produced with hashish, tetrahydrocannabinols (delta 8-THC and delta 9-THC), and other drugs.
    Psychopharmacologia, 1974, Volume: 40, Issue:1

    Topics: Amphetamine; Animals; Atropine; Avoidance Learning; Cannabis; Chlordiazepoxide; Chlorpromazine; Choice Behavior; Cocaine; Cues; Diazepam; Discrimination, Psychological; Dronabinol; Ketamine; Levallorphan; Male; Morphine; Pentobarbital; Phencyclidine; Physostigmine; Psilocybin; Rats; Scopolamine; Transfer, Psychology; Yohimbine

1974
Ketamine catalepsy and anesthesia in dogs pretreated with antiserotonergic or antidopaminergic neuroleptics or with anticholinergic agents.
    Pharmacological research communications, 1974, Volume: 6, Issue:3

    Topics: Anesthesia; Animals; Atropine; Catalepsy; Chlorpromazine; Dibenzothiepins; Dihydroxyphenylalanine; Dogs; Drug Synergism; Female; Humans; Ketamine; Male; Mecamylamine; Muscle Tonus; Parasympatholytics; Pimozide; Piperazines; Reflex; Respiration; Serotonin Antagonists; Sulfides

1974
Psychosis and ketamine.
    British medical journal, 1972, Jan-22, Volume: 1, Issue:5794

    Topics: Adult; Anesthetics; Bipolar Disorder; Burns; Chlorpromazine; Cyclohexanes; Female; Humans; Ketamine; Preanesthetic Medication

1972
[Combined use of ketamine and chlorpromazine in the dog].
    Zentralblatt fur Veterinarmedizin. Reihe A, 1982, Volume: 29, Issue:8

    Topics: Anesthesia, General; Animals; Chlorpromazine; Dogs; Female; Heart; Injections, Intramuscular; Ketamine; Male; Respiration

1982
Anesthetic and hemodynamic effects of ketamine hydrochloride in buffalo calves (Bubalus bubalis).
    American journal of veterinary research, 1982, Volume: 43, Issue:5

    Topics: Animals; Blood Pressure; Buffaloes; Chlorpromazine; Heart Rate; Hemodynamics; Ketamine; Vascular Resistance

1982
Effect of aspartate and glutamate on nociception, catalepsy and core temperature in rats.
    Indian journal of physiology and pharmacology, 1997, Volume: 41, Issue:2

    Topics: Adrenergic Uptake Inhibitors; Analgesia; Analgesics, Opioid; Animals; Aspartic Acid; Body Temperature; Catalepsy; Chlorpromazine; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fever; Glutamic Acid; Haloperidol; Hypothermia; Injections, Subcutaneous; Ketamine; Male; Morphine; Naloxone; Narcotic Antagonists; Nociceptors; Rats; Reserpine; Trifluoperazine

1997
Seroquel, clozapine and chlorpromazine restore sensorimotor gating in ketamine-treated rats.
    Psychopharmacology, 1998, Volume: 140, Issue:1

    Topics: Animals; Antipsychotic Agents; Chlorpromazine; Clozapine; Dibenzothiazepines; Dose-Response Relationship, Drug; Haloperidol; Ketamine; Male; Quetiapine Fumarate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex, Startle

1998
Maternal influenza infection causes marked behavioral and pharmacological changes in the offspring.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Jan-01, Volume: 23, Issue:1

    Topics: Acoustic Stimulation; Animals; Animals, Newborn; Antipsychotic Agents; Antiviral Agents; Anxiety; Behavior, Animal; Chlorpromazine; Clozapine; Exploratory Behavior; Female; Immunity; Ketamine; Maternal-Fetal Relations; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Motor Activity; Orthomyxoviridae Infections; Poly I-C; Pregnancy; Social Behavior

2003
Effects of four anaesthetic protocols on the neurological and cardiorespiratory variables of puppies born by caesarean section.
    The Veterinary record, 2004, Mar-27, Volume: 154, Issue:13

    Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Combined; Animals; Bupivacaine; Cesarean Section; Chlorpromazine; Dogs; Enflurane; Epinephrine; Female; Heart Rate; Ketamine; Lidocaine; Midazolam; Pregnancy; Propofol; Random Allocation; Reflex; Respiration; Thiopental

2004
Discrete wavelet transform for analysis of spike-wave discharges in rats.
    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2008, Volume: 2008

    Topics: Algorithms; Animals; Chlorpromazine; Data Interpretation, Statistical; Electrodes; Electrodes, Implanted; Electroencephalography; Ketamine; Male; Models, Statistical; Models, Theoretical; Rats; Rats, Wistar; Reproducibility of Results

2008
A novel, recovery, and reproducible minimally invasive cardiopulmonary bypass model with lung injury in rats.
    Chinese medical journal, 2013, Volume: 126, Issue:24

    Topics: Animals; Cardiopulmonary Bypass; Chlorpromazine; Electrocardiography; Ketamine; Lung Injury; Minimally Invasive Surgical Procedures; Models, Animal; Rats; Rats, Sprague-Dawley

2013
Electroencephalographic study of chlorpromazine alone or combined with alpha-lipoic acid in a model of schizophrenia induced by ketamine in rats.
    Journal of psychiatric research, 2017, Volume: 86

    Topics: Analysis of Variance; Animals; Antipsychotic Agents; Brain; Chlorpromazine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Therapy, Combination; Electrocorticography; Electrodes, Implanted; Ketamine; Male; Random Allocation; Rats, Wistar; Schizophrenia; Thioctic Acid; Time Factors

2017
Advantages of the Alpha-lipoic Acid Association with Chlorpromazine in a Model of Schizophrenia Induced by Ketamine in Rats: Behavioral and Oxidative Stress evidences.
    Neuroscience, 2018, 03-01, Volume: 373

    Topics: Animals; Antioxidants; Antipsychotic Agents; Chlorpromazine; Disease Models, Animal; Drug Therapy, Combination; Hippocampus; Ketamine; Lipid Peroxidation; Male; Memory, Short-Term; Motor Activity; Nitriles; Oxidative Stress; Prepulse Inhibition; Random Allocation; Rats, Wistar; Schizophrenia; Thioctic Acid

2018