chlorpromazine and isomethyleugenol

chlorpromazine has been researched along with isomethyleugenol in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199031 (81.58)18.7374
1990's4 (10.53)18.2507
2000's1 (2.63)29.6817
2010's1 (2.63)24.3611
2020's1 (2.63)2.80

Authors

AuthorsStudies
Gescher, A; Li Wan Po, A1
Melzacka, M; Nocon, H1
Messiha, FS1
Bedale, WA; Nettleton, DO; Ordal, GW; Thoelke, MS1
Borowitz, JL; Proakis, AG1
Barth, H; Lorenz, W; Werle, E1
Hackenberg, H; Krieglstein, J1
Valzelli, L1
Daly, JW; Manian, AA1
Clark, B; Thompson, JW; Widdrington, G1
Boakes, RJ; Candy, JM; Key, BJ; Worton, E1
Bowers, MB; Extein, I; Roth, RH1
Horn, AS; Trace, RC1
Lin, RL; Narasimhachari, N1
Beckett, AH; Gorrod, JW; Lazarus, CR1
Brookes, LG; Forrest, IS1
Breyer, U; Gaertner, HJ; Prox, A1
Kirkpatrick, WE; Lomax, P2
Heisler, S; Kovacs, EM2
Scheel-Krüger, J1
Beckett, AH; Hewick, DS1
Bhatnagar, SP1
Ganguly, DK1
Efron, DH; Gaudette, LE; Harris, SR; Manian, AA1
Ahtee, L; Paasonen, MK1
Spoerlein, MT; VanderWende, C1
Barber, JR; Clarke, S1
Mostafa, MH; Ruchirawat, M; Weisburger, EK1
Alemany, S; Harper, JF; Mato, JM; Varela, I1
Bianchi, L; Della Corte, L; Frosini, M; Giovannini, MG; Palmi, M; Sgaragli, GP; Valoti, M1
Hover, CG; Kulkarni, AP; Rajadhyaksha, AV; Reddy, V1
Hover, CG; Kulkarni, AP1
WHITE, T1
AXELROD, J; SNYDER, SH1
Andreu, I; Coloma, MD; Escobar, J; Garcia-Lainez, G; Jiménez, MC; Limones-Herrero, D; Miranda, MA; Palumbo, F1
Andreu, I; González-Bello, C; Jiménez, MC; Lence, E; Limones-Herrero, D; Miranda, MA; Palumbo, F; Vendrell-Criado, V1

Reviews

1 review(s) available for chlorpromazine and isomethyleugenol

ArticleYear
Psychoactive drugs and brain neurochemical transmitters.
    Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 196

    Topics: Amphetamine; Antidepressive Agents; Butyrophenones; Chlorpromazine; Deamination; Desipramine; Dihydroxyphenylalanine; Methylation; Neurons; Norepinephrine; Phenothiazines; Receptors, Drug; Reserpine; Synapses; Synaptic Transmission; Tyrosine

1972

Other Studies

37 other study(ies) available for chlorpromazine and isomethyleugenol

ArticleYear
Correlation of physicochemical properties with absorption and metabolism of some tricyclic drugs.
    The Journal of pharmacy and pharmacology, 1978, Volume: 30, Issue:6

    Topics: Absorption; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Chlorpromazine; Doxepin; Imipramine; In Vitro Techniques; Male; Methylation; Phenothiazines; Promazine; Promethazine; Rats; Surface Tension

1978
Effect of some cationic amphiphilic drugs on phospholipid methylation in the central nervous system of rats.
    The Journal of pharmacy and pharmacology, 1991, Volume: 43, Issue:2

    Topics: Animals; Cerebral Cortex; Chlorpromazine; Citalopram; Desipramine; Imipramine; Injections, Intraperitoneal; Male; Methylation; Methyltransferases; Phospholipids; Rats; Rats, Inbred Strains; Synaptic Membranes

1991
Genotype-treatment interaction between amantadine and chlorpromazine in the mouse.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1991, Volume: 99, Issue:3

    Topics: Amantadine; Animals; Biogenic Amines; Brain; Chlorpromazine; Dopamine; Drug Interactions; Genotype; Hydroxyindoleacetic Acid; Methoxyhydroxyphenylglycol; Methylation; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Motor Activity; Normetanephrine; Serotonin; Time Factors

1991
Evidence for an intermediate methyl-acceptor for chemotaxis in Bacillus subtilis.
    The Journal of biological chemistry, 1987, Feb-25, Volume: 262, Issue:6

    Topics: Aspartic Acid; Bacillus subtilis; Bacterial Proteins; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Chemotaxis; Chlorpromazine; Membrane Proteins; Methanol; Methyl-Accepting Chemotaxis Proteins; Methylation

1987
Blockade of insulin release by certain phenothiazines.
    Biochemical pharmacology, 1974, Jun-15, Volume: 23, Issue:12

    Topics: Adrenal Glands; Adrenalectomy; Animals; Antigens; Antipsychotic Agents; Blood Glucose; Chlorpromazine; Dose-Response Relationship, Drug; Fluphenazine; Glucose; Insulin Antagonists; Male; Methylation; Pancreas; Perfusion; Stimulation, Chemical; Time Factors

1974
Histamine and histamine methyltransferase in the gastric mucosa of man, pig, dog and cow.
    Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1970, Volume: 267, Issue:5

    Topics: Animals; Cattle; Chlorpromazine; Chromatography, Thin Layer; Dogs; Fluorometry; Gastric Mucosa; Histamine; Humans; Hydrogen-Ion Concentration; Kinetics; Methylation; N-Glycosyl Hydrolases; Swine; Transferases

1970
Comparative study on the inhibition of Na + , K + -activated ATPase activity by chlorpromazine, promazine, imipramine, and their monodesmethyl metabolites.
    Naunyn-Schmiedeberg's archives of pharmacology, 1972, Volume: 274, Issue:1

    Topics: Adenosine Triphosphatases; Animals; Brain; Chlorpromazine; Enzyme Activation; Female; Imipramine; Methylation; Microsomes; Potassium; Promazine; Protein Binding; Rats; Receptors, Drug; Sodium

1972
The metabolism of hydroxychlorpromazines by rat liver microsomes.
    Biochemical pharmacology, 1967, Volume: 16, Issue:11

    Topics: Acetophenones; Animals; Carbon Isotopes; Chlorpromazine; Chromatography, Thin Layer; Hydroxides; In Vitro Techniques; Liver; Methylation; Microsomes; NADP; Phenols; Phenothiazines; Rabbits

1967
Analysis of the inhibition of pethidine N-demethylation by monoamine oxidase inhibitors and some other drugs with special reference to drug interactions in man.
    British journal of pharmacology, 1972, Volume: 44, Issue:1

    Topics: Amphetamine; Animals; Chlorpromazine; Desipramine; Drug Interactions; Histamine; Hydrazines; Hydrocortisone; Imipramine; Iproniazid; Male; Meperidine; Methylation; Microsomes, Liver; Monoamine Oxidase Inhibitors; Nialamide; Opipramol; Phenothiazines; Phenylhydrazines; Prednisolone; Proadifen; Promazine; Rats; Transferases

1972
Correlation of the release of amines and antagonists with their effects.
    Neuropharmacology, 1974, Volume: 13, Issue:6

    Topics: Animals; Autoradiography; Biogenic Amines; Brain; Brain Chemistry; Carbon Radioisotopes; Cats; Chlorpromazine; Diffusion; Electroencephalography; Fluorescence; In Vitro Techniques; Iontophoresis; Kinetics; Methylation; Molecular Weight; Neurons; Norepinephrine; Radioisotopes; Regression Analysis; Sodium Isotopes; Sulfur Radioisotopes

1974
Accumulation of 3H-homovanillic acid in rabbit brain and cerebrospinal fluid following intravenous 3H-L-dopa.
    Biological psychiatry, 1974, Volume: 9, Issue:2

    Topics: Animals; Brain; Brain Chemistry; Carboxy-Lyases; Cerebrospinal Fluid; Chlorpromazine; Chromatography, Thin Layer; Deamination; Decarboxylation; Dihydroxyphenylalanine; Dopamine; Homovanillic Acid; Injections, Intravenous; Male; Methylation; Neurons; Phenylacetates; Probenecid; Rabbits; Stimulation, Chemical; Time Factors; Tritium

1974
Structure-activity relations for the inhibition of 5-hydroxytryptamine uptake by tricyclic antidepressants into synaptosomes from serotoninergic neurones in rat brain homogenates.
    British journal of pharmacology, 1974, Volume: 51, Issue:3

    Topics: Amitriptyline; Animals; Antidepressive Agents; Brain Chemistry; Chlorpromazine; Hypothalamus; Imipramine; In Vitro Techniques; Iprindole; Methylation; Neurons; Nortriptyline; Promazine; Rats; Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Synaptosomes

1974
A possible mechanism for the antischizophrenic action of chlorpromazine: inhibition of the formation of dimethyltryptamine by chlorpromazine metabolites.
    Research communications in chemical pathology and pharmacology, 1974, Volume: 8, Issue:2

    Topics: Animals; Carbon Radioisotopes; Chlorpromazine; Chromatography, Gas; Chromatography, Thin Layer; Desipramine; Hallucinogens; Humans; Imipramine; In Vitro Techniques; Indoles; Lung; Mass Spectrometry; Methylation; Methyltransferases; N,N-Dimethyltryptamine; Rabbits; S-Adenosylmethionine; Schizophrenia; Serotonin; Solvents; Tetrahydrofolates; Time Factors; Tryptamines

1974
Inhibition of the alternative pathways of chlorpromazine metabolism in vitro.
    The Biochemical journal, 1972, Volume: 130, Issue:1

    Topics: Animals; Biotransformation; Chlorpromazine; Chromatography, Thin Layer; Guinea Pigs; In Vitro Techniques; Methylation; Microsomes, Liver; Oxidation-Reduction

1972
Intra-species variation in chlorpromazine metabolism.
    Research communications in chemical pathology and pharmacology, 1973, Volume: 5, Issue:3

    Topics: Age Factors; Animals; Caniformia; Chlorpromazine; Deamination; Guinea Pigs; Horses; Humans; Hydroxylation; Methylation; Microsomes, Liver; Oxidation-Reduction; Rats; Species Specificity

1973
Formation of identical metabolites from piperazine- and dimethylamino-substituted phenothiazine drugs in man, rat and dog.
    Biochemical pharmacology, 1974, Jan-15, Volume: 23, Issue:2

    Topics: Animals; Biotransformation; Chlorpromazine; Chromatography, Thin Layer; Dimethylamines; Dogs; Female; Fluphenazine; Humans; Male; Mass Spectrometry; Methylation; Perphenazine; Phenothiazines; Piperazines; Prochlorperazine; Promazine; Propylamines; Rats; Sulfoxides; Trifluoperazine; Triflupromazine

1974
Interactions of chlorpromazine with monoamines in the hypothalamic thermoregulatory centers.
    Advances in biochemical psychopharmacology, 1974, Volume: 9, Issue:0

    Topics: Acetylcholine; Animals; Aorta; Biogenic Amines; Body Temperature; Body Temperature Regulation; Cerebral Ventricles; Chlorpromazine; Dose-Response Relationship, Drug; Ganglia, Spinal; Hypothalamus; Ileum; In Vitro Techniques; Injections, Intraperitoneal; Methylation; Microinjections; Muscle Contraction; Neural Conduction; Norepinephrine; Receptors, Adrenergic; Receptors, Cholinergic; Time Factors

1974
The possible role of histamine in the coritsone induced gastric acid hypersecretion of the guinea-pig.
    British journal of pharmacology, 1969, Volume: 35, Issue:3

    Topics: Amine Oxidase (Copper-Containing); Animals; Chlorpromazine; Cortisone; Gastric Juice; Guanidines; Guinea Pigs; Heparin; Histamine; Iproniazid; Methylation; Methyldopa; Pylorus

1969
Studies on the accumulation of O-methylated dopamine and noradrenaline in the rat brain following various neuroleptics, thymoleptics and aceperone.
    Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 195, Issue:2

    Topics: Acetamides; Animals; Antidepressive Agents; Benzimidazoles; Brain; Brain Chemistry; Butyrophenones; Chlorpromazine; Chlorprothixene; Desipramine; Dopamine; Imipramine; Ketones; Male; Methylation; Norepinephrine; Normetanephrine; Pargyline; Piperidines; Rats; Stimulation, Chemical; Tranquilizing Agents; Tyramine

1972
The metabolism in vitro of phenothiazine drugs.
    The Biochemical journal, 1971, Volume: 122, Issue:5

    Topics: Animals; Chlorpromazine; Hydroxylation; In Vitro Techniques; Male; Methylation; Microsomes, Liver; Phenothiazines; Prochlorperazine; Rats; Trifluoperazine; Trimeprazine

1971
The metabolism of chlorpromazine by developing rabbit liver.
    Canadian journal of physiology and pharmacology, 1971, Volume: 49, Issue:7

    Topics: Age Factors; Animals; Animals, Newborn; Biotransformation; Chlorpromazine; Chromatography, Thin Layer; Drug Interactions; Ethionine; Humans; Hydroxylation; In Vitro Techniques; Infant, Newborn; Liver; Methylation; Microsomes, Liver; Morphine; Perfusion; Phenobarbital; Rabbits; Stimulation, Chemical; Sulfides; Sulfoxides; Time Factors

1971
Comparison of the effects of procaine, chlorpromazine and their quaternary derivatives on nerve action potentials.
    Research communications in chemical pathology and pharmacology, 1970, Volume: 1, Issue:1

    Topics: Action Potentials; Animals; Anura; Chlorpromazine; Electric Stimulation; Evoked Potentials; Methylation; Neural Conduction; Procaine; Rana pipiens; Sciatic Nerve

1970
Effect of methyl amphetamine on the brain 5-hydroxytryptamine content of isolated and aggregated rats.
    Experientia, 1969, Nov-15, Volume: 25, Issue:11

    Topics: Amphetamine; Animals; Brain Chemistry; Chlorpromazine; Injections, Intraperitoneal; Methylation; Rats; Serotonin

1969
Detection and possible role of a chain methylated histamine metabolite(s) in guinea-pig stomach.
    European journal of pharmacology, 1970, Volume: 11, Issue:3

    Topics: Amino Acids; Animals; Carbon Isotopes; Chlorpromazine; Chromatography, Paper; Cortisone; Gastric Acidity Determination; Gastric Juice; Gastric Mucosa; Guanidines; Guinea Pigs; Histamine; Male; Methylation; Pylorus; Stomach; Tissue Extracts

1970
Radioassay of chlorpromazine and its metabolites in plasma.
    Psychopharmacologia, 1971, Volume: 19, Issue:3

    Topics: Acetates; Animals; Carbon Isotopes; Chemical Phenomena; Chemistry; Chlorpromazine; Dogs; Humans; Methods; Methylation; Protein Binding; Radiometry; Sulfoxides; Tritium

1971
Potentiation of 5-hydroxytryptamine release from platelets by desmethylation of chlorpromazine and related agents.
    Acta pharmacologica et toxicologica, 1968, Volume: 26, Issue:3

    Topics: Amitriptyline; Animals; Blood Platelets; Chlorpromazine; Drug Synergism; Imipramine; Methylation; Nortriptyline; Rabbits; Serotonin

1968
Nature of the tremors induced by p-methoxydopamine.
    Life sciences, 1967, Oct-01, Volume: 6, Issue:19

    Topics: Animals; Chlorpromazine; Dopamine; Male; Methylation; Mice; Movement; Parasympatholytics; Phenobarbital; Propranolol; Tremor

1967
Membrane protein carboxyl methylation does not appear to be involved in the response of erythrocytes to cytoskeletal stress.
    Biochemical and biophysical research communications, 1984, Aug-30, Volume: 123, Issue:1

    Topics: 2,4-Dinitrophenol; Calcimycin; Calcium; Chlorpromazine; Cytoskeleton; Dinitrophenols; Edetic Acid; Egtazic Acid; Erythrocytes; Humans; Membrane Proteins; Methylation; S-Adenosylmethionine

1984
Effects of various microsomal enzyme inducers on M-demethylation of chlorpromazine.
    Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1983, Volume: 24, Issue:8

    Topics: Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Biotransformation; Chlorodiphenyl (54% Chlorine); Chlorpromazine; Male; Methylation; Microsomes, Liver; Oxidoreductases, N-Demethylating; Pharmacology; Phenobarbital; Rats

1983
Calmodulin regulation of phospholipid and fatty acid methylation by rat liver microsomes.
    The Journal of biological chemistry, 1982, Aug-25, Volume: 257, Issue:16

    Topics: Adenosine Triphosphate; Animals; Calcium; Calcium-Binding Proteins; Calmodulin; Chlorpromazine; Egtazic Acid; Fatty Acids; Immunologic Techniques; Methylation; Microsomes, Liver; Phospholipids; Rats; Rats, Inbred Strains

1982
Rat tissue concentrations of chlorimipramine, chlorpromazine and their N-demethylated metabolites after a single oral dose of the parent compounds.
    The Journal of pharmacy and pharmacology, 1995, Volume: 47, Issue:9

    Topics: Adipose Tissue; Administration, Oral; Animals; Antidepressive Agents, Tricyclic; Brain; Chlorpromazine; Chromatography, Gas; Clomipramine; Erythrocytes; Kidney; Liver; Lung; Male; Methylation; Myocardium; Rats; Rats, Sprague-Dawley; Spleen; Tissue Distribution

1995
N-demethylation of phenothiazines by lipoxygenase from soybean and human term placenta in the presence of hydrogen peroxide.
    Teratogenesis, carcinogenesis, and mutagenesis, 1999, Volume: 19, Issue:3

    Topics: Chlorpromazine; Dose-Response Relationship, Drug; Glycine max; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Lipoxygenase; Methylation; Phenothiazines; Placenta; Time Factors

1999
Human term placental lipoxygenase-mediated N-demethylation of phenothiazines and insecticides in the presence of linoleic acid.
    Placenta, 2000, Volume: 21, Issue:7

    Topics: Carbamates; Cations; Chlorpromazine; Female; Formaldehyde; Free Radicals; Humans; Hydrogen-Ion Concentration; Insecticides; Linoleic Acid; Lipoxygenase; Methylation; Phenothiazines; Phenylcarbamates; Placenta; Pregnancy; Substrate Specificity

2000
Inhibition of the methylation of histamine in cat brain.
    The Journal of physiology, 1961, Volume: 159

    Topics: Animals; Brain; Cats; Chlorpromazine; Copper; Histamine; Humans; Methylation

1961
INHIBITION OF HISTAMINE METHYLATION IN VIVO BY DRUGS.
    Biochemical pharmacology, 1964, Volume: 13

    Topics: Carbon Isotopes; Chlorpromazine; Chromatography; Guanidines; Hallucinogens; Histamine; Histamine Release; Hydrazines; Imipramine; Indoles; Metabolism; Methylation; Mice; Pharmacology; Research; Reserpine; Serotonin; Tripelennamine

1964
Enhanced photo(geno)toxicity of demethylated chlorpromazine metabolites.
    Toxicology and applied pharmacology, 2016, 12-15, Volume: 313

    Topics: Antipsychotic Agents; Chlorpromazine; Comet Assay; Electron Spin Resonance Spectroscopy; Electrophoresis, Agar Gel; Methylation

2016
Investigation of metabolite-protein interactions by transient absorption spectroscopy and in silico methods.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2020, Feb-05, Volume: 226

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antipsychotic Agents; Binding Sites; Carbazoles; Chlorpromazine; Drug Interactions; Humans; Hydrogen Bonding; Inactivation, Metabolic; Methylation; Molecular Docking Simulation; Molecular Dynamics Simulation; Protein Binding; Serum Albumin, Human; Spectrophotometry, Ultraviolet; Stereoisomerism

2020